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Glaucoma March 2021

Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice

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Xiaowei Yu; Nannan Sun; Xue Yang; Zhenni Zhao; Xiaoqian Su; Jiamin Zhang; Yuqing He; Yixiu Lin; Jian Ge; Zhigang Fan
TAGS: mice, microphthalmos, suspensory ligament of lens, mutation, rna, messenger
Invest. Ophthalmol. Vis. Sci.. 2021; 62(3):1. doi: https://doi.org/10.1167/iovs.62.3.1

Includes: Supplemental Content

Genetics July 2019

Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study

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Congcong Guo; Zhenni Zhao; Denghui Chen; Shuxiang He; Nannan Sun; Zhongwen Li; Jiafan Liu; Dandan Zhang; Jiamin Zhang; Jianlong Li; Miao Zhang; Jian Ge; Xing Liu; Xiaoling Zhang; Zhigang Fan
TAGS: chinese (other dialects), chinese people, genetics, microphthalmos, whole genome sequencing, genes, mutation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(8):2904-2913. doi: https://doi.org/10.1167/iovs.18-26275

Includes: Supplemental Content

Articles June 2019

Posture-Dependent 24-Hour Intraocular Pressure Fluctuation Patterns in an Intraocular Hypertension Monkey Model

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Shu Tu; Kang Li; Dongpeng Hu; Kaijing Li; Jian Ge
TAGS: cercopithecidae, hypertension, intraocular pressure, posture
Trans. Vis. Sci. Tech.. 2019; 8(3):63. doi: https://doi.org/10.1167/tvst.8.3.63

Retinal Cell Biology November 2018

Self-Formation of RPE Spheroids Facilitates Enrichment and Expansion of hiPSC-Derived RPE Generated on Retinal Organoid Induction Platform

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Shengxu Liu; Bingbing Xie; Xiaojing Song; Dandan Zheng; Liwen He; Guilan Li; Guanjie Gao; Fuhua Peng; Minzhong Yu; Jian Ge; Xiufeng Zhong
TAGS: organoids, retinal pigment cell, spheroids, cellular
Invest. Ophthalmol. Vis. Sci.. 2018; 59(13):5659-5669. doi: https://doi.org/10.1167/iovs.17-23613

Includes: Supplemental Content

Cornea April 2018

Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization

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Mingjun Tang; Ying Yang; Jingzhi Yu; Jin Qiu; Pei Chen; Yihui Wu; Qiyun Wang; Zhuojun Xu; Jian Ge; Keming Yu; Jing Zhuang
TAGS: alkalies, burns, cxcr4 receptors, mice, corneal neovascularization, choroidal neovascularization
Invest. Ophthalmol. Vis. Sci.. 2018; 59(5):2133-2141. doi: https://doi.org/10.1167/iovs.17-23712

Includes: Supplemental Content

Glaucoma October 2017

Elevated Intraocular Pressure Induces Amyloid-β Deposition and Tauopathy in the Lateral Geniculate Nucleus in a Monkey Model of Glaucoma

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Zhichao Yan; Huanquan Liao; Hongrui Chen; Shuifeng Deng; Yu Jia; Caibin Deng; Jianxian Lin; Jian Ge; Yehong Zhuo
TAGS: alzheimer's disease, amyloid, glaucoma, raised intraocular pressure, tauopathies, cercopithecidae, lateral geniculate body, tau proteins, enzyme-linked immunosorbent assay
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5434-5443. doi: https://doi.org/10.1167/iovs.17-22312

Biochemistry and Molecular Biology September 2017

Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina

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Pei Chen; Xiaoxiao Cai; Ying Yang; Zhao Chen; Jin Qiu; Na Yu; Mingjun Tang; Qiyun Wang; Jian Ge; Keming Yu; Jing Zhuang
TAGS: cxcr4 receptors, retina, fibrinogen
Invest. Ophthalmol. Vis. Sci.. 2017; 58(11):4662-4669. doi: https://doi.org/10.1167/iovs.17-22115

ARVO Annual Meeting Abstract June 2017

T helper cells that co-express RORγt and Foxp3 in high-risk corneal allografts at the early stage after transplant

Zhigang Fan; Sijing Yang; Cheng Ouyang; Lijun Yang; zhuoying Feng; Ting Huang; Jian Ge

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):995. doi:

ARVO Annual Meeting Abstract June 2017

Comparative analysis of retinal differentiation of human induced pluripotent stem cells from different somatic cell sources

Xiufeng Zhong; Guilan Li; Bingbing Xie; Guanjie Gao; guangjin pan; Jian Ge

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4577. doi:

ARVO Annual Meeting Abstract September 2016

Generation of 3D retinal tissues from urine-derived hiPSCs for treatment of retinal diseases

Xiufeng Zhong; Bingbing Xie; Guilan Li; Guangjin Pan; Jian Ge

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

Retinal Cell Biology August 2015

Slit2 Promotes Angiogenic Activity Via the Robo1-VEGFR2-ERK1/2 Pathway in Both In Vivo and In Vitro Studies

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Shanshan Li; Lvzhen Huang; Yaoyao Sun; Yujing Bai; Fei Yang; Wenzhen Yu; Fangting Li; Qi Zhang; Bin Wang; Jian-Guo Geng; Xiaoxin Li
TAGS: angiogenesis, choroidal neovascularization, lasers, mice, protein overexpression, vascular endothelial growth factor receptor-2
Invest. Ophthalmol. Vis. Sci.. 2015; 56(9):5210-5217. doi: https://doi.org/10.1167/iovs-14-16184

