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ARVO Annual Meeting Abstract June 2022

A novel method to determine axon-level IOP-induced insult

Manik Bansal; Fuqiang Zhong; Yi Hua; Bingrui Wang; Juan Reynaud; Brad Fortune; Ian Sigal

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):811. doi:

ARVO Annual Meeting Abstract June 2022

Detecting glaucomatous loss in the photopic full-field electroretinogram (ERG): influence of chromatic contrast, flash duration and flicker frequency

Michaela Dunn; Grant Cull; Juan Reynaud; Dawn Jennings; Trinity Holthausen; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):639 – A0379. doi:

ARVO Annual Meeting Abstract June 2022

Pharmacodynamic response of optic nerve head (ONH) tissue blood flow measured by laser speckle flowgraphy (LSFG) after administration of PER-001, an endothelin receptor antagonist

Grant Cull; Crystal Jadach; Juan Reynaud; Kristine Ly; Michaela Dunn; Dawn Jennings; Trinity Holthausen; Howard Lockwood; Stuart Keith Gardiner; Lin Wang; Jennifer Wilk; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4029 – A0414. doi:

ARVO Annual Meeting Abstract June 2022

Pharmacodynamic response of optic nerve head (ONH) vasculature measured by OCT-angiography (OCTA) after administration of the endothelin receptor antagonist PER-001

Brad Fortune; Grant Cull; Crystal Jadach; Kristine Ly; Michaela Dunn; Dawn Jennings; Trinity Holthausen; Howard Lockwood; Stuart Keith Gardiner; Lin Wang; Jennifer Wilk; Juan Reynaud

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3496. doi:

ARVO Annual Meeting Abstract June 2022

Decreased retrolaminar Myelin protein expression in Non-Human Primate (NHP) Early Experimental Glaucoma (EG) is accompanied by increased Iba1(+) cell counts and decreased GFAP signal intensity

Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart Keith Gardiner; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):933 – A0402. doi:

ARVO Annual Meeting Abstract June 2022

Correlating longitudinal Optical Coherence Tomography (OCT) structural change to retrolaminar myelin-related protein alteration in non-human primate (NHP) early experimental glaucoma (EG)

Hongli Yang; Priya Chaudhary; Cheri Stowell; Juan Reynaud; Stuart Keith Gardiner; Galen Williams; Imee Williams; Nicholas Marsh-Armstrong; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3095. doi:

ARVO Annual Meeting Abstract June 2021

In-vivo evidence of lamina cribrosa deformations induced by chronically elevated IOP in non-human primates

Ian A Sigal; Fuqiang Zhong; Yi Hua; Junchao Wei; Manik Bansal; Juan Reynaud; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1862. doi:

ARVO Annual Meeting Abstract June 2021

In-vivo evidence of increased lamina cribrosa compliance at onset of experimental glaucoma in nonhuman primates

Fuqiang Zhong; Yi Hua; Junchao Wei; Manik Bansal; Juan Reynaud; Brad Fortune; Ian A Sigal

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1827. doi:

ARVO Annual Meeting Abstract June 2021

Diagnostic accuracy of inner retinal layer thickness and reflectance intensity measurements assessed in posterior pole OCT scans of healthy and glaucomatous eyes

Hongli Yang; Juan Reynaud; Glen P Sharpe; Dawn Jennings; Cindy Albert; Galen Williams; Xiue Jiang; Shaban Demirel; Steven L Mansberger; Jayme R Vianna; Marcelo Nicolela; Balwantray C Chauhan; Claude F Burgoyne; Stuart Keith Gardiner; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1836. doi:

ARVO Annual Meeting Abstract June 2020

Does loss of vasculature contribute to early stage glaucomatous thinning of the retinal nerve fiber layer (RNFL)?

Brad Fortune; Juan Reynaud; Christy Hardin; Laura J Wilsey; Taylor Sund; Stuart Keith Gardiner; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3531. doi:

ARVO Annual Meeting Abstract June 2020

Comparison of glaucoma diagnostic OCT parameters derived directly from circumpapillary and radial B-scans versus from raster grid scans

Christy Hardin; Juan Reynaud; Laura J Wilsey; Taylor Sund; Stuart Keith Gardiner; Claude F Burgoyne; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4792. doi:

ARVO Annual Meeting Abstract June 2020

The relation between blood flow within the remaining peripapillary vasculature and functional progression in glaucoma

Stuart Keith Gardiner; Grant Cull; Juan Reynaud; Steven L Mansberger; Brad Fortune; Lin Wang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):620. doi:

ARVO Annual Meeting Abstract June 2020

Diagnostic accuracy of individual and combined retinal layer thickness measurements assessed at each pixel within posterior pole OCT scans of healthy and glaucomatous eyes

Hongli Yang; Juan Reynaud; Glen P Sharpe; Dawn Jennings; Cindy Albert; Galen Williams; Xiue Jiang; Shaban Demirel; Steven L Mansberger; Jayme R Vianna; Marcelo T Nicolela; Stuart Keith Gardiner; Balwantray C Chauhan; Claude F Burgoyne; Brad Fortune

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3935. doi:

ARVO Annual Meeting Abstract July 2019

Frequent non-intact axons and extensive extracellular debris in the optic nerve head at very early stages of non-human primate experimental glaucoma

Nicholas Marsh-Armstrong; Catherine Hou; Cheri Stowell; Imee Williams; Eric Bushong; Howard Lockwood; Juan Reynaud; Mark Ellisman; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):670. doi:

