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Genetics July 2020

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

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Milica A. Margeta; Sophia M. Letcher; Robert P. Igo, Jr.; Jessica N. Cooke Bailey; Louis R. Pasquale; Jonathan L. Haines; Oleg Butovsky; Janey L. Wiggs; for the NEIGHBORHOOD consortium
TAGS: apolipoprotein e, glaucoma, open-angle glaucoma, trem2 gene, alleles
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):3. doi: https://doi.org/10.1167/iovs.61.8.3

ARVO Annual Meeting Abstract June 2020

Analysis of ATXN2 trinucleotide repeats in primary open angle glaucoma patients

Shi Song Rong; Robert Igo; Jessica Cooke Bailey; Jonathan L Haines; Louis Pasquale; Janey Wiggs

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1247. doi:

ARVO Annual Meeting Abstract June 2020

Glaucoma Examination in the Amish of Holmes County, Ohio

Jonathan Mikal Skarie; Tyler G Kinzy; Jane Sewell; Yeunjoo E Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Sherri Hochstetler; Louis R Pasquale; Janey Wiggs; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1252. doi:

ARVO Annual Meeting Abstract June 2020

Statistical driver genes and the missing heritability of age-related macular degeneration

Andrea R Waksmunski; Michelle Grunin; Tyler G Kinzy; Robert Igo; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1895. doi:

ARVO Annual Meeting Abstract June 2020

Phenome-wide association analysis on risk variants for age-related macular degeneration reveals shared genetic influences with a wide range of disorders: the Million Veteran Program

Robert Igo; Tyler G Kinzy; Christopher W. Halladay; Dana C. Crawford; Paul B Greenberg; Jack M. Sullivan; Steven J. Fliesler; Wen-Chih Wu; Helene Choquet; Karina Patasova; Eric Jorgenson; Pirro G Hysi; Andrew J Lotery; Jessica Cooke Bailey; Neal S. Peachey; Sudha K Iyengar

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3518. doi:

ARVO Annual Meeting Abstract June 2020

Computable phenotyping for primary open-angle glaucoma using electronic health records in the Million Veteran Program

Jessica Cooke Bailey; Cari L. Nealon; Christopher W. Halladay; Piana Krymskaya; Scott A. Anthony; David P. Roncone; Rachael Canania; Tyler G Kinzy; Robert Igo; Paul B Greenberg; Dana C. Crawford; Sudha K Iyengar; Jack M Sullivan; Wen-Chih Wu; Neal S. Peachey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4555. doi:

Genetics September 2019

Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

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Andrea R. Waksmunski; Michelle Grunin; Tyler G. Kinzy; Robert P. Igo, Jr; Jonathan L. Haines; Jessica N. Cooke Bailey; for the International Age-Related Macular Degeneration Genomics Consortium
TAGS: age-related macular degeneration, candidate disease gene, genes, genome, genome-wide association study, ophthalmology, universities, schools, medical, proteins, genetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4041-4051. doi: https://doi.org/10.1167/iovs.19-27827

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Glaucoma Examination in the Amish of Holmes County, Ohio

Jonathan Mikal Skarie; Tyler Kinzy; Jane Sewell; Yeunjoo E. Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Erika Trapl; Farren BS Briggs; Louis R Pasquale; Janey L Wiggs; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1602. doi:

ARVO Annual Meeting Abstract July 2019

Association of APOE with POAG suggests a protective effect for APOE4

Sophia M Letcher; Milica Margeta; Robert P. Igo; Jessica Cooke Bailey; Jonathan L Haines; Oleg Butovsky; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1627. doi:

ARVO Annual Meeting Abstract July 2019

Pathway analysis identifies PLCG2 as a candidate gene for age-related macular degeneration

Andrea R Waksmunski; Michelle Grunin; Tyler Kinzy; Robert P. Igo; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2959. doi:

ARVO Annual Meeting Abstract July 2019

Genetic analysis of self-reported glaucoma from the Health and Retirement Study

Jessica Cooke Bailey; Tyler Kinzy; Nicholas Schiltz

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5419. doi:

Clinical and Epidemiologic Research December 2018

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

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Cecilia Chao; Lakshmi Akileswaran; Jessica N. Cooke Bailey; Mark Willcox; Russell Van Gelder; Carol Lakkis; Fiona Stapleton; Kathryn Richdale
TAGS: contact lenses, cornea, cytokine, environmental factors, genotype, microbiome, whole exome sequencing, interleukin-6
Invest. Ophthalmol. Vis. Sci.. 2018; 59(15):5752-5761. doi: https://doi.org/10.1167/iovs.18-24845

Includes: Supplemental Content

Retina October 2018

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

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Sabrina L. Mitchell; Karan Uppal; Samantha M. Williamson; Ken Liu; L. Goodwin Burgess; ViLinh Tran; Allison C. Umfress; Kelli L. Jarrell; Jessica N. Cooke Bailey; Anita Agarwal; Margaret Pericak-Vance; Jonathan L. Haines; William K. Scott; Dean P. Jones; Milam A. Brantley, Jr
TAGS: carnitine, exudative age-related macular degeneration, metabolites, metabolomics, plasma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4978-4985. doi: https://doi.org/10.1167/iovs.18-25137

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

GENOMIC LOCUS MODULATING CORNEAL THICKNESS IN THE MOUSE IDENTIFIES POU6F2 , A POTENTIAL RISK OF DEVELOPING GLAUCOMA

Eldon E Geisert; Rebecca King; Felix Struebing; Ying Li; Jiaxing Wang; Jessica Cook Bailey; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1181. doi:

ARVO Annual Meeting Abstract July 2018

Genome-wide association study of intraocular pressure identifies 83 novel loci

Anthony P Khawaja; Jessica Cooke Bailey; Mark James Simcoe; Robert P Igo; Louis R. Pasquale; Paul J Foster; Janey L Wiggs; Christopher J Hammond; Pirro G Hysi

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1178. doi:

ARVO Annual Meeting Abstract July 2018

Identifying genes that underlie Primary Open-Angle Glaucoma using genetically determined gene expression

Jibril Hirbo; Jessica Cooke Bailey; Patrick Evans; Eric R Gamazon; Ran Tao; Karen M Joos; Milam A Brantley; Janey L Wiggs; Nancy J Cox

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1180. doi:

ARVO Annual Meeting Abstract July 2018

Genetic, metagenomic, host response, and environmental factors influences on corneal infiltrative events in soft contact lens wearers: the MERGE pilot study

Kathryn Richdale; Cecilia Chao; Lakshmi Akileswaran; Russell Van Gelder; Jessica Cooke Bailey; Jonathan L Haines; Fiona Stapleton; Carol Lakkis; Mark D P Willcox

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1743. doi:

ARVO Annual Meeting Abstract July 2018

Glaucoma Examination in the Amish of Holmes County, Ohio

Jessica Cooke Bailey; Yeunjoo E Song; Jonathan Mikal Skarie; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Louis R. Pasquale; Janey L Wiggs; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1818. doi:

ARVO Annual Meeting Abstract July 2018

Identifying Novel Genetic Loci associated with Primary Open-Angle Glaucoma

Sangbea Kim; Zhihua Qi; Yuhong Chen; Yumei Li; Benjamin Jay Jay Frankfort; Xing-Huai Sun; Jessica Cooke Bailey; Janey L Wiggs; Yongtao Guan; Rui Chen

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5142. doi:

Genetics May 2018

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

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Bao Jian Fan; Xueli Chen; Nisha Sondhi; P. Ferdinamarie Sharmila; Nagasamy Soumittra; Sarangapani Sripriya; Srinivasan Sacikala; Rashima Asokan; David S. Friedman; Louis R. Pasquale; X. Raymond Gao; Lingam Vijaya; Jessica Cooke Bailey; Veronique Vitart; Stuart MacGregor; Christopher J. Hammond; Chiea Chuen Khor; Jonathan L. Haines; Ronnie George; Janey L. Wiggs; for the Mexican American Glaucoma Genetic Study; International Glaucoma Genetics Consortium; and NEIGHBORHOOD Consortium
TAGS: cohort studies, cornea, family, genetic pedigree, genome-wide association study, single nucleotide polymorphism
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2495-2502. doi: https://doi.org/10.1167/iovs.17-23536

Includes: Supplemental Content

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Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

Analysis of ATXN2 trinucleotide repeats in primary open angle glaucoma patients

Glaucoma Examination in the Amish of Holmes County, Ohio

Statistical driver genes and the missing heritability of age-related macular degeneration

Phenome-wide association analysis on risk variants for age-related macular degeneration reveals shared genetic influences with a wide range of disorders: the Million Veteran Program

Computable phenotyping for primary open-angle glaucoma using electronic health records in the Million Veteran Program

Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

Glaucoma Examination in the Amish of Holmes County, Ohio

Association of APOE with POAG suggests a protective effect for APOE4

Pathway analysis identifies PLCG2 as a candidate gene for age-related macular degeneration

Genetic analysis of self-reported glaucoma from the Health and Retirement Study

Potential Role of Ocular Microbiome, Host Genotype, Tear Cytokines, and Environmental Factors in Corneal Infiltrative Events in Contact Lens Wearers

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

GENOMIC LOCUS MODULATING CORNEAL THICKNESS IN THE MOUSE IDENTIFIES POU6F2 , A POTENTIAL RISK OF DEVELOPING GLAUCOMA

Genome-wide association study of intraocular pressure identifies 83 novel loci

Identifying genes that underlie Primary Open-Angle Glaucoma using genetically determined gene expression

Genetic, metagenomic, host response, and environmental factors influences on corneal infiltrative events in soft contact lens wearers: the MERGE pilot study

Glaucoma Examination in the Amish of Holmes County, Ohio

Identifying Novel Genetic Loci associated with Primary Open-Angle Glaucoma

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

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