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ARVO Annual Meeting Abstract June 2024

Mitochondrial Dysfunction in Exfoliation Glaucoma

Arunkumar Venkatesan; Nileyma Castro; Jose Mario Wolosin; Preethi S Ganapathy; Jamin Brown; Anthony DeVincentis III; Sandra Sieminski; Audrey M Bernstein

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6461.

ARVO Annual Meeting Abstract June 2023

Loxl1 protein aggregation and impaired mitochondrial bioenergetics in exfoliation glaucoma

Arunkumar Venkatesan; Nileyma Castro; j. mario wolosin; Audrey M Bernstein

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1365.

ARVO Annual Meeting Abstract June 2023

TGFβ1-driven SMAD2/3 phosphorylation and myofibroblast emergence are fully dependent on the TGFβ1 pre-activation of MAPKs and Maternal Leucine Zipper Kinase.

Zheng Wang; Nileyma Castro; Audrey M Bernstein; j. mario wolosin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3150.

ARVO Annual Meeting Abstract June 2023

A keratin 12 expression-based analysis of stem-precursor cells and differentiation in the limbal-corneal epithelium using single-cell RNA-Seq data.

j. mario wolosin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3593.

Cornea February 2022

The c-Myc Oncogene Maintains Corneal Epithelial Architecture at Homeostasis, Modulates p63 Expression, and Enhances Proliferation During Tissue Repair

PDF

Céline Portal; Zheng Wang; Donald K. Scott; J. Mario Wolosin; Carlo Iomini
TAGS: ablation, c-myc genes, cornea, corneal epithelium, epithelium, homeostasis, mice, oncogenes, tp63 gene, wound healing
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):3. https://doi.org/10.1167/iovs.63.2.3

ARVO Annual Meeting Abstract July 2019

The XFG- Associated Deaminase LOXL1 Is An Intrinsically Disordered Protein With A High Aggregative Ability.

J. Mario Wolosin; Zheng Wang; Robert Ritch; Audrey M Bernstein

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6159.

ARVO Annual Meeting Abstract July 2019

Pre-activated p38 inhibits phosphorylation of SMAD2 by TGFβ1-activated TGFβR in corneal fibroblasts

Zheng Wang; Audrey M Bernstein; J. Mario Wolosin

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4680.

ARVO Annual Meeting Abstract July 2018

K14 + epithelial-targeted Myc ablation induces ΔDNp63 overexpression in corneal epithelium.

J Mario Wolosin; Quin Liu; Zheng Wang; Celine Portal; Daniel K Scott; Carlo Iomini

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2243.

ARVO Annual Meeting Abstract July 2018

LOXL1 protein aggregation in Exfoliation Glaucoma

Audrey M Bernstein; Zheng Wang; Marc Ridilla; Robert Ritch; J. Mario Wolosin

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3535.

ARVO Annual Meeting Abstract June 2017

Effect of Wnt/β-Catenin Signaling Modifiers on Self-Renewal of Human Limbal Epithelial Progenitor Cells Grown from Limbal Biopsy Explants

Hyun Jung Lee; J Mario Wolosin; So-Hyang Chung

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):959.

ARVO Annual Meeting Abstract June 2017

LOXL1 And Misfolded Protein Processing Pathways In XFS Glaucoma Cells.

J Mario Wolosin; Zheng Wang; Stephanie Gillespie; Shozer Dawn; Robert Ritch; Audrey M Bernstein

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4601.

ARVO Annual Meeting Abstract September 2016

Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients

J Mario Wolosin; Andy Want; Stephanie Gillespie; Zheng Wang; Robert Ritch; Audrey M Bernstein

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3005.

ARVO Annual Meeting Abstract June 2015

Impaired Lysosomal and Mitochondrial Function in Exfoliation Glaucoma

Andrew Want; Stephanie Gillespie; J Mario Wolosin; Robert Ritch; Audrey Bernstein

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1695.

ARVO Annual Meeting Abstract June 2015

Inhibition of TGFβ-SMAD2/3 Signaling Allows Limbal Explant Outgrowth Culture in Chemically Defined, Xeno-free Medium.

J Mario Wolosin; Aldo Zamudio; So-Hyang Chung; Zheng Wang

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5619.

ARVO Annual Meeting Abstract March 2012

TGF-β1 Induced Rises in Il-6 Release and α-sma Expression Depend On ROS Formation and TRPV1 Activation

Yuanquan Yang; Hua Yang; Zheng Wang; J Mario Wolosin; Peter S. Reinach

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1085.

