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Retina April 2025

Nicotinamide Riboside Mitigates Retinal Degeneration by Suppressing Damaged DNA-Stimulated Microglial Activation and STING-Mediated Pyroptosis

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Shanshan Zhu; Lusi Zhang; Ping Tong; Jiawei Chen; Cong Wang; Zewei Wang; Jingyuan Liu; Peiyun Duan; Qian Jiang; Yubing Zhou; Guangshuang Tan; Xian Zhang; Bing Jiang
TAGS: dna, niacinamide, pyroptosis, retinal degeneration, retina, light exposure, mice, neuroinflammatory diseases, photoreceptors, microglia
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):14. https://doi.org/10.1167/iovs.66.4.14

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Deciphering primary-cilia-mediated signaling networks during periocular neural crest morphogenesis, specification and function

Carlo Iomini; James W Foster; Pin Lyu; Céline Portal; Varuni Rastogi; Raquel Marcenido-Larregola; Heya Lee; Jiang Qian

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4501.

ARVO Annual Meeting Abstract June 2023

Investigating gene regulatory networks controlling retinal fibrosis in a rabbit model of proliferative vitreoretinopathy

Clayton Pio Santiago; Megan Gimmen; Yuchen Lu; Leighton Duncan; Taqdees Gohar; Cornelia W Peterson; Antionette Price; Minda McNally; Tyler Creamer; Linda Orzolek; Charles G. Eberhart; Jiang Qian; Seth Blackshaw; Mandeep S Singh

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4566.

ARVO Annual Meeting Abstract June 2023

Multiomic characterization of mouse retinal aging

Isabella Palazzo; Pin Lyu; Thanh Hoang; David R Hyde; Jiang Qian; Seth Blackshaw

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):5465.

ARVO Annual Meeting Abstract June 2023

Single-nuclei RNA sequencing of the diabetic mouse retina reveals dysregulation of neurexins in early diabetic retinal disease

Mira Menon Sachdeva; Ruth Marx-Rattner; Madhu S Saddala; Shinwon Ha; Kaitlyn Clark; Dongsan Kim; Sung-Ung Kang; Jiang Qian; Valina L Dawson; Ted M Dawson

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):500.

ARVO Annual Meeting Abstract June 2023

A single cell analysis of anterior segment development focusing on Schlemm's canal

Revathi Balasubramanian; Nicholas Tolman; Taibo Li; Violet Bupp-Chickering; Aakriti Bhandari; Sally Zhou; Christa Montgomery; Jiang Qian; Simon W John

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):1847.

ARVO Annual Meeting Abstract June 2022

High content screen for small molecules that inhibit epithelial to mesenchymal transition in human stem cell-derived RPE cells

Srinivasa Sripathi; Cynthia Berlinicke; Xitiz Chamling; Rebekah Mikeasky; Yukan Duan; Caire Bell; Ming-Wen Hu; Julien Maruotti; Karl J Wahlin; Jiang Qian; Noriko Esumi; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):683 – F0137.

ARVO Annual Meeting Abstract June 2022

Single-cell RNA sequencing analysis of neurogenic competence in Müller glia in a rabbit retinal injury model

Clayton Pio Santiago; Megan Gimmen; Yuchen Lu; Ying Xin; Minda McNally; Tyler Creamer; Linda Orzolek; Thomas Zollner; William Schubert; Khaled Nassar; Charles Eberhart; Jiang Qian; Seth Blackshaw; Mandeep Singh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2653.

ARVO Annual Meeting Abstract June 2022

HDAC11 is a crucial regulator for visual cycle genes and retinal function

Peng Shang; Rachel Daley; Emma Rose Mahally; Nadezda A Stepicheva; Sayan Ghosh; Haitao Liu; Anastasiia Strizhakova; Olivia Chowdhury; Victoria Koontz; Stacey L Hose; J. Samuel Zigler; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4115 – F0352.

ARVO Annual Meeting Abstract June 2022

Pseudotime analysis of human stem cell-derived photoreceptor cell maturation following subretinal transplantation

Ying Liu; Clayton Pio Santiago; Akin Sogunro; Zheng Jiang; Gregory Konar; Ming-wen Hu; Minda McNally; Yuchen Lu; Zhuolin Li; Dzhalal Agakishiev; Sarah Hadyniak; Katarzyna Hussey; Jiang Qian; Robert Johnston; Seth Blackshaw; Mandeep Singh

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4513 – F0300.

ARVO Annual Meeting Abstract June 2021

Optical coherence tomography imaging-based evaluation of lesion characteristics in a rabbit model of proliferative vitreoretinopathy

Yuchen Lu; Ying Liu; Minda McNally; William Schubert; Melanie Adams; Jiang Qian; Seth Blackshaw; Charles Eberhart; Khaled Nassar; Mandeep S Singh

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3625.

ARVO Annual Meeting Abstract June 2021

Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of induced proliferative vitreoretinopathy

Clayton Santiago; Yuchen Lu; Minda McNally; Megan Gimmen; Thomas Zollner; William Schubert; Khaled Nassar; Charles Eberhart; Jiang Qian; Seth Blackshaw; Mandeep S Singh

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3624.

