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Retina August 2020

Preservation of the Foveal Avascular Zone in Achromatopsia Despite the Absence of a Fully Formed Pit

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Rachel E. Linderman; Michalis Georgiou; Erica N. Woertz; Jenna A. Cava; Katie M. Litts; Sergey Tarima; Ranjan Rajendram; Jan M. Provis; Michel Michaelides; Joseph Carroll
TAGS: achromatopsia, diagnostic imaging, fovea centralis
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):52. doi: https://doi.org/10.1167/iovs.61.10.52

Includes: Supplemental Content

Retinal Cell Biology September 2018

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

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Nilisha Fernando; Yvette Wooff; Riemke Aggio-Bruce; Joshua A. Chu-Tan; Haihan Jiao; Catherine Dietrich; Matt Rutar; Melissa Rooke; Deepthi Menon; Janis T. Eells; Krisztina Valter; Philip G. Board; Jan Provis; Riccardo Natoli
TAGS: photoreceptors, retina, mice, oxidative stress
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4362-4374. doi: https://doi.org/10.1167/iovs.18-24627

Retinal Cell Biology August 2018

MicroRNA-124 Dysregulation is Associated With Retinal Inflammation and Photoreceptor Death in the Degenerating Retina

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Joshua A. Chu-Tan; Matt Rutar; Kartik Saxena; Riemke Aggio-Bruce; Rohan W. Essex; Krisztina Valter; Haihan Jiao; Nilisha Fernando; Yvette Wooff; Michele C. Madigan; Jan Provis; Riccardo Natoli
TAGS: micrornas, monocyte chemoattractant protein-1, photoreceptors, retina, retinal degeneration, retinitis
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4094-4105. doi: https://doi.org/10.1167/iovs.18-24623

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

MicroRNA-124 is redistributed from neurons to glia to reduce inflammation and slow progressive retinal degeneration

Joshua Aaron Chu-Tan; Matt Rutar; Kartik Saxena; Riemke Aggio-Bruce; Rohan W. Essex; Krisztina Valter; Haihan Jiao; Michele C Madigan; Jan Provis; Riccardo Natoli

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4604. doi:

ARVO Annual Meeting Abstract July 2018

Obesity-induced metabolic disturbance drives complement activation by retinal microglia

Matt Rutar; Riccardo Natoli; Nilisha Fernando; Jan Provis

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4606. doi:

ARVO Annual Meeting Abstract July 2018

MicroRNAs regulate NLRP3 inflammasome activation by microglia and macrophages in retinal degeneration

Nilisha Fernando; Riemke Aggio-Bruce; Yvette Wooff; Joshua Aaron Chu-Tan; Kasthuri Chandra Babu; Krisztina Valter; Jan Provis; Riccardo Natoli

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4607. doi:

ARVO Annual Meeting Abstract June 2017

Retinal monocyte-derived complement, not systemically derived complement contributes to the early onset of focal retinal degeneration

Haihan Jiao; Riccardo Natoli; Nilisha Fernando; Tanja Racic; Joshua Chu-Tan; Krisztina Valter; Matt Rutar; Jan Provis

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1624. doi:

Retinal Cell Biology June 2017

Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration

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Riccardo Natoli; Nilisha Fernando; Haihan Jiao; Tanja Racic; Michele Madigan; Nigel L. Barnett; Joshua A. Chu-Tan; Krisztina Valter; Jan Provis; Matt Rutar
TAGS: atrophy, complement system proteins, macrophages, retina, retinal degeneration, mice, rna, small interfering
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):2977-2990. doi: https://doi.org/10.1167/iovs.17-21672

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Improving face recognition in age-related macular degeneration via caricaturing

Jo Lane; Nick Barnes; Xuming He; Rohan W Essex; Ted Maddess; Emilie Rohan; Tamara Gradden; Jan Provis; Elinor McKone

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):23. doi:

ARVO Annual Meeting Abstract September 2016

The value of broad spectrum chemokine inhibitors in modulating microglia/macrophage-mediated inflammation in a model of atrophic AMD

Matt Rutar; Nilisha Fernando; Riccardo Natoli; Jan Provis; Krisztina Valter

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Chronic accumulations of complement-expressing microglia/macrophages accompany the progressive expansion of the retinal lesion in an animal model of atrophic AMD

Nilisha Fernando; Tanja Racic; Riccardo Natoli; Krisztina Valter; Jan Provis; Matt Rutar

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2222. doi:

ARVO Annual Meeting Abstract September 2016

Dark-Rearing (DR) precludes the initiating event in OIR and eliminates the pathology seen in the second phase of disease: Rationale for novel non-invasive treatment for ROP.

Tailoi Chan-Ling; Nigel L Barnett; Rita Maccarone; Jan Provis; Mark Koina; Ping Hu; Riccardo Natoli; Silvia Bisti; Robert A Linsenmeier; Samuel Adamson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Biochemistry and Molecular Biology November 2015

Proteomic Analysis of Embryonic and Young Human Vitreous

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Kenneth M. P. Yee; Edward P. Feener; Michele Madigan; Nicholas J. Jackson; Ben-Bo Gao; Fred N. Ross-Cisneros; Jan Provis; Lloyd Paul Aiello; Alfredo A. Sadun; J. Sebag
TAGS: embryo, proteins, proteomics, vitreous body, immunohistochemistry, fetus
Invest. Ophthalmol. Vis. Sci.. 2015; 56(12):7036-7042. doi: https://doi.org/10.1167/iovs.15-16809

Includes: Supplemental Content

Retina March 2015

Identification of miRNAs in a Model of Retinal Degenerations

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Kartik Saxena; Matthew Viktor Rutar; Jan M. Provis; Riccardo Carlo Natoli
TAGS: micrornas, retinal degeneration
Invest. Ophthalmol. Vis. Sci.. 2015; 56(3):1820-1829. doi: https://doi.org/10.1167/iovs.14-15449

ARVO Annual Meeting Abstract April 2014

Dark-Rearing (DR) Mitigates Pre-Retinal Neovascularization and OIR Pathology with no Detriment To Visual Function and Morphology: Compelling Evidence For DR as Non-Invasive Intervention in Retinopathy of Prematurity (ROP)

Tailoi Chan-Ling; Samuel Adamson; Riccardo Natoli; Rita Maccarone; Mark Koina; Ping Hu; Jennifer C Lau; Jan M Provis; Robert A Linsenmeier; Silvia Bisti

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5902. doi:

Article February 2014

A new theoretical approach to improving face recognition in disorders of central vision: Face caricaturing

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Jessica Irons; Elinor McKone; Rachael Dumbleton; Nick Barnes; Xuming He; Jan Provis; Callin Ivanovici; Alisa Kwa
TAGS: face, vision, facial recognition
Journal of Vision. 2014; 14(2):12. doi: https://doi.org/10.1167/14.2.12

Vision Sciences Society Annual Meeting Abstract July 2013

Caricaturing improves face recognition in simulated age-related macular degeneration.

Elinor McKone; Jessica Irons; Xuming He; Nick Barnes; Jan Provis; Rachael Dumbleton; Callin Ivanovici; Alisa Kwa

Journal of Vision. 2013; 13(9):996. doi: https://doi.org/10.1167/13.9.996

ARVO Annual Meeting Abstract June 2013

Structured Method for Assessing Macular Holes by OCT and Correlations with Visual Outcomes

Zabrina Abdool; Jan Provis; William Campbell; Alex Hunyor; Ian McAllister; Rohan Essex

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3849. doi:

ARVO Annual Meeting Abstract June 2013

Chemokine-mediated guidance of the inflammatory response by Müller cells, microglia, and RPE in an animal model of atrophic AMD

Matt Rutar; Rong Xian Chia; Riccardo Natoli; Jan Provis

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3665. doi:

ARVO Annual Meeting Abstract March 2012

Dark Rearing (DR) as a means of mimicking ‘Physiological Hypoxia’: A rationale for non-invasive treatment of Retinopathy of Prematurity

Samuel J. Adamson; Peter Kozulin; Rita Maccarone; Steven Yun; Ping Hu; Silvia Bisti; Jan Provis; Michele C. Madigan; Janet McColm; Tailoi Chan-Ling

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5886. doi:

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Preservation of the Foveal Avascular Zone in Achromatopsia Despite the Absence of a Fully Formed Pit

Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina

MicroRNA-124 Dysregulation is Associated With Retinal Inflammation and Photoreceptor Death in the Degenerating Retina

MicroRNA-124 is redistributed from neurons to glia to reduce inflammation and slow progressive retinal degeneration

Obesity-induced metabolic disturbance drives complement activation by retinal microglia

MicroRNAs regulate NLRP3 inflammasome activation by microglia and macrophages in retinal degeneration

Retinal monocyte-derived complement, not systemically derived complement contributes to the early onset of focal retinal degeneration

Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration

Improving face recognition in age-related macular degeneration via caricaturing

The value of broad spectrum chemokine inhibitors in modulating microglia/macrophage-mediated inflammation in a model of atrophic AMD

Chronic accumulations of complement-expressing microglia/macrophages accompany the progressive expansion of the retinal lesion in an animal model of atrophic AMD

Dark-Rearing (DR) precludes the initiating event in OIR and eliminates the pathology seen in the second phase of disease: Rationale for novel non-invasive treatment for ROP.

Proteomic Analysis of Embryonic and Young Human Vitreous

Identification of miRNAs in a Model of Retinal Degenerations

Dark-Rearing (DR) Mitigates Pre-Retinal Neovascularization and OIR Pathology with no Detriment To Visual Function and Morphology: Compelling Evidence For DR as Non-Invasive Intervention in Retinopathy of Prematurity (ROP)

A new theoretical approach to improving face recognition in disorders of central vision: Face caricaturing

Caricaturing improves face recognition in simulated age-related macular degeneration.

Structured Method for Assessing Macular Holes by OCT and Correlations with Visual Outcomes

Chemokine-mediated guidance of the inflammatory response by Müller cells, microglia, and RPE in an animal model of atrophic AMD

Dark Rearing (DR) as a means of mimicking ‘Physiological Hypoxia’: A rationale for non-invasive treatment of Retinopathy of Prematurity

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