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ARVO Annual Meeting Abstract June 2022

The safety of APX3330, an oral drug candidate for the treatment of diabetic eye disease, in the ongoing masked 24-week ZETA-1 Phase 2 clinical trial

David S Boyer; Mitch Brigell; Ajay Kolli; Kavon Rahmani; Audrey Lazar; Mina Sooch; Ronil Patel; Eliot Lazar; Jay Stuart Pepose; Mark R Kelley

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):675 – F0129. doi:

ARVO Annual Meeting Abstract June 2022

Phentolamine Ophthalmic Solution Reverses Pharmacologically Induced Mydriasis in Healthy Subjects: Subgroup Analyses in the Pivotal Phase 3 MIRA-2 Randomized Controlled Trial

Douglas Devries; Jay Stuart Pepose; Ajay Kolli; Kavon Rahmani; Ronil Patel; Mina Sooch; Eliot Lazar; Amar Khatri; Mitch Brigell

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1300 – F0115. doi:

ARVO Annual Meeting Abstract June 2022

VEGA-1: Phentolamine Ophthalmic Solution as a Single Agent Improves Distance-Corrected Near Visual Acuity in Patients with Presbyopia

James Katz; Eliot Lazar; Ajay Kolli; Ronil Patel; Kavon Rahmani; Mina Sooch; Mitchell G Brigell; Jay Stuart Pepose

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1813 – F0429. doi:

ARVO Annual Meeting Abstract June 2022

The Efficacy of Phentolamine Ophthalmic Solution and Low-Dose Pilocarpine to Improve Distance-Corrected Intermediate Visual Acuity in Patients with Presbyopia

Jay Stuart Pepose; Ajay Kolli; Ronil Patel; Kavon Rahmani; Mina Sooch; Mitchell G Brigell; Eliot Lazar

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1809 – F0425. doi:

ARVO Annual Meeting Abstract June 2020

Phentolamine mesylate ophthalmic solution provides long lasting pupil modulation and improves visual acuity

Jay S Pepose; Bill Pitlick; Alan Meyer; Reda Jaber; Konstantinos Charizanis; Charles Slonim; Eliot Lazar; Marguerite McDonald; Mina Sooch

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5100. doi:

ARVO Annual Meeting Abstract July 2018

Evaluating Visual Outcomes in Small-Aperture IOL, Accommodating IOL, and Multifocal IOL Patients

Ling Lin; Jay Stuart Pepose; Srividhya Vilupuru

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2198. doi:

ARVO Annual Meeting Abstract September 2016

Evaluating the effect of corneal inlay implantation depth on visual outcomes and stability

Ling Lin; Srividhya Vilupuru; Jay Stuart Pepose

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract March 2012

A Three Arm Prospective Clinical Comparison of Three FDA-Approved Presbyopia-Correcting Intraocular Lenses

Jay S. Pepose; Mujtaba A. Qazi

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1368. doi:

ARVO Annual Meeting Abstract April 2011

Application of Direct Measurement of IOL Position via Tomography for Back-Calculating Corneal and IOL Power Following Myopic LASIK

Miranda Bishara; Mujtaba A. Qazi; Li Wang; Ashraf M. Mahmoud; Cynthia J. Roberts; Douglas D. Koch; Jay S. Pepose

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5685. doi:

ARVO Annual Meeting Abstract April 2011

The Keratoconic Disease Classification Ability of Single Item and Spatial Distribution Metrics

Pete S. Kollbaum; Mujtaba A. Qazi; Ashraf M. Mahmoud; Martin Rickert; Ryan McGiffen; Michael D. Twa; Cynthia J. Roberts; Jay S. Pepose

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5168. doi:

Clinical Trials December 2010

An Objective Approach to Dry Eye Disease Severity

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Benjamin D. Sullivan; Diane Whitmer; Kelly K. Nichols; Alan Tomlinson; Gary N. Foulks; Gerd Geerling; Jay S. Pepose; Valerie Kosheleff; Allison Porreco; Michael A. Lemp
TAGS: dry eye syndromes, severity of illness
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6125-6130. doi: https://doi.org/10.1167/iovs.10-5390

ARVO Annual Meeting Abstract April 2010

Application of a Quantitative Method for Identifying Risk for Ectasia After LASIK in Normal, Suspect, and Ectatic Eyes

M. A. Qazi; A. M. Mahmoud; P. S. Kollbaum; M. D. Twa; C. J. Roberts; J. S. Pepose

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):2862. doi:

ARVO Annual Meeting Abstract April 2009

Application of Multiple Diagnostic Modalities to Differentiate Between Corneal Ectasia Types

G. Patel; M. A. Qazi; A. M. Mahmoud; P. S. Kollbaum; M. M. Merchea; C. J. Roberts; J. S. Pepose

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):5097. doi:

