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ARVO Annual Meeting Abstract June 2017

Co-expression of human L- or M-opsin restores M-Cone Function in the Opn1mw Knock-out mouse, a model for blue cone monochromacy (BCM)

Wentao Deng; Ji-Jing Pang; Jie Li; Ping Zhu; Wolfgang Baehr; W. Clay Smith; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4477.

ARVO Annual Meeting Abstract June 2017

Restoration of M-cone function in an S-cone only mouse model of human blue cone monochromacy by AAV-mediated expression of human L- or M-opsin

Ji-Jing Pang; Wentao Deng; Yuxin Zhang; Jie Li; Ping Zhu; Wolfgang Baehr; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4478.

ARVO Annual Meeting Abstract September 2016

Gene therapy in the Opn1mw Knock-out mouse, a model for blue cone monochromacy, leads to long-term M-cone restoration

Ji-Jing Pang; Yuxin Zhang; Ping Zhu; Wen-Tao Deng; Jie Li; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1166.

ARVO Annual Meeting Abstract September 2016

Long term restoration of cone function following AAV-mediated gene therapy in CNGA3 -/- Nrl -/- Mice

Yuxin Zhang; Wei Du; Ping Zhu; Jie Li; Wen-Tao Deng; Chen Zhao; William Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1175.

ARVO Annual Meeting Abstract June 2015

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Opn1mw KO Mice

Ji-Jing Pang; Wei Du; Ping Zhu; Yuxin Zhang; Jinfeng Sun; Wolfgang Baehr; Sanford L Boye; William W Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1092.

ARVO Annual Meeting Abstract April 2014

AAV-mediated Gene Therapy Restores Cone Function in the Cnga3/Nrl Double Knockout Mouse following intravitreous injection

Ji-Jing Pang; Ye Tao; Wei Du; Sanford L Boye; Jie Li; Wen-tao Deng; William W Hauswirth; Shannon Boye

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3317.

ARVO Annual Meeting Abstract April 2014

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Thrb Knockout Mouse

Wei Du; Wen-tao Deng; Sanford L Boye; Jie Li; Wei Li; William W Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3318.

Retina March 2014

AAV-Mediated Lysophosphatidylcholine Acyltransferase 1 ( Lpcat1 ) Gene Replacement Therapy Rescues Retinal Degeneration in rd11 Mice

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Xufeng Dai; Juanjuan Han; Yan Qi; Hua Zhang; Lue Xiang; Jineng Lv; Jie Li; Wen-Tao Deng; Bo Chang; William W. Hauswirth; Ji-jing Pang
TAGS: gene therapy, mice, retinal degeneration, eye, 1-acylglycerophosphocholine o-acyltransferase, did not receive therapy or drug, retinal cone, retina
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1724-1734. https://doi.org/10.1167/iovs.13-13654

ARVO Annual Meeting Abstract June 2013

AAV-mediated Lpcat1 gene replacement therapy rescues retinal degeneration in rd11 mice

Xufeng Dai; Juanjuan Han; Zi-Bing Jin; Yan Qi; Jie Li; Wen-Tao Deng; Bo Chang; William Hauswirth; Ji-Jing Pang

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2715.

ARVO Annual Meeting Abstract June 2013

AAV-mediated gene therapy restores cone function in the Cnga3/Nrl double knockout mouse

Ji-Jing Pang; Ye Tao; Sanford Boye; Jie Li; Wen-Tao Deng; Xi-Qin Ding; Stylianos Michalakis; Martin Biel; Shannon Boye; William Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2723.

Retina March 2013

Visual Signal Pathway Reorganization in the Cacna1f Mutant Rat Model

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Ye Tao; Tao Chen; Bei Liu; Jun Hui Xue; Lei Zhang; Feng Xia; Ji-jing Pang; Zuo Ming Zhang
TAGS: mutation, photoreceptors, retina, signal pathway, night blindness, congenital stationary, rats
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):1988-1997. https://doi.org/10.1167/iovs.12-10706

ARVO Annual Meeting Abstract March 2012

Cone Targeted AAV-mediated Gene Therapy Restores Cone Function in the Cngb3 Knockout Mouse, a Model of Human Achromatopsia 1

Wei Shi; Song Mao; Wentao Deng; Jie Li; Xuan Liu; Sanford L. Boye; Guo-jie Ye; Willaim W. Hauswirth; Ji-jing Pang

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1903.

ARVO Annual Meeting Abstract March 2012

AAV-mediated Cone Targeted Gene Therapy To Cpfl5 Mouse, A Model of Human Achromatopsia 2 with Mutations in Cnga3

Ji-Jing Pang; Song Mao; Wei Shi; Wentao Deng; Shannon E. Boye; Jie Li; Xuan Liu; Sanford L. Boye; Bo Chang; William W. Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1915.

ARVO Annual Meeting Abstract March 2012

Differential Proteomics and Functional Research Following Gene Therapy in a Mouse Model of RPE65 Leber's Congenital Amaurosis

Wensheng Li, Sr.; Radouil T. Tzekov; Qinxiang Zheng; Xufeng Dai; Ji-Jing Pang; Jia Qu

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1929.

ARVO Annual Meeting Abstract April 2011

AAV-mediated Gene Therapy Restores Cone Function in the Cngb3 Knockout Mouse, a Model of Human Achromatopsia 1

Ji-Jing Pang; Wen-Tao Deng; Song Mao; Jie Li; Xuan Liu; Guo-jie Ye; William W. Hauswirth

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4376.

