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Articles October 2020

The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

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David G. Birch; Peiyao Cheng; Jacque L. Duncan; Allison R. Ayala; Maureen G. Maguire; Isabelle Audo; Janet K. Cheetham; Todd A. Durham; Abigail T. Fahim; Frederick L. Ferris, III; Elise Heon; Rachel M. Huckfeldt; Alessandro Iannaccone; Naheed W. Khan; Eleonora M. Lad; Michel Michaelides; Mark E. Pennesi; Katarina Stingl; Ajoy Vincent; Christina Y. Weng; for the Foundation Fighting Blindness Consortium Investigator Group
TAGS: electroretinography, visual acuity
Trans. Vis. Sci. Tech.. 2020; 9(11):9. doi: https://doi.org/10.1167/tvst.9.11.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Photoreceptor imaging in USH2A -related non-syndromic retinitis pigmentosa and Usher Syndrome type 2A patients

Lesley Everett; Jessica Wong; Jenna Cava; Travis Proco; Austin Roorda; Joseph Carroll; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):209. doi:

ARVO Annual Meeting Abstract June 2020

Multimodal imaging in patients with MYO7A- related Usher syndrome

Leslie Small; Jessica Wong; Mark E Pennesi; Hao Zhou; Ruikang K Wang; Abhishek Chadha; David S Williams; Austin Roorda; Travis Proco; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):228. doi:

ARVO Annual Meeting Abstract June 2020

RUSH2A: systematic cohort variant modeling reveals phenotypic correlates

Robert B. Hufnagel; Bin Guan; Ehsan Ullah; Wendi Liang; Carmen Brewer; Stephen P Daiger; Kari E Branham; Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):836. doi:

ARVO Annual Meeting Abstract June 2020

Accelerating research in rare inherited retinal disorders (IRDs) through an international consortium

Janet K Cheetham; Allison Ayala; David G Birch; Jacque L Duncan; Todd Durham; Frederick L Ferris; Maureen Maguire; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3356. doi:

ARVO Annual Meeting Abstract June 2020

Baseline visual fields in the RUSH2A study: Associated factors and correlation with measures of disease severity

Jacque L Duncan; Wendi Liang; Isabelle S Audo; David G Birch; Joseph Carroll; Janet K. Cheetham; Laura R Erker; Frederick L Ferris; Elise Heon; Robert Hufnagel; Alessandro Iannaccone; Glenn J Jaffe; Christine N Kay; Maureen Maguire; Michel Michaelides; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3364. doi:

ARVO Annual Meeting Abstract June 2020

Natural history study of visual function in patients with BBS1 and BBS10 -related Bardet-Biedl syndrome.

Monika Grudzinska Pechhacker; Samuel G Jacobson; Ine Strubbe; Jacque L Duncan; Arlene V Drack; Andrea L Vincent; Tomas Aleman; Caroline Van Cauwenbergh; Elfride De Baere; Helene Dollfus; Nathalie Goetz; Bart Peter Leroy; Ajoy Vincent; Elise Heon

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4463. doi:

ARVO Annual Meeting Abstract June 2020

Test-retest variability of static perimetry and microperimetry results from the RUSH2A study

Allison Ayala; Wendi Liang; David G Birch; Janet K Cheetham; Elvira N Chegarnov; Jacque L Duncan; Todd Durham; Frederick L Ferris; Eleonora M Lad; Maureen Maguire; Mark E Pennesi

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3342. doi:

ARVO Annual Meeting Abstract June 2020

Meta-learning approach to automatically register multivendor retinal images

Ali Hasan; Zengtian Deng; Jessica Loo; Dibyendu Mukherjee; Jacque L Duncan; David G Birch; Glenn J Jaffe; Sina Farsiu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1634. doi:

ARVO Annual Meeting Abstract June 2020

Creating an in vitro Leber congenital amaurosis model to investigate disease mechanisms

Kathleen R Chirco; Shereen Chew; Jacque L Duncan; Anthony Moore; Deepak A Lamba

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3803. doi:

ARVO Annual Meeting Abstract June 2020

Deep learning-based automatic segmentation of intact ellipsoid zone area on optical coherence tomography images of USH2A-related retinal degeneration

Sina Farsiu; Jessica Loo; Jacque L Duncan; David G Birch; Glenn J Jaffe

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):485. doi:

Articles June 2020

OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker

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Khashayar Nattagh; Hao Zhou; Nicholas Rinella; Qinqin Zhang; Yining Dai; Katharina G. Foote; Cathrine Keiner; Michael Deiner; Jacque L. Duncan; Travis C. Porco; Ruikang K. Wang; Daniel M. Schwartz
TAGS: angiogram, atrophy, biological markers, chief complaint, fluid flow
Trans. Vis. Sci. Tech.. 2020; 9(7):6. doi: https://doi.org/10.1167/tvst.9.7.6

