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ARVO Imaging in the Eye Conference Abstract August 2019

Molecular Landscape of the Human Macula by High Resolution Imaging Mass Spectrometry

Kevin Schey; David MG Anderson; Kate H. McKinney; Jeffrey D Messinger; N. Heath Patterson; Jeffrey M. Spraggins; Christine Curcio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(11):010. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2019

Migration patterns of intraretinal retinal pigment epithelium (RPE) in non-neovascular age-related macular degeneration (nnAMD)

Belinda Leong; KENNETH R SLOAN; Jeffrey D Messinger; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3453. doi: https://doi.org/

Retina June 2019

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

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J. Alan Gambril; Kenneth R. Sloan; Thomas A. Swain; Carrie Huisingh; Anna V. Zarubina; Jeffrey D. Messinger; Thomas Ach; Christine A. Curcio
TAGS: age-related macular degeneration, autofluorescence, phenotype, retinal pigment epithelium, diagnostic imaging, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2481-2493. doi: https://doi.org/10.1167/iovs.19-26949

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Phenotypes of Retinal Pigment Epithelium (RPE) Autofluorescence (AF) and Morphology in Donor Eyes with Age-Related Macular Degeneration (AMD)

John Alan Gambril; Kenneth R Sloan; Carrie E Huisingh; Jeffrey D Messinger; Thomas Ach; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2437. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Photoreceptor (PR) degeneration, gliosis, and relation to supporting tissues in geographic atrophy (GA) of age-related macular degeneration (AMD)

Miaoling Li; Carrie Huisingh; Jeffrey D Messinger; Rosa Dolz-Marco; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2624. doi: https://doi.org/

ARVO Annual Meeting Abstract July 2018

Optimized human ocular tissue recovery and ex vivo multimodal imaging (MMI) for research in age-related macular degeneration (AMD)

Jeffrey D Messinger; James KImble; Alan Blake; K Bailey Freund; Theodore Smith; Thomas Ach; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3237. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2017

Organelle subclasses in human retinal pigment epithelium (RPE) in younger and older eyes seen with 3-dimensional serial block face scanning electron microscopy (3D SBFSEM)

Tamara Jasmin Jasmin Mittermueller; Jeffrey D Messinger; Kenneth R Sloan; Alexandra Stephanie Weinhandl; Emily Benson; Grahame J Kidd; Ursula Schmidt-Erfurth; Christine Curcio; Andreas Pollreisz

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):366. doi: https://doi.org/

Retinal Cell Biology February 2017

Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

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Matthew G. Pilgrim; Imre Lengyel; Antonio Lanzirotti; Matt Newville; Sarah Fearn; Eszter Emri; Jonathan C. Knowles; Jeffrey D. Messinger; Russell W. Read; Clyde Guidry; Christine A. Curcio
TAGS: cell culture techniques, immunohistochemistry, diffuse idiopathic skeletal hyperostosis, drusen, epithelium, durapatite, hydroxyapatites, pigment, spectrometry, mass, secondary ion, suidae
Invest. Ophthalmol. Vis. Sci.. 2017; 58(2):708-719. doi: https://doi.org/10.1167/iovs.16-21060

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Histological stages of subretinal drusenoid deposits (SDD) in eyes with age-related macular degeneration (AMD)

Christine A Curcio; Jeffrey D Messinger; Yuhua Zhang; David Neely; K Bailey Freund; Richard F Spaide

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

A primary retinal pigment epithelial (RPE) cell culture model produces lipid- and hydroxyapatite-rich extracellular deposits characteristic of early stage age-related macular degeneration

Matthew Glynn Pilgrim; Antonio Lanzirotti; Matt Newville; Sarah Fearn; Jonathan Knowles; Jeffrey D Messinger; Russell W Read; Clyde Guidry; Christine A Curcio; Imre Lengyel

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6535. doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Complement genes are differentially expressed in late age-related macular degeneration (AMD) and only in the neurosensory retina

Dwight Stambolian; Christine A Curcio; David Cho; James A. Kimble; Jeffrey D Messinger; Randy Zauhar; Mingyao Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Visualizing retinal pigment epithelium (RPE) melanosomes, lipofuscin, melanolipofuscin (M, L, ML) in human eyes of different ages using 3-dimensional serial block face scanning electron microscopy (3D SBFSEM)

Andreas Pollreisz; Jeffrey D Messinger; Kenneth R Sloan; Emily Benson; Grahame J Kidd; Ursula Schmidt-Erfurth; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi: https://doi.org/

ARVO Annual Meeting Abstract September 2016

Ex vivo spectral domain optical coherence tomography (ex-SDOCT) and high-resolution histology of drusenoid pigment epithelial detachment (D-PED) in age-related macular degeneration (AMD)

Jeffrey D Messinger; Chandra Bala; Kenneth R Sloan; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi: https://doi.org/

ARVO Annual Meeting Abstract June 2015

Choroidal neovascularization during and following vitelliform collapse: a clinical and histopathological study

Chandra Balaratnasingam; Christine A Curcio; Jeffrey D Messinger; Jonathan Naysan; Kunal K Dansingani; Lawrence A. Yannuzzi; K Bailey Freund

