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ARVO Annual Meeting Abstract June 2020

Fenofibrate Prevents Iron Induced Activation of Canonical Wnt/β-Catenin and Oxidative Stress Signaling in the Retina

Jaya P Gnana-Prakasam; Ashok Mandala; Austin Armstrong; Jiyao Zhu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):683. doi:

ARVO Annual Meeting Abstract July 2019

Iron Regulates Canonical Wnt/β-catenin Signaling in Retina

Jaya P Gnana-Prakasam; Ashok Mandala

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5980. doi:

ARVO Annual Meeting Abstract September 2016

Retinal Iron Overload during Diabetic Retinopathy Accelerates Ganglion Cell Death

Jaya P Gnana-Prakasam; Kapil Chaudhary; Wanwisa Promsote; Sylvia B Smith; Vadivel Ganapathy; Pamela M Martin; Alan Saul

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):751. doi:

ARVO Annual Meeting Abstract June 2015

Mitochondrial histone deacetylase Sirt3 as a regulator of iron homeostasis and metabolite receptors Gpr91 and Gpr81 in retina

Vadivel Ganapathy; Pachiappan Arjunan; Jaya Pranava Gnana Prakasam; Sylvia B Smith; Pamela M Martin; James and Jean Culver Vision Discovery Institute, The Medical College of Georgia at Georgia Regents University

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):59. doi:

ARVO Annual Meeting Abstract June 2015

Expression of Iron Regulatory Proteins in Diabetic Retina

Jaya Pranava Gnana-Prakasam; Sudha Ananth; Kapil Chaudhary; Vadivel Ganapathy; Sylvia B Smith; Pamela M Martin

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):154. doi:

Retinal Cell Biology June 2014

Deletion of Hemojuvelin, an Iron-Regulatory Protein, in Mice Results in Abnormal Angiogenesis and Vasculogenesis in Retina Along With Reactive Gliosis

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Amany Tawfik; Jaya P. Gnana-Prakasam; Sylvia B. Smith; Vadivel Ganapathy
TAGS: angiogenesis, gliosis, hfe2 gene, iron, mice, proteins, retina, retinal vasculature
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3616-3625. doi: https://doi.org/10.1167/iovs.13-13677

ARVO Annual Meeting Abstract April 2014

Expression of the lactate receptor Gpr81 in mouse retina and its regulation in mouse models of hemochromatosis and diabetes

Vadivel Ganapathy; Pachiappan Arjunan; Jaya P Gnana-Prakasam; Sudha Ananth; Pamela M Martin; Sylvia B Smith; James and Jean Culver Vision Discovery Institute

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2954. doi:

ARVO Annual Meeting Abstract April 2014

Gpr91, a pro-angiogenic receptor for succinate, is upregulated in hemojuvelin-null mouse retina via increased BMP6 signaling

Pachiappan Arjunan; Jaya P Gnana-Prakasam; Sudha Ananth; Michelle A Romej; Rajalakshmi Veeranan-Karmegam; Sylvia B Smith; Vadivel Ganapathy; James and Jean Culver Vision Discovery Institute

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):6337. doi:

ARVO Annual Meeting Abstract April 2014

Prevalence of HFE mutation in age-related macular degeneration (AMD)

Abu-Bakar Zafar; Vadivel Ganapathy; Brad Snead; Michael Wildes; Jaya P Gnana-Prakasam; Julian J Nussbaum

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2224. doi:

Retina January 2013

Loss of Hfe Leads to Progression of Tumor Phenotype in Primary Retinal Pigment Epithelial Cells

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Jaya P. Gnana-Prakasam; Rajalakshmi Veeranan-Karmegam; Veena Coothankandaswamy; Sushma K. Reddy; Pamela M. Martin; Muthusamy Thangaraju; Sylvia B. Smith; Vadivel Ganapathy
TAGS: neoplasms, retinal pigment cell, phenotype
Invest. Ophthalmol. Vis. Sci.. 2013; 54(1):63-71. doi: https://doi.org/10.1167/iovs.12-10312

ARVO Annual Meeting Abstract March 2012

The Anti-inflammatory Receptor GPR109A Regulates Angiopoeitin-like-4 (ANGPTL4) Expression in Retina: Potential New Link Between Regulation of Inflammatory and Angiogenic Signaling Mechanisms in Diabetic Retina

Deeksha Gambhir; Sudha Ananth; Rajalakshmi Veeranan-Karmegam; Jaya P. Gnana Prakasam; Vadivel Ganapathy; Pamela M. Martin

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):5777. doi:

ARVO Annual Meeting Abstract March 2012

Expression of Matriptase2 (TMPRSS6), a Proteolytic Regulator of Iron Homeostasis, in Retina, and Expression of Iron-regulatory Genes in Matriptase2-null Mouse Retina

Brooke R. Bozard; Sudha Ananth; Jaya P. Gnana-Prakasam; Pamela M. Martin; Sylvia B. Smith; Vadivel Ganapathy

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):4296. doi:

ARVO Annual Meeting Abstract March 2012

Loss of Hfe Leads to Progression of Tumor Phenotype in Primary Retinal Pigment Epithelial Cells

Jaya Pranava Gnana Prakasam; Rajalakshmi Veeranan-Karmegam; Veena Coothankandaswamy; Sushma K. Reddy; Pamela M. Martin; Muthusamy Thangaraju; Sylvia B. Smith; Vadivel Ganapathy

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):6548. doi:

ARVO Annual Meeting Abstract March 2012

Cystathionine Beta Synthase (cbs) Expression In Mouse Retina

Shanu Markand; Amany M. Tawfik; Yonju Ha; Jaya Gnana-Prakasam; Cory Williams; Srinivas Sonne; Vadivel Ganapathy; Sylvia B. Smith