ARVO Annual Meeting Abstract March 2012

In Human Corneal Epithelial Cells TLR2/4 Innate Immune Responses are Fully Dependent on TRPV1 Activity Mediated Through both MyD88-dependent and Independent Signaling Pathways

Zheng Wang; Hua Yang; J. Mario Wolosin; Peter S. Reinach

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1832.

Cornea June 2011

ABCG2-Dependent Dye Exclusion Activity and Clonal Potential in Epithelial Cells Continuously Growing for 1 Month from Limbal Explants

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Ozlëm Barut Selver; Alexander Barash; Mohaned Ahmed; J. Mario Wolosin
TAGS: body tissue, dyes, epithelial cells, oryctolagus cuniculus, toxic effect, epithelium, flow cytometry
Invest. Ophthalmol. Vis. Sci.. 2011; 52(7):4330-4337. https://doi.org/10.1167/iovs.10-5897

ARVO Annual Meeting Abstract April 2011

ABCG2 Transport Activity and Clonal Potential in Epithelial Cells Continuously Growing for One Month from Limbal Explants

Alexander Barash; Ozlem Barut Selver; Mohaned Ahmed; J Mario Wolosin

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5133.

Cornea November 2010

Dependence of Resolvin-Induced Increases in Corneal Epithelial Cell Migration on EGF Receptor Transactivation

PDF

Fan Zhang; Hua Yang; Zan Pan; Zheng Wang; J. Mario Wolosin; Per Gjorstrup; Peter S. Reinach
TAGS: epidermal growth factor receptors, trans-activation (genetics), mitogen-activated protein kinase p38, cell motility, corneal epithelial cells, proto-oncogene proteins c-akt, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2010; 51(11):5601-5609. https://doi.org/10.1167/iovs.09-4468

Cornea December 2009

Differential Gene Expression in the Pig Limbal Side Population: Implications for Stem Cell Cycling, Replication, and Survival

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M. A. Murat Akinci; Helen Turner; Maria Taveras; J. Mario Wolosin
TAGS: gene expression, genes, rna, stem cells, conjunctiva
Invest. Ophthalmol. Vis. Sci.. 2009; 50(12):5630-5638. https://doi.org/10.1167/iovs.09-3791

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Mitochondrial Dysfunction in Exfoliation Glaucoma

Loxl1 protein aggregation and impaired mitochondrial bioenergetics in exfoliation glaucoma

TGFβ1-driven SMAD2/3 phosphorylation and myofibroblast emergence are fully dependent on the TGFβ1 pre-activation of MAPKs and Maternal Leucine Zipper Kinase.

A keratin 12 expression-based analysis of stem-precursor cells and differentiation in the limbal-corneal epithelium using single-cell RNA-Seq data.

The c-Myc Oncogene Maintains Corneal Epithelial Architecture at Homeostasis, Modulates p63 Expression, and Enhances Proliferation During Tissue Repair

The XFG- Associated Deaminase LOXL1 Is An Intrinsically Disordered Protein With A High Aggregative Ability.

Pre-activated p38 inhibits phosphorylation of SMAD2 by TGFβ1-activated TGFβR in corneal fibroblasts

K14 + epithelial-targeted Myc ablation induces ΔDNp63 overexpression in corneal epithelium.

LOXL1 protein aggregation in Exfoliation Glaucoma

Effect of Wnt/β-Catenin Signaling Modifiers on Self-Renewal of Human Limbal Epithelial Progenitor Cells Grown from Limbal Biopsy Explants

LOXL1 And Misfolded Protein Processing Pathways In XFS Glaucoma Cells.

Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients

Impaired Lysosomal and Mitochondrial Function in Exfoliation Glaucoma

Inhibition of TGFβ-SMAD2/3 Signaling Allows Limbal Explant Outgrowth Culture in Chemically Defined, Xeno-free Medium.

TGF-β1 Induced Rises in Il-6 Release and α-sma Expression Depend On ROS Formation and TRPV1 Activation

In Human Corneal Epithelial Cells TLR2/4 Innate Immune Responses are Fully Dependent on TRPV1 Activity Mediated Through both MyD88-dependent and Independent Signaling Pathways

ABCG2-Dependent Dye Exclusion Activity and Clonal Potential in Epithelial Cells Continuously Growing for 1 Month from Limbal Explants

ABCG2 Transport Activity and Clonal Potential in Epithelial Cells Continuously Growing for One Month from Limbal Explants

Dependence of Resolvin-Induced Increases in Corneal Epithelial Cell Migration on EGF Receptor Transactivation

Differential Gene Expression in the Pig Limbal Side Population: Implications for Stem Cell Cycling, Replication, and Survival

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