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Articles September 2020

Edge of Scotoma Sensitivity as a Microperimetry Clinical Trial End Point in USH2A Retinopathy

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Jason Charng; Tina M. Lamey; Jennifer A. Thompson; Terri L. McLaren; Mary S. Attia; Ian L. McAllister; Ian J. Constable; David A. Mackey; John N. De Roach; Fred K. Chen
TAGS: eye, retinal diseases, scotoma
Trans. Vis. Sci. Tech.. 2020; 9(10):9. doi: https://doi.org/10.1167/tvst.9.10.9

Includes: Supplemental Content

Articles June 2020

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds

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Jason Charng; Paul G. Sanfilippo; Mary S. Attia; Monika Dolliver; Sukanya Arunachalam; Avenell L. Chew; Evan N. Wong; David A. Mackey; Fred K. Chen
TAGS: eye, scotoma
Trans. Vis. Sci. Tech.. 2020; 9(7):19. doi: https://doi.org/10.1167/tvst.9.7.19

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Cross-sectional and longitudinal analyses of microperimetry in USH2A -related retinitis pigmentosa

Jason Charng; Tina Lamey; Jen Thompson; Terri Mclaren; Mary Attia; John De Roach; David A Mackey; Fred Kuanfu Chen

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3384. doi:

ARVO Annual Meeting Abstract July 2019

Transient pupillary light reflexes driven by foveal cones in CEP290- or in NPHP5- associated LCA-ciliopathies

Arun kumar Krishnan; Jason Charng; Samuel G Jacobson; Alejandro J Roman; Alexandra Garafalo; Alexander Sumaroka; Malgorzata Swider; Evelyn Semenov; Rebecca Sheplock; Elise Heon; Artur V Cideciyan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1833. doi:

Retina December 2018

Blue Cone Monochromacy Caused by the C203R Missense Mutation or Large Deletion Mutations

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Alexander Sumaroka; Alexandra V. Garafalo; Artur V. Cideciyan; Jason Charng; Alejandro J. Roman; Windy Choi; Supna Saxena; Valeryia Aksianiuk; Susanne Kohl; Bernd Wissinger; Samuel G. Jacobson
TAGS: genotype, missense mutation, mutation, retinal cone, cohort studies
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5762-5772. doi: https://doi.org/10.1167/iovs.18-25280

Retina September 2018

Progression in X-linked Retinitis Pigmentosa Due to ORF15-RPGR Mutations: Assessment of Localized Vision Changes Over 2 Years

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Artur V. Cideciyan; Jason Charng; Alejandro J. Roman; Rebecca Sheplock; Alexandra V. Garafalo; Elise Heon; Samuel G. Jacobson
TAGS: mutation, retinal cone, retinitis pigmentosa, rod photoreceptors, vision, x-linked inheritance, perimetry, gene therapy, visual fields
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4558-4566. doi: https://doi.org/10.1167/iovs.18-24931

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

AAV-mediated expression of X-linked Inhibitor of Apoptosis protects photoreceptors in two canine models of early onset RP

William A Beltran; Artur V Cideciyan; Simone Iwabe; Valerie Dufour; Jason Charng; Brianna Lisi; Jose-Manuel Guzman; Alireza Badiei; Catherine Tsilfidis; William W Hauswirth; Samuel G Jacobson; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4527. doi:

Retina October 2017

Imaging Lenticular Autofluorescence in Older Subjects

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Jason Charng; Rose Tan; Chi D. Luu; Sam Sadigh; Dwight Stambolian; Robyn H. Guymer; Samuel G. Jacobson; Artur V. Cideciyan
TAGS: autofluorescence, diagnostic imaging, lens (device), lens, crystalline, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):4940-4947. doi: https://doi.org/10.1167/iovs.17-22540

Retina June 2017

Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells

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Jason Charng; Samuel G. Jacobson; Elise Heon; Alejandro J. Roman; David B. McGuigan, III; Rebecca Sheplock; Mychajlo S. Kosyk; Malgorzata Swider; Artur V. Cideciyan
TAGS: blindness, luminance, photoreceptors, pupil, reflex, retinal ganglion cells
Invest. Ophthalmol. Vis. Sci.. 2017; 58(7):3215-3224. doi: https://doi.org/10.1167/iovs.17-21909

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Interocular Symmetry of Rod and Cone Topography in Human ORF15-RPGR -XLRP Disease Despite Large Intraretinal, Intrafamilial and Interfamilial Variation

Artur V Cideciyan; Jason Charng; Samuel G Jacobson; Alexander Sumaroka; Sharon B. Schwartz; Malgorzata Swider; Alejandro J Roman; Rebecca Sheplock; Manisha Anand; Marc C. Peden; Hemant Khanna; Elise Heon; Alan F. Wright; Anand Swaroop

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3232. doi:

ARVO Annual Meeting Abstract June 2017

Human Melanopic Pupillary Responses Isolated from Outer Retinal Photoreceptor Input in LCA Patients with Severe Vision Loss

Jason Charng; Samuel G Jacobson; Elise Heon; Alejandro J Roman; David B. McGuigan; Rebecca Sheplock; Mychajlo S. Kosyk; Artur V Cideciyan

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4135. doi:

Retina May 2017

Outcome Measures for Clinical Trials of Leber Congenital Amaurosis Caused by the Intronic Mutation in the CEP290 Gene

