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Articles January 2019

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

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Susan S. Lee; Alexandra Almazan; Sherri Decker; Yan Zhong; Alazar N. Ghebremeskel; Patrick Hughes; Michael R. Robinson; James A. Burke; Robert N. Weinreb
TAGS: intraocular pressure, pharmacokinetics, bimatoprost
Trans. Vis. Sci. Tech.. 2019; 8(1):15. doi: 10.1167/tvst.8.1.15

Retina December 2018

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

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Gerard A. Rodrigues; Matthew Mason; Lori-Ann Christie; Candice Hansen; Lisa M. Hernandez; James Burke; Keith A. Luhrs; Thomas C. Hohman
TAGS: angiogenesis, vascular endothelial growth factor a, oryctolagus cuniculus, bevacizumab, ranibizumab, affinity, aflibercept, anti-vascular endothelial growth factor therapy, vascular permeability
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5836-5846. doi: 10.1167/iovs.18-25307

ARVO Annual Meeting Abstract July 2018

Comparison of Retinal Microvasculature and Neurodegenerative Changes among Alzheimer’s disease, Mild Cognitive Impairment, and Controls

Stephen Paul Yoon; Dilraj Singh Grewal; Bryce W Polascik; Cynthia Dunn; Kim Johnson; James Burke; Sharon Fekrat

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2818. doi:

ARVO Annual Meeting Abstract July 2018

In Vitro and In Vivo Characterization of Abicipar Pegol, an anti-VEGF DARPin® Therapeutic

Gerry A Rodrigues; Matthew Mason; Lori-Ann Christie; Candice Hansen; James A Burke; Keith Luhrs; Thomas C Hohman

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):233. doi:

ARVO Annual Meeting Abstract July 2018

Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) Enhances Spatial Sweep Visual Evoked Potential (sVEP) in a Non-human Primate Model of Chronic Glaucoma

James A Burke; Kai-Ming Zhang; Werhner Orilla; Corine Ghosn; Larry A Wheeler

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1246. doi:

ARVO Annual Meeting Abstract July 2018

Visualization of conjunctival lymphatic vessels in normotensive rabbits

Lakshmi Rajagopalan; Saumya Nagar; Werhner Orilla; Karl G Csaky; Alexandra Almazan; James A Burke; Michael R Robinson; Susan S Lee

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1654. doi:

ARVO Annual Meeting Abstract July 2018

A Rabbit Model for Glaucoma Filtration Surgery

Saumya Nagar; Alexandra Almazan; Lakshmi Rajagopalan; Susan S Lee; Werhner Orilla; James A Burke; Michael R Robinson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):492. doi:

ARVO Annual Meeting Abstract July 2018

fMRI shows Functional Recovery by Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) in a Rabbit Model of Retinal Ganglion Cell (RGC) Degeneration

Corine Ghosn; James A Burke

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6127. doi:

ARVO Annual Meeting Abstract July 2018

In Vivo Angiographic Study of Rabbit Aqueous Outflow following Ab Interno Gelatin Stent Implantation

Susan S Lee; Saumya Nagar; Lakshmi Rajagopalan; Werhner Orilla; Karl G Csaky; Alex Huang; Alexandra Almazan; James A Burke; Michael R Robinson

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1653. doi:

ARVO Annual Meeting Abstract June 2017

In Vivo Angiographic Study of Normal Rabbit Aqueous Outflow

Susan S Lee; Alexandra Almazan; James A Burke; Michael R Robinson

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1078. doi:

ARVO Annual Meeting Abstract June 2017

Interspecies Comparison of Small Molecule Distribution Into the Anterior Chamber Following Intravitreal Administration

Jennifer Seal; Werhner Orilla; Edward Chow; James A Burke; Jie Shen

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):439. doi:

ARVO Annual Meeting Abstract June 2017

Brimonidine drug delivery system (Brimo DDS Generation 1) slows the growth of retinal pigment epithelial hypofluorescence following regional blue light irradiation in a nonhuman primate (NHP) model of geographic atrophy (GA)

Corine Ghosn; Alexandra Almazan; Sherri Decker; James A Burke

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1960. doi:

ARVO Annual Meeting Abstract September 2016

Retinal Biomarkers of Alzheimer’s Disease

Heather Whitson; Sina Farsiu; Sandra S Stinnett; Leon Kwark; Guy Potter; James Burke; Scott W Cousins; Eleonora M Lad

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3372. doi:

ARVO Annual Meeting Abstract September 2016

The Effect of Betadine on Vision.