Review June 2020

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

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Debra A. Thompson; Alessandro Iannaccone; Robin R. Ali; Vadim Y. Arshavsky; Isabelle Audo; James W. B. Bainbridge; Cagri G. Besirli; David G. Birch; Kari E. Branham; Artur V. Cideciyan; Steven P. Daiger; Deniz Dalkara; Jacque L. Duncan; Abigail T. Fahim; John G. Flannery; Roberto Gattegna; John R. Heckenlively; Elise Heon; K. Thiran Jayasundera; Naheed W. Khan; Henry Klassen; Bart P. Leroy; Robert S. Molday; David C. Musch; Mark E. Pennesi; Simon M. Petersen-Jones; Eric A. Pierce; Rajesh C. Rao; Thomas A. Reh; Jose A. Sahel; Dror Sharon; Paul A. Sieving; Enrica Strettoi; Paul Yang; David N. Zacks; The Monaciano Consortium
TAGS: outcome measures, retinal diseases, surrogate endpoints, genetics, vision, natural history, ethics, gene therapy
Trans. Vis. Sci. Tech.. 2020; 9(7):2. doi: https://doi.org/10.1167/tvst.9.7.2

Retina April 2020

Comparing Cone Structure and Function in RHO- and RPGR- Associated Retinitis Pigmentosa

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Katharina G. Foote; Jessica J. Wong; Alexandra E. Boehm; Ethan Bensinger; Travis C. Porco; Austin Roorda; Jacque L. Duncan
TAGS: mutation, retinal cone, retinitis pigmentosa
Invest. Ophthalmol. Vis. Sci.. 2020; 61(4):42. doi: https://doi.org/10.1167/iovs.61.4.42

Perspective February 2020

Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

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Ian M. MacDonald; Christopher Moen; Jacque L. Duncan; Stephen H. Tsang; Jasmina Cehajic-Kapetanovic; Tomas S. Aleman
TAGS: choroideremia, gene therapy, retinal degeneration, spatial vectors
Trans. Vis. Sci. Tech.. 2020; 9(3):17. doi: https://doi.org/10.1167/tvst.9.3.17

Retina November 2019

Cone Structure Persists Beyond Margins of Short-Wavelength Autofluorescence in Choroideremia

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Katharina G. Foote; Nicholas Rinella; Janette Tang; Nicolas Bensaid; Hao Zhou; Qinqin Zhang; Ruikang K. Wang; Travis C. Porco; Austin Roorda; Jacque L. Duncan
TAGS: autofluorescence, chief complaint, choroideremia, diagnostic imaging, photoreceptors, retinal cone, perfusion
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4931-4942. doi: https://doi.org/10.1167/iovs.19-27979

Retina July 2019

Loss of Foveal Cone Structure Precedes Loss of Visual Acuity in Patients With Rod-Cone Degeneration

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Ethan Bensinger; Nicholas Rinella; Asma Saud; Panagiota Loumou; Kavitha Ratnam; Shane Griffin; Jia Qin; Travis C. Porco; Austin Roorda; Jacque L. Duncan
TAGS: blindness, retinal cone, retinitis pigmentosa, tissue degeneration, rod photoreceptors, visual acuity, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):3187-3196. doi: https://doi.org/10.1167/iovs.18-26245

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Gene therapy trials for hereditary retinal degenerations

Jacque L Duncan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):992. doi:

ARVO Annual Meeting Abstract July 2019

Structure and Function of Dysflective Cones in Healthy and Diseased Eyes

Ethan Bensinger; Katharina G Foote; Jessica J. Wong; Jacque L Duncan; Austin Roorda

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1031. doi:

ARVO Annual Meeting Abstract July 2019

Multiple copies of rhodopsin as a novel cause of autosomal dominant retinitis pigmentosa

Jacque L Duncan; Karmen Trzupek; Joan Fisher; Leilla Kenney; Sari Tuupanen; Miika Mehine; Stephen P Daiger; Brian Mansfield

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2943. doi:

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The RUSH2A Study: Best-Corrected Visual Acuity, Full-Field Electroretinography Amplitudes, and Full-Field Stimulus Thresholds at Baseline

Photoreceptor imaging in USH2A -related non-syndromic retinitis pigmentosa and Usher Syndrome type 2A patients

Multimodal imaging in patients with MYO7A- related Usher syndrome

RUSH2A: systematic cohort variant modeling reveals phenotypic correlates

Accelerating research in rare inherited retinal disorders (IRDs) through an international consortium

Baseline visual fields in the RUSH2A study: Associated factors and correlation with measures of disease severity

Natural history study of visual function in patients with BBS1 and BBS10 -related Bardet-Biedl syndrome.

Test-retest variability of static perimetry and microperimetry results from the RUSH2A study

Meta-learning approach to automatically register multivendor retinal images

Creating an in vitro Leber congenital amaurosis model to investigate disease mechanisms

Deep learning-based automatic segmentation of intact ellipsoid zone area on optical coherence tomography images of USH2A-related retinal degeneration

OCT Angiography to Predict Geographic Atrophy Progression using Choriocapillaris Flow Void as a Biomarker

Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium

Comparing Cone Structure and Function in RHO- and RPGR- Associated Retinitis Pigmentosa

Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

Cone Structure Persists Beyond Margins of Short-Wavelength Autofluorescence in Choroideremia

Loss of Foveal Cone Structure Precedes Loss of Visual Acuity in Patients With Rod-Cone Degeneration

Gene therapy trials for hereditary retinal degenerations

Structure and Function of Dysflective Cones in Healthy and Diseased Eyes

Multiple copies of rhodopsin as a novel cause of autosomal dominant retinitis pigmentosa

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