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ARVO Annual Meeting Abstract June 2015

Nitroxide free radicals protect macular xanthophylls against chemical destruction (bleaching) during lipid peroxidation

Mariusz Zareba; Janice M Burke; Witold Karol Subczynski

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4669.

Retinal Cell Biology August 2014

Photic Injury to Cultured RPE Varies Among Individual Cells in Proportion to Their Endogenous Lipofuscin Content as Modulated by Their Melanosome Content

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Mariusz Zareba; Christine M. B. Skumatz; Tadeusz J. Sarna; Janice M. Burke
TAGS: granules, lipofuscin, melanosomes, stress, retinal pigment cell, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):4982-4990. https://doi.org/10.1167/iovs.14-14310

Retinal Cell Biology March 2013

Photosensitized Oxidative Stress to ARPE-19 Cells Decreases Protein Receptors that Mediate Photoreceptor Outer Segment Phagocytosis

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Magdalena M. Olchawa; Anja M. Herrnreiter; Christine M. B. Skumatz; Mariusz Zareba; Tadeusz J. Sarna; Janice M. Burke
TAGS: integrins, oxidative stress, phagocytosis, photoreceptors, proteins, receptor, stress, phototoxic dermatitis, photosensitizing agents, actins
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):2276-2287. https://doi.org/10.1167/iovs.12-11154

Retinal Cell Biology January 2013

Oxidative Stress Increases HO-1 Expression in ARPE-19 Cells, But Melanosomes Suppress the Increase When Light Is the Stressor

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Anna Pilat; Anja M. Herrnreiter; Christine M. B. Skumatz; Tadeusz Sarna; Janice M. Burke
TAGS: antioxidants, enzymes, melanosomes, proteins, oxidative stress, stress, stressor, phagocytosis
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):47-56. https://doi.org/10.1167/iovs.12-11153

ARVO Annual Meeting Abstract March 2012

The Ratio of Melanosome to Lipofuscin Granule Number, Not Lipofuscin Content Alone, Determines the Susceptibility of Individual RPE Cells to Lethal Photic Stress in vitro

Mariusz Zareba; Tadeusz J. Sarna; Janice M. Burke

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4273.

ARVO Annual Meeting Abstract March 2012

Oxidative Stress to ARPE-19 Cells by Treatment with Photosensitizers plus Light Decreases Protein Receptors that Mediate Outer Segment Phagocytosis

Magdalena M. Olchawa; Anja Herrnreiter; Christine Skumatz; Janice M. Burke; Tadeusz J. Sarna

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4775.

ARVO Annual Meeting Abstract March 2012

Oxidative Stress Increases HO-1 in ARPE-19 Cells but Melanosomes Suppress the Increase when Light is the Stressor

Anna K. Pilat; Anja Herrnreiter; Christine Skumatz; Janice M. Burke; Tadeusz J. Sarna

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4776.

ARVO Annual Meeting Abstract March 2012

Do Melanosomes Release or Bind Iron Ions inside RPE-Derived Cells?

Patrycja Kaczara; Anna K. Pilat; Anja Herrnreiter; Christine M. Skumatz; Tadeusz J. Sarna; Janice M. Burke

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4777.

ARVO Annual Meeting Abstract April 2011

RPE Melanosomes Protect Cells against Non-Photic Stress

Mariusz Zareba; Patrycja Kaczara; Christine Skumatz; Tadeusz J. Sarna; Magdalena Olchawa; Anna Pilat; Janice M. Burke

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4424.

ARVO Annual Meeting Abstract April 2010

Role of Lipofuscin in Differential Sensitivity of RPE Cells to Sub-Lethal and Lethal Photic Stress

M. Zareba; T. J. Sarna; J. M. Burke

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):468.

ARVO Annual Meeting Abstract April 2009

Oxidative Stress Induces Loss of Proteins Mediating Organelle Motility From RPE Phagosomes and Impairs Their Movement

M. Zareba; A. Herrnreiter; J. M. Burke

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2154.

Retinal Cell Biology April 2009

Sublethal Photic Stress and the Motility of RPE Phagosomes and Melanosomes

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Janice M. Burke; Mariusz Zareba
TAGS: cell motility, melanosomes, organelles, phagosomes, stress, granules, blue light
Invest. Ophthalmol. Vis. Sci.. 2009; 50(4):1940-1947. https://doi.org/10.1167/iovs.08-2671

Biochemistry and Molecular Biology July 2008

Human RPE Melanosomes Protect from Photosensitized and Iron-Mediated Oxidation but Become Pro-oxidant in the Presence of Iron upon Photodegradation

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Bartosz Różanowski; Janice M. Burke; Michael E. Boulton; Tadeusz Sarna; Małgorzata Różanowska
TAGS: iron, melanins, melanosomes, oxidation, phototoxic dermatitis, oxidants, ions, granules, oxygen
Invest. Ophthalmol. Vis. Sci.. 2008; 49(7):2838-2847. https://doi.org/10.1167/iovs.08-1700

ARVO Annual Meeting Abstract May 2008

A Role for the Retinal Pigmented Epithelium in Ocular Inflammation

J. Tombran-Tink; K. Leung; J. M. Burke; C. J. Barnstable

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4761.