Caren Oquindo; William H Ridder; Kavita Dhamdhere; James A Burke

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3854. doi:

ARVO Annual Meeting Abstract September 2016

The Effect of Betadine on Vision and on Cornea in Rabbits

Kavita Dhamdhere; Alexandra S P Almazan; Michael Engles; James A Burke

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3855. doi:

ARVO Annual Meeting Abstract September 2016

Additive ocular hypotensive effects of Bimatoprost Sustained-Release intracameral implant on potent topical therapy in monkeys

Susan S Lee; Alexandra S P Almazan; Huajiang Li; Alazar N Ghebremeskel; Patrick M Hughes; Michael R Robinson; James A Burke

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3006. doi:

ARVO Annual Meeting Abstract September 2016

Intracameral Administration of a Sustained Release Bimatoprost Implant Efficiently Delivers Bimatoprost to Target Tissue Reducing Risk of Topical Prostaglandin Analog- Associated Adverse Events

Jennifer Seal; Shamira Perera; Michael Coote; Michael R Robinson; Patrick M Hughes; Alazar N Ghebremeskel; James A Burke; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3022. doi:

ARVO Annual Meeting Abstract June 2015

Retinal imaging biomarkers for early diagnosis of Alzheimer’s disease

Heather E Whitson; Sina Farsiu; Sandra Stinnett; Sung Lee; Leon Kwark; Guy Potter; James Burke; Scott W Cousins; Eleonora Lad

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):389. doi:

ARVO Annual Meeting Abstract June 2015

Comparison of Psychophysical and Electrophysiological Acuity Measurements in Non-Human Primates (NHPs).

William H Ridder; Kai-Ming Zhang; James A Burke

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4310. doi:

ARVO Annual Meeting Abstract April 2014

Exploring Drug Distribution via the Suprachoroidal Space in a Human and Rabbit Eye Using Computational Modeling

Julie Elizabeth Whitcomb; Mohammad R Kazemi; James A Burke; Mayssa Attar

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5250. doi:

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Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost

Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability

Comparison of Retinal Microvasculature and Neurodegenerative Changes among Alzheimer’s disease, Mild Cognitive Impairment, and Controls

In Vitro and In Vivo Characterization of Abicipar Pegol, an anti-VEGF DARPin® Therapeutic

Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) Enhances Spatial Sweep Visual Evoked Potential (sVEP) in a Non-human Primate Model of Chronic Glaucoma

Visualization of conjunctival lymphatic vessels in normotensive rabbits

A Rabbit Model for Glaucoma Filtration Surgery

fMRI shows Functional Recovery by Intravitreal Brimonidine Drug Delivery System (Brimo DDS Generation 1) in a Rabbit Model of Retinal Ganglion Cell (RGC) Degeneration

In Vivo Angiographic Study of Rabbit Aqueous Outflow following Ab Interno Gelatin Stent Implantation

In Vivo Angiographic Study of Normal Rabbit Aqueous Outflow

Interspecies Comparison of Small Molecule Distribution Into the Anterior Chamber Following Intravitreal Administration

Brimonidine drug delivery system (Brimo DDS Generation 1) slows the growth of retinal pigment epithelial hypofluorescence following regional blue light irradiation in a nonhuman primate (NHP) model of geographic atrophy (GA)

Retinal Biomarkers of Alzheimer’s Disease

The Effect of Betadine on Vision.

The Effect of Betadine on Vision and on Cornea in Rabbits

Additive ocular hypotensive effects of Bimatoprost Sustained-Release intracameral implant on potent topical therapy in monkeys

Intracameral Administration of a Sustained Release Bimatoprost Implant Efficiently Delivers Bimatoprost to Target Tissue Reducing Risk of Topical Prostaglandin Analog- Associated Adverse Events

Retinal imaging biomarkers for early diagnosis of Alzheimer’s disease

Comparison of Psychophysical and Electrophysiological Acuity Measurements in Non-Human Primates (NHPs).

Exploring Drug Distribution via the Suprachoroidal Space in a Human and Rabbit Eye Using Computational Modeling

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