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ARVO Annual Meeting Abstract June 2023

Mobility task shows rescue of scotopic vision in a swine model for autosomal dominant Retinitis Pigmentosa after treatment with the meganuclease Rho 1-2

Kautuk Kamboj; Jack E. Feist; Francesca Barone; Gita Jaikumar; Archana Jalligampala; Wei Wang; Jeff Smith; Dave Morris; Jantz Derek; Victor Bartsevich; Kristi Viles; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5240.

ARVO Annual Meeting Abstract June 2023

Rod and cone structure and function decline in a humanized mouse model of P23H Rhodopsin Autosomal Dominant Retinitis Pigmentosa (adRP)

Mattia Di Paolo; Olivia N Jacobs; Kiersten Elyse Frye; Smith Jeff; Dave Morris; Jantz Derek; Victor Bartsevich; Dale Cowley; Kristi Viles; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5210.

ARVO Annual Meeting Abstract June 2022

Successful late-stage disease treatment of P23H human RHO (hRHO) using ARCUS nuclease gene editing in a pig model of Autosomal Dominant Retinitis Pigmentosa (adRP)

Archana Jalligampala; Jennifer M. Noel; Olivia Noelle Jacobs; Alec Lynn Bradley; Wei Wang; Maha Haleem Jabbar; Nazarul Hasan; Joseph Prestigiacomo; Jeff Smith; Victor Bartsevich; Kristi Viles; Derek Jantz; Maureen Ann McCall

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1107.

ARVO Annual Meeting Abstract June 2022

Characterization of a Humanized Mouse Model of P23H Rhodopsin Autosomal Dominant Retinitis Pigmentosa (adRP)

Maureen A McCall; Olivia N Jacobs; Nazarul Hasan; Jeff Smith; Derek Jantz; Victor Bartsevich; Dale Cowley; Kristi Viles

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2607 – F0490.

ARVO Annual Meeting Abstract June 2021

Rho 1-2 meganuclease, an allele-specific gene-editing therapy, rejuvenates rod photoreceptor structure and function in a pig model of autosomal dominant Retinitis Pigmentosa (adRP).

archana jalligampala; Jennifer Noel; James W Fransen; Wei Wang; Maha Jabbar; Nazarul Hasan; Gobinda Pangeni; Bhubanananda Sahu; Whitney Lewis; Jeff Smith; Victor Bartsevich; Kristi Viles; Derek Jantz; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1478.

ARVO Annual Meeting Abstract June 2020

Allele-specific Homing Endonuclease (HE) Gene Editing Induces Rod Function in a P23H Transgenic Swine Model of Retinitis Pigmentosa

James W Fransen; archana jalligampala; Jennifer Noel; Wei Wang; Jeff Smith; Victor Bartsevich; Kristi Viles; Maureen A McCall

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1915.

ARVO Annual Meeting Abstract July 2019

Allele-specific Gene Editing Induces Rod Function in a Transgenic Swine Model of Autosomal Dominant Retinitis Pigmentosa

Maureen A McCall; Archana Jalligampala; gobinda Pangeni; Maha Jabbar; Henry J Kaplan; Wei Wang; Bhubanananda Sahu; Jon E Chatterton; Jeff Smith; Victor Bartsevich; Kristi Viles

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4229.

ARVO Annual Meeting Abstract June 2017

Allele-specific gene editing for the treatment of autosomal dominant Retinitis Pigmentosa

Gene Liau; Kollu Nageswara Rao; Victor V Bartsevich; Jeff Smith; Derek Jantz; Matthew Hirsch

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4473.

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