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ARVO Annual Meeting Abstract June 2025

Serum Insulin-like Growth Factor-1 and Neutrophil-to-lymphocyte ratio in Individuals with Diabetic Retinopathy (DR) and Diabetic Macular Edema (DME)

Nicholas Medawar; Akanksha Malepati; Ram Prasad; Sarbodeep Paul; Jason Neal Crosson; John Mason; Edmund Arthur; Edgar Ready V; Jason Floyd; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4834.

ARVO Annual Meeting Abstract June 2025

Immunomodulation by bone marrow (BM) cells expressing increased levels of angiotensin-converting enzyme 2 (ACE2) corrects diabetic retinopathy (DR) in type 1 diabetic (T1D) mice.

Ram Prasad; Jason Floyd; Bright Asare-Bediako; Dibyendu Chakraborty; Yvonne Adu-Rutledge; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1615.

ARVO Annual Meeting Abstract June 2024

Ile-Trp dipeptide prevents diabetic retinopathy via gut Indole/AhR/PXR signaling in type 2 diabetes

Ram Prasad; Yvonne Adu-Agyeiwaah; Edgar L Ready V; Sarbodeep Paul; Rati Sharma; Iuliia Dorofeeva; Jason Floyd; Aayush Rohella; Sergio Li Calzi; Bruce Stevens; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):844.

ARVO Annual Meeting Abstract June 2024

Oral alpha-cyclodextrin targets the gut-retinal axis and corrects diabetic retinopathy (DR) in a mouse model of type 2 diabetes (T2D).

Yvonne Adu-Agyeiwaah; Ram Prasad; Sergio Li Calzi; Bright Asare Bediako; Jason Floyd; Mariana D Dupont; Tim Florian Dorweiler; Cristiano Vieira; Irina A Pikuleva; Julia Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):836.

ARVO Annual Meeting Abstract June 2024

The calvarium bone marrow responds to acute retinal injury and is resilient to chronic diabetes compared to long bone marrow.

Sergio Li Calzi; Bright Asare-Bediako; Ram Prasad; Yvonne Adu-Agyeiwaah; Robert F Rosencrans; Jason Floyd; Denise Stanford; Anna Lin; Todd A Lydic; Michael Boulton; Julia Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):325.

ARVO Annual Meeting Abstract June 2024

An engineered probiotic expressing Ang1-7 minimizes the risk of developing diabetic retinopathy in db/db mice

Sarbodeep Paul; Ram Prasad; Yvonne Adu-Agyeiwaah; Edgar L Ready V; Rati Sharma; Iuliia Dorofeeva; Jason Floyd; Aayush Rohella; Sergio Li Calzi; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):323.

ARVO Annual Meeting Abstract June 2023

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Ram Prasad; Jason Floyd; Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Sergio Li Calzi; Dibyendu Chakraborty; Angela Harbour; Aayush Rohella; Irina A Pikuleva; Julia V. Busik; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):938.

ARVO Annual Meeting Abstract June 2023

Oral alpha-cyclodextrin reverses cholesterol-crystal-induced retinal pathology in a rodent model of type 2 diabetes (T2D).

Yvonne Adu-Agyeiwaah; Bright Asare-Bediako; Jason Floyd; Mariana D DuPont; Cristiano Vieira; Ram Prasad; Sergio Li Calzi; Irina A Pikuleva; Julia V. Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1834.

ARVO Annual Meeting Abstract June 2023

Characterization of Circulating Immune Cell Subsets in Subjects with DR and DME

Shambhavi Anshumali; Mariana D DuPont; Jason Floyd; Kara Kichler; John Mason; Jason Neal Crosson; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):3905.

Retina April 2023

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

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Yvonne Adu-Agyeiwaah; Cristiano P. Vieira; Bright Asare-Bediako; Sergio Li Calzi; Mariana DuPont; Jason Floyd; Sanford Boye; Vince Chiodo; Julia V. Busik; Maria B. Grant
TAGS: diabetes mellitus, diabetes mellitus, type 2, diabetic retinopathy, intravitreal injections, mice, retina, blood capillaries, inflammation, hypoxia
Trans. Vis. Sci. Tech.. 2023; 12(4):20. https://doi.org/10.1167/tvst.12.4.20

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Maintenance of intestinal ACE2 minimizes the risk of developing diabetic retinopathy in type 1 diabetes

Ram Prasad; Jason Floyd; Bright Asare-Bediako; Dibyendu Chakraborty; Yvonne Adu-Agyeiwaah; Angela Harbour; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2309.

