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Biochemistry and Molecular Biology June 2025

Machine Learning Identifies Key Gene Markers Related to Fetal Retina Development at Single-Cell Transcription Level

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Jiyu Zhang; Tong Du; Yiqing Jin; Yusheng Bao; Qinglan Ma; Yu-Dong Cai; Jian Zhang
TAGS: fetus, genes, retina, machine learning, rod photoreceptors, retinal cone, retinal diseases, classification algorithms
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):60. https://doi.org/10.1167/iovs.66.6.60

Includes: Supplemental Content

Refractive Intervention May 2025

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

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Yue Xu; Xing-Xuan Dong; Yun Wang; Xin-Yu Zhuang; Ying-Jie Chen; Xiao-Feng Zhang; Chen-Wei Pan
TAGS: cytokine, mendelian randomization analysis, refractive errors, ciliary motility disorders
Trans. Vis. Sci. Tech.. 2025; 14(5):1. https://doi.org/10.1167/tvst.14.5.1

Includes: Supplemental Content

Cornea April 2025

Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair

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An Wang; Zongyuan Li; Yilin Jiang; Mingxiong Chen; Hanrui Yu; Zhao Li; Shengshu Sun; Ge Bai; Qun Wang; Yifei Huang; Liqiang Wang
TAGS: alkalies, burns, cornea, corneal injuries, limbal stem cells, lymphatic vessels, prospero-related homeobox 1 protein, recovery of function, epithelium, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):81. https://doi.org/10.1167/iovs.66.4.81

Includes: Supplemental Content

Retina March 2025

Photoreceptor Outer Segment Reflectivity With Ultrahigh-Resolution Visible-Light Optical Coherence Tomography in Systemic Hydroxychloroquine Use

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Anupam K. Garg; Jingyu Wang; Bailee Alonzo; Ji Yi; Amir H. Kashani
TAGS: hydroxychloroquine, optical coherence tomography, photoreceptors, vaccine information sheets, visible light, diagnostic imaging, toxic effect
Trans. Vis. Sci. Tech.. 2025; 14(3):2. https://doi.org/10.1167/tvst.14.3.2

Includes: Supplemental Content

Glaucoma February 2025

Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

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Jingyu Wang; Natalie Sadlak; Marissa G. Fiorello; Manishi Desai; Ji Yi
TAGS: glaucoma, optical coherence tomography, oximetry, oxygen saturation measurement, pilot projects, somalia, visible light, eye, antistreptolysin o, arteriosclerosis obliterans
Trans. Vis. Sci. Tech.. 2025; 14(2):12. https://doi.org/10.1167/tvst.14.2.12

Includes: Supplemental Content

Retinal Cell Biology January 2025

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

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Qi Liu; Ling-Xiao Xia; Wan-Zhao Yi; Ya-Ni Wu; Shuo-Shuo Gu; Jian-Ying Chen; Ting-Ting Liu; Ying-Hui Lu; Yu-Hong Cui; Jing Meng; Hong-Wei Pan
TAGS: cyclin d1, endothelial cells, proto-oncogene proteins c-akt, retinal neovascularization, cell cycle, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):66. https://doi.org/10.1167/iovs.66.1.66

Includes: Supplemental Content

Retina January 2025

ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype

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Yingwei Wang; Pangfeng Wang; Zhen Yi; Jiamin Ouyang; Yi Jiang; Shiqiang Li; Xiaoyun Jia; Xueshan Xiao; James Fielding Hejtmancik; Wenmin Sun; Qingjiong Zhang
TAGS: abca4 gene, introns, phenotype
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):65. https://doi.org/10.1167/iovs.66.1.65

Includes: Supplemental Content

Retinal Cell Biology January 2025

DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells

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Xueying Wang; Xi Wang; Zhenzhen Zhao; Qian Wang; Xiaoman Zhu; Qingjian Ou; Jing-Ying Xu; Lixia Lu; Furong Gao; Juan Wang; Yanlong Bi; Guo-Tong Xu; Caixia Jin; Haibin Tian
TAGS: ferroptosis, prkdc gene, retinal pigment cell, catalytic domain, dna damage, phosphorylation
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):50. https://doi.org/10.1167/iovs.66.1.50

Includes: Supplemental Content

Retinal Cell Biology January 2025

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

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Ao-Wang Qiu; Ning-Yu Wang; Wen-Jie Yin; Zhao-Qi Zhu; Qing-Huai Liu; Wei-Wei Zhang
TAGS: cardiac support procedures, exosomes, interleukin-17, mast-cell sarcoma, millennium cohort study, minimally conscious state, diabetic retinopathy, interleukins, mice
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):1. https://doi.org/10.1167/iovs.66.1.1

Cornea November 2024

Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost

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XiaoBo Zheng; Chong Wang; YiWen Fan; YuXin Hong; Han Bao; ErChi Zhang; Yi Jin; Peng Yang; LingQiao Li; JunJie Wang; ShiHao Chen; Ahmed Elsheikh; FangJun Bao
TAGS: cornea, oryctolagus cuniculus, travoprost, cardiac ct, multiple wake test, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):35. https://doi.org/10.1167/iovs.65.13.35

Clinical and Epidemiologic Research November 2024

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

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Yanze Yu; Hao Chen; Zhanying Wang; Yuhao Ye; Zhe Zhang; Yongle Bao; Yingnan Jia; Xingtao Zhou; Jing Zhao
TAGS: biochemistry, chronic disease, diabetes mellitus, type 2, myopia, prospective studies, refractive errors
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):26. https://doi.org/10.1167/iovs.65.13.26

