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ARVO Annual Meeting Abstract July 2019

Targeting PEDF for the treatment of experimental autoimmune uveitis

Xiaomin Zhang; Zhihui Zhang; Shuang Chen; Nu Chen; Jian-Xing (Jay) Ma; Xiaorong Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):794. doi:

ARVO Annual Meeting Abstract July 2019

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

Gennadiy P Moiseyev; Volha Malechka; Rui Cheng; Jianglei Chen; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2659. doi:

ARVO Annual Meeting Abstract July 2019

Ligand Specificities of Wnt Co-receptors in Wnt Signaling Regulation

Yusuke Takahashi; Harminder Singh; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2664. doi:

ARVO Annual Meeting Abstract July 2019

Elucidating the role of peroxisome proliferator-activated receptor alpha in diabetic keratopathy using novel in vivo and in vitro models

Amy Whelchel; Greg Matlock; Jian-Xing (Jay) Ma; Dimitrios Karamichos

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3234. doi:

ARVO Annual Meeting Abstract July 2019

Diabetes-induced down-regulation of PPARα plays a key role in the deficiency of endothelial progenitor cells and mitochondrial function

yan shao; Jianglei Chen; Xiaorong Li; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6425. doi:

ARVO Annual Meeting Abstract July 2019

Fenofibrate-loaded biodegradable nanoparticles for treating retinal neovascularization

Qingguo Xu; Fangfang Qiu; Qian Chen; Kelu Zhou; Yan Shao; Greg Matlock; Xiang Ma; Wenjing Wu; Tuo Meng; Yanhong Du; Xiang Wang; Guotao Deng; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6393. doi:

Cornea July 2018

Therapeutic Effects of a Novel Phenylphthalimide Analog for Corneal Neovascularization and Retinal Vascular Leakage

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Bing Wang; Pui-Kai Li; Jian-xing Ma; Danyang Chen
TAGS: vascular endothelial growth factor a, alkalies, eye, thalidomide, diabetes mellitus, retina, cornea, angiogenesis inhibitors, rats, streptozocin, intravitreal injections, corneal neovascularization, burns
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3630-3642. doi: 10.1167/iovs.18-24015

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

PPARalpha is required for RPE metabolism and function

Rui Cheng; Kelu Zhou; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1184. doi:

ARVO Annual Meeting Abstract July 2018

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Gennadiy P Moiseyev; Younghwa Shin; Yusuke Takahashi; Konstantin Petrukhin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5330. doi:

ARVO Annual Meeting Abstract July 2018

Distinct Roles of Wnt Co-receptors in the Regulation of Wnt Signaling in Diabetic Retinopathy

Yusuke Takahashi; Harminder Singh; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5371. doi:

Retina October 2017

Therapeutic Effects of a Novel Agonist of Peroxisome Proliferator-Activated Receptor Alpha for the Treatment of Diabetic Retinopathy

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Guotao Deng; Elizabeth P. Moran; Rui Cheng; Greg Matlock; Kelu Zhou; David Moran; Danyang Chen; Qiang Yu; Jian-Xing Ma
TAGS: apoptosis, diabetes mellitus, endothelial cells, diabetic retinopathy, in situ nick-end labeling, leukostasis, retinal neovascularization, streptozocin, mice, rats, retina, agonists, ppar alpha
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5030-5042. doi: 10.1167/iovs.16-21402

Includes: Supplemental Content

Physiology and Pharmacology October 2017

Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration

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Fangfang Qiu; Greg Matlock; Qian Chen; Kelu Zhou; Yanhong Du; Xiang Wang; Jian-Xing Ma
TAGS: choroidal neovascularization, lasers, neovascularization, pathologic, mice, agonists, exudative age-related macular degeneration, ppar alpha, exhaled nitric oxide
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5065-5075. doi: 10.1167/iovs.17-22091

Includes: Supplemental Content

Retina September 2017

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

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Mei Du; Eric Phelps; Michael J. Balangue; Aaron Dockins; Gennadiy Moiseyev; Younghwa Shin; Shelley Kane; Laura Otalora; Jian-Xing Ma; Rafal Farjo; Krysten M. Farjo
TAGS: electroretinography, mice, transgenic, retinal degeneration, retinoids, mice
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4375-4383. doi: 10.1167/iovs.17-22107

