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ARVO Annual Meeting Abstract June 2024

SORTILIN INHIBITION PROTECTS THE RETINA BY REDUCING INFLAMMATION AND LYSOSOMAL ACTIVITY

Jena J Steinle; Li Liu; youde Jiang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3839.

ARVO Annual Meeting Abstract June 2022

TNFAIP3 may be key to TLR4-activation of the inflammasome in the retinal vasculature

Li Liu; Youde Jiang; Jena Jean Steinle

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):276 – F0321.

Retinal Cell Biology January 2022

PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature

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Li Liu; Youde Jiang; Jena J. Steinle
TAGS: inflammasomes, nlr family, pyrin domain-containing 3 protein, proteins, mice, dna, complementary, retinal vasculature
Invest. Ophthalmol. Vis. Sci.. 2022; 63(1):14. https://doi.org/10.1167/iovs.63.1.14

Retinal Cell Biology September 2020

Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature

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Youde Jiang; Jena J. Steinle
TAGS: ampk, hmgb1 protein, phosphorylation, retina, retinal vasculature, glucose
Invest. Ophthalmol. Vis. Sci.. 2020; 61(11):33. https://doi.org/10.1167/iovs.61.11.33

ARVO Annual Meeting Abstract June 2020

Diabetic Cornea: Effects of PM 2.5 and glycyrrhizin treatment.

Mallika Somayajulu; Sharon Ann McClellan; Sandamali Ekanayaka; Ahalya Pitchaikannu; Jena J Steinle; Linda D Hazlett

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4081.

Immunology and Microbiology February 2020

Role of Insulin-Like Growth Factor Binding Protein-3 in the Pathogenesis of Herpes Stromal Keratitis

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Pushpa Rao; Pratima K. Suvas; Andrew D. Jerome; Jena J. Steinle; Susmit Suvas
TAGS: cornea, human herpesvirus 1, infections, insulin-like growth factor binding protein 3, mice, proteins, insulin-like growth factor i, pathogenesis, stromal keratitis, somatomedins
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):46. https://doi.org/10.1167/iovs.61.2.46

ARVO Annual Meeting Abstract July 2019

Role of Insulin-like growth factor binding protein-3 (IGFBP-3) in pathogenesis of herpes stromal keratitis (HSK)

Susmit Suvas; Pushpa Rao; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4627.

ARVO Annual Meeting Abstract July 2018

Retinal ischemia reperfusion injury model: a contrast in pathogenic responses between C57BL/6J versus BALB/cJ mice

Haoshen Shi; Jena J Steinle; Elizabeth A Berger

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1209.

ARVO Annual Meeting Abstract July 2018

miRNA15 Regulates Insulin Signal Transduction in the Retinal Vasculature

Youde Jiang; Li Liu; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3540.

ARVO Annual Meeting Abstract July 2018

Loss of TLR4 in Mouse Müller cells inhibits both MyD88-dependent and –independent signaling

Li Liu; Youde Jiang; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3541.

ARVO Annual Meeting Abstract July 2018

miR15a Regulates NLRP3 Inflammasome Actions in the Retinal Vasculature

Elizabeth Curtiss; Li Liu; Youde Jiang; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3547.

ARVO Annual Meeting Abstract June 2017

miR-15a/16 inhibits TGF-beta3 and SMAD2/3 signaling and maintains retinal endothelial barrier

Eun-Ah Ye; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2515.

ARVO Annual Meeting Abstract June 2017

TLR4 inhibits insulin signaling, leading to increased apoptosis in mouse retina

Youde Jiang; Li Liu; Elizabeth Curtiss; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4045.

ARVO Annual Meeting Abstract June 2017

TLR4 plays an important role in regulating ZO-1 and occludin levels, as well as retinal damage following ischemia-reperfusion injury

Li Liu; Youde Jiang; Elizabeth Curtiss; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5203.

ARVO Annual Meeting Abstract June 2017

Site specific phosphorylation of NF-κB p65 in human retinal cells exposed to pro- versus anti-inflammatory cytokines under high glucose conditions

Haoshen Shi; Jena J Steinle; Elizabeth A Berger

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5212.

Retinal Cell Biology January 2017

Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature

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Youde Jiang; Li Liu; Jena J. Steinle
TAGS: endothelial cells, mice, proteins, retinal vasculature, vascular endothelial growth factor a, permeability, glucose, rna, small interfering, western blotting
Invest. Ophthalmol. Vis. Sci.. 2017; 58(1):185-189. https://doi.org/10.1167/iovs.16-20412

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

miR15a/16 mediates protective effects of beta-adrenergic signaling to reduce leukostasis in diabetic retinopathy

Li Liu; Eun-Ah Ye; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3211.

ARVO Annual Meeting Abstract September 2016

Epac1 is required for Beta-Adrenergic Receptor Regulation of VEGF in Retinal Endothelial Cells Grown in High Glucose

Youde Jiang; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3212.

ARVO Annual Meeting Abstract September 2016

Human retinal microvascular endothelial cells differentially respond to hyperglycemic conditions when exposed to Th1- versus Th2-dominant cytokines

Haoshen Shi; Jena J Steinle; Elizabeth A Berger

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5428.

ARVO Annual Meeting Abstract September 2016

miR-146a protects primary human retinal microvascular endothelial cells from hyperglycemia-induced apoptosis by attenuating inflammatory pathways mediated by TLR4/NF-κB and TNF alpha.

Eun-Ah Ye; Jena J Steinle

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5432.

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SORTILIN INHIBITION PROTECTS THE RETINA BY REDUCING INFLAMMATION AND LYSOSOMAL ACTIVITY

TNFAIP3 may be key to TLR4-activation of the inflammasome in the retinal vasculature

PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature

Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature

Diabetic Cornea: Effects of PM 2.5 and glycyrrhizin treatment.

Role of Insulin-Like Growth Factor Binding Protein-3 in the Pathogenesis of Herpes Stromal Keratitis

Role of Insulin-like growth factor binding protein-3 (IGFBP-3) in pathogenesis of herpes stromal keratitis (HSK)

Retinal ischemia reperfusion injury model: a contrast in pathogenic responses between C57BL/6J versus BALB/cJ mice

miRNA15 Regulates Insulin Signal Transduction in the Retinal Vasculature

Loss of TLR4 in Mouse Müller cells inhibits both MyD88-dependent and –independent signaling

miR15a Regulates NLRP3 Inflammasome Actions in the Retinal Vasculature

miR-15a/16 inhibits TGF-beta3 and SMAD2/3 signaling and maintains retinal endothelial barrier

TLR4 inhibits insulin signaling, leading to increased apoptosis in mouse retina

TLR4 plays an important role in regulating ZO-1 and occludin levels, as well as retinal damage following ischemia-reperfusion injury

Site specific phosphorylation of NF-κB p65 in human retinal cells exposed to pro- versus anti-inflammatory cytokines under high glucose conditions

Compound 49b Regulates ZO-1 and Occludin Levels in Human Retinal Endothelial Cells and in Mouse Retinal Vasculature

miR15a/16 mediates protective effects of beta-adrenergic signaling to reduce leukostasis in diabetic retinopathy

Epac1 is required for Beta-Adrenergic Receptor Regulation of VEGF in Retinal Endothelial Cells Grown in High Glucose

Human retinal microvascular endothelial cells differentially respond to hyperglycemic conditions when exposed to Th1- versus Th2-dominant cytokines

miR-146a protects primary human retinal microvascular endothelial cells from hyperglycemia-induced apoptosis by attenuating inflammatory pathways mediated by TLR4/NF-κB and TNF alpha.

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