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Clinical and Epidemiologic Research March 2025

NLRP3 Activation With Bisphosphonate Use and the Risk of Incident Age-Related Macular Degeneration

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Joseph Magagnoli; Tammy Cummings; James W. Hardin; S. Scott Sutton; Jayakrishna Ambati
TAGS: age-related macular degeneration, bisphosphonates, nlr family, pyrin domain-containing 3 protein
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):32. https://doi.org/10.1167/iovs.66.3.32

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

EFFECT OF ORAL LAMIVUDINE VERSUS PLACEBO IN DIABETIC MACULAR EDEMA: A RANDOMIZED CLINICAL TRIAL

Felipe Pereira; Joseph Magagnoli; Meenakshi Ambati; Talita Fernandes de Oliveira; Juliana Angélica Estevão de Oliveira; Vinicius Oliveira Pequero; Lucas Zago Ribeiro; Dante Akira Kondo Kuroiwa; Fernando Korn Malerbi; Sergio Atala Dib; Nilva Bueno Moraes; Michel Eid Farah; Eduardo Buchele Rodrigues; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4885.

ARVO Annual Meeting Abstract June 2024

Hemodynamic shear stress alters the transcriptional profile of choroidal endothelium

Joey Olivieri; Bradley D Gelfand; Jayakrishna Ambati; Charles Preston; Uriel Kim

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4961.

ARVO Annual Meeting Abstract June 2024

Sex differences in angiogenesis inhibition by human IgG1 antibodies

Bradley D Gelfand; Dionne A Argyle; Felipe Pereira; Shao-bin Wang; Roshni Dholkawala; Yohei Arai; Kenneth Walsh; Arthur Arnold; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4958.

ARVO Annual Meeting Abstract June 2023

Kamuvudine-9 protects retinal structure and function in a novel model of experimental rhegmatogenous retinal detachment

Claire C. Thomas; Peirong Huang; Kameshwari Ambati; Siddharth Narendran; Felipe Pereira; Ivana Apicella; Xiaoyu Cai; Ryan D. Makin; Praveen Yerramothu; Yosuke Nagasaka; Shao-bin Wang; Ayami Nagasaka; Roshni Dholkawala; Bradley D. Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4888.

Retina May 2023

Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment

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Peirong Huang; Claire C. Thomas; Kameshwari Ambati; Roshni Dholkawala; Ayami Nagasaka; Praveen Yerramothu; Siddharth Narendran; Felipe Pereira; Yosuke Nagasaka; Ivana Apicella; Xiaoyu Cai; Ryan D. Makin; Joseph Magagnoli; Cliff I. Stains; Ruwen Yin; Shao-bin Wang; Bradley D. Gelfand; Jayakrishna Ambati
TAGS: retina, retinal detachment, rhegmatogenous retinal detachment, mice
Invest. Ophthalmol. Vis. Sci.. 2023; 64(5):3. https://doi.org/10.1167/iovs.64.5.3

ARVO Annual Meeting Abstract June 2022

Sexual dimorphism in antigen-independent angiogenesis inhibition of IgG1 antibodies

Dionne Argyle; Felipe Pereira; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):275 – F0320.

ARVO Annual Meeting Abstract June 2022

NLRP3 inflammasome activation affects neuroretinal function in diabetic retinopathy

Xiaoyu Cai; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):948 – A0417.

Articles March 2022

The Learning Curve of Murine Subretinal Injection Among Clinically Trained Ophthalmic Surgeons

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Peirong Huang; Siddharth Narendran; Felipe Pereira; Shinichi Fukuda; Yosuke Nagasaka; Ivana Apicella; Praveen Yerramothu; Kenneth M. Marion; Xiaoyu Cai; Srinivas R. Sadda; Bradley D. Gelfand; Jayakrishna Ambati
TAGS: eye, injections, learning, mice, serotonin uptake inhibitors, surgeons
Trans. Vis. Sci. Tech.. 2022; 11(3):13. https://doi.org/10.1167/tvst.11.3.13

ARVO Annual Meeting Abstract June 2021

Genetic ablation of PAD4 in the Accelerated Mouse Model of AMD Results in Reduced Citrullinated Products

Sarah Ilona Palko; Nicholas Saba; Benjamin D Nicholas; Yosuke Nagasaka; Jayakrishna Ambati; Bradley D Gelfand; Akihito Ishigami; Paola Bargagna-Mohan; Royce Mohan

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2726.

