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Retina January 2025

Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

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Christine A. Curcio; Jeffrey D. Messinger; Andreas Berlin; Kenneth R. Sloan; D. Scott McLeod; Malia M. Edwards; Jacques Bijon; K. Bailey Freund
TAGS: age-related macular degeneration, age-related macular degeneration, nonexudative, atrophic condition of skin, atrophy, autofluorescence, drusen, fundus autofluorescence imaging, histology, pathology, clinical, photoreceptors
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):49. https://doi.org/10.1167/iovs.66.1.49

Includes: Multimedia, Supplemental Content

Retina November 2023

Imaging Histology Correlations of Intraretinal Fluid in Neovascular Age-Related Macular Degeneration

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Andreas Berlin; Jeffrey D. Messinger; Chandrakumar Balaratnasingam; Randev Mendis; Daniela Ferrara; K. Bailey Freund; Christine A. Curcio
TAGS: diagnostic imaging, exudative age-related macular degeneration, eye, histology, donors, cysts
Trans. Vis. Sci. Tech.. 2023; 12(11):13. https://doi.org/10.1167/tvst.12.11.13

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

How do outer retinal cells contribute to subretinal drusenoid deposit (SDD) in age-related macular degeneration (AMD)? an ultrastructural and immunohistochemistry investigation

Dongfeng Cao; Bibek Adhikari; Jeffrey D. Messinger; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2124.

ARVO Annual Meeting Abstract June 2023

Histology of cells suggestive of inflammation in treated neovascular age-related macular degeneration (AMD), a clinicopathologic correlation

Christine A. Curcio; Jeffrey D. Messinger; CHANDRAKUMAR Balaratnasingam; Randev Mendis; Daniela Ferrara; K. Bailey Freund; Andreas Berlin

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):2955.

ARVO Annual Meeting Abstract June 2023

Compromised Information Processing at the First Visual Synapse in a Mouse Model of Retinitis Pigmentosa RP59

Johan Pahlberg; Irina Ignatova; Ulisse Bocchero; Mai N Nguyen; Jeffrey D. Messinger; Steven Jay Fliesler; Steven J Pittler

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5412.

Retinal Cell Biology December 2022

Prolonged Lifetimes of Histologic Autofluorescence in Ectopic Retinal Pigment Epithelium in Age-Related Macular Degeneration

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Rowena Simon; Marius Jentsch; Parva Karimimousivandi; Dongfeng Cao; Jeffrey D. Messinger; Daniel Meller; Christine A. Curcio; Martin Hammer
TAGS: age-related macular degeneration, autofluorescence, retinal pigment epithelium, fluorescence, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2022; 63(13):5. https://doi.org/10.1167/iovs.63.13.5

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

What are the smallest clinically visible drusen in aging and age-related macular degeneration (AMD)? A histology and fluorescein angiography study

Charles Dwight Evers III; Ling Chen; Jeffrey D Messinger; Diogo Cabral; Rosa Dolz-Marco; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1021 – F0268.

ARVO Annual Meeting Abstract June 2022

Optical coherence tomography angiography of type 3 macular neovascularization, a clinicopathologic correlation

Andreas Berlin; Diogo Cabral; Ling Chen; Jeffrey D Messinger; Chandrakumar Balaratnasingam; Randev Mendis; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1018 – F0265.

ARVO Annual Meeting Abstract June 2022

Ultrastructural changes in the RPE and outer retina in a mouse knock-in model of RP59

Steven J Pittler; Sriganesh Ramachandra Rao; Steven J Fliesler; Jeffrey D Messinger; David M. Sherry

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2377 – A0061.

ARVO Annual Meeting Abstract June 2022

Human photoreceptor mitochondria (PR-Mit) are molecularly unique in healthy aged retina and outer retinal tubulation (ORT) of age-related macular degeneration (AMD)

Dongfeng Cao; Jeffrey D Messinger; Deepayan Kar; Thomas Ach; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2584 – F0467.

Retina August 2021

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

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Dongfeng Cao; Belinda Leong; Jeffrey D. Messinger; Deepayan Kar; Thomas Ach; Lawrence A. Yannuzzi; K. Bailey Freund; Christine A. Curcio
TAGS: age-related macular degeneration, atrophic condition of skin, atrophy, cell transdifferentiation, diagnostic imaging, donors, eye, immunohistochemistry, optical coherence tomography, phenotype
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):34. https://doi.org/10.1167/iovs.62.10.34

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2021

Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD)

Jeffrey D. Messinger; Ling Chen; Andreas Berlin; Deepayan Kar; Tommaso Bacci; Chandrakumar Balaratnasingham; Randev Mendes; Daniela Ferrara; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):654.

Retina January 2021

Biometrics, Impact, and Significance of Basal Linear Deposit and Subretinal Drusenoid Deposit in Age-Related Macular Degeneration

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Ling Chen; Jeffrey D. Messinger; Deepayan Kar; Jacque L. Duncan; Christine A. Curcio
TAGS: age-related macular degeneration, biometry, blinded, drusen, eye, lipids, visually impaired persons, volume
Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):33. https://doi.org/10.1167/iovs.62.1.33

Includes: Supplemental Content

Retina November 2020

Measuring the Contributions of Basal Laminar Deposit and Bruch's Membrane in Age-Related Macular Degeneration

PDF

Amol A. Sura; Ling Chen; Jeffrey D. Messinger; Thomas A. Swain; Gerald McGwin, Jr.; K. Bailey Freund; Christine A. Curcio

Invest. Ophthalmol. Vis. Sci.. 2020; 61(13):19. https://doi.org/10.1167/iovs.61.13.19

Includes: Supplemental Content

Retina September 2020

Fluorescence Lifetimes and Spectra of RPE and Sub-RPE Deposits in Histology of Control and AMD Eyes

PDF

Rowena Schultz; Kushmali C. L. K. Gamage; Jeffrey D. Messinger; Christine A. Curcio; Martin Hammer
TAGS: autofluorescence, eye, fluorescence, histology, donors
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):9. https://doi.org/10.1167/iovs.61.11.9

Articles July 2020

Recognizing Atrophy and Mixed-Type Neovascularization in Age-Related Macular Degeneration Via Clinicopathologic Correlation

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Ling Chen; Miaoling Li; Jeffrey D. Messinger; Daniela Ferrara; Christine A. Curcio; K. Bailey Freund
TAGS: age-related macular degeneration, atrophy, neovascularization, pathologic, drusen, eye, choroid, atrophic condition of skin, histology
Trans. Vis. Sci. Tech.. 2020; 9(8):8. https://doi.org/10.1167/tvst.9.8.8

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract August 2019

Molecular Landscape of the Human Macula by High Resolution Imaging Mass Spectrometry

Kevin Schey; David MG Anderson; Kate H. McKinney; Jeffrey D Messinger; N. Heath Patterson; Jeffrey M. Spraggins; Christine Curcio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(11):010.

ARVO Annual Meeting Abstract July 2019

Migration patterns of intraretinal retinal pigment epithelium (RPE) in non-neovascular age-related macular degeneration (nnAMD)

Belinda Leong; KENNETH R SLOAN; Jeffrey D Messinger; K Bailey Freund; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3453.

Retina June 2019

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

PDF

J. Alan Gambril; Kenneth R. Sloan; Thomas A. Swain; Carrie Huisingh; Anna V. Zarubina; Jeffrey D. Messinger; Thomas Ach; Christine A. Curcio
TAGS: age-related macular degeneration, autofluorescence, phenotype, retinal pigment epithelium, diagnostic imaging, eye
Invest. Ophthalmol. Vis. Sci.. 2019; 60(7):2481-2493. https://doi.org/10.1167/iovs.19-26949

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Phenotypes of Retinal Pigment Epithelium (RPE) Autofluorescence (AF) and Morphology in Donor Eyes with Age-Related Macular Degeneration (AMD)

John Alan Gambril; Kenneth R Sloan; Carrie E Huisingh; Jeffrey D Messinger; Thomas Ach; Christine A Curcio

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2437.

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Fundus Autofluorescence Variation in Geographic Atrophy of Age-Related Macular Degeneration: A Clinicopathologic Correlation

Imaging Histology Correlations of Intraretinal Fluid in Neovascular Age-Related Macular Degeneration

How do outer retinal cells contribute to subretinal drusenoid deposit (SDD) in age-related macular degeneration (AMD)? an ultrastructural and immunohistochemistry investigation

Histology of cells suggestive of inflammation in treated neovascular age-related macular degeneration (AMD), a clinicopathologic correlation

Compromised Information Processing at the First Visual Synapse in a Mouse Model of Retinitis Pigmentosa RP59

Prolonged Lifetimes of Histologic Autofluorescence in Ectopic Retinal Pigment Epithelium in Age-Related Macular Degeneration

What are the smallest clinically visible drusen in aging and age-related macular degeneration (AMD)? A histology and fluorescein angiography study

Optical coherence tomography angiography of type 3 macular neovascularization, a clinicopathologic correlation

Ultrastructural changes in the RPE and outer retina in a mouse knock-in model of RP59

Human photoreceptor mitochondria (PR-Mit) are molecularly unique in healthy aged retina and outer retinal tubulation (ORT) of age-related macular degeneration (AMD)

Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

Multiscale clinicopathologic correlation of canonical and non-canonical intraretinal neovascularization in age-related macular degeneration (AMD)

Biometrics, Impact, and Significance of Basal Linear Deposit and Subretinal Drusenoid Deposit in Age-Related Macular Degeneration

Measuring the Contributions of Basal Laminar Deposit and Bruch's Membrane in Age-Related Macular Degeneration

Fluorescence Lifetimes and Spectra of RPE and Sub-RPE Deposits in Histology of Control and AMD Eyes

Recognizing Atrophy and Mixed-Type Neovascularization in Age-Related Macular Degeneration Via Clinicopathologic Correlation

Molecular Landscape of the Human Macula by High Resolution Imaging Mass Spectrometry

Migration patterns of intraretinal retinal pigment epithelium (RPE) in non-neovascular age-related macular degeneration (nnAMD)

Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

Phenotypes of Retinal Pigment Epithelium (RPE) Autofluorescence (AF) and Morphology in Donor Eyes with Age-Related Macular Degeneration (AMD)

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