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ARVO Annual Meeting Abstract June 2025

Analysis of inflammatory changes induced by mechanical stress on RPE in an animal model

Akira Minamoto; Ji-Ae Ko; Atsushige Ashimori; Fumiaki Higashijima; Kazuhiro Kimura; Yoshiaki Kiuchi; Hirokazu Sakaguchi

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):5546.

ARVO Annual Meeting Abstract June 2025

The Neuroprotective Role of IGFBP-5 in Retinal Ganglion Cells Under Oxidative Stress: Mechanisms and Therapeutic Implications

Ji-Ae Ko; Akira Minamoto; Kaori Komatsu; Kazuyuki Hirooka; Hirokazu Sakaguchi

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):6311.

ARVO Annual Meeting Abstract June 2025

Biolistic particle delivery to the cornea is well tolerated in a rabbit model

Dennis L Ko; Sangeetha Ravi Kumar; Bonnie Archer; Balamurali K Ambati; Julia A Kornfield

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3405.

ARVO Annual Meeting Abstract June 2025

Transient retinal detachment as an in vivo model for studying photoreceptor cell recovery from injury

Jingyu Yao; Mengling Yang; Lin Jia; Andrew J. Kocab; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):3819.

ARVO Annual Meeting Abstract June 2024

HIF-1α Dependent Upregulation of Angiogenic Factors by Mechanical Stimulation in Retinal Pigment Epithelial Cells

Atsushige Ashimori; Fumiaki Higashijima; Tadahiko Ogata; Ayano Sakuma; Waka Hamada; junki sunada; Ren Aoki; Masanori Mikuni; Ken’ichiro Hayashi; Makiko Wakuta; Takuya Yoshimoto; Ji-Ae Ko; Akira Minamoto; Kazuhiro Kimura

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4974.

ARVO Annual Meeting Abstract June 2024

Response to anti-VEGF antibodies in RPE to mechanical stress using animal models

Akira Minamoto; Ji-Ae Ko; Atsushige Ashimori; Fumiaki Higashijima; Kazuhiro Kimura; Yoshiaki Kiuchi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4973.

ARVO Annual Meeting Abstract June 2024

Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor

Mengling Yang; Jingyu Yao; Lin Jia; Andrew J. Kocab; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2210.

ARVO Annual Meeting Abstract June 2024

Neuroprotection of photoreceptors by combined inhibition of both Fas and autophagy pathways in P23H mice.

Jingyu Yao; Mengling Yang; Lin Jia; Andrew J. Kocab; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4755.

Retina November 2023

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

PDF

Michael J. Huvard; Jennifer L. Patnaik; David M. Kleinman; Mary Preston; David N. Zacks; Andrew J. Kocab; Jana van de Goor; Brandie D. Wagner; Steve Cho; Anne M. Lynch; Naresh Mandava
TAGS: eye, macula lutea, retinal detachment, rhegmatogenous retinal detachment, surgical procedures, operative, vision
Trans. Vis. Sci. Tech.. 2023; 12(11):35. https://doi.org/10.1167/tvst.12.11.35

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Functional Analysis of Glia Cells in RGC using coculture system

Ji-Ae Ko; Akira Minamoto; Hideaki Okumichi; Kazuyuki Hirooka; Yoshiaki Kiuchi

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1573.

ARVO Annual Meeting Abstract June 2023

Fas inhibition preserves retinal and RPE phenotype in a chronic smoke exposure model of AMD

Marisol Cano; Natalie Thornton; Andrew J. Kocab; David N Zacks; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1132.

ARVO Annual Meeting Abstract June 2023

Protective effect of pharmacological Fas inhibition in two mouse models of inherited retinal degeneration

Jingyu Yao; Mengling Yang; Lin Jia; Andrew J. Kocab; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1540.

ARVO Annual Meeting Abstract June 2023

Safety and tolerability of intravitreal ONL1204 in patients with macula-off rhegmatogenous retinal detachment

Matthew P Simunovic; Lindsay Puscas; Sushanta Mallick; Andrew J. Kocab; David Maxwell Kleinman; David N Zacks

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2491.

ARVO Annual Meeting Abstract June 2022

Risuteganib-directed staining localizes in the Retinal Pigment Epithelium of Retinal Tissue from Aged, but not Young, Mice

Jin Mo Koo; Connor Call; Dan Zhou; John Park; Hampar Karageozian; Vicken H Karageozian; Zixuan Shao; Julia A. Kornfield

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4414 – F0093.