ARVO Annual Meeting Abstract May 2008

Age-Related Changes in the Expression of ZnT and ZIP Zinc Transporters Human RPE and Their Regulation by Neurotrophic Factors

K. Leung; K. K. Erickson; M. J. Seiler; J. M. Burke; C. J. Barnstable; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5544.

ARVO Annual Meeting Abstract May 2008

Sub-Lethal Photic Stress Impairs Organelle Translocation in RPE Cells

M. Zareba; J. M. Burke

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5930.

ARVO Annual Meeting Abstract May 2008

The Effects of Photobleached and Untreated Bovine RPE Melanosomes on Photoinduced Peroxidation of Lipids

T. J. Sarna; A. Zadlo; J. M. Burke

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5941.

ARVO Annual Meeting Abstract May 2007

Photobleaching of RPE Melanosomes Affects Protein Oxidation and Susceptibility of Melanosome-Filled RPE Cells to Photic Stress

J. M. Burke; M. Zareba; M. M. Henry; T. Sarna

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5071.

ARVO Annual Meeting Abstract May 2007

Human RPE Cells Aged in vitro Differ From Young Cells in Sensitivity to Oxidative Stress - But the Aging Effect is not Simple and the Type of Stress Matters

C. Nischler; M. Zareba; M. M. Henry; C. M. Skumatz; T. Sarna; J. M. Burke

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5074.

ARVO Annual Meeting Abstract May 2007

The Effect of Photobleaching of Bovine RPE Melanosomes on Their Photoprotective and Antioxidant Properties

T. J. Sarna; A. Zadlo; G. Szewczyk; M. B. Rozanowska; J. M. Burke

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5079.

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Nitroxide free radicals protect macular xanthophylls against chemical destruction (bleaching) during lipid peroxidation

Photic Injury to Cultured RPE Varies Among Individual Cells in Proportion to Their Endogenous Lipofuscin Content as Modulated by Their Melanosome Content

Photosensitized Oxidative Stress to ARPE-19 Cells Decreases Protein Receptors that Mediate Photoreceptor Outer Segment Phagocytosis

Oxidative Stress Increases HO-1 Expression in ARPE-19 Cells, But Melanosomes Suppress the Increase When Light Is the Stressor

The Ratio of Melanosome to Lipofuscin Granule Number, Not Lipofuscin Content Alone, Determines the Susceptibility of Individual RPE Cells to Lethal Photic Stress in vitro

Oxidative Stress to ARPE-19 Cells by Treatment with Photosensitizers plus Light Decreases Protein Receptors that Mediate Outer Segment Phagocytosis

Oxidative Stress Increases HO-1 in ARPE-19 Cells but Melanosomes Suppress the Increase when Light is the Stressor

Do Melanosomes Release or Bind Iron Ions inside RPE-Derived Cells?

RPE Melanosomes Protect Cells against Non-Photic Stress

Role of Lipofuscin in Differential Sensitivity of RPE Cells to Sub-Lethal and Lethal Photic Stress

Oxidative Stress Induces Loss of Proteins Mediating Organelle Motility From RPE Phagosomes and Impairs Their Movement

Sublethal Photic Stress and the Motility of RPE Phagosomes and Melanosomes

Human RPE Melanosomes Protect from Photosensitized and Iron-Mediated Oxidation but Become Pro-oxidant in the Presence of Iron upon Photodegradation

A Role for the Retinal Pigmented Epithelium in Ocular Inflammation

Age-Related Changes in the Expression of ZnT and ZIP Zinc Transporters Human RPE and Their Regulation by Neurotrophic Factors

Sub-Lethal Photic Stress Impairs Organelle Translocation in RPE Cells

The Effects of Photobleached and Untreated Bovine RPE Melanosomes on Photoinduced Peroxidation of Lipids

Photobleaching of RPE Melanosomes Affects Protein Oxidation and Susceptibility of Melanosome-Filled RPE Cells to Photic Stress

Human RPE Cells Aged in vitro Differ From Young Cells in Sensitivity to Oxidative Stress - But the Aging Effect is not Simple and the Type of Stress Matters

The Effect of Photobleaching of Bovine RPE Melanosomes on Their Photoprotective and Antioxidant Properties

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