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Editorial December 2018

Foreword: Dry Age-Related Macular Degeneration

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Milam A. Brantley, Jr; James T. Handa
TAGS: age-related macular degeneration
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMDi-AMDi. doi: 10.1167/iovs.18-26218

Special Issue July 2018

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

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Sayan Ghosh; Peng Shang; Hiroto Terasaki; Nadezda Stepicheva; Stacey Hose; Meysam Yazdankhah; Joseph Weiss; Taiji Sakamoto; Imran A. Bhutto; Shuli Xia; J. Samuel Zigler, Jr; Ram Kannan; Jiang Qian; James T. Handa; Debasish Sinha
TAGS: crystallins, age-related macular degeneration, epithelial to mesenchymal transition, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD104-AMD113. doi: 10.1167/iovs.18-24132

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

P2X7R inhibition activates autophagy and impairs the inflammasome response in the RPE

James T Handa; Hanna Eilken; Charles Eberhart; Marcus Karlstetter; Hartmut Schirok; Meysam Yazdankhah; Peng Shang; Marisol del Valle Cano; Jeff S Mumm; Alexander Zink; Carsten Terjung; Bernd Kalthof; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):64. doi:

ARVO Annual Meeting Abstract July 2018

Visual Cycle Proteins Increase Acutely After Stimulation with CSE

Marisol del Valle Cano; Roma Pegany; Joshua Ocasio; Audrey Collins; Sayantan Datta; Lei Wang; tongyun Liu; Sonny Dike; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):342. doi:

ARVO Annual Meeting Abstract July 2018

Long-term visual and anatomical outcomes in treatment naïve neovascular age-related macular degeneration (nAMD) patients treated with anti-VEGF agents

Saleema A. Kherani; Roomasa Channa; Rimsha Shaukat; Olukemi Adeyemo; Mustafa Iftikhar; Adrienne Scott; Akrit Sodhi; James T Handa; Ingrid Zimmer-Galler; Adam Wenick; Sharon D Solomon; Mira Sachdeva; Catherine B Meyerle; Peter A Campochiaro

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):825. doi:

ARVO Annual Meeting Abstract July 2018

The Diagnostic Utility of Ultrasound in the Management of Severe Corneal Ulcers and Non-infectious Corneal Melt

Narine Viruni; Tin Yan Alvin Liu; Sarah Wang; Alice Yang Zhang; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4672. doi:

ARVO Annual Meeting Abstract July 2018

Pink1 and Nrf2 mediated mitochondrial retrograde signaling in RPE heterogeneity

Sayantan Datta; Marisol del Valle Cano; tongyun Liu; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1187. doi:

ARVO Annual Meeting Abstract July 2018

Identification of endpoints appropriate in evaluating potential therapeutics for retinal degenerations using apoB100 transgenic mice.

Mayur Choudhary; Faryan Tayyari; James T Handa; Goldis Malek

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2442. doi:

ARVO Annual Meeting Abstract July 2018

αB-crystallin is active in Signaling, Autophagy, and Apoptosis in Ocular Melanoma

Gregory Konar; Peng Shang; Subrata Mishra; Sayan Ghosh; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3169. doi:

ARVO Annual Meeting Abstract June 2017

Visual and anatomical outcomes in NVAMD patients with subfoveal hemorrhage (SFH) treated with anti-VEGF agents

Saleema Kherani; Adrienne W. Scott; Adam Wenick; Ingrid E Zimmer-Galler; Christopher Brady; Akrit Sodhi; Catherine Meyerele; Rimsha Shaukat; Olukemi Adeyemo; Roomasa Channa; James T Handa; Tahreem Aman Mir; Peter A Campochiaro

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):415. doi:

ARVO Annual Meeting Abstract June 2017

Pink1 deficiency induces Nrf2 dependent EMT and metabolic dysfunction in RPE cells

Sayantan Datta; Marisol del Valle Cano; Kie Ito; Hiromi Sesaki; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1605. doi:

ARVO Annual Meeting Abstract June 2017

Quantifying the rate of ellipsoid zone loss in Stargardt disease

Cindy Cai; Jacob G Light; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1281. doi:

ARVO Annual Meeting Abstract June 2017

Evaluating the efficacy of treatment with an LXR agonist on the pathogenesis of early AMD

Faryan Tayyari; Mayur Choudhary; Peter Tontonoz; James T Handa; Goldis Malek

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1940. doi:

ARVO Annual Meeting Abstract June 2017

Nrf2 Protects Mitochondrial Function from Cigarette Smoke (CS) Independent of its Mitochondrial Antioxidant Capability.

Marisol del Valle Cano; Sayantan Datta; Lei Wang; Tongyun Liu; Sonny Dike; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5367. doi:

ARVO Annual Meeting Abstract September 2016

Pro-permeability Factors in Diabetic Macular Edema; the Diabetic Macular Edema Treated with Ozurdex (DMEO) Trial

Tahreem Aman Mir; Adrienne Scott; Lingmin He; Roomasa Channa; Catherine Mayerle; James T Handa; Saleema A. Kherani; Yong S. Han; Guohua Wang; Jiang Qian; Peter A Campochiaro

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3267. doi:

ARVO Annual Meeting Abstract September 2016

Age and oxidative stress in the retina

James T Handa

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Pink1 mediated mitophagy protects ARPE19 cells from mitochondrial damage

Sayantan Datta; Huan Mills; Marisol Cano; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5779. doi:

ARVO Annual Meeting Abstract September 2016

PTX3 Suppresses 4-HNE Induced Production of IL-1b, but not IL-18, by Retinal Pigment Epithelial (RPE) Cells

Lei Wang; Yara Gorashi; Marisol Cano; Katayoon B Ebrahimi; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5808. doi:

ARVO Annual Meeting Abstract September 2016

Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells

Mallika Valapala; Abdulla Alamri; Rhonda Grebe; J Samuel Zigler; James T Handa; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6048. doi:

ARVO Annual Meeting Abstract September 2016

Nrf2 and Hif1a have opposite responses to oxidative stress in ARPE-19 cells.

Hong Wei; James T Handa

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6049. doi:

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Foreword: Dry Age-Related Macular Degeneration

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

P2X7R inhibition activates autophagy and impairs the inflammasome response in the RPE

Visual Cycle Proteins Increase Acutely After Stimulation with CSE

Long-term visual and anatomical outcomes in treatment naïve neovascular age-related macular degeneration (nAMD) patients treated with anti-VEGF agents

The Diagnostic Utility of Ultrasound in the Management of Severe Corneal Ulcers and Non-infectious Corneal Melt

Pink1 and Nrf2 mediated mitochondrial retrograde signaling in RPE heterogeneity

Identification of endpoints appropriate in evaluating potential therapeutics for retinal degenerations using apoB100 transgenic mice.

αB-crystallin is active in Signaling, Autophagy, and Apoptosis in Ocular Melanoma

Visual and anatomical outcomes in NVAMD patients with subfoveal hemorrhage (SFH) treated with anti-VEGF agents

Pink1 deficiency induces Nrf2 dependent EMT and metabolic dysfunction in RPE cells

Quantifying the rate of ellipsoid zone loss in Stargardt disease

Evaluating the efficacy of treatment with an LXR agonist on the pathogenesis of early AMD

Nrf2 Protects Mitochondrial Function from Cigarette Smoke (CS) Independent of its Mitochondrial Antioxidant Capability.

Pro-permeability Factors in Diabetic Macular Edema; the Diabetic Macular Edema Treated with Ozurdex (DMEO) Trial

Age and oxidative stress in the retina

Pink1 mediated mitophagy protects ARPE19 cells from mitochondrial damage

PTX3 Suppresses 4-HNE Induced Production of IL-1b, but not IL-18, by Retinal Pigment Epithelial (RPE) Cells

Cellular effects of lysosomal dysfunction in retinal pigment epithelial cells

Nrf2 and Hif1a have opposite responses to oxidative stress in ARPE-19 cells.

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