Retina August 2020

A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration

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Siddharth Narendran; Felipe Pereira; Praveen Yerramothu; Ivana Apicella; Shao-bin Wang; Akhil Varshney; Kirstie L. Baker; Kenneth M. Marion; Meenakshi Ambati; Vidya L. Ambati; Kameshwari Ambati; Srinivas R. Sadda; Bradley D. Gelfand; Jayakrishna Ambati
TAGS: atrophy, choroidal neovascularization, metabolites, rna, tissue degeneration, zidovudine, epithelium, lasers
Invest. Ophthalmol. Vis. Sci.. 2020; 61(10):4. https://doi.org/10.1167/iovs.61.10.4

ARVO Annual Meeting Abstract June 2020

PAD4 in the Accelerated Mouse Model of AMD and Human AMD

Sarah Ilona Palko; Nicholas Saba; Humza Zaidi; Benjamin Nicholas; Yosuke Nagasaka; Jayakrishna Ambati; Bradley Gelfand; Paola Bargagna-Mohan; Royce Mohan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3689.

ARVO Annual Meeting Abstract June 2020

Sex determines the off-target effects of Bevacizumab (Avastin) in mouse models

Dionne Argyle; Felipe Pereira; Ivana Apicella; Nagaraj Kerur; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4346.

ARVO Annual Meeting Abstract June 2020

Voluntary exercise attenuates choroidal neovascularization in mice

Ryan Daniel Makin; Dionne Argyle; Yosuke Nagasaka; Shuichiro Hirahara; Nagaraj Kerur; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5392.

ARVO Annual Meeting Abstract June 2020

Alu RNA exacerbates experimental choroidal neovascularization via an inflammasome-dependent pathway

Felipe Pereira; Ivana Apicella; Ryan Makin; Younghee Kim; Charles Wright; Tetsuhiro Yasuma; Reo Yasuma; Shuichiro Hirahara; Shinichi Fukuda; Siddharth Narendran; Romulo Albuquerque; Benjamin Fowler; Nagaraj Kerur; Jayakrishna Ambati; Bradley Gelfand

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5394.

Retinal Cell Biology May 2020

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice

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Ryan D. Makin; Dionne Argyle; Shuichiro Hirahara; Yosuke Nagasaka; Mei Zhang; Zhen Yan; Nagaraj Kerur; Jayakrishna Ambati; Bradley D. Gelfand
TAGS: choroidal neovascularization, exercise, mice
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):52. https://doi.org/10.1167/iovs.61.5.52

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Multifarious evidence for NLRP3 inflammasome expression and activation in retinal pigment epithelium

Ivana Apicella; Shinichi Fukuda; Shuichiro Hirahara; Shaobin Wang; Siddharth Narendran; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):765.

ARVO Annual Meeting Abstract July 2019

Title: Soluble oligomeric Amyloid-β induced retinal pigment epithelial degeneration requires non-canonical inflammsome activation

Siddharth Narendran; DAIPAYAN BANERJEE; Ivana Apicella; Shaobin Wang; Akhil Varshney; Shinichi Fukuda; Nagaraj Kerur; Bradley Gelfand; Jayakrishna Ambati

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):990.

ARVO Annual Meeting Abstract July 2019

TELOMERASE IN CHOROIDAL NEOVASCULARIZATION

Nagaraj Kerur; Jayakrishna Ambati; Shaobin Wang; DAIPAYAN BANERJEE; Shuichiro Hirahara; Eric Odermatt

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4319.

Retinal Cell Biology December 2018

RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes

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Ryan D. Makin; Ivana Apicella; Yosuke Nagasaka; Hiroki Kaneko; Stephen D. Turner; Nagaraj Kerur; Jayakrishna Ambati; Bradley D. Gelfand
TAGS: endothelial cells, endothelium, phenotype
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5795-5802. https://doi.org/10.1167/iovs.18-25215

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NLRP3 Activation With Bisphosphonate Use and the Risk of Incident Age-Related Macular Degeneration

EFFECT OF ORAL LAMIVUDINE VERSUS PLACEBO IN DIABETIC MACULAR EDEMA: A RANDOMIZED CLINICAL TRIAL

Hemodynamic shear stress alters the transcriptional profile of choroidal endothelium

Sex differences in angiogenesis inhibition by human IgG1 antibodies

Kamuvudine-9 protects retinal structure and function in a novel model of experimental rhegmatogenous retinal detachment

Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment

Sexual dimorphism in antigen-independent angiogenesis inhibition of IgG1 antibodies

NLRP3 inflammasome activation affects neuroretinal function in diabetic retinopathy

The Learning Curve of Murine Subretinal Injection Among Clinically Trained Ophthalmic Surgeons

Genetic ablation of PAD4 in the Accelerated Mouse Model of AMD Results in Reduced Citrullinated Products

A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration

PAD4 in the Accelerated Mouse Model of AMD and Human AMD

Sex determines the off-target effects of Bevacizumab (Avastin) in mouse models

Voluntary exercise attenuates choroidal neovascularization in mice

Alu RNA exacerbates experimental choroidal neovascularization via an inflammasome-dependent pathway

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice

Multifarious evidence for NLRP3 inflammasome expression and activation in retinal pigment epithelium

Title: Soluble oligomeric Amyloid-β induced retinal pigment epithelial degeneration requires non-canonical inflammsome activation

TELOMERASE IN CHOROIDAL NEOVASCULARIZATION

RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes

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