ARVO Annual Meeting Abstract June 2022

DIFFERENTIAL RECUITMENT OF HEMATOPOIETIC CELLS INTO THE INJURED RPE/CHOROID

Bright Asare-Bediako; Sergio Li Calzi; Yvonne Adu-Agyeiwaah; Jason Floyd; Mariana D DuPont; Maria Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3025 – F0396.

ARVO Annual Meeting Abstract June 2022

Oral administration of alpha-cyclodextrin reverses diabetic retinopathy in db/db mice

Yvonne Adu-Agyeiwaah; Sandra S Hammer; Cristiano P. Vieira; Bright Asare-Bediako; Jason Floyd; Mariana D DuPont; Ram Prasad; Sergio Li Calzi; Julia V Busik; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3591 – A0046.

Immunology and Microbiology January 2022

Microbial Signatures in The Rodent Eyes With Retinal Dysfunction and Diabetic Retinopathy

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Ram Prasad; Bright Asare-Bediko; Angela Harbour; Jason L Floyd; Dibyendu Chakraborty; Yaqian Duan; Regina Lamendella; Justin Wright; Maria B. Grant
TAGS: diabetic retinopathy, eye, mice, microorganisms, plasma, retina, retinal diseases, pathophysiology, diabetes mellitus, rna, ribosomal, 16s
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):5. https://doi.org/10.1167/iovs.63.1.5

ARVO Annual Meeting Abstract June 2020

Oral administration of engineered probiotic prevents gut dysbiosis in type 1 diabetes and alleviates diabetic retinopathy (DR)

Ram Prasad; Jason L. Floyd; DIBYENDU CHAKRABORTY; Bright Asare-Bediako; Yvonne Adu-Agyeiwaah; Sergio Li Calzi; Robert F. Rosencrans; Chao Huang; Mariana DuPont; Sunil K Noothi; Qiuhong Li; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1169.

ARVO Annual Meeting Abstract July 2019

Gut microbiota intensifies retinal vascular defects by targeting adherens junction protein p120-catenin in angiotensin converting enzyme 2 (ACE2) deficient type 1 diabetes (T1D)

Ram Prasad; Yaqian Duan; Gopalkrishna Sreejit; Jason L. Floyd; Baskaran Athmanathan; Prabhakara R Nagareddy; Maria B Grant

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):977.

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Serum Insulin-like Growth Factor-1 and Neutrophil-to-lymphocyte ratio in Individuals with Diabetic Retinopathy (DR) and Diabetic Macular Edema (DME)

Immunomodulation by bone marrow (BM) cells expressing increased levels of angiotensin-converting enzyme 2 (ACE2) corrects diabetic retinopathy (DR) in type 1 diabetic (T1D) mice.

Ile-Trp dipeptide prevents diabetic retinopathy via gut Indole/AhR/PXR signaling in type 2 diabetes

Oral alpha-cyclodextrin targets the gut-retinal axis and corrects diabetic retinopathy (DR) in a mouse model of type 2 diabetes (T2D).

The calvarium bone marrow responds to acute retinal injury and is resilient to chronic diabetes compared to long bone marrow.

An engineered probiotic expressing Ang1-7 minimizes the risk of developing diabetic retinopathy in db/db mice

LP-ACE2 attenuates diabetic visual impairment by improving gut barrier integrity and intestinal lymphatics in type 1 diabetes

Oral alpha-cyclodextrin reverses cholesterol-crystal-induced retinal pathology in a rodent model of type 2 diabetes (T2D).

Characterization of Circulating Immune Cell Subsets in Subjects with DR and DME

Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

Maintenance of intestinal ACE2 minimizes the risk of developing diabetic retinopathy in type 1 diabetes

DIFFERENTIAL RECUITMENT OF HEMATOPOIETIC CELLS INTO THE INJURED RPE/CHOROID

Oral administration of alpha-cyclodextrin reverses diabetic retinopathy in db/db mice

Microbial Signatures in The Rodent Eyes With Retinal Dysfunction and Diabetic Retinopathy

Oral administration of engineered probiotic prevents gut dysbiosis in type 1 diabetes and alleviates diabetic retinopathy (DR)

Gut microbiota intensifies retinal vascular defects by targeting adherens junction protein p120-catenin in angiotensin converting enzyme 2 (ACE2) deficient type 1 diabetes (T1D)

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