ARVO Annual Meeting Abstract June 2017

D477G dominant mutation in RPE65 leads to decreased 11- cis -retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa

Gennadiy P Moiseyev; Younghwa Shin; Dibyendu Charkraborty; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):590. doi:

ARVO Annual Meeting Abstract June 2017

PPARα in diabetic keratopathy

Greg H Matlock; Shrestha Priyadarsini; Volha Malechka; GUOTAO DENG; Fangfang Qiu; Kelu Zhou; Elizabeth P Moran; Dimitrios Karamichos; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1016. doi:

ARVO Annual Meeting Abstract June 2017

Therapeutic Effects of PPARα Agonist on Experimental Neovascular Age-Related Macular Degeneration

Fangfang Qiu; H. Greg Matlock; Qian Chen; Yanhong Du; Kelu Zhou; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1925. doi:

ARVO Annual Meeting Abstract June 2017

Role of PPAR-alpha in Retinal Mitochondrial Function

Rui Cheng; Elizabeth P Moran; Kelu Zhou; Marin Gantner; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3020. doi:

ARVO Annual Meeting Abstract June 2017

The miRNA451a/ATF2 signal pathway regulates mitochondrial function of RPE in diabetic conditions

yan shao; Lijie Dong; Yusuke Takahashi; Xun Liu; Qian Chen; Xiaorong Li; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4035. doi:

ARVO Annual Meeting Abstract June 2017

Down-Regulation of PPARα through MicroRNA-Associated Mechanism in Diabetic Retinopathy

Yusuke Takahashi; Qian Chen; Fangfang Qiu; H. Greg Matlock; Elizabeth P Moran; Raju V S Rajala; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5214. doi:

ARVO Annual Meeting Abstract June 2017

Impaired Retinoid Visual Cycle in Diabetic Retinopathy

Volha Malechka; Gennadiy P Moiseyev; Yusuke Takahashi; Younghwa Shin; Jian-Xing (Jay) Ma

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5226. doi:

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Targeting PEDF for the treatment of experimental autoimmune uveitis

Treatment of diabetic mice with chromophore improves visual function and decreases oxidative stress and apoptosis in the retina

Ligand Specificities of Wnt Co-receptors in Wnt Signaling Regulation

Elucidating the role of peroxisome proliferator-activated receptor alpha in diabetic keratopathy using novel in vivo and in vitro models

Diabetes-induced down-regulation of PPARα plays a key role in the deficiency of endothelial progenitor cells and mitochondrial function

Fenofibrate-loaded biodegradable nanoparticles for treating retinal neovascularization

Therapeutic Effects of a Novel Phenylphthalimide Analog for Corneal Neovascularization and Retinal Vascular Leakage

PPARalpha is required for RPE metabolism and function

A Novel non-Retinoid RPE65 Inhibitor CU239 Prevents Light-Induced Degeneration of the Mouse Retina through Slowing of the Visual Cycle

Distinct Roles of Wnt Co-receptors in the Regulation of Wnt Signaling in Diabetic Retinopathy

Therapeutic Effects of a Novel Agonist of Peroxisome Proliferator-Activated Receptor Alpha for the Treatment of Diabetic Retinopathy

Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration

Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration

D477G dominant mutation in RPE65 leads to decreased 11- cis -retinal generation and delayed dark-adaptation in knock-in mouse model of retinitis pigmentosa

PPARα in diabetic keratopathy

Therapeutic Effects of PPARα Agonist on Experimental Neovascular Age-Related Macular Degeneration

Role of PPAR-alpha in Retinal Mitochondrial Function

The miRNA451a/ATF2 signal pathway regulates mitochondrial function of RPE in diabetic conditions

Down-Regulation of PPARα through MicroRNA-Associated Mechanism in Diabetic Retinopathy

Impaired Retinoid Visual Cycle in Diabetic Retinopathy

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