Retinal Cell Biology October 2014

PEDF Improves Mitochondrial Function in RPE Cells During Oxidative Stress

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Yuan He; Kar Wah Leung; Yuan Ren; Jinzhi Pei; Jian Ge; Joyce Tombran-Tink
TAGS: mitochondria, oxidative stress, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6742-6755. doi: https://doi.org/10.1167/iovs.14-14696

ARVO Annual Meeting Abstract April 2014

Derivation, Characterization and Retinal Neural Induction of Human Tenon’s -Derived iPS Cells

Jian Ge; Deng Fei; Liu Ying; Xiong Yunfan

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):1365. doi:

ARVO Annual Meeting Abstract April 2014

The rate of myopia progression in children who become highly myopic

Monica Jong; Mingguang He; Brien A Holden; Wayne Li; Padmaja Sankaridurg; Xiang Chen; Thomas Navadiluth; Earl L Smith; Ian George Morgan; Jian Ge

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3636. doi:

ARVO Annual Meeting Abstract June 2013

Retinal Neuron Derived from WERI-Rb1 Improve Visual Function of RD1 and DBA/2J Mice

Jian Ge; Ying Liu; Huiling Hu; Fei Deng

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2223. doi:

ARVO Annual Meeting Abstract June 2013

Differentiation of Retinal Ganglion Cells from Induced Pluripotent Stem Cells

Binbin Xie; Xiang-Mei Zhang; Takao Hashimoto; Amy Tien; Andrew Chen; Jian Ge; Xian-Jie Yang

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2240. doi:

ARVO Annual Meeting Abstract June 2013

Correlation in Myopia Progression between right and left eyes in Chinese children with Myopia

Padmaja Sankaridurg; Brien Holden; Xiang Chen; Arthur Ho; Li Li; Leslie Donovan; Jian Ge

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):5712. doi:

ARVO Annual Meeting Abstract June 2013

Transient Upregulation and then Downregulation of BACE 1 and PS-1 in ER Stress Induced Apoptosis of Retinal Ganglion Cells in vitro

Bingqian Liu; Jian Ge

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):6114. doi:

Retina September 2012

Impacts of Hypoxia-Inducible Factor-1 Knockout in the Retinal Pigment Epithelium on Choroidal Neovascularization

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Mingkai Lin; Yang Hu; Ying Chen; Kevin K. Zhou; Ji Jin; Meili Zhu; Yun-Zheng Le; Jian Ge; Jian-xing Ma
TAGS: choroidal neovascularization, lasers, mice, hypoxia-inducible factor 1, retinal pigment epithelium, vascular endothelial growth factor a
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6197-6206. doi: https://doi.org/10.1167/iovs.11-8936

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

TMP Prevents Retinal Neovascularization and Imparts Neuroprotection in an Oxygen-Induced Retinopathy Model

Huanjiao Zhou; Yungang Ding; Shiqing Li; Gang Sun; Cheng Yang; Xifang Zhang; Liqing Wei; Jian Ge; Xiaoling Liang

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):2554. doi:

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Nanophthalmos-Associated MYRF Gene Mutation Causes Ciliary Zonule Defects in Mice

Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study

Posture-Dependent 24-Hour Intraocular Pressure Fluctuation Patterns in an Intraocular Hypertension Monkey Model

Self-Formation of RPE Spheroids Facilitates Enrichment and Expansion of hiPSC-Derived RPE Generated on Retinal Organoid Induction Platform

Tetramethylpyrazine in a Murine Alkali-Burn Model Blocks NFκB/NRF-1/CXCR4-Signaling-Induced Corneal Neovascularization

Elevated Intraocular Pressure Induces Amyloid-β Deposition and Tauopathy in the Lateral Geniculate Nucleus in a Monkey Model of Glaucoma

Nuclear Respiratory Factor-1 (NRF-1) Regulates Transcription of the CXC Receptor 4 (CXCR4) in the Rat Retina

T helper cells that co-express RORγt and Foxp3 in high-risk corneal allografts at the early stage after transplant

Comparative analysis of retinal differentiation of human induced pluripotent stem cells from different somatic cell sources

Generation of 3D retinal tissues from urine-derived hiPSCs for treatment of retinal diseases

Slit2 Promotes Angiogenic Activity Via the Robo1-VEGFR2-ERK1/2 Pathway in Both In Vivo and In Vitro Studies

PEDF Improves Mitochondrial Function in RPE Cells During Oxidative Stress

Derivation, Characterization and Retinal Neural Induction of Human Tenon’s -Derived iPS Cells

The rate of myopia progression in children who become highly myopic

Retinal Neuron Derived from WERI-Rb1 Improve Visual Function of RD1 and DBA/2J Mice

Differentiation of Retinal Ganglion Cells from Induced Pluripotent Stem Cells

Correlation in Myopia Progression between right and left eyes in Chinese children with Myopia

Transient Upregulation and then Downregulation of BACE 1 and PS-1 in ER Stress Induced Apoptosis of Retinal Ganglion Cells in vitro

Impacts of Hypoxia-Inducible Factor-1 Knockout in the Retinal Pigment Epithelium on Choroidal Neovascularization

TMP Prevents Retinal Neovascularization and Imparts Neuroprotection in an Oxygen-Induced Retinopathy Model

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