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ARVO Annual Meeting Abstract June 2015

Nitroxide free radicals protect macular xanthophylls against chemical destruction (bleaching) during lipid peroxidation

Mariusz Zareba; Janice M Burke; Witold Karol Subczynski

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4669. doi:

Retinal Cell Biology August 2014

Photic Injury to Cultured RPE Varies Among Individual Cells in Proportion to Their Endogenous Lipofuscin Content as Modulated by Their Melanosome Content

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Mariusz Zareba; Christine M. B. Skumatz; Tadeusz J. Sarna; Janice M. Burke
TAGS: granules, lipofuscin, melanosomes, stress, retinal pigment cell, wounds and injuries
Invest. Ophthalmol. Vis. Sci.. 2014; 55(8):4982-4990. doi: https://doi.org/10.1167/iovs.14-14310

Retinal Cell Biology March 2013

Photosensitized Oxidative Stress to ARPE-19 Cells Decreases Protein Receptors that Mediate Photoreceptor Outer Segment Phagocytosis

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Magdalena M. Olchawa; Anja M. Herrnreiter; Christine M. B. Skumatz; Mariusz Zareba; Tadeusz J. Sarna; Janice M. Burke
TAGS: integrins, oxidative stress, phagocytosis, photoreceptors, proteins, receptor, stress, phototoxic dermatitis, photosensitizing agents, actins
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):2276-2287. doi: https://doi.org/10.1167/iovs.12-11154

Retinal Cell Biology January 2013

Oxidative Stress Increases HO-1 Expression in ARPE-19 Cells, But Melanosomes Suppress the Increase When Light Is the Stressor

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Anna Pilat; Anja M. Herrnreiter; Christine M. B. Skumatz; Tadeusz Sarna; Janice M. Burke
TAGS: antioxidants, enzymes, melanosomes, proteins, oxidative stress, stress, stressor, phagocytosis
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):47-56. doi: https://doi.org/10.1167/iovs.12-11153

ARVO Annual Meeting Abstract March 2012

The Ratio of Melanosome to Lipofuscin Granule Number, Not Lipofuscin Content Alone, Determines the Susceptibility of Individual RPE Cells to Lethal Photic Stress in vitro

Mariusz Zareba; Tadeusz J. Sarna; Janice M. Burke

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4273. doi:

ARVO Annual Meeting Abstract March 2012

Oxidative Stress to ARPE-19 Cells by Treatment with Photosensitizers plus Light Decreases Protein Receptors that Mediate Outer Segment Phagocytosis

Magdalena M. Olchawa; Anja Herrnreiter; Christine Skumatz; Janice M. Burke; Tadeusz J. Sarna

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4775. doi:

ARVO Annual Meeting Abstract March 2012

Oxidative Stress Increases HO-1 in ARPE-19 Cells but Melanosomes Suppress the Increase when Light is the Stressor

Anna K. Pilat; Anja Herrnreiter; Christine Skumatz; Janice M. Burke; Tadeusz J. Sarna

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4776. doi:

ARVO Annual Meeting Abstract March 2012

Do Melanosomes Release or Bind Iron Ions inside RPE-Derived Cells?

Patrycja Kaczara; Anna K. Pilat; Anja Herrnreiter; Christine M. Skumatz; Tadeusz J. Sarna; Janice M. Burke

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4777. doi:

ARVO Annual Meeting Abstract April 2011

RPE Melanosomes Protect Cells against Non-Photic Stress

Mariusz Zareba; Patrycja Kaczara; Christine Skumatz; Tadeusz J. Sarna; Magdalena Olchawa; Anna Pilat; Janice M. Burke

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4424. doi:

Retinal Cell Biology April 2009

Sublethal Photic Stress and the Motility of RPE Phagosomes and Melanosomes

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Janice M. Burke; Mariusz Zareba
TAGS: cell motility, melanosomes, organelles, phagosomes, stress, granules, blue light
Invest. Ophthalmol. Vis. Sci.. 2009; 50(4):1940-1947. doi: https://doi.org/10.1167/iovs.08-2671

Biochemistry and Molecular Biology July 2008

Human RPE Melanosomes Protect from Photosensitized and Iron-Mediated Oxidation but Become Pro-oxidant in the Presence of Iron upon Photodegradation

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Bartosz Różanowski; Janice M. Burke; Michael E. Boulton; Tadeusz Sarna; Małgorzata Różanowska
TAGS: iron, melanins, melanosomes, oxidation, phototoxic dermatitis, oxidants, ions, granules, oxygen
Invest. Ophthalmol. Vis. Sci.. 2008; 49(7):2838-2847. doi: https://doi.org/10.1167/iovs.08-1700

Retinal Cell Biology August 2006

Fate of E-cadherin in Early RPE Cultures: Transient Accumulation of Truncated Peptides at Nonjunctional Sites

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Janice M. Burke; Jeehee Hong
TAGS: e-cadherin, peptides, proteins, antibodies
Invest. Ophthalmol. Vis. Sci.. 2006; 47(8):3635-3643. doi: https://doi.org/10.1167/iovs.06-0104

Retinal Cell Biology June 2006

Cell Phenotype in Normal Epithelial Cell Lines with High Endogenous N-Cadherin: Comparison of RPE to an MDCK Subclone

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Yong-Ha Youn; Jeehee Hong; Janice M. Burke
TAGS: cadherins, epithelial cells, n-cadherins, phenotype, proteins, clone cells, glycosylation, e-cadherin, tunicamycin
Invest. Ophthalmol. Vis. Sci.. 2006; 47(6):2675-2685. doi: https://doi.org/10.1167/iovs.05-1335