Biochemistry and Molecular Biology January 2011

Gene Therapy Rescues Cone Structure and Function in the 3-Month-Old rd12 Mouse: A Model for Midcourse RPE65 Leber Congenital Amaurosis

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Xia Li; Wensheng Li; Xufeng Dai; Fansheng Kong; Qinxiang Zheng; Xiangtian Zhou; Fan Lü; Bo Chang; Bärbel Rohrer; William. W. Hauswirth; Jia Qu; Ji-jing Pang
TAGS: gene therapy, leber's amaurosis, mice, retinal cone, retina, opsin, eye, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2011; 52(1):7-15. https://doi.org/10.1167/iovs.10-6138

Retinal Cell Biology May 2010

Paracrine Modulation of CXCR4 by IGF-1 and VEGF: Implications for Choroidal Neovascularization

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Nilanjana Sengupta; Aqeela Afzal; Sergio Caballero; Kyung-Hee Chang; Lynn C. Shaw; Ji-Jing Pang; Vincent C. Bond; Imran Bhutto; Takayuki Baba; Gerard A. Lutty; Maria B. Grant
TAGS: choroidal neovascularization, cxcr4 receptors, insulin-like growth factor i, stromal cell-derived factor 1, vascular endothelial growth factor a, paracrine
Invest. Ophthalmol. Vis. Sci.. 2010; 51(5):2697-2704. https://doi.org/10.1167/iovs.09-4137

OSA Fall Vision Meeting Abstract December 2009

Leber Congenital Amaurosis gene therapy clinical trial

William W. Hauswirth; Artur V. Cideciyan; Tomas S. Aleman; Shalesh Kaushal; Barry J. Byrne; Sharon B. Schwartz; Sanford L. Boye; Alejandro J. Roman; Ji-jing Pang; Elizabeth A.M. Windsor; Alexander Sumaroka; Gustavo D. Aguirre; Gerald A. Fishman; Elise Heon; Terence R. Flotte; Edwin M. Stone; Samuel G. Jacobson

Journal of Vision. 2009; 9(14):27. https://doi.org/10.1167/9.14.27

Biochemistry and Molecular Biology October 2008

AAV-Mediated Gene Therapy for Retinal Degeneration in the rd10 Mouse Containing a Recessive PDEβ Mutation

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Ji-jing Pang; Sanford L. Boye; Ashok Kumar; Astra Dinculescu; Wentao Deng; Jie Li; Qiuhong Li; Asha Rani; Thomas C. Foster; Bo Chang; Norman L. Hawes; Jeffrey H. Boatright; William W. Hauswirth
TAGS: gene therapy, mice, mutation, retinal degeneration, eye, electroretinography, did not receive therapy or drug, retina
Invest. Ophthalmol. Vis. Sci.. 2008; 49(10):4278-4283. https://doi.org/10.1167/iovs.07-1622

Biochemistry and Molecular Biology October 2007

SOD2 Knockdown Mouse Model of Early AMD

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Verline Justilien; Ji-Jing Pang; Kutralanathan Renganathan; Xianquan Zhan; John W. Crabb; So Ra Kim; Janet R. Sparrow; William W. Hauswirth; Alfred S. Lewin
TAGS: catalytic rna, eye, mice, proteins, retina, photoreceptors, bruch's basal membrane, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2007; 48(10):4407-4420. https://doi.org/10.1167/iovs.07-0432

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Co-expression of human L- or M-opsin restores M-Cone Function in the Opn1mw Knock-out mouse, a model for blue cone monochromacy (BCM)

Restoration of M-cone function in an S-cone only mouse model of human blue cone monochromacy by AAV-mediated expression of human L- or M-opsin

Gene therapy in the Opn1mw Knock-out mouse, a model for blue cone monochromacy, leads to long-term M-cone restoration

Long term restoration of cone function following AAV-mediated gene therapy in CNGA3 -/- Nrl -/- Mice

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Opn1mw KO Mice

AAV-mediated Gene Therapy Restores Cone Function in the Cnga3/Nrl Double Knockout Mouse following intravitreous injection

AAV-mediated Gene Therapy Restores M-Cone Function in S-opsin only Thrb Knockout Mouse

AAV-Mediated Lysophosphatidylcholine Acyltransferase 1 ( Lpcat1 ) Gene Replacement Therapy Rescues Retinal Degeneration in rd11 Mice

AAV-mediated Lpcat1 gene replacement therapy rescues retinal degeneration in rd11 mice

AAV-mediated gene therapy restores cone function in the Cnga3/Nrl double knockout mouse

Visual Signal Pathway Reorganization in the Cacna1f Mutant Rat Model

Cone Targeted AAV-mediated Gene Therapy Restores Cone Function in the Cngb3 Knockout Mouse, a Model of Human Achromatopsia 1

AAV-mediated Cone Targeted Gene Therapy To Cpfl5 Mouse, A Model of Human Achromatopsia 2 with Mutations in Cnga3

Differential Proteomics and Functional Research Following Gene Therapy in a Mouse Model of RPE65 Leber's Congenital Amaurosis

AAV-mediated Gene Therapy Restores Cone Function in the Cngb3 Knockout Mouse, a Model of Human Achromatopsia 1

Gene Therapy Rescues Cone Structure and Function in the 3-Month-Old rd12 Mouse: A Model for Midcourse RPE65 Leber Congenital Amaurosis

Paracrine Modulation of CXCR4 by IGF-1 and VEGF: Implications for Choroidal Neovascularization

Leber Congenital Amaurosis gene therapy clinical trial

AAV-Mediated Gene Therapy for Retinal Degeneration in the rd10 Mouse Containing a Recessive PDEβ Mutation

SOD2 Knockdown Mouse Model of Early AMD

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