ARVO Annual Meeting Abstract May 2008

Influence of Region of Interest and Area Analyzed on the Calculation of the Highest Elevation Above the Posterior Best Fit Sphere

A. M. Mahmoud; M. D. Twa; J. S. Pepose; M. A. Qazi; P. Kollbaum; C. J. Roberts

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1019. doi:

ARVO Annual Meeting Abstract May 2007

Comparison of Ocular Response Analyzer Waveforms in LASEK and LASIK

J. S. Pepose; M. A. Qazi; A. M. Mahmoud; J. P. Sanderson; E. Y. Yoon; C. J. Roberts

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):5354. doi:

Cornea January 2000

IL-1 and TNF-α Are Important Factors in the Pathogenesis of Murine Recurrent Herpetic Stromal Keratitis

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Tammie Lee Keadle; Norio Usui; Keith Andrew Laycock; Judith Kelvin Miller; Jay S. Pepose; Patrick Michael Stuart
TAGS: cytokine, interleukin-1, pathogenesis, polymerase chain reaction, recurrence, stromal keratitis, tumor necrosis factors, ultraviolet b radiation, mice, cornea
Invest. Ophthalmol. Vis. Sci.. 2000; 41(1):96-102. doi:

Articles July 1995

T-cell mediated responses in a murine model of orthotopic corneal transplantation.

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C K Joo; J S Pepose; P M Stuart
TAGS: keratoplasty, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 1995; 36(8):1530-1540. doi:

Articles October 1994

In vitro propagation of primary and extended life span murine corneal endothelial cells.

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C K Joo; J S Pepose; T P Fleming
TAGS: cornea, endothelial cells, life span, mice
Invest. Ophthalmol. Vis. Sci.. 1994; 35(11):3952-3957. doi:

Articles May 1994

Herpes simplex viral vectors for therapeutic gene delivery to ocular tissues. Recent breakthroughs in the molecular genetics of ocular diseases.

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J S Pepose; D A Leib
TAGS: body tissue, eye diseases, genes, genetics, molecular, herpes simplex infection, simplexvirus, viral vector
Invest. Ophthalmol. Vis. Sci.. 1994; 35(6):2662-2666. doi:

Articles December 1993

Differential expression of the complement regulatory proteins in the human eye.

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N S Bora; C L Gobleman; J P Atkinson; J S Pepose; H J Kaplan
TAGS: complement system proteins, eye, regulatory protein
Invest. Ophthalmol. Vis. Sci.. 1993; 34(13):3579-3584. doi:

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The safety of APX3330, an oral drug candidate for the treatment of diabetic eye disease, in the ongoing masked 24-week ZETA-1 Phase 2 clinical trial

Phentolamine Ophthalmic Solution Reverses Pharmacologically Induced Mydriasis in Healthy Subjects: Subgroup Analyses in the Pivotal Phase 3 MIRA-2 Randomized Controlled Trial

VEGA-1: Phentolamine Ophthalmic Solution as a Single Agent Improves Distance-Corrected Near Visual Acuity in Patients with Presbyopia

The Efficacy of Phentolamine Ophthalmic Solution and Low-Dose Pilocarpine to Improve Distance-Corrected Intermediate Visual Acuity in Patients with Presbyopia

Phentolamine mesylate ophthalmic solution provides long lasting pupil modulation and improves visual acuity

Evaluating Visual Outcomes in Small-Aperture IOL, Accommodating IOL, and Multifocal IOL Patients

Evaluating the effect of corneal inlay implantation depth on visual outcomes and stability

A Three Arm Prospective Clinical Comparison of Three FDA-Approved Presbyopia-Correcting Intraocular Lenses

Application of Direct Measurement of IOL Position via Tomography for Back-Calculating Corneal and IOL Power Following Myopic LASIK

The Keratoconic Disease Classification Ability of Single Item and Spatial Distribution Metrics

An Objective Approach to Dry Eye Disease Severity

Application of a Quantitative Method for Identifying Risk for Ectasia After LASIK in Normal, Suspect, and Ectatic Eyes

Application of Multiple Diagnostic Modalities to Differentiate Between Corneal Ectasia Types

Influence of Region of Interest and Area Analyzed on the Calculation of the Highest Elevation Above the Posterior Best Fit Sphere

Comparison of Ocular Response Analyzer Waveforms in LASEK and LASIK

IL-1 and TNF-α Are Important Factors in the Pathogenesis of Murine Recurrent Herpetic Stromal Keratitis

T-cell mediated responses in a murine model of orthotopic corneal transplantation.

In vitro propagation of primary and extended life span murine corneal endothelial cells.

Herpes simplex viral vectors for therapeutic gene delivery to ocular tissues. Recent breakthroughs in the molecular genetics of ocular diseases.

Differential expression of the complement regulatory proteins in the human eye.

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