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Cornea June 2021

PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function

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Zhenying Shang; Chenxi Li; Xuemei Liu; Manhong Xu; Xiaomin Zhang; Xiaorong Li; Colin J. Barnstable; Shaozhen Zhao; Joyce Tombran-Tink
TAGS: cornea, mice, gene deletion, nerve supply
Invest. Ophthalmol. Vis. Sci.. 2021; 62(7):18. https://doi.org/10.1167/iovs.62.7.18

ARVO Annual Meeting Abstract July 2019

A novel sphingosine-1-phosphate agonist, HY-3011, protects porcine retinal pigment epithelial cells from 7-keto Cholesterol induced oxidative damage

Ji-Ye Jay Wei; Lily Yin; Celine Xin-Lin Wei; Joyce Tombran-Tink; Yue-Qing Tan; Colin Wei; Ling Xu; Colin J Barnstable; Cynthia Wei; Xiangdong He; Wei He

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5392.

ARVO Annual Meeting Abstract September 2016

Changes in Genome Expression and Mitochondrial Fission/Fusion Dynamics in RPE J Haplogroup May be Linked to AMD Susceptibility

Ana Rubin; Anzor Gvritishvili; Anna Salzberg; Yuka Imamura; Hannah Galvan; Lynn Mullen; Shari R Atilano; Cristina M Kenney; Joyce Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6527.

Retinal Cell Biology October 2014

PEDF Improves Mitochondrial Function in RPE Cells During Oxidative Stress

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Yuan He; Kar Wah Leung; Yuan Ren; Jinzhi Pei; Jian Ge; Joyce Tombran-Tink
TAGS: mitochondria, oxidative stress, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6742-6755. https://doi.org/10.1167/iovs.14-14696

ARVO Annual Meeting Abstract April 2011

Elevated Glucose Alters Cytoskeleton-tight Junction Dynamics In RPE Cells

Joyce Tombran-Tink; Yanling Liu; Anzor Grivitishvilli

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5937.

ARVO Annual Meeting Abstract April 2011

High Glucose Alters bFGF Secretion by RPE Cells

Anzor Gvritishvili; Yanling Liu; Joyce Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):5953.

ARVO Annual Meeting Abstract April 2010

PEDF78-121 Limits Oxidative Stress in RPE Cells Through Akt and Erk Signaling and Reduces Stress Promoted Expression of VEGFR1

A. Gvritishvili; Y. Liu; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):1442.

ARVO Annual Meeting Abstract April 2010

Corneal Application of PEDF78-121 Reduces Ischemic Injury in the Retina

L. Leo; A. Gvritishvili; Y. Liu; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):4516.

ARVO Annual Meeting Abstract April 2009

Mitochondrial Decay and Impairment of Antioxidant Defences in Aging Retinal Pigment Epithelial cells; Relevance to Age-Related Macular Degeneration

J. Tombran-Tink; J. Ge; Y. He

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2350.

ARVO Annual Meeting Abstract April 2009

ZIP2 and ZIP4 Zinc Transporters Regulate Intracellular Zinc Levels in Human RPE

K. Leung; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2916.

Glaucoma November 2008

Mitochondrial Defects and Dysfunction in Calcium Regulation in Glaucomatous Trabecular Meshwork Cells

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Yuan He; Jian Ge; Joyce Tombran-Tink
TAGS: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, calcium, glaucoma, mitochondria, open-angle glaucoma, pathophysiology, cyclophilins, peptidylprolyl isomerase, trabecular meshwork, regulation
Invest. Ophthalmol. Vis. Sci.. 2008; 49(11):4912-4922. https://doi.org/10.1167/iovs.08-2192

ARVO Annual Meeting Abstract May 2008

A PEDF N-Terminal Peptide Protects Against Retinal Degeneration in the Ins2Akita Mouse Model of Diabetic Retinopathy

K. K. Erickson; C. J. Barnstable; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1333.

ARVO Annual Meeting Abstract May 2008

A Defect in Mitochondrial Complex I Induces ROS Release and Degeneration in Trabecular Meshwork Cells of POAG Patients: Protection by Antioxidants

Y. He; K. W. Leung; Y. H. Zhang; S. Duan; J. Tombran-Tink; J. Ge

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):1626.

ARVO Annual Meeting Abstract May 2008

PEDF Supports the Growth of Retinal Progenitors and Embryonic Stem Cells

C. J. Barnstable; X. Liao; H. Li; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):3570.

ARVO Annual Meeting Abstract May 2008

A Role for the Retinal Pigmented Epithelium in Ocular Inflammation

J. Tombran-Tink; K. Leung; J. M. Burke; C. J. Barnstable

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4761.

ARVO Annual Meeting Abstract May 2008

Codon Optimization Increases Bacterial Expression of Functionally Active Pigment Epithelium Derived Factor (pedf)

A. G. Gvritishvili; K. Leung; C. J. Barnstable; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):4927.

ARVO Annual Meeting Abstract May 2008

Age-Related Changes in the Expression of ZnT and ZIP Zinc Transporters Human RPE and Their Regulation by Neurotrophic Factors

K. Leung; K. K. Erickson; M. J. Seiler; J. M. Burke; C. J. Barnstable; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):5544.

Glaucoma April 2008

Mitochondrial Complex I Defect Induces ROS Release and Degeneration in Trabecular Meshwork Cells of POAG Patients: Protection by Antioxidants

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Yuan He; Kar Wah Leung; Yue-Hong Zhang; Shan Duan; Xiu-Feng Zhong; Ru-Zhang Jiang; Zhan Peng; Joyce Tombran-Tink; Jian Ge
TAGS: antioxidants, cytochrome c, mitochondria, open-angle glaucoma, tissue degeneration, trabecular meshwork, cell death
Invest. Ophthalmol. Vis. Sci.. 2008; 49(4):1447-1458. https://doi.org/10.1167/iovs.07-1361

Retinal Cell Biology March 2008

Expression of ZnT and ZIP Zinc Transporters in the Human RPE and Their Regulation by Neurotrophic Factors

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Kar Wah Leung; Mugen Liu; Xuming Xu; Magdalene J. Seiler; Colin J. Barnstable; Joyce Tombran-Tink
TAGS: membrane transport proteins, nerve growth factors, retinal pigment cell, zinc, zinc transporter, regulation, mechlorethamine
Invest. Ophthalmol. Vis. Sci.. 2008; 49(3):1221-1231. https://doi.org/10.1167/iovs.07-0781

ARVO Annual Meeting Abstract May 2007

Pedf Binds With High Affinity to the Extracellular Domain of VEGF-R1 Receptor

C. J. Barnstable; L. Chen; S. S. M. Zhang; J. Tombran-Tink

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):38.

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PEDF Gene Deletion Disrupts Corneal Innervation and Ocular Surface Function

A novel sphingosine-1-phosphate agonist, HY-3011, protects porcine retinal pigment epithelial cells from 7-keto Cholesterol induced oxidative damage

Changes in Genome Expression and Mitochondrial Fission/Fusion Dynamics in RPE J Haplogroup May be Linked to AMD Susceptibility

PEDF Improves Mitochondrial Function in RPE Cells During Oxidative Stress

Elevated Glucose Alters Cytoskeleton-tight Junction Dynamics In RPE Cells

High Glucose Alters bFGF Secretion by RPE Cells

PEDF78-121 Limits Oxidative Stress in RPE Cells Through Akt and Erk Signaling and Reduces Stress Promoted Expression of VEGFR1

Corneal Application of PEDF78-121 Reduces Ischemic Injury in the Retina

Mitochondrial Decay and Impairment of Antioxidant Defences in Aging Retinal Pigment Epithelial cells; Relevance to Age-Related Macular Degeneration

ZIP2 and ZIP4 Zinc Transporters Regulate Intracellular Zinc Levels in Human RPE

Mitochondrial Defects and Dysfunction in Calcium Regulation in Glaucomatous Trabecular Meshwork Cells

A PEDF N-Terminal Peptide Protects Against Retinal Degeneration in the Ins2Akita Mouse Model of Diabetic Retinopathy

A Defect in Mitochondrial Complex I Induces ROS Release and Degeneration in Trabecular Meshwork Cells of POAG Patients: Protection by Antioxidants

PEDF Supports the Growth of Retinal Progenitors and Embryonic Stem Cells

A Role for the Retinal Pigmented Epithelium in Ocular Inflammation

Codon Optimization Increases Bacterial Expression of Functionally Active Pigment Epithelium Derived Factor (pedf)

Age-Related Changes in the Expression of ZnT and ZIP Zinc Transporters Human RPE and Their Regulation by Neurotrophic Factors

Mitochondrial Complex I Defect Induces ROS Release and Degeneration in Trabecular Meshwork Cells of POAG Patients: Protection by Antioxidants

Expression of ZnT and ZIP Zinc Transporters in the Human RPE and Their Regulation by Neurotrophic Factors

Pedf Binds With High Affinity to the Extracellular Domain of VEGF-R1 Receptor

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