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ARVO Annual Meeting Abstract June 2024

Prevention of photoreceptor loss by modulation of glucose metabolism

Vaishnavi Karthikeyan; Rossella Valenzano; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1576.

ARVO Annual Meeting Abstract June 2024

AAV-CRISPR/Cas9-Mediated Gene Rescue in USH2A Knock-out hiPSC-Derived Retinal Organoids

Rossella Valenzano; Andrew McDonald; Ioannis Moustakas; Aat Mulder; Hailiang Mei; Roman I. Koning; Manuel A.F.V. Gonçalves; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1553.

ARVO Annual Meeting Abstract June 2022

Four-year prospective follow-up in patients with CRB1 -associated retinal dystrophies

Jessica Serena Karuntu; Xuan-Thanh-An Nguyen; Mays Talib; Mary J. van Schooneveld; Jan Wijnholds; Mies M. van Genderen; Nicoline E. Schalij-Delfos; Caroline C W Klaver; Ralph J. Florijn; Jacoline B ten Brink; Magda M. Meester-Smoor; L. Ingeborgh van den Born; Carel C B Hoyng; Alberta A H J Thiadens; Arthur A. Bergen; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4479 – F0266.

ARVO Annual Meeting Abstract June 2020

A two-year prospective natural history study in patients with CRB1-associated retinal dystrophies: establishing clinical endpoints for future gene therapy trials

Xuan-Thanh-An Nguyen; Mays Talib; Mary J. van Schooneveld; Jan Wijnholds; Maria M. van Genderen; Ralph J. Florijn; Jacoline ten Brink; Frans P Cremers; Magda A. Meester; Caroline Klaver; L. Ingeborgh van den Born; Carel C B Hoyng; Alberta Thiadens; Arthur Bergen; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3051.

ARVO Annual Meeting Abstract July 2019

Adeno-associated viral (AAV) vector tropism in the young Brown Norway rat retina

Nanda Boon; C. Henrique Alves; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3410.

Retina August 2018

The Spectrum of Structural and Functional Abnormalities in Female Carriers of Pathogenic Variants in the RPGR Gene

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Mays Talib; Mary J. van Schooneveld; Caroline Van Cauwenbergh; Jan Wijnholds; Jacoline B. ten Brink; Ralph J. Florijn; Nicoline E. Schalij-Delfos; Gislin Dagnelie; Maria M. van Genderen; Elfride De Baere; Magda A. Meester-Smoor; Julie De Zaeytijd; Frans P. M. Cremers; L. Ingeborgh van den Born; Alberta A. Thiadens; Carel B. Hoyng; Caroline C. Klaver; Bart P. Leroy; Arthur A. Bergen; Camiel J. F. Boon
TAGS: genes, heterozygote, phenotype, signs and symptoms
Invest. Ophthalmol. Vis. Sci.. 2018; 59(10):4123-4133. https://doi.org/10.1167/iovs.17-23453

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Extensive phenotyping in CRB1 -associated retinal dystrophies: defining clinical endpoints for gene therapy trials

Mays Talib; Mary van Schooneveld; Jan Wijnholds; Maria M van Genderen; N. Schalij-Delofs; Ralph Florijn; Frans P Cremers; Ingeborgh Born; Alberta A H J Thiadens; Carel C B Hoyng; Caroline C W Klaver; Arthur A Bergen; Camiel Boon

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):43.

ARVO Annual Meeting Abstract July 2018

Inner- and outer segments are required for efficient photoreceptor infection and expression in cultured human retina

Thilo Matthias Buck; Peter M Quinn; Camiel Boon; Celso H F Alves; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4540.

ARVO Annual Meeting Abstract July 2018

Ablation of CRB2 in Rod Photoreceptors with Concomitant Loss of CRB1 in Müller Glial Cells Mimics Retinitis Pigmentosa

Celso H F Alves; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4970.

ARVO Annual Meeting Abstract June 2017

Recapitulation of the Human Fetal Crumbs Complex in human iPSCs-derived Retinas and Retinal Pigment Epithelium

Peter M Quinn; Thilo Matthias Buck; Celso Alves; Charlotte Ohonin; Susana M Chuva de Sousa Lopes; Harald Mikkers; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3758.

ARVO Annual Meeting Abstract June 2017

Potency assay for AAV-gene vectors in human iPSCs-derived retinas and donor retinas

Thilo Matthias Buck; Peter M Quinn; Celso Alves; Elon Van Dijk; Charlotte Ohonin; Camiel J F Boon; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4093.

ARVO Annual Meeting Abstract June 2017

Reduction of CRB2 Specifically in Mouse Photoreceptors with Concomitant Loss of CRB1 in Müller Glial Cells Mimics Early-onset Retinitis Pigmentosa

Celso Alves; Peter M Quinn; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5386.

ARVO Annual Meeting Abstract June 2017

RPGR -associated retinal dystrophies: a longitudinal study

Mays Talib; Mary J van Schooneveld; Jan Wijnholds; Nicoline Schalij-Delfos; Ralph J. Florijn; Ingeborgh Van Den Born; Frans P Cremers; Alberta A H J Thiadens; Carel C B Hoyng; Caroline Klaver; Arthur Bergen; Camiel J F Boon

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2012.

ARVO Annual Meeting Abstract September 2016

Ablation of Crb2 Specifically in Mouse Photoreceptors with Crb1 loss in Müller Cells Mimics Leber Congenital Amaurosis

Thilo Matthias Buck; Peter M Quinn; Jan Klooster; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1777.

ARVO Annual Meeting Abstract September 2016

Ablation of Crb1 and Crb2 Specifically in Mouse Müller Cells mimics early onset Retinitis Pigmentosa

Peter M Quinn; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2271.

ARVO Annual Meeting Abstract June 2015

Gene Therapy into Photoreceptors and Müller Glial Cells Restores Retinal Structure and Function in Crb1 Retinitis Pigmentosa Mouse Models

Jan Wijnholds; C. Henrique F. Alves; Peter Quinn; Rogier Vos; Jan Klooster; John Gerard Flannery; J. Alexander Heimel; Lucie P Pellissier

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2067.

ARVO Annual Meeting Abstract June 2015

Characterization of CRB1 gene therapy in a retinal degeneration mouse model

Timothy P Day; Trevor Lee; Jan Wijnholds; David Schaffer; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3633.

ARVO Annual Meeting Abstract April 2014

Targeted ablation of Crb2 in photoreceptor cells induces Retinitis Pigmentosa

Celso Henrique Freitas Alves; Lucie P Pellissier; Marina Garcia Garrido; Vithiyanjali Sothilingam; Christina Seide; Susanne C Beck; John Gerard Flannery; Mathias W Seeliger; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1638.

ARVO Annual Meeting Abstract April 2014

CRB proteins expression and localization in human retina

Lucie Pellissier; Jan Klooster; Jan Wijnholds

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2686.

ARVO Annual Meeting Abstract March 2012

Adult Müller Glia Cells Are Efficient Progenitor Cells For Starburst Amacrine Cells

Jan Wijnholds; Pete Quinn; Ditte M. Lundvig; Lucie P. Pellissier; Berend Hooibrink; Robert M. Hoek

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3972.

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Prevention of photoreceptor loss by modulation of glucose metabolism

AAV-CRISPR/Cas9-Mediated Gene Rescue in USH2A Knock-out hiPSC-Derived Retinal Organoids

Four-year prospective follow-up in patients with CRB1 -associated retinal dystrophies

A two-year prospective natural history study in patients with CRB1-associated retinal dystrophies: establishing clinical endpoints for future gene therapy trials

Adeno-associated viral (AAV) vector tropism in the young Brown Norway rat retina

The Spectrum of Structural and Functional Abnormalities in Female Carriers of Pathogenic Variants in the RPGR Gene

Extensive phenotyping in CRB1 -associated retinal dystrophies: defining clinical endpoints for gene therapy trials

Inner- and outer segments are required for efficient photoreceptor infection and expression in cultured human retina

Ablation of CRB2 in Rod Photoreceptors with Concomitant Loss of CRB1 in Müller Glial Cells Mimics Retinitis Pigmentosa

Recapitulation of the Human Fetal Crumbs Complex in human iPSCs-derived Retinas and Retinal Pigment Epithelium

Potency assay for AAV-gene vectors in human iPSCs-derived retinas and donor retinas

Reduction of CRB2 Specifically in Mouse Photoreceptors with Concomitant Loss of CRB1 in Müller Glial Cells Mimics Early-onset Retinitis Pigmentosa

RPGR -associated retinal dystrophies: a longitudinal study

Ablation of Crb2 Specifically in Mouse Photoreceptors with Crb1 loss in Müller Cells Mimics Leber Congenital Amaurosis

Ablation of Crb1 and Crb2 Specifically in Mouse Müller Cells mimics early onset Retinitis Pigmentosa

Gene Therapy into Photoreceptors and Müller Glial Cells Restores Retinal Structure and Function in Crb1 Retinitis Pigmentosa Mouse Models

Characterization of CRB1 gene therapy in a retinal degeneration mouse model

Targeted ablation of Crb2 in photoreceptor cells induces Retinitis Pigmentosa

CRB proteins expression and localization in human retina

Adult Müller Glia Cells Are Efficient Progenitor Cells For Starburst Amacrine Cells

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