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ARVO Annual Meeting Abstract June 2022

A novel non-retinoid visual cycle inhibitor RPE65-61 protects the retinal photoreceptors from light-induced degeneration

Gennadiy P Moiseyev; Yuhong Wang; Xiang Ma; Parthasarathy Muthuraman; Arun Raja; Aravindan Jayaraman; Konstantin Petrukhin; Christopher Cioffi; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1773 – F0322. doi:

ARVO Annual Meeting Abstract June 2022

PNPLA2 mobilizes retinyl esters from retinosomes in the retinal pigment epithelium

Miwa Hara; Wenjing Wu; Yusuke Takahashi; Jian-Xing Ma; Gennadiy P Moiseyev

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2483 – F0190. doi:

ARVO Annual Meeting Abstract June 2022

Monocarboxylate transporters: Role and Regulation in Corneal Diabetes

Pawan Shrestha; Amy Whelchel; Sarah E Nicholas; Dimitrios Karamichos; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3650 – A0215. doi:

ARVO Annual Meeting Abstract June 2022

The regulation of cGAS-STING signaling by PPARα-mediated autophagy in ischemic retinopathy

Xiang Ma; Yusuke Takahashi; Jiyang Cai; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4601 – F0393. doi:

ARVO Annual Meeting Abstract June 2022

The interplay of luminance and genetics in the retinopathy induced by the dominant RPE65 mutation

Wenjing Wu; Yusuke Takahashi; Xiang Ma; Gennadiy P Moiseyev; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):460. doi:

ARVO Annual Meeting Abstract June 2022

Wnt Signaling Regulates Cornea Wound Healing

Wentao Liang; Jian-Xing Ma

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1121. doi:

Articles August 2020

Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation

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Yan Shao; Jianglei Chen; Xiao-Rong Li; Jian-Xing Ma
TAGS: bromodeoxyuridine, retinal neovascularization, mice, retina
Trans. Vis. Sci. Tech.. 2020; 9(9):4. doi: https://doi.org/10.1167/tvst.9.9.4

ARVO Annual Meeting Abstract June 2020

Dysregulation of Wnt signaling promotes the sub-retinal fibrosis in neovascular age-related macular degeneration (nAMD)

Xiang Ma; Rui Cheng; Yusuke Takahashi; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3682. doi:

ARVO Annual Meeting Abstract June 2020

Old Dog New Trick: Detection and Quantification of Retinal Neovascularization using BrdU Incorporation

Yan shao; Jianglei Chen; Xiaorong Li; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):181. doi:

Retina April 2020

PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis

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Sihao Ye; Qian Chen; Nan Jiang; Xu Liang; Jingming Li; Rongrong Zong; Caihong Huang; Yan Qiu; Jian-Xing Ma; Zuguo Liu
TAGS: fibrosis, neovascularization, pathologic, ppar alpha, retina, retinal neovascularization, proteins, inflammation, western blotting, gliosis, mice
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):15. doi: https://doi.org/10.1167/iovs.61.4.15

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

Gennadiy P Moiseyev; Volha Malechka; Rui Cheng; Jianglei Chen; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2659. doi:

ARVO Annual Meeting Abstract July 2019

Ligand Specificities of Wnt Co-receptors in Wnt Signaling Regulation

Yusuke Takahashi; Harminder Singh; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2664. doi:

ARVO Annual Meeting Abstract July 2019

Elucidating the role of peroxisome proliferator-activated receptor alpha in diabetic keratopathy using novel in vivo and in vitro models

Amy Whelchel; Greg Matlock; Jian-Xing (Jay) Ma; Dimitrios Karamichos

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3234. doi:

ARVO Annual Meeting Abstract July 2019

Targeting PEDF for the treatment of experimental autoimmune uveitis

Xiaomin Zhang; Zhihui Zhang; Shuang Chen; Nu Chen; Jian-Xing (Jay) Ma; Xiaorong Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):794. doi:

ARVO Annual Meeting Abstract July 2019

Diabetes-induced down-regulation of PPARα plays a key role in the deficiency of endothelial progenitor cells and mitochondrial function

yan shao; Jianglei Chen; Xiaorong Li; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6425. doi:

ARVO Annual Meeting Abstract July 2019

Fenofibrate-loaded biodegradable nanoparticles for treating retinal neovascularization

Qingguo Xu; Fangfang Qiu; Qian Chen; Kelu Zhou; Yan Shao; Greg Matlock; Xiang Ma; Wenjing Wu; Tuo Meng; Yanhong Du; Xiang Wang; Guotao Deng; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6393. doi:

Cornea July 2018

Therapeutic Effects of a Novel Phenylphthalimide Analog for Corneal Neovascularization and Retinal Vascular Leakage

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Bing Wang; Pui-Kai Li; Jian-xing Ma; Danyang Chen
TAGS: angiogenesis inhibitors, cornea, corneal neovascularization, diabetes mellitus, rats, retina, streptozocin, thalidomide, vascular endothelial growth factor a, alkalies
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3630-3642. doi: https://doi.org/10.1167/iovs.18-24015

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

PPARalpha is required for RPE metabolism and function

Rui Cheng; Kelu Zhou; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1184. doi:

ARVO Annual Meeting Abstract July 2018

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Gennadiy P Moiseyev; Younghwa Shin; Yusuke Takahashi; Konstantin Petrukhin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5330. doi:

ARVO Annual Meeting Abstract July 2018

Distinct Roles of Wnt Co-receptors in the Regulation of Wnt Signaling in Diabetic Retinopathy

Yusuke Takahashi; Harminder Singh; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5371. doi:

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A novel non-retinoid visual cycle inhibitor RPE65-61 protects the retinal photoreceptors from light-induced degeneration

PNPLA2 mobilizes retinyl esters from retinosomes in the retinal pigment epithelium

Monocarboxylate transporters: Role and Regulation in Corneal Diabetes

The regulation of cGAS-STING signaling by PPARα-mediated autophagy in ischemic retinopathy

The interplay of luminance and genetics in the retinopathy induced by the dominant RPE65 mutation

Wnt Signaling Regulates Cornea Wound Healing

Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation

Dysregulation of Wnt signaling promotes the sub-retinal fibrosis in neovascular age-related macular degeneration (nAMD)

Old Dog New Trick: Detection and Quantification of Retinal Neovascularization using BrdU Incorporation

PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

Ligand Specificities of Wnt Co-receptors in Wnt Signaling Regulation

Elucidating the role of peroxisome proliferator-activated receptor alpha in diabetic keratopathy using novel in vivo and in vitro models

Targeting PEDF for the treatment of experimental autoimmune uveitis

Diabetes-induced down-regulation of PPARα plays a key role in the deficiency of endothelial progenitor cells and mitochondrial function

Fenofibrate-loaded biodegradable nanoparticles for treating retinal neovascularization

Therapeutic Effects of a Novel Phenylphthalimide Analog for Corneal Neovascularization and Retinal Vascular Leakage

PPARalpha is required for RPE metabolism and function

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Distinct Roles of Wnt Co-receptors in the Regulation of Wnt Signaling in Diabetic Retinopathy

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