Biochemistry and Molecular Biology April 2004

Age-Related Changes in the Photoreactivity of Retinal Lipofuscin Granules: Role of Chloroform-Insoluble Components

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Małgorzata Różanowska; Anna Pawlak; Bartosz Różanowski; Christine Skumatz; Mariusz Zarȩba; Mike E. Boulton; Janice M. Burke; Tadeusz Sarna; John D. Simon
TAGS: chediak-higashi syndrome, granules, lipofuscin, oxygen, chloroform
Invest. Ophthalmol. Vis. Sci.. 2004; 45(4):1052-1060. doi: https://doi.org/10.1167/iovs.03-0277

Biochemistry and Molecular Biology July 2002

Photoreactivity of Aged Human RPE Melanosomes: A Comparison with Lipofuscin

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Małgorzata Różanowska; Witold Korytowski; Bartosz Różanowski; Christine Skumatz; Mike E. Boulton; Janice M. Burke; Tadeusz Sarna
TAGS: granules, hydrogen peroxide, lipofuscin, melanosomes, oxygen, pigment, blue light
Invest. Ophthalmol. Vis. Sci.. 2002; 43(7):2088-2096. doi:

Cornea December 2001

Maspin: Synthesis by Human Cornea and Regulation of In Vitro Stromal Cell Adhesion to Extracellular Matrix

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Chatri Ngamkitidechakul; Janice M. Burke; William J. O’Brien; Sally S. Twining
TAGS: adhesions, cornea, proteins, stromal cells, extracellular matrix, regulation, yeasts
Invest. Ophthalmol. Vis. Sci.. 2001; 42(13):3135-3141. doi:

Retinal Cell Biology September 2000

Time at Confluence for Human RPE Cells: Effects on the Adherens Junction and In Vitro Wound Closure

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Mayumi Kaida; Feng Cao; Christine M. B. Skumatz; Pamela E. Irving; Janice M. Burke
TAGS: actins, adherens junction, antibodies, cadherins, calcium, detergents, n-cadherins, proteins, retinal pigment cell, wound closure
Invest. Ophthalmol. Vis. Sci.. 2000; 41(10):3215-3224. doi:

Retinal Cell Biology June 2000

High Levels of E-/P-Cadherin: Correlation with Decreased Apical Polarity of Na/K ATPase in Bovine RPE Cells In Situ

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Janice M. Burke; Feng Cao; Pamela E. Irving
TAGS: cadherins, cattle, na(+)-k(+)-exchanging atpase, retinal pigment cell, ankyrins, polarity
Invest. Ophthalmol. Vis. Sci.. 2000; 41(7):1945-1952. doi:

Retinal Cell Biology November 1999

Expression of E-Cadherin by Human Retinal Pigment Epithelium: Delayed Expression In Vitro

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Janice M. Burke; Feng Cao; Pamela E. Irving; Christine M. B. Skumatz
TAGS: cadherins, e-cadherin, retinal pigment cell, proteins
Invest. Ophthalmol. Vis. Sci.. 1999; 40(12):2963-2970. doi:

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Nitroxide free radicals protect macular xanthophylls against chemical destruction (bleaching) during lipid peroxidation

Photic Injury to Cultured RPE Varies Among Individual Cells in Proportion to Their Endogenous Lipofuscin Content as Modulated by Their Melanosome Content

Photosensitized Oxidative Stress to ARPE-19 Cells Decreases Protein Receptors that Mediate Photoreceptor Outer Segment Phagocytosis

Oxidative Stress Increases HO-1 Expression in ARPE-19 Cells, But Melanosomes Suppress the Increase When Light Is the Stressor

The Ratio of Melanosome to Lipofuscin Granule Number, Not Lipofuscin Content Alone, Determines the Susceptibility of Individual RPE Cells to Lethal Photic Stress in vitro

Oxidative Stress to ARPE-19 Cells by Treatment with Photosensitizers plus Light Decreases Protein Receptors that Mediate Outer Segment Phagocytosis

Oxidative Stress Increases HO-1 in ARPE-19 Cells but Melanosomes Suppress the Increase when Light is the Stressor

Do Melanosomes Release or Bind Iron Ions inside RPE-Derived Cells?

RPE Melanosomes Protect Cells against Non-Photic Stress

Sublethal Photic Stress and the Motility of RPE Phagosomes and Melanosomes

Human RPE Melanosomes Protect from Photosensitized and Iron-Mediated Oxidation but Become Pro-oxidant in the Presence of Iron upon Photodegradation

Fate of E-cadherin in Early RPE Cultures: Transient Accumulation of Truncated Peptides at Nonjunctional Sites

Cell Phenotype in Normal Epithelial Cell Lines with High Endogenous N-Cadherin: Comparison of RPE to an MDCK Subclone

Age-Related Changes in the Photoreactivity of Retinal Lipofuscin Granules: Role of Chloroform-Insoluble Components

Photoreactivity of Aged Human RPE Melanosomes: A Comparison with Lipofuscin

Maspin: Synthesis by Human Cornea and Regulation of In Vitro Stromal Cell Adhesion to Extracellular Matrix

Time at Confluence for Human RPE Cells: Effects on the Adherens Junction and In Vitro Wound Closure

High Levels of E-/P-Cadherin: Correlation with Decreased Apical Polarity of Na/K ATPase in Bovine RPE Cells In Situ

Expression of E-Cadherin by Human Retinal Pigment Epithelium: Delayed Expression In Vitro

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