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Samuel G. Jacobson; Artur V. Cideciyan; Alexander Sumaroka; Alejandro J. Roman; Jason Charng; Monica Lu; Windy Choi; Rebecca Sheplock; Malgorzata Swider; Mychajlo S. Kosyk; Sharon B. Schwartz; Edwin M. Stone; Gerald A. Fishman
TAGS: cohort studies, eye, genes, introns, leber's amaurosis, mutation, outcome measures, questionnaires, vision, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2609-2622. doi: https://doi.org/10.1167/iovs.17-21560

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Comparative Measurements of Rod Function in Retinal Degenerations with Two-color Dark-adapted Perimetry

Artur V Cideciyan; Jason Charng; Malgorzata Swider; Rebecca Sheplock; David B McGuigan; Rodrigo Matsui; Alejandro J Roman; Sharon B Schwartz; Samuel G Jacobson

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):131. doi:

ARVO Annual Meeting Abstract September 2016

Fragile Maculas in Patients with Retinal Degeneration due to RPGR - ORF15 Mutations: Spatio-temporal Models of Disease Progression

Jason Charng; Malgorzata Swider; Rebecca Sheplock; Alexander Sumaroka; Alejandro J Roman; Marc Christopher Peden; Elise Heon; Sharon B Schwartz; Samuel G Jacobson; Artur V Cideciyan

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):156. doi:

Retina June 2016

Developing an Outcome Measure With High Luminance for Optogenetics Treatment of Severe Retinal Degenerations and for Gene Therapy of Cone Diseases

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Artur V. Cideciyan; Alejandro J. Roman; Samuel G. Jacobson; Boyuan Yan; Michele Pascolini; Jason Charng; Simone Pajaro; Sheila Nirenberg

Invest. Ophthalmol. Vis. Sci.. 2016; 57(7):3211-3221. doi: https://doi.org/10.1167/iovs.16-19586

ARVO Annual Meeting Abstract April 2014

Anesthesia usage confounds in vivo pharmacological studies using electrophysiology

Jason Charng; Zheng He; Algis J Vingrys; Bang V Bui; Rebecca L Fish; Rachel Gurrell; Christine T Nguyen

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6191. doi:

ARVO Annual Meeting Abstract March 2012

Longitudinal Stability Of Conscious And Anaesthetised Wireless Telemetry Electroretinography Recordings In Rats

Jason Charng; Zheng He; Algis J. Vingrys; Bang V. Bui; Rebecca L. Fish; Dewi Roberts; Rachel Gurrell; Christine T. Nguyen

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2466. doi:

ARVO Annual Meeting Abstract March 2012

Optimal Electrode Placement for Conscious Wireless Telemetric Electroretinography

Christine T. Nguyen; Jason Charng; Zheng He; Trung M. Dang; Rebecca L. Fish; Dewi Roberts; Rachel Gurrell; Algis J. Vingrys; Bang V. Bui

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2467. doi:

ARVO Annual Meeting Abstract March 2012

The Effect of Repeated Intracameral Injection on Young and Old Rat Eyes

Algis J. Vingrys; Jason Charng; Christine T. Nguyen; Andrew I. Jobling; Bang V. Bui

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):164. doi:

Retina November 2011

Age-Related Retinal Function Changes in Albino and Pigmented Rats

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Jason Charng; Christine T. O. Nguyen; Bang V. Bui; Algis J. Vingrys
TAGS: aging, albinism, electroretinography, photoreceptors, rats, rod photoreceptors, retinal cone
Invest. Ophthalmol. Vis. Sci.. 2011; 52(12):8891-8899. doi: https://doi.org/10.1167/iovs.11-7602

Includes: Supplemental Content

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Edge of Scotoma Sensitivity as a Microperimetry Clinical Trial End Point in USH2A Retinopathy

Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds

Cross-sectional and longitudinal analyses of microperimetry in USH2A -related retinitis pigmentosa

Transient pupillary light reflexes driven by foveal cones in CEP290- or in NPHP5- associated LCA-ciliopathies

Blue Cone Monochromacy Caused by the C203R Missense Mutation or Large Deletion Mutations

Progression in X-linked Retinitis Pigmentosa Due to ORF15-RPGR Mutations: Assessment of Localized Vision Changes Over 2 Years

AAV-mediated expression of X-linked Inhibitor of Apoptosis protects photoreceptors in two canine models of early onset RP

Imaging Lenticular Autofluorescence in Older Subjects

Pupillary Light Reflexes in Severe Photoreceptor Blindness Isolate the Melanopic Component of Intrinsically Photosensitive Retinal Ganglion Cells

Interocular Symmetry of Rod and Cone Topography in Human ORF15-RPGR -XLRP Disease Despite Large Intraretinal, Intrafamilial and Interfamilial Variation

Human Melanopic Pupillary Responses Isolated from Outer Retinal Photoreceptor Input in LCA Patients with Severe Vision Loss

Outcome Measures for Clinical Trials of Leber Congenital Amaurosis Caused by the Intronic Mutation in the CEP290 Gene

Comparative Measurements of Rod Function in Retinal Degenerations with Two-color Dark-adapted Perimetry

Fragile Maculas in Patients with Retinal Degeneration due to RPGR - ORF15 Mutations: Spatio-temporal Models of Disease Progression

Developing an Outcome Measure With High Luminance for Optogenetics Treatment of Severe Retinal Degenerations and for Gene Therapy of Cone Diseases

Anesthesia usage confounds in vivo pharmacological studies using electrophysiology

Longitudinal Stability Of Conscious And Anaesthetised Wireless Telemetry Electroretinography Recordings In Rats

Optimal Electrode Placement for Conscious Wireless Telemetric Electroretinography

The Effect of Repeated Intracameral Injection on Young and Old Rat Eyes

Age-Related Retinal Function Changes in Albino and Pigmented Rats

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