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3966. doi:

Retinal Cell Biology November 2011

Polarized Distribution of Heme Transporters in Retinal Pigment Epithelium and Their Regulation in the Iron-Overload Disease Hemochromatosis

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Jaya P. Gnana-Prakasam; Sushma K. Reddy; Rajalakshmi Veeranan-Karmegam; Sylvia B. Smith; Pamela M. Martin; Vadivel Ganapathy
TAGS: heme, hemochromatosis, iron overload, membrane transport proteins, mice, regulation, retina, retinal pigment cell, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2011; 52(12):9279-9286. doi: https://doi.org/10.1167/iovs.11-8264

Retina May 2011

Expression and Iron-Dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium

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Jaya P. Gnana-Prakasam; Sudha Ananth; Puttur D. Prasad; Ming Zhang; Sally S. Atherton; Pamela M. Martin; Sylvia B. Smith; Vadivel Ganapathy
TAGS: cytomegalovirus infections, iron, mice, regulation, retina, retinal pigment epithelium, succinates, retinal pigment cell, vascular endothelial growth factor a, hemochromatosis
Invest. Ophthalmol. Vis. Sci.. 2011; 52(6):3751-3758. doi: https://doi.org/10.1167/iovs.10-6722

ARVO Annual Meeting Abstract April 2011

Regulation Of Proton-coupled Folate Transporter (PCFT) By Fumaric Acid Esters

Brooke R. Bozard; Paresh Chothe; Jaya P. Gnana-Prakasam; Rebecca Nalloor; Yonju Ha; Pamela M. Martin; Vadivel Ganapathy; Sylvia B. Smith

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1852. doi:

ARVO Annual Meeting Abstract April 2011

Transport Of Hepcidin, An Iron-regulatory Peptide Hormone, Into Retinal Pigment Epithelial Cells

Vadivel Ganapathy; Paresh Chothe; Jaya P. Gnana-Prakasam; Ram Kannan; David R. Hinton; Sylvia B. Smith; Pamela M. Martin

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3333. doi:

ARVO Annual Meeting Abstract April 2011

Expression and Iron-dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium

Jaya Pranava Gnana Prakasam; Sudha Ananth; Puttur D. Prasad; Ming Zhang; Sally S. Atherton; Pamela M. Martin; Sylvia B. Smith; Vadivel Ganapathy

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):929. doi:

Physiology and Pharmacology January 2010

Identification of a Novel Sodium-Coupled Oligopeptide Transporter (SOPT2) in Mouse and Human Retinal Pigment Epithelial Cells

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Paresh P. Chothe; Santoshanand V. Thakkar; Jaya P. Gnana-Prakasam; Sudha Ananth; David R. Hinton; Ram Kannan; Sylvia B. Smith; Pamela M. Martin; Vadivel Ganapathy
TAGS: enkephalin, leucine-2-alanine, membrane transport proteins, mice, oligopeptides, opioid peptide, peptides, retinal pigment cell, sodium, fetus, biological transport
Invest. Ophthalmol. Vis. Sci.. 2010; 51(1):413-420. doi: https://doi.org/10.1167/iovs.09-4048

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Fenofibrate Prevents Iron Induced Activation of Canonical Wnt/β-Catenin and Oxidative Stress Signaling in the Retina

Iron Regulates Canonical Wnt/β-catenin Signaling in Retina

Retinal Iron Overload during Diabetic Retinopathy Accelerates Ganglion Cell Death

Mitochondrial histone deacetylase Sirt3 as a regulator of iron homeostasis and metabolite receptors Gpr91 and Gpr81 in retina

Expression of Iron Regulatory Proteins in Diabetic Retina

Deletion of Hemojuvelin, an Iron-Regulatory Protein, in Mice Results in Abnormal Angiogenesis and Vasculogenesis in Retina Along With Reactive Gliosis

Expression of the lactate receptor Gpr81 in mouse retina and its regulation in mouse models of hemochromatosis and diabetes

Gpr91, a pro-angiogenic receptor for succinate, is upregulated in hemojuvelin-null mouse retina via increased BMP6 signaling

Prevalence of HFE mutation in age-related macular degeneration (AMD)

Loss of Hfe Leads to Progression of Tumor Phenotype in Primary Retinal Pigment Epithelial Cells

The Anti-inflammatory Receptor GPR109A Regulates Angiopoeitin-like-4 (ANGPTL4) Expression in Retina: Potential New Link Between Regulation of Inflammatory and Angiogenic Signaling Mechanisms in Diabetic Retina

Expression of Matriptase2 (TMPRSS6), a Proteolytic Regulator of Iron Homeostasis, in Retina, and Expression of Iron-regulatory Genes in Matriptase2-null Mouse Retina

Loss of Hfe Leads to Progression of Tumor Phenotype in Primary Retinal Pigment Epithelial Cells

Cystathionine Beta Synthase (cbs) Expression In Mouse Retina

Polarized Distribution of Heme Transporters in Retinal Pigment Epithelium and Their Regulation in the Iron-Overload Disease Hemochromatosis

Expression and Iron-Dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium

Regulation Of Proton-coupled Folate Transporter (PCFT) By Fumaric Acid Esters

Transport Of Hepcidin, An Iron-regulatory Peptide Hormone, Into Retinal Pigment Epithelial Cells

Expression and Iron-dependent Regulation of Succinate Receptor GPR91 in Retinal Pigment Epithelium

Identification of a Novel Sodium-Coupled Oligopeptide Transporter (SOPT2) in Mouse and Human Retinal Pigment Epithelial Cells

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