ARVO Annual Meeting Abstract June 2021

The polycomb group protein Ezh2 promotes optic nerve regeneration

Xuewei Wang; Shuguang Yang; Chi Zhang; Ming-Wen Hu; Ruiying Wang; Anish Kosanam; Jingjing Jiang; Jiang Qian; Changmei Liu; Fengquan Zhou

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3142.

Biochemistry and Molecular Biology April 2021

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE

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Srinivasa R. Sripathi; Ming-Wen Hu; Melissa M. Liu; Jun Wan; Jie Cheng; Yukan Duan; Joseph L. Mertz; Karl J. Wahlin; Julien Maruotti; Cynthia A. Berlinicke; Jiang Qian; Donald J. Zack
TAGS: epithelial to mesenchymal transition, dissociation, tumor necrosis factors, gene expression profiling
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):1. https://doi.org/10.1167/iovs.62.4.1

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Mitochondrial abnormality in astrocytes leads to optic nerve degeneration: a mechanism mediated by CXCL14

Meysam Yazdankhah; Emily G. Boxi; Stacey L Hose; Nadezda A Stepicheva; Joseph Weiss; Sayan Ghosh; Peng Shang; Haitao Liu; Christopher Scott Fitting; Ming-Wen Hu; Jiang Qian; Peter Calabresi; J. Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2791.

ARVO Annual Meeting Abstract June 2020

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Thanh Hoang; Jie Wang; Patrick Boyd; Fang Wang; Clayton Santiago; John D Ash; Andy J Fischer; David R Hyde; Jiang Qian; Seth Blackshaw

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3220.

ARVO Annual Meeting Abstract June 2020

Nuclear Factor I Regulates the Switch from Neurogenesis to Gliogenesis in the Developing Retina

Clayton Santiago; Thanh Hoang; David F Espinoza; Patrick Leavey; Jie Wang; Jiang Qian; Richard M Gronostajski; Seth Blackshaw

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4017.

ARVO Annual Meeting Abstract July 2019

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

Srinivas Rao Sripathi; Ming-Wen Hu; Jie Cheng; Melissa Liu; Yukan Duan; Jun Wan; Xue Yang; Joseph L Mertz; Cynthia Berlinicke; Julien Maruotti; Karl J Wahlin; Noriko Esumi; Jiang Qian; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1738.

ARVO Annual Meeting Abstract July 2019

Nuclear Factor I Regulates Proliferation and Specification of Müller glial and Bipolar Cells

Clayton Santiago; Thanh Hoang; David F Espinoza; Jie Wang; Jiang Qian; Richard M Gronostajski; Brian Clark; Seth Blackshaw

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3842.

ARVO Annual Meeting Abstract July 2019

Single-cell transcriptomic analysis of human NRL null retinal organoids

Donald J Zack; Alyssa Kallman; Elizabeth E. Capowski; Anu Kaushik; Liben Chen; Melissa Liu; Alex Jansen; Kim Edwards; Cindy Berlinicke; Ming-Wen Hu; Jiang Qian; Eric A Pierce; Jeff Wang; David M Gamm

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4766.

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Nicotinamide Riboside Mitigates Retinal Degeneration by Suppressing Damaged DNA-Stimulated Microglial Activation and STING-Mediated Pyroptosis

Deciphering primary-cilia-mediated signaling networks during periocular neural crest morphogenesis, specification and function

Investigating gene regulatory networks controlling retinal fibrosis in a rabbit model of proliferative vitreoretinopathy

Multiomic characterization of mouse retinal aging

Single-nuclei RNA sequencing of the diabetic mouse retina reveals dysregulation of neurexins in early diabetic retinal disease

A single cell analysis of anterior segment development focusing on Schlemm's canal

High content screen for small molecules that inhibit epithelial to mesenchymal transition in human stem cell-derived RPE cells

Single-cell RNA sequencing analysis of neurogenic competence in Müller glia in a rabbit retinal injury model

HDAC11 is a crucial regulator for visual cycle genes and retinal function

Pseudotime analysis of human stem cell-derived photoreceptor cell maturation following subretinal transplantation

Optical coherence tomography imaging-based evaluation of lesion characteristics in a rabbit model of proliferative vitreoretinopathy

Comparative analysis of single-cell and single-nucleus RNA-sequencing in a rabbit model of induced proliferative vitreoretinopathy

The polycomb group protein Ezh2 promotes optic nerve regeneration

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE

Mitochondrial abnormality in astrocytes leads to optic nerve degeneration: a mechanism mediated by CXCL14

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Nuclear Factor I Regulates the Switch from Neurogenesis to Gliogenesis in the Developing Retina

Inhibition of NF-kB signaling modulates epithelial to mesenchymal transition in human stem cell-derived retinal pigment epithelial cells

Nuclear Factor I Regulates Proliferation and Specification of Müller glial and Bipolar Cells

Single-cell transcriptomic analysis of human NRL null retinal organoids

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