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3533. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2015

Prevalence, natural history, associations, and histological correlate of the Onion sign in neovascular age-related macular degeneration (nvAMD)

Jeffrey D Messinger; Claudine E Pang; Emma C. Zanzottera; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3782. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2015

Retinal pigment epithelium (RPE) transdifferentiation and death in age-related macular degeneration (AMD), seen in the Project MACULA grading system

Christine A Curcio; Emma C. Zanzottera; Jeffrey D Messinger; Thomas Ach; Theodore Smith; K Bailey Freund

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):893. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2015

Quantified autofluorescence maps of human retinal pigment epithelium in age-related macular degeneration (AMD)

Thomas Ach; Anna V Zarubina; Kristen M Hammack; Jeffrey D Messinger; Theodore Smith; Kenneth R Sloan; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2370. doi: https://doi.org/

ARVO Annual Meeting Abstract June 2015

Multinucleate RPE cells in normal human macula exhibit exquisite regional specificity

Austin Starnes; Carrie E Huisingh; Kristen M Hammack; Jeffrey D Messinger; Gerald McGwin; Kenneth R Sloan; Christine A Curcio; Thomas Ach

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2371. doi: https://doi.org/

Retinal Cell Biology May 2015

Lipofuscin Redistribution and Loss Accompanied by Cytoskeletal Stress in Retinal Pigment Epithelium of Eyes With Age-Related Macular Degeneration

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Thomas Ach; Elen Tolstik; Jeffrey D. Messinger; Anna V. Zarubina; Rainer Heintzmann; Christine A. Curcio
TAGS: actins, aging, cytoskeleton, lipofuscin, diagnostic imaging, eye, age-related macular degeneration, stress, granules, retinal pigment epithelium
Invest. Ophthalmol. Vis. Sci.. 2015; 56(5):3242-3252. doi: https://doi.org/10.1167/iovs.14-16274

Includes: Supplemental Content

Retina May 2015

The Project MACULA Retinal Pigment Epithelium Grading System for Histology and Optical Coherence Tomography in Age-Related Macular Degeneration

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Emma C. Zanzottera; Jeffrey D. Messinger; Thomas Ach; R. Theodore Smith; K. Bailey Freund; Christine A. Curcio
TAGS: phenotype, biological response modifiers, epithelium, atrophy, choroidal neovascularization, cicatrix, macula lutea, melanosomes, diagnostic imaging, eye
Invest. Ophthalmol. Vis. Sci.. 2015; 56(5):3253-3268. doi: https://doi.org/10.1167/iovs.15-16431

Includes: Supplemental Content

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Molecular Landscape of the Human Macula by High Resolution Imaging Mass Spectrometry

Migration patterns of intraretinal retinal pigment epithelium (RPE) in non-neovascular age-related macular degeneration (nnAMD)

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

Phenotypes of Retinal Pigment Epithelium (RPE) Autofluorescence (AF) and Morphology in Donor Eyes with Age-Related Macular Degeneration (AMD)

Photoreceptor (PR) degeneration, gliosis, and relation to supporting tissues in geographic atrophy (GA) of age-related macular degeneration (AMD)

Optimized human ocular tissue recovery and ex vivo multimodal imaging (MMI) for research in age-related macular degeneration (AMD)

Organelle subclasses in human retinal pigment epithelium (RPE) in younger and older eyes seen with 3-dimensional serial block face scanning electron microscopy (3D SBFSEM)

Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model

Histological stages of subretinal drusenoid deposits (SDD) in eyes with age-related macular degeneration (AMD)

A primary retinal pigment epithelial (RPE) cell culture model produces lipid- and hydroxyapatite-rich extracellular deposits characteristic of early stage age-related macular degeneration

Complement genes are differentially expressed in late age-related macular degeneration (AMD) and only in the neurosensory retina

Visualizing retinal pigment epithelium (RPE) melanosomes, lipofuscin, melanolipofuscin (M, L, ML) in human eyes of different ages using 3-dimensional serial block face scanning electron microscopy (3D SBFSEM)

Ex vivo spectral domain optical coherence tomography (ex-SDOCT) and high-resolution histology of drusenoid pigment epithelial detachment (D-PED) in age-related macular degeneration (AMD)

Choroidal neovascularization during and following vitelliform collapse: a clinical and histopathological study

Prevalence, natural history, associations, and histological correlate of the Onion sign in neovascular age-related macular degeneration (nvAMD)

Retinal pigment epithelium (RPE) transdifferentiation and death in age-related macular degeneration (AMD), seen in the Project MACULA grading system

Quantified autofluorescence maps of human retinal pigment epithelium in age-related macular degeneration (AMD)

Multinucleate RPE cells in normal human macula exhibit exquisite regional specificity

Lipofuscin Redistribution and Loss Accompanied by Cytoskeletal Stress in Retinal Pigment Epithelium of Eyes With Age-Related Macular Degeneration

The Project MACULA Retinal Pigment Epithelium Grading System for Histology and Optical Coherence Tomography in Age-Related Macular Degeneration

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