ARVO Annual Meeting Abstract June 2022

The Minipig as a Model for Intravitreal Injection: Evaluation of a Time Course of Ocular Findings with a Repeated Injection

William Brock; Andrew J. Kocab

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):666 – F0120.

Genetics November 2021

ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers

PDF

Sahar Gelfman; Dominique Monnet; Ann J. Ligocki; Thierry Tabary; Arden Moscati; Xiaodong Bai; Jan Freudenberg; Blerta Cooper; Jack A. Kosmicki; Sarah Wolf; Manuel A. R. Ferreira; John Overton; Jonathan Weyne; Eli A. Stahl; Aris Baras; Carmelo Romano; Jacques H. M. Cohen; Giovanni Coppola; Antoine Brézin; for the Regeneron Genetics Center
TAGS: alleles, human leukocyte antigens, vitiliginous chorioretinitis
Invest. Ophthalmol. Vis. Sci.. 2021; 62(14):3. https://doi.org/10.1167/iovs.62.14.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Suppression of Murine Choroidal and Retinal Neovascularization by Risuteganib and the Accompanying Transcriptome Changes in the OIR Retina

Zixuan Shao; Sean F. Hackett; Raquel Formica; Yogita Kanan; Dan Zhou; John Y Park; Hampar L Karageozian; Vicken H Karageozian; Peter A Campochiaro; Julia A. Kornfield

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):186.

ARVO Annual Meeting Abstract June 2021

Mouse breeding strategies for successful preclinical studies

Seyedeh Zeinab Mirjalili Mohanna; Andrea J Korecki; Elizabeth M Simpson

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1465.

ARVO Annual Meeting Abstract June 2020

Safety and Efficacy of Risuteganib in Intermediate Non-exudative Age-Related Macular Degeneration

Raj Maturi; Glenn J Jaffe; Justis P Ehlers; Peter K Kaiser; David S Boyer; Jeffrey S Heier; Julia A Kornfield; Baruch D Kuppermann; Hugo Quiroz-Mercado; Janine Aubel; Lisa Karageozian; Vicken H Karageozian; Melvin Sarayba

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1944.

ARVO Annual Meeting Abstract June 2020

Mechanism of Action of Risuteganib for Retinal Diseases through Protection of Retinal Pigment Epithelium (RPE) and Enhancement of Mitochondrial Functions

Dan Zhou; Marilyn Chwa; Zixuan Shao; Jin Mo Koo; John Y Park; Hampar L Karageozian; Vicken H Karageozian; Cristina M Kenney; Julia A Kornfield

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4949.

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Analysis of inflammatory changes induced by mechanical stress on RPE in an animal model

The Neuroprotective Role of IGFBP-5 in Retinal Ganglion Cells Under Oxidative Stress: Mechanisms and Therapeutic Implications

Biolistic particle delivery to the cornea is well tolerated in a rabbit model

Transient retinal detachment as an in vivo model for studying photoreceptor cell recovery from injury

HIF-1α Dependent Upregulation of Angiogenic Factors by Mechanical Stimulation in Retinal Pigment Epithelial Cells

Response to anti-VEGF antibodies in RPE to mechanical stress using animal models

Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor

Neuroprotection of photoreceptors by combined inhibition of both Fas and autophagy pathways in P23H mice.

An Evaluation of the Repeatability of Visual Function Following Surgical Repair of Macula-Off Rhegmatogenous Retinal Detachment

Functional Analysis of Glia Cells in RGC using coculture system

Fas inhibition preserves retinal and RPE phenotype in a chronic smoke exposure model of AMD

Protective effect of pharmacological Fas inhibition in two mouse models of inherited retinal degeneration

Safety and tolerability of intravitreal ONL1204 in patients with macula-off rhegmatogenous retinal detachment

Risuteganib-directed staining localizes in the Retinal Pigment Epithelium of Retinal Tissue from Aged, but not Young, Mice

The Minipig as a Model for Intravitreal Injection: Evaluation of a Time Course of Ocular Findings with a Repeated Injection

ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers

Suppression of Murine Choroidal and Retinal Neovascularization by Risuteganib and the Accompanying Transcriptome Changes in the OIR Retina

Mouse breeding strategies for successful preclinical studies

Safety and Efficacy of Risuteganib in Intermediate Non-exudative Age-Related Macular Degeneration

Mechanism of Action of Risuteganib for Retinal Diseases through Protection of Retinal Pigment Epithelium (RPE) and Enhancement of Mitochondrial Functions

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