ARVO Annual Meeting Abstract July 2019

Improved Detection of Optical Coherence Tomography (OCT) Structural Abnormality in Glaucoma (GL) with Combined Sectoral Rim and Retinal Nerve Fiber Layer (RNFL) Criteria

Hongli Yang; Haomin Luo; Christy A Hardin; Cindy Albert; Jayme Vianna; Glen Sharpe; Juan Reynaud; Shaban Demirel; Steven L Mansberger; Brad Fortune; Stuart Keith Gardiner; Balwantray C Chauhan; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4818. doi:

ARVO Annual Meeting Abstract July 2019

Machine Learning-Based Quantification of Axonal Damage in Glaucomatous Rat Optic Nerves

Bailey Hannon; Matthew Ritch; Robert Christian Ford; Arthur Thomas Read; Kristin Gao; Eva L. Dyer; Juan Reynaud; Grant Cull; Claude F Burgoyne; Machelle T Pardue; C Ross Ethier

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2854. doi:

ARVO Annual Meeting Abstract July 2019

Serial Block-Face Scanning EM (SBEM) Provides Evidence for Retrolaminar Demyelination of Structurally Intact Axons in Non-Human Primate (NHP) Early Experimental Glaucoma (EG)

Cheri Stowell; Eric Bushong; Howard Lockwood; Imee Williams; Juan Reynaud; Stuart Keith Gardiner; Nicholas Marsh-Armstrong; Mark Ellisman; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5658. doi:

ARVO Annual Meeting Abstract July 2019

Optic nerve head (ONH) hypercompliance and blood flow autoregulation dysfunction detected by OCT-angiography (OCTA) in early-stage experimental glaucoma (EG)

Brad Fortune; Juan Reynaud; Christy A Hardin; Grant Cull; Lin Wang; Claude F Burgoyne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4822. doi:

ARVO Annual Meeting Abstract July 2019

Lamina cribrosa depth and mean cup depth changes in the setting of trabeculectomy in patients with open angle glaucoma

Facundo Gregorio Sanchez; David Sebastian Sanders; Brad Fortune; Stuart Keith Gardiner; Juan Reynaud; Eugene Lowry; Steven L Mansberger

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5612. doi:

ARVO Annual Meeting Abstract July 2018

Automated Segmentation of the Anterior Lamina Cribrosa Surface (ALCS) within Optic Nerve Head (ONH) Optical Coherence Tomography (OCT) B-scans

Haomin Luo; Julian Weichsel; Stuart Keith Gardiner; Juan Reynaud; Christy Hardin; Cindy Albert; Jayme R Vianna; Glen Sharpe; Victoria R Lanoe; Jack Quach; Shaban Demirel; Brad Fortune; Balwantray C Chauhan; Claude F Burgoyne; Hongli Yang

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2097. doi:

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A novel method to determine axon-level IOP-induced insult

Detecting glaucomatous loss in the photopic full-field electroretinogram (ERG): influence of chromatic contrast, flash duration and flicker frequency

Pharmacodynamic response of optic nerve head (ONH) tissue blood flow measured by laser speckle flowgraphy (LSFG) after administration of PER-001, an endothelin receptor antagonist

Pharmacodynamic response of optic nerve head (ONH) vasculature measured by OCT-angiography (OCTA) after administration of the endothelin receptor antagonist PER-001

Decreased retrolaminar Myelin protein expression in Non-Human Primate (NHP) Early Experimental Glaucoma (EG) is accompanied by increased Iba1(+) cell counts and decreased GFAP signal intensity

Correlating longitudinal Optical Coherence Tomography (OCT) structural change to retrolaminar myelin-related protein alteration in non-human primate (NHP) early experimental glaucoma (EG)

In-vivo evidence of lamina cribrosa deformations induced by chronically elevated IOP in non-human primates

In-vivo evidence of increased lamina cribrosa compliance at onset of experimental glaucoma in nonhuman primates

Diagnostic accuracy of inner retinal layer thickness and reflectance intensity measurements assessed in posterior pole OCT scans of healthy and glaucomatous eyes

Does loss of vasculature contribute to early stage glaucomatous thinning of the retinal nerve fiber layer (RNFL)?

Comparison of glaucoma diagnostic OCT parameters derived directly from circumpapillary and radial B-scans versus from raster grid scans

The relation between blood flow within the remaining peripapillary vasculature and functional progression in glaucoma

Diagnostic accuracy of individual and combined retinal layer thickness measurements assessed at each pixel within posterior pole OCT scans of healthy and glaucomatous eyes

Frequent non-intact axons and extensive extracellular debris in the optic nerve head at very early stages of non-human primate experimental glaucoma

Improved Detection of Optical Coherence Tomography (OCT) Structural Abnormality in Glaucoma (GL) with Combined Sectoral Rim and Retinal Nerve Fiber Layer (RNFL) Criteria

Machine Learning-Based Quantification of Axonal Damage in Glaucomatous Rat Optic Nerves

Serial Block-Face Scanning EM (SBEM) Provides Evidence for Retrolaminar Demyelination of Structurally Intact Axons in Non-Human Primate (NHP) Early Experimental Glaucoma (EG)

Optic nerve head (ONH) hypercompliance and blood flow autoregulation dysfunction detected by OCT-angiography (OCTA) in early-stage experimental glaucoma (EG)

Lamina cribrosa depth and mean cup depth changes in the setting of trabeculectomy in patients with open angle glaucoma

Automated Segmentation of the Anterior Lamina Cribrosa Surface (ALCS) within Optic Nerve Head (ONH) Optical Coherence Tomography (OCT) B-scans

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