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Biochemistry and Molecular Biology April 2019

PH20 Inhibits TGFβ1-Induced Differentiation of Perimysial Orbital Fibroblasts via Hyaluronan-CD44 Pathway in Thyroid-Associated Ophthalmopathy

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Ruiqi Ma; Hui Ren; Binbin Xu; Yun Cheng; Lu Gan; Rui Zhang; Jihong Wu; Jiang Qian
TAGS: fibroblasts, graves' ophthalmopathy, cd44 antigens, ovarian failure, premature, hyaluronan, homing-associated cell adhesion molecule
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1431-1441. doi: 10.1167/iovs.18-26268

Includes: Supplemental Content

Special Issue July 2018

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

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Sayan Ghosh; Peng Shang; Hiroto Terasaki; Nadezda Stepicheva; Stacey Hose; Meysam Yazdankhah; Joseph Weiss; Taiji Sakamoto; Imran A. Bhutto; Shuli Xia; J. Samuel Zigler, Jr; Ram Kannan; Jiang Qian; James T. Handa; Debasish Sinha
TAGS: crystallins, age-related macular degeneration, epithelial to mesenchymal transition, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2018; 59(4):AMD104-AMD113. doi: 10.1167/iovs.18-24132

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Liyun Zhang; Conan Chen; Jiang Qian; Hongkai Ji; Donald J Zack; Justin Hanes; David Ackerley; Baerbel Rohrer; Jeff S Mumm

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):980. doi:

ARVO Annual Meeting Abstract July 2018

Comparative transcriptomic and epigenomic analysis identifes regulators of neurogenic competence in retinal Müller glia.

Seth Blackshaw; Thanh Hoang; Jie Wang; Manuela Lahne; Levi Todd; Clayton Santiago; Nathalie Squires; Patrick Boyd; John D Ash; Andrew J Fischer; Jiang Qian; David R Hyde

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):991. doi:

ARVO Annual Meeting Abstract July 2018

Transcriptomics analysis of Muller glia in response to different damage paradigms in the adult zebrafish retina

David R Hyde; Patrick Boyd; Manuela Lahne; Thanh Hoang; Jie Wang; Clayton Santiago; Seth Blackshaw; Jiang Qian; John D Ash; Andy Fischer

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):992. doi:

ARVO Annual Meeting Abstract July 2018

Single-cell transcriptomic analysis of human and murine NRL-null retinas

Alyssa Kallman; Elizabeth E Capowski; Aniruddha M. Kaushik; Melissa Liu; Baranda S. Hansen; Liben Chen; Jie Cheng; Karl Wahlin; Ming-Wen Hu; Loyal A Goff; Jiang Qian; Cynthia Berlinicke; Jeff (Tza-Huei) Wang; David M Gamm; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3105. doi:

ARVO Annual Meeting Abstract July 2018

Müller cell transcriptional unit to regulate stress induced LIF expression

Clayton Santiago; Marcus Hooper; Thanh Hoang; Jie Wang; Jiang Qian; Seth Blackshaw; John D Ash

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2511. doi:

ARVO Annual Meeting Abstract July 2018

Epithelial to mesenchymal transition of human stem cell-derived retinal pigment epithelium cells modulates expression of axonal guidance molecules

Srinivas Rao Sripathi; Melissa M Liu; Ming-Wen Hu; Jun Wan; Jie Cheng; Joseph L Mertz; Cynthia Berlinicke; Julien Maruotti; Karl Wahlin; Jiang Qian; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4002. doi:

Cornea June 2018

Integrated Stress Response and Decreased ECM in Cultured Stromal Cells From Keratoconus Corneas

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James W. Foster; Vishal Shinde; Uri S. Soiberman; Gajanan Sathe; Sheng Liu; Julius Wan; Jiang Qian; Yassine Dauoud; Akhilesh Pandey; Albert S. Jun; Shukti Chakravarti
TAGS: cell culture techniques, stress response, collagen, keratoconus, peptides, stromal cells, cornea, proteins, keratocytes
Invest. Ophthalmol. Vis. Sci.. 2018; 59(7):2977-2986. doi: 10.1167/iovs.18-24367

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

βA3/A1-Crystallin/SLC36A4/V-ATPase complex in the RPE is a novel therapeutic target for AMD

Peng Shang; Mallika Valapala; Stacey L Hose; Jun Wan; Jiang Qian; Yuri V Sergeev; J. Samuel Zigler, Jr.; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3384. doi:

ARVO Annual Meeting Abstract June 2017

Molecular insights into ECM and collagen assembly disruