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Lens June 2015

Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation

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Yuki Sugiyama; Elizabeth J. Shelley; Caroline Badouel; Helen McNeill; John W. McAvoy
TAGS: atypical, cadherins, epithelium, lens (device), lens epithelial cell, lens, crystalline, polarity, eye, mice
Invest. Ophthalmol. Vis. Sci.. 2015; 56(6):4099-4107. https://doi.org/10.1167/iovs.15-17008

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Inhibitory roles of Sprouty and Spred on FGF-induced lens cell proliferation and fiber differentiation.

Guannan Zhao; Chuck Bailey; Frank J Lovicu; John W McAvoy

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):746.

Lens March 2013

Wnt-Frizzled Signaling Is Part of an FGF-Induced Cascade that Promotes Lens Fiber Differentiation

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Lucy J. Dawes; Yuki Sugiyama; Ana S. Tanedo; Frank J. Lovicu; John W. McAvoy
TAGS: lens (device), lens, crystalline, signal transduction, epithelium
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1582-1590. https://doi.org/10.1167/iovs.12-11357

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

MAPK/ERK1/2 Signaling In Tgfß-induced Lens Epithelial To Mesenchymal Transition (EMT)

Frank J. Lovicu; Leila Mahmutovic; Magdalena Wojciechowski; Lucy J. Dawes; John W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1061.

ARVO Annual Meeting Abstract March 2012

WNT Signalling Pathway-Associated Proteins in Control and Keratoconus (KC) Tears and Corneas

Chris Hodge; Jing Jing You; Li Wen; Athena Roufas; Michele Madigan; John W. McAvoy; Gerard Sutton

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4221.

ARVO Annual Meeting Abstract March 2012

A Role for Wnt-Frizzled Signaling During FGF-induced Fiber Differentiation

John W. McAvoy; Lucy J. Dawes; Yuki Sugiyama; Li Wen; Frank J. Lovicu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6906.

ARVO Annual Meeting Abstract April 2011

Intraflagellar Transport Protein 88 Is Required For Ciliogenesis In Lens Cells

Yuki Sugiyama; Li Wen; Bradley K. Yoder; Frank J. Lovicu; John W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2767.

Lens July 2010

Growth Factor Signaling in Vitreous Humor–Induced Lens Fiber Differentiation

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Qian Wang; John W. McAvoy; Frank J. Lovicu
TAGS: growth factor, lens (device), lens, crystalline, signal transduction, vitreous body, proto-oncogene proteins c-akt, phosphorylation, platelet-derived growth factor
Invest. Ophthalmol. Vis. Sci.. 2010; 51(7):3599-3610. https://doi.org/10.1167/iovs.09-4797

ARVO Annual Meeting Abstract April 2010

Negative Regulation of Lens Cell Proliferation and Fiber Differentiation by Sprouty

F. J. Lovicu; E. H. Shin; M. A. Basson; G. R. Martin; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):2353.

ARVO Annual Meeting Abstract April 2010

Sprouty Prevents TGFβ-Induced Cataractogenesis

E. H. Shin; M. L. Robinson; M. A. Basson; G. Martin; J. W. McAvoy; F. J. Lovicu

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):3816.

ARVO Annual Meeting Abstract April 2009

A Role for Wnt/planar Cell Polarity Signaling in Development of Lens Three-Dimensional Architecture

J. W. McAvoy; Y. Sugiyama; R. J. W. Stump; A. Nguyen; Y. Chen; F. J. Lovicu

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3479.

ARVO Annual Meeting Abstract April 2009

A Role for Sprouty 1 and 2 as Antagonists of Growth Factor Signaling in the Lens

E.-H. H. Shin; J. Boros; J. W. McAvoy; M. L. Robinson; F. J. Lovicu

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4347.

ARVO Annual Meeting Abstract April 2009

A Role for Planar Cell Polarity (PCP) Signaling in Lens Fiber Differentiation Is Indicated by Asymmetric Localization of PCP Components

Y. Sugiyama; R. J. W. Stump; A. Nguyen; F. J. Lovicu; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4349.

ARVO Annual Meeting Abstract April 2009

Spreds: Sprouty-Related Proteins Antagonistic for Multiple Cell Signalling Pathways Are Expressed in the Lens and Eye

F. J. Lovicu; J. Boros; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4353.

ARVO Annual Meeting Abstract April 2009

Fgf Promotes Activation/Expression and Translocation of Wnt Signaling Components

R. J. Stump; Y. Sugiyama; A. Nguyen; F. J. Lovicu; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):4360.

ARVO Annual Meeting Abstract May 2008

Vitreous-Induced Lens Fiber Cell Differentiation: Regulation by Multiple Growth Factors via ERK1/2 and PI3-K Signaling

F. J. Lovicu; Q. Wang; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2784.

ARVO Annual Meeting Abstract May 2008

Fgf Promotes Activation/Expression of Components of the Wnt/Planar Cell Polarity Signaling Pathway

R. Stump; A. Nguyen; F. J. Lovicu; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2787.

ARVO Annual Meeting Abstract May 2007

Crim1 Deficiency Results in Impaired Lens and Ocular Development

F. J. Lovicu; O. Tam; J. Boros; L. Wilkinson; M. Little; J. W. McAvoy

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):2003.

ARVO Annual Meeting Abstract May 2007

Negative Regulation of FGF Signaling in the Lens by Sef

P. J. Newitt; M. L. Robinson; J. W. McAvoy; F. J. Lovicu

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):2004.

Lens March 2007

In Vitro Generation of Functional Lens-Like Structures with Relevance to Age-Related Nuclear Cataract

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Michael D. O’Connor; John W. McAvoy
TAGS: cataract, nuclear, electrophysiological studies, lens (device), lens, crystalline
Invest. Ophthalmol. Vis. Sci.. 2007; 48(3):1245-1252. https://doi.org/10.1167/iovs.06-0949

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Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation

Inhibitory roles of Sprouty and Spred on FGF-induced lens cell proliferation and fiber differentiation.

Wnt-Frizzled Signaling Is Part of an FGF-Induced Cascade that Promotes Lens Fiber Differentiation

MAPK/ERK1/2 Signaling In Tgfß-induced Lens Epithelial To Mesenchymal Transition (EMT)

WNT Signalling Pathway-Associated Proteins in Control and Keratoconus (KC) Tears and Corneas

A Role for Wnt-Frizzled Signaling During FGF-induced Fiber Differentiation

Intraflagellar Transport Protein 88 Is Required For Ciliogenesis In Lens Cells

Growth Factor Signaling in Vitreous Humor–Induced Lens Fiber Differentiation

Negative Regulation of Lens Cell Proliferation and Fiber Differentiation by Sprouty

Sprouty Prevents TGFβ-Induced Cataractogenesis

A Role for Wnt/planar Cell Polarity Signaling in Development of Lens Three-Dimensional Architecture

A Role for Sprouty 1 and 2 as Antagonists of Growth Factor Signaling in the Lens

A Role for Planar Cell Polarity (PCP) Signaling in Lens Fiber Differentiation Is Indicated by Asymmetric Localization of PCP Components

Spreds: Sprouty-Related Proteins Antagonistic for Multiple Cell Signalling Pathways Are Expressed in the Lens and Eye

Fgf Promotes Activation/Expression and Translocation of Wnt Signaling Components

Vitreous-Induced Lens Fiber Cell Differentiation: Regulation by Multiple Growth Factors via ERK1/2 and PI3-K Signaling

Fgf Promotes Activation/Expression of Components of the Wnt/Planar Cell Polarity Signaling Pathway

Crim1 Deficiency Results in Impaired Lens and Ocular Development

Negative Regulation of FGF Signaling in the Lens by Sef

In Vitro Generation of Functional Lens-Like Structures with Relevance to Age-Related Nuclear Cataract

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