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Articles August 2021

Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

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Louis R. Pasquale; Li Gong; Janey L. Wiggs; Lingzhen Pan; Zhenyan Yang; Mingling Wu; Zunyuan Yang; Dong Feng Chen; Wen Zeng
TAGS: cercopithecidae, glaucoma, macaca mulatta, open-angle glaucoma, intraocular pressure, china
Trans. Vis. Sci. Tech.. 2021; 10(9):20. doi: https://doi.org/10.1167/tvst.10.9.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Stuart MacGregor; Xikun Han; Puya Gharahkhani; Maciej Trzaskowski; Jamie E Craig; Alex W Hewitt; David A Mackey; Janey L Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1512. doi:

ARVO Annual Meeting Abstract June 2021

Whole Genome Sequencing of Large Consanguineous Pedigrees from South India Identifies New Candidate Genes for Lens Thickness

Baojian Fan; P Ferdina Marie Sharmila; N Soumittra; Sripriya Sarangapani; David S. Friedman; L Vijaya; Jonathan L Haines; Ronnie George; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1505. doi:

ARVO Annual Meeting Abstract June 2021

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Christian James Pompoco; Chase Paulson; Samuel C. Taylor; Brian Craig Stagg; Robert Ritch; Jae H Kang; Janey L Wiggs; Louis R Pasquale; Karen Curtin; Barbara M Wirostko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):71. doi:

ARVO Annual Meeting Abstract June 2021

Penetrance and characteristics of Gln368Ter Myocilin variant in UKBB

Nazlee Zebardast; Sayuri Sekimitsu; Tobias Elze; Jiali Wang; Michael Lin; Brian Cole; Ayellet V Segre; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1511. doi:

ARVO Annual Meeting Abstract June 2021

Heritability of Primary Angle Closure Anatomic Traits and Predictors of Angle Closure in South Indian Siblings

Elizabeth Ciociola; Srinivasan Kavitha; Sabyasachi Sengupta; Janey L Wiggs; Mohideen Abdul Kader; Ganesh V Raman; Sharmila Rajendrababu; Pradeep Y Ramulu; Rengaraj Venkatesh; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1510. doi:

ARVO Annual Meeting Abstract June 2021

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Louis R Pasquale; Jae H Kang; Bernard Rosner; Janey L Wiggs; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3499. doi:

ARVO Annual Meeting Abstract June 2021

Automated detection of genetic relatedness from fundus photographs using Convolutional Siamese Neural Networks

Nishanth Arun; Praveer Singh; Jiali Wang; Ayellet V Segre; Janey L Wiggs; Brian Cole; Jayashree Kalpathy-Cramer; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1034. doi:

ARVO Annual Meeting Abstract June 2021

A prospective study of the natural history of MYOC -associated juvenile open-angle glaucoma

Edward Ryan Collantes; Manuel Jr. Delfin; Ferdinand Atienza; Baojian Fan; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1496. doi:

ARVO Annual Meeting Abstract June 2021

Lack of association of primary open angle glaucoma with expansion of the ATXN2 trinucleotide repeat involved in spinocerebellar ataxia 2 and amyotrophic lateral sclerosis

Shi Song Rong; Robert Igo; Jessica Cooke Bailey; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1493. doi:

ARVO Annual Meeting Abstract June 2021

Genetic analyses identify the first two genetic loci associated with sporadic pigment dispersion syndrome and indicate myopia is a causal factor for disease onset

Mark James Simcoe; Baojian Fan; naushin waseem; Nicole Weisschuh; Omar Abdul Rahman Mahroo; Helene Choquet; Janey L Wiggs; David F Garway-Heath; Pirro G Hysi; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1591. doi:

ARVO Annual Meeting Abstract June 2021

Establishing Standardized Criteria to Improve the Interpretation of Genetic Testing for Ocular Disorders

Kristy Lee; Emily Place; Radha Ayyagari; Rui Chen; Kerry Goetz; Robert B Hufnagel; Linda Reis; Susanne Roosing; Emmanuelle Souzeau; Patrick Yu-Wai-Man; Brian Mansfield; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1566. doi:

Genetics July 2020

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

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Milica A. Margeta; Sophia M. Letcher; Robert P. Igo, Jr.; Jessica N. Cooke Bailey; Louis R. Pasquale; Jonathan L. Haines; Oleg Butovsky; Janey L. Wiggs; for the NEIGHBORHOOD consortium
TAGS: apolipoprotein e, glaucoma, open-angle glaucoma, trem2 gene, alleles
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):3. doi: https://doi.org/10.1167/iovs.61.8.3

ARVO Annual Meeting Abstract July 2019

Glaucoma Examination in the Amish of Holmes County, Ohio

Jonathan Mikal Skarie; Tyler Kinzy; Jane Sewell; Yeunjoo E. Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Erika Trapl; Farren BS Briggs; Louis R Pasquale; Janey L Wiggs; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1602. doi:

ARVO Annual Meeting Abstract July 2019

Whole exome sequencing identifies GPC6 as a candidate early-onset glaucoma gene

Shiming Li; Baojian Fan; Anna Larson; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1609. doi:

ARVO Annual Meeting Abstract July 2019

APEX1 as a new candidate gene for glaucoma

Paulo Vinicius Svidnicki; Monica B Melo; Jose Paulo C Vasconcellos; Shi Song Rong; Anna Larson; John Simmons Borchert; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1614. doi:

ARVO Annual Meeting Abstract July 2019

Family-based Genome-wide Association Study in South Indian Consanguineous Pedigrees Identifies an Association between LPHN3 and Vertical Cup-disc Ratio

Baojian Fan; P Ferdina Marie Sharmila; N Soumittra; S Sripriya; X. Raymond Gao; David S Friedman; L Vijaya; Jonathan L Haines; Ronnie J George; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1618. doi:

ARVO Annual Meeting Abstract July 2019

A glaucoma polygenic risk score strongly associated with disease prediction and treatment intensity.

Jamie E Craig; Ayub Qassim; Xikun Han; Mark Hassall; Robert James Casson; Stuart L Graham; David A Mackey; Colin Willoughby; Kathryn P Burdon; John Landers; Emmanuelle Souzeau; Janey L Wiggs; Alex W Hewitt; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1619. doi:

ARVO Annual Meeting Abstract July 2019

Association of APOE with POAG suggests a protective effect for APOE4

Sophia M Letcher; Milica Margeta; Robert P. Igo; Jessica Cooke Bailey; Jonathan L Haines; Oleg Butovsky; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1627. doi:

ARVO Annual Meeting Abstract July 2019

Rare ATXN2 Variants in Cases with Primary Open Angle Glaucoma Cause Visual Impairment in Zebrafish

Shi Song Rong; Anna Larson; John Simmons Borchert; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2833. doi:

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Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Whole Genome Sequencing of Large Consanguineous Pedigrees from South India Identifies New Candidate Genes for Lens Thickness

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Penetrance and characteristics of Gln368Ter Myocilin variant in UKBB

Heritability of Primary Angle Closure Anatomic Traits and Predictors of Angle Closure in South Indian Siblings

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Automated detection of genetic relatedness from fundus photographs using Convolutional Siamese Neural Networks

A prospective study of the natural history of MYOC -associated juvenile open-angle glaucoma

Lack of association of primary open angle glaucoma with expansion of the ATXN2 trinucleotide repeat involved in spinocerebellar ataxia 2 and amyotrophic lateral sclerosis

Genetic analyses identify the first two genetic loci associated with sporadic pigment dispersion syndrome and indicate myopia is a causal factor for disease onset

Establishing Standardized Criteria to Improve the Interpretation of Genetic Testing for Ocular Disorders

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

Glaucoma Examination in the Amish of Holmes County, Ohio

Whole exome sequencing identifies GPC6 as a candidate early-onset glaucoma gene

APEX1 as a new candidate gene for glaucoma

Family-based Genome-wide Association Study in South Indian Consanguineous Pedigrees Identifies an Association between LPHN3 and Vertical Cup-disc Ratio

A glaucoma polygenic risk score strongly associated with disease prediction and treatment intensity.

Association of APOE with POAG suggests a protective effect for APOE4

Rare ATXN2 Variants in Cases with Primary Open Angle Glaucoma Cause Visual Impairment in Zebrafish

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