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ARVO Annual Meeting Abstract July 2019

Development and efficacy assessment of AAV2/8-hG1.7p.coCNGA3, a CNGA3 gene therapy vector

Tassos Georgiadis; Takaaki Matsuki; Justin Hoke; Matteo Rizzi; Anai Gonzalez-Cordero; Robert Sampson; James WB Bainbridge; Alexander Smith; Robin R Ali

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3426. doi:

ARVO Annual Meeting Abstract July 2019

Early phase clinical trial of human embryonic stem cell-derived retinal pigmented epithelium transplantation in Stargardt disease: 5-year results

Manjit Singh Singh Mehat; James WB Bainbridge

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3940. doi:

ARVO Annual Meeting Abstract July 2019

Vitreous and plasma cytokine levels in subjects with advanced proliferative diabetic retinopathy in the Ranibizumab in Diabetic Vitrectomy (RaDiVit) Study

Oliver Comyn; Clemens Lange; James WB Bainbridge

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5362. doi:

ARVO Annual Meeting Abstract July 2019

Pharmacokinetics of the Anti-angiogenic Glycoprotein Opticin in Preclinical Studies

Eva Maria del Amo Páez; John R. Griffiths; Izabela P Klaska; Anne White; Leon Aarons; James WB Bainbridge; Richard J Unwin; Paul N Bishop

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2716. doi:

Retina May 2019

The Relationship Between Retinal Vessel Oxygenation and Spatial Distribution of Retinal Nonperfusion in Retinal Vascular Diseases

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Luke Nicholson; Clara Vazquez-Alfageme; Philip G. Hykin; James W. Bainbridge; Sobha Sivaprasad
TAGS: alveolar ventilation function, oximetry, retinal vessels, cell respiration, retinal vascular disorders
Invest. Ophthalmol. Vis. Sci.. 2019; 60(6):2083-2087. doi: 10.1167/iovs.18-24917

Genetics December 2018

Longitudinal Assessment of Retinal Structure in Achromatopsia Patients With Long-Term Follow-up

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Nashila Hirji; Michalis Georgiou; Angelos Kalitzeos; James W. Bainbridge; Neruban Kumaran; Jonathan Aboshiha; Joseph Carroll; Michel Michaelides
TAGS: cohort studies, follow-up, retina, achromatopsia, spectral-domain optical coherence tomography
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5735-5744. doi: 10.1167/iovs.18-25452

Includes: Supplemental Content

Retina August 2018

Mechanistic Evaluation of Panretinal Photocoagulation Versus Aflibercept in Proliferative Diabetic Retinopathy: CLARITY Substudy

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Luke Nicholson; Roxanne Crosby-Nwaobi; Joana C. Vasconcelos; A. Toby Prevost; Jayashree Ramu; Amy Riddell; James W. Bainbridge; Philip G. Hykin; Sobha Sivaprasad
TAGS: oximetry, eye, proliferative diabetic retinopathy, panretinal photocoagulation, aflibercept
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4277-4284. doi: 10.1167/iovs.17-23509

Includes: Supplemental Content

Clinical and Epidemiologic Research July 2018

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65 -Associated Leber Congenital Amaurosis

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Neruban Kumaran; Gary S. Rubin; Angelos Kalitzeos; Kaoru Fujinami; James W. B. Bainbridge; Richard G. Weleber; Michel Michaelides
TAGS: cohort studies, contrast sensitivity, genotype, longitudinal studies, perimetry, questionnaires, software, vision, visual acuity, visual fields
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3330-3339. doi: 10.1167/iovs.18-23873

Includes: Supplemental Content

Clinical and Epidemiologic Research January 2018

Severe Loss of Tritan Color Discrimination in RPE65 Associated Leber Congenital Amaurosis

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Neruban Kumaran; Caterina Ripamonti; Angelos Kalitzeos; Gary S. Rubin; James W. B. Bainbridge; Michel Michaelides
TAGS: color, leber's amaurosis, color vision
Invest. Ophthalmol. Vis. Sci.. 2018; 59(1):85-93. doi: 10.1167/iovs.17-22905

ARVO Annual Meeting Abstract June 2017

Human opticin reduces pathological preretinal neovascularization in the mouse model of oxygen-induced retinopathy.

Izabela Paulina Klaska; Catherine Orr; Anne White; Pilar Villacampa Alcubierre; Laura Abelleira Hervás; Justin Hoke; Catey V Bunce; Richard Unwin; Garth Cooper; Paul N Bishop; James W B Bainbridge

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4063. doi:

ARVO Annual Meeting Abstract June 2017

Severe Loss of Tritan Colour Discrimination in RPE65 Associated Leber Congenital Amaurosis

Neruban Kumaran; Caterina Ripamonti; Angelos Kalitzeos; James W B Bainbridge; Michel Michaelides

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4297. doi:

Retina June 2017

Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs

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Freya M. Mowat; Kristen J. Gervais; Laurence M. Occelli; Matthew J. Annear; Janice Querubin; James W. Bainbridge; Alexander J. Smith; Robin R. Ali; Simon M. Petersen-Jones
TAGS: retinal cone, dog, domestic, opsin, photoreceptors, rod photoreceptors, eye, retina, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3268-3277. doi: 10.1167/iovs.17-21930

ARVO Annual Meeting Abstract September 2016

Measurement of macular hole dimensions by OCT shadowgraphy

Saruban Pasu; Preena Tanna; James W B Bainbridge

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4252. doi:

ARVO Annual Meeting Abstract September 2016

Myeloid-derived VEGF and HIF are dispensable for ocular neovascularisation

Sidath Liyanage; Alessandro Fantin; Pilar Villacampa; Clemens Lange; Laura Denti; Enrico Cristante; Alexander J Smith; Robin R Ali; Ulrich F O Luhmann; James W B Bainbridge; Christiana Ruhrberg

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Impact of vitrectomy on outcomes of treatment for diabetic macular oedema with intravitreal ranibizumab

Sheelah Antao; Mark Fajgenbaum; Namritha Valerie Patrao; Roger Wong; Lyndon da Cruz; James W B Bainbridge; Ranjan Rajendram

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2091. doi:

ARVO Annual Meeting Abstract September 2016

Treatment outcomes of intravitreal ranibizumab for diabetic macular oedema in vitrectomised eyes

Vicky Hsin-Ju Lu; Sheelah Antao; Mark Fajgenbaum; Roger Wong; James W B Bainbridge; Lyndon da Cruz; Robin D Hamilton; Ranjan Rajendram

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2095. doi:

Genetics December 2015

Investigation of Aberrant Splicing Induced by AIPL1 Variations as a Cause of Leber Congenital Amaurosis

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James Bellingham; Alice E. Davidson; Jonathan Aboshiha; Francesca Simonelli; James W. Bainbridge; Michel Michaelides; Jacqueline van der Spuy
TAGS: mutation, exons, introns, rna splicing, rna, leber's amaurosis
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):7784-7793. doi: 10.1167/iovs.15-18092

Includes: Supplemental Content

Article November 2015

Spectral sensitivity measurements reveal partial success in restoring missing rod function with gene therapy

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Caterina Ripamonti; G. Bruce Henning; Scott J. Robbie; Venki Sundaram; L. Ingeborgh van den Born; Ingele Casteels; Thomy J. L. de Ravel; Anthony T. Moore; Alexander J. Smith; James W. Bainbridge; Robin R. Ali; Andrew Stockman
TAGS: gene therapy, retinal cone, rod photoreceptors, photopsia, bleach
Journal of Vision. 2015; 15(15):20. doi: 10.1167/15.15.20

ARVO Annual Meeting Abstract June 2015

VEGF-A 165 b reduces vascular dysfunction in the diabetic retina

Nikita Ved; Richard Hulse; Samuel Bestall; Lucy Donaldson; James W B Bainbridge; David Bates

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):926. doi:

ARVO Annual Meeting Abstract June 2015

Depot Indocyanine Green Dye for in vivo visualization of infiltrating leukocytes

Dawn A Sim; Colin J Chu; Michael B Powner; Senthil Selvam; Adnan Tufail; Catherine A Egan; James W B Bainbridge; Richard W J Lee; Andrew D Dick; Marcus Fruttiger

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4117. doi:

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Development and efficacy assessment of AAV2/8-hG1.7p.coCNGA3, a CNGA3 gene therapy vector

Early phase clinical trial of human embryonic stem cell-derived retinal pigmented epithelium transplantation in Stargardt disease: 5-year results

Vitreous and plasma cytokine levels in subjects with advanced proliferative diabetic retinopathy in the Ranibizumab in Diabetic Vitrectomy (RaDiVit) Study

Pharmacokinetics of the Anti-angiogenic Glycoprotein Opticin in Preclinical Studies

The Relationship Between Retinal Vessel Oxygenation and Spatial Distribution of Retinal Nonperfusion in Retinal Vascular Diseases

Longitudinal Assessment of Retinal Structure in Achromatopsia Patients With Long-Term Follow-up

Mechanistic Evaluation of Panretinal Photocoagulation Versus Aflibercept in Proliferative Diabetic Retinopathy: CLARITY Substudy

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65 -Associated Leber Congenital Amaurosis

Severe Loss of Tritan Color Discrimination in RPE65 Associated Leber Congenital Amaurosis

Human opticin reduces pathological preretinal neovascularization in the mouse model of oxygen-induced retinopathy.

Severe Loss of Tritan Colour Discrimination in RPE65 Associated Leber Congenital Amaurosis

Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs

Measurement of macular hole dimensions by OCT shadowgraphy

Myeloid-derived VEGF and HIF are dispensable for ocular neovascularisation

Impact of vitrectomy on outcomes of treatment for diabetic macular oedema with intravitreal ranibizumab

Treatment outcomes of intravitreal ranibizumab for diabetic macular oedema in vitrectomised eyes

Investigation of Aberrant Splicing Induced by AIPL1 Variations as a Cause of Leber Congenital Amaurosis

Spectral sensitivity measurements reveal partial success in restoring missing rod function with gene therapy

VEGF-A 165 b reduces vascular dysfunction in the diabetic retina

Depot Indocyanine Green Dye for in vivo visualization of infiltrating leukocytes

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