Includes: Supplemental Content

Vision Sciences Society Annual Meeting Abstract September 2024

Faster categorization of the majority-race faces in a multiracial society

Charles C.-F. Or; Bo Zhen Lu; Nadia Mazlan; Yi Jie Toh; Alan L.F. Lee

Journal of Vision. 2024; 24(10):439. https://doi.org/10.1167/jov.24.10.439

Genetics August 2024

The Systemic Genotype-Phenotype Characterization of PAX6 -Related Eye Disease in 164 Chinese Families

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Yi Jiang; Zhen Yi; Yuxi Zheng; Jiamin Ouyang; Dongwei Guo; Shiqiang Li; Xueshan Xiao; Panfeng Wang; Wenmin Sun; Qingjiong Zhang
TAGS: pax6 transcription factor, phenotype, family, eye, eye diseases, cohort studies, genotype, chinese (other dialects), chinese people
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):46. https://doi.org/10.1167/iovs.65.10.46

Includes: Supplemental Content

Retina August 2024

Optical Assessment of Photoreceptor Function Over the Macula

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Shuibin Ni; Shanjida Khan; Alfonso Jiménez-Villar; Mark E. Pennesi; David Huang; Yifan Jian; Siyu Chen
TAGS: diagnostic imaging, macula lutea, optics, photoreceptors, retinal cone
Trans. Vis. Sci. Tech.. 2024; 13(8):41. https://doi.org/10.1167/tvst.13.8.41

Includes: Supplemental Content

ARVO Imaging in the Eye Conference Abstract July 2024

U-Net-derived automated segmentation of neovascular tufts (Popcorn neovascularization) in retinopathy of prematurity using ultra-widefield optical coherence tomography scans

Spencer Burt; Mani Woodward; Shuibin Ni; Aaron Coyner; Benjamin K Young; Yifan Jian; Susan Ostmo; Yali Jia; David Huang; J. Peter Campbell

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PB0012.

ARVO Imaging in the Eye Conference Abstract July 2024

Panretinal high-resolution OCT angiography for rodent imaging

Guangru Ben Liang; Tristan T. Hormel; Shuibin Ni; Yifan Jian; Yali Jia

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PP0013.

ARVO Imaging in the Eye Conference Abstract July 2024

Ultrahigh-speed swept-source optical coherence tomography for macular optoretinography

Shuibin Ni; Shanjida Khan; Alfonso Jiménez-Villar; Mark E. Pennesi; Steven T. Bailey; David Huang; Yifan Jian; Siyu Chen

Invest. Ophthalmol. Vis. Sci.. 2024; 65(9):PP0023.

ARVO Annual Meeting Abstract June 2024

Macular Oxygen Saturation in Normal, Non-proliferative, and Proliferative Diabetic Retinopathy Subjects Using Visible Light Optical Coherence Tomography

Jingyu Wang; Andrew Baker; Marissa Fiorello; Steven Ness; Ji Yi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3355.

ARVO Annual Meeting Abstract June 2024

A Novel Murine Model of Neurotrophic Keratopathy

Sheyda Najafi; Zhirong Lin; Asmaa Zidan; Amirreza Naderi; Gabriel Corfas; Jia Yin

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6500.

ARVO Annual Meeting Abstract June 2024

Cultivated Autologous Limbal Epithelial Cell (CALEC) Transplantation for Limbal Stem Cell Deficiency

Ula V Jurkunas; Aaron Kaufman; Jia Yin; Allison Ayala; Maureen Maguire; Lassana Samarakoon; Lynette Johns; Mohit Parekh; Sanming Li; Helene Negre; Kit Shaw; Diego Hernandez; Heather Daley; Reza Dana; Myriam Armant; Jerome Ritz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2801.

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Machine Learning Identifies Key Gene Markers Related to Fetal Retina Development at Single-Cell Transcription Level

Association Between Inflammatory Cytokines and Refractive Errors: A Bidirectional Mendelian Randomization Study

Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair

Photoreceptor Outer Segment Reflectivity With Ultrahigh-Resolution Visible-Light Optical Coherence Tomography in Systemic Hydroxychloroquine Use

Macular Oxygen Saturation in Glaucoma Using Retinal Oximetry of Visible Light Optical Coherence Tomography: A Pilot Study

Inhibition of Retinal Neovascularization by BEZ235: Targeting the Akt/4EBP1/Cyclin D1 Pathway in Endothelial Cells

ABCA4 Deep Intronic Variants Contributed to Nearly Half of Unsolved Stargardt Cases With a Milder Phenotype

DNA-Dependent Protein Kinase Catalytic Subunit Prevents Ferroptosis in Retinal Pigment Epithelial Cells

Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy

Restoration of Corneal Stiffness in Rabbits Following Withdrawal of Travoprost

Exploring the Relationship Between Refractive Errors and Common Chronic Diseases Via Blood Biochemistry Tests: A Large Prospective Cohort Study

Faster categorization of the majority-race faces in a multiracial society

The Systemic Genotype-Phenotype Characterization of PAX6 -Related Eye Disease in 164 Chinese Families

Optical Assessment of Photoreceptor Function Over the Macula

U-Net-derived automated segmentation of neovascular tufts (Popcorn neovascularization) in retinopathy of prematurity using ultra-widefield optical coherence tomography scans

Panretinal high-resolution OCT angiography for rodent imaging

Ultrahigh-speed swept-source optical coherence tomography for macular optoretinography

Macular Oxygen Saturation in Normal, Non-proliferative, and Proliferative Diabetic Retinopathy Subjects Using Visible Light Optical Coherence Tomography

A Novel Murine Model of Neurotrophic Keratopathy

Cultivated Autologous Limbal Epithelial Cell (CALEC) Transplantation for Limbal Stem Cell Deficiency

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