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ARVO Annual Meeting Abstract June 2021

Rho 1-2 meganuclease, an allele-specific gene-editing therapy, rejuvenates rod photoreceptor structure and function in a pig model of autosomal dominant Retinitis Pigmentosa (adRP).

archana jalligampala; Jennifer Noel; James W Fransen; Wei Wang; Maha Jabbar; Nazarul Hasan; Gobinda Pangeni; Bhubanananda Sahu; Whitney Lewis; Jeff Smith; Victor Bartsevich; Kristi Viles; Derek Jantz; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1478. doi:

ARVO Annual Meeting Abstract June 2021

Allele-selective reduction of P23H-mutant rhodopsin with stereopure oligonucleotides rescues phenotype associated with retinitis pigmentosa in preclinical models

Michael Byrne; Vinod Vathipadickal; Lankai Guo; Yuan Yin; Hailin Yang; Richard Looby; Lauren Norwood; James W Fransen; archana jalligampala; Jennifer Noel; Chandra Vargeese; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):185. doi:

ARVO Annual Meeting Abstract June 2020

Stereopure oligonucleotides achieve allele-selective reduction of P23H mutant rhodopsin

Vinod Vathipadiekal; Lankai Guo; Yuan Yin; Qiong Shen; Hailin Yang; Richard Looby; Lauren Norwood; James Fransen; archana jalligampala; Jennifer Noel; Chandra Vargeese; Maureen A McCall; Michael Byrne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1912. doi:

ARVO Annual Meeting Abstract June 2020

An Allele-Independent Gene Therapy Strategy Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

archana jalligampala; James Fransen; Jennifer Noel; Gobinda Pangeni; Maha Haleem Jabbar; William W Hauswirth; Alfred S Lewin; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4484. doi:

ARVO Annual Meeting Abstract June 2020

Allele-specific Homing Endonuclease (HE) Gene Editing Induces Rod Function in a P23H Transgenic Swine Model of Retinitis Pigmentosa

James W Fransen; archana jalligampala; Jennifer Noel; Wei Wang; Jeff Smith; Victor Bartsevich; Kristi Viles; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1915. doi:

ARVO Annual Meeting Abstract June 2015

Parallel OFF bipolar cell pathways develop and function in the absence of dendritic kainate receptors

Sarah A Minton; James W Fransen; Susumu Tomita; Jonathan B Demb; Bart Gerard Borghuis

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1336. doi:

ARVO Annual Meeting Abstract June 2015

Slow Onset and Protracted Decline in Visual Function in the P23H Rhodopsin Knockin Mouse Model of Retinitis Pigmentosa

Gobinda Pangeni; James W Fransen; Ian Scott Pyle; Maureen A McCall; Visual Neuroscience

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4260. doi:

ARVO Annual Meeting Abstract June 2015

A temporal gradient of excitatory input contributes to direction selectivity in the dendrites of OFF starburst amacrine cells

Bart Gerard Borghuis; James W Fransen

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2613. doi:

Retina April 2014

Cone Photoreceptors Develop Normally in the Absence of Functional Rod Photoreceptors in a Transgenic Swine Model of Retinitis Pigmentosa

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Juan P. Fernandez de Castro; Patrick A. Scott; James W. Fransen; James Demas; Paul J. DeMarco; Henry J. Kaplan; Maureen A. McCall
TAGS: animals, transgenic, electroretinography, retinal cone, retinitis pigmentosa, rod photoreceptors, suidae
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2460-2468. doi: https://doi.org/10.1167/iovs.13-13724

ARVO Annual Meeting Abstract June 2013

Changes in retinal ganglion cell activity in the P23H mini-swine model of retinal degeneration

Juan Fernandez de Castro; James Demas; James Fransen; Paul DeMarco; Henry Kaplan; Maureen McCall

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3386. doi:

ARVO Annual Meeting Abstract June 2013

Immunohistochemical and electrophysiological analysis of rat retinas after subretinal implantation of photovoltaic arrays

Jacob Light; James Fransen; Alice Adkins; Gobinda Pangeni; James Loudin; Keith Mathieson; Daniel Palanker; Maureen McCall; Machelle Pardue

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1034. doi:

ARVO Annual Meeting Abstract June 2013

Responses evoked by monopolar and bipolar photovoltaic arrays in the S334ter-3 rat model of retinitis pigmentosa

James Fransen; Gobinda Pangeni; Benjamin James; James Loudin; Keith Mathieson; Theodore Kamins; James Harris; Daniel Palanker; Machelle Pardue; Maureen McCall

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):1050. doi:

ARVO Annual Meeting Abstract March 2012

Subretinal Implantation of Microphotodiode Arrays: In vivo Assessment of Threshold and Spatial Activation

James W. Fransen; Moon K. Kim; Alice Adkins; James Loudin; Machelle T. Pardue; Daniel V. Palanker; Maureen A. McCall

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5529. doi:

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