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Articles August 2021

Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

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Louis R. Pasquale; Li Gong; Janey L. Wiggs; Lingzhen Pan; Zhenyan Yang; Mingling Wu; Zunyuan Yang; Dong Feng Chen; Wen Zeng
TAGS: cercopithecidae, glaucoma, macaca mulatta, open-angle glaucoma, intraocular pressure, china
Trans. Vis. Sci. Tech.. 2021; 10(9):20. doi: https://doi.org/10.1167/tvst.10.9.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Automated detection of genetic relatedness from fundus photographs using Convolutional Siamese Neural Networks

Nishanth Arun; Praveer Singh; Jiali Wang; Ayellet V Segre; Janey L Wiggs; Brian Cole; Jayashree Kalpathy-Cramer; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1034. doi:

ARVO Annual Meeting Abstract June 2021

A prospective study of the natural history of MYOC -associated juvenile open-angle glaucoma

Edward Ryan Collantes; Manuel Jr. Delfin; Ferdinand Atienza; Baojian Fan; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1496. doi:

ARVO Annual Meeting Abstract June 2021

Lack of association of primary open angle glaucoma with expansion of the ATXN2 trinucleotide repeat involved in spinocerebellar ataxia 2 and amyotrophic lateral sclerosis

Shi Song Rong; Robert Igo; Jessica Cooke Bailey; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1493. doi:

ARVO Annual Meeting Abstract June 2021

Genetic analyses identify the first two genetic loci associated with sporadic pigment dispersion syndrome and indicate myopia is a causal factor for disease onset

Mark James Simcoe; Baojian Fan; naushin waseem; Nicole Weisschuh; Omar Abdul Rahman Mahroo; Helene Choquet; Janey L Wiggs; David F Garway-Heath; Pirro G Hysi; Christopher J Hammond

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1591. doi:

ARVO Annual Meeting Abstract June 2021

Establishing Standardized Criteria to Improve the Interpretation of Genetic Testing for Ocular Disorders

Kristy Lee; Emily Place; Radha Ayyagari; Rui Chen; Kerry Goetz; Robert B Hufnagel; Linda Reis; Susanne Roosing; Emmanuelle Souzeau; Patrick Yu-Wai-Man; Brian Mansfield; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1566. doi:

ARVO Annual Meeting Abstract June 2021

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Stuart MacGregor; Xikun Han; Puya Gharahkhani; Maciej Trzaskowski; Jamie E Craig; Alex W Hewitt; David A Mackey; Janey L Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1512. doi:

ARVO Annual Meeting Abstract June 2021

Whole Genome Sequencing of Large Consanguineous Pedigrees from South India Identifies New Candidate Genes for Lens Thickness

Baojian Fan; P Ferdina Marie Sharmila; N Soumittra; Sripriya Sarangapani; David S. Friedman; L Vijaya; Jonathan L Haines; Ronnie George; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1505. doi:

ARVO Annual Meeting Abstract June 2021

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Christian James Pompoco; Chase Paulson; Samuel C. Taylor; Brian Craig Stagg; Robert Ritch; Jae H Kang; Janey L Wiggs; Louis R Pasquale; Karen Curtin; Barbara M Wirostko

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):71. doi:

ARVO Annual Meeting Abstract June 2021

Penetrance and characteristics of Gln368Ter Myocilin variant in UKBB

Nazlee Zebardast; Sayuri Sekimitsu; Tobias Elze; Jiali Wang; Michael Lin; Brian Cole; Ayellet V Segre; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1511. doi:

ARVO Annual Meeting Abstract June 2021

Heritability of Primary Angle Closure Anatomic Traits and Predictors of Angle Closure in South Indian Siblings

Elizabeth Ciociola; Srinivasan Kavitha; Sabyasachi Sengupta; Janey L Wiggs; Mohideen Abdul Kader; Ganesh V Raman; Sharmila Rajendrababu; Pradeep Y Ramulu; Rengaraj Venkatesh; Nazlee Zebardast

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1510. doi:

ARVO Annual Meeting Abstract June 2021

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Louis R Pasquale; Jae H Kang; Bernard Rosner; Janey L Wiggs; Mengyu Wang; Tobias Elze

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3499. doi:

Genetics July 2020

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

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Milica A. Margeta; Sophia M. Letcher; Robert P. Igo, Jr.; Jessica N. Cooke Bailey; Louis R. Pasquale; Jonathan L. Haines; Oleg Butovsky; Janey L. Wiggs; for the NEIGHBORHOOD consortium
TAGS: apolipoprotein e, glaucoma, open-angle glaucoma, trem2 gene, alleles
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):3. doi: https://doi.org/10.1167/iovs.61.8.3

ARVO Annual Meeting Abstract June 2020

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Janey Wiggs; Puya Gharahkhani; Eric Jorgenson; Pirro G Hysi; Anthony Khawaja; Sarah Pendergrass; Xikun Han; David Mackey; Christopher Hammond; Michael A Hauser; Louis R Pasquale; Caroline Klaver; Michiaki Kubo; Tin Aung; Jamie E Craig; Stuart MacGregor

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1890. doi:

ARVO Annual Meeting Abstract June 2020

Evidence for a causal link between pseudoexfoliation syndrome and myocardial infarction using Mendelian randomization

Marianne T Kennedy Neary; Oliver J Kennedy; George Davey Smith; Pirro G Hysi; Louis R Pasquale; Janey Wiggs; Anthony P Khawaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2738. doi:

ARVO Annual Meeting Abstract June 2020

Calcium Channel Blocker Use and Risk of Glaucoma in a Large United Kingdom Population

Alan Kastner; Giovanni Montesano; C Gustavo De Moraes; Jae H. Kang; Janey Wiggs; Louis Pasquale; Pirro G Hysi; Sharon Chua; Praveen J Patel; Paul J Foster; Sir Peng T. Khaw; Anthony Khawaja

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2739. doi:

ARVO Annual Meeting Abstract June 2020

The Prevalence of Primary Open-Angle Glaucoma-Like Features in a Rhesus Macaque Colony from Southern China

Louis R Pasquale; Li Gong; Janey Wiggs; Lingzhen Pan; Zhenyan Yang; Mingling Wu; Dongfeng Chen; Wen Zeng

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1436. doi:

ARVO Annual Meeting Abstract June 2020

Association of coffee, tea, and caffeine consumption with intraocular pressure and interaction with genetic risk: findings from the UK Biobank

Jihye Kim; Hugues Aschard; Jae H. Kang; Marleen AH Lentjes; Janey Wiggs; Anthony Khawaja; Louis R Pasquale

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):52. doi:

ARVO Annual Meeting Abstract June 2020

Genome-Wide Gene-Environment Interaction Analysis of Body Mass Index and Vertical Cup-Disc Ratio in a Latino Population

Yingjie Li; Janey Wiggs; Xiaoyi Raymond Gao

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):68. doi:

ARVO Annual Meeting Abstract June 2020

Integrative Prioritization of IOP-associated Genes Using High Throughput Genomic Data

Yutao Liu; Emily Parker; Hannah Youngblood; Jingwen Cai; Kristin Marie Perkumas; Janey Wiggs; Louis R Pasquale; Michael A Hauser; Daniel Stamer

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):990. doi:

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Development of Primary Open Angle Glaucoma-Like Features in a Rhesus Macaque Colony From Southern China

Automated detection of genetic relatedness from fundus photographs using Convolutional Siamese Neural Networks

A prospective study of the natural history of MYOC -associated juvenile open-angle glaucoma

Lack of association of primary open angle glaucoma with expansion of the ATXN2 trinucleotide repeat involved in spinocerebellar ataxia 2 and amyotrophic lateral sclerosis

Genetic analyses identify the first two genetic loci associated with sporadic pigment dispersion syndrome and indicate myopia is a causal factor for disease onset

Establishing Standardized Criteria to Improve the Interpretation of Genetic Testing for Ocular Disorders

Combining glaucoma and correlated risk factors dramatically expands gene discovery for glaucoma

Whole Genome Sequencing of Large Consanguineous Pedigrees from South India Identifies New Candidate Genes for Lens Thickness

Association of Non-Melanoma Skin Cancer with Exfoliation Syndrome: The Utah Project of Exfoliation Syndrome

Penetrance and characteristics of Gln368Ter Myocilin variant in UKBB

Heritability of Primary Angle Closure Anatomic Traits and Predictors of Angle Closure in South Indian Siblings

An autonomous algorithm shows that African and Hispanic Americans with primary open-angle glaucoma present with severe visual field loss patterns

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma, and shows a genetic link to Alzheimer’s disease.

Evidence for a causal link between pseudoexfoliation syndrome and myocardial infarction using Mendelian randomization

Calcium Channel Blocker Use and Risk of Glaucoma in a Large United Kingdom Population

The Prevalence of Primary Open-Angle Glaucoma-Like Features in a Rhesus Macaque Colony from Southern China

Association of coffee, tea, and caffeine consumption with intraocular pressure and interaction with genetic risk: findings from the UK Biobank

Genome-Wide Gene-Environment Interaction Analysis of Body Mass Index and Vertical Cup-Disc Ratio in a Latino Population

Integrative Prioritization of IOP-associated Genes Using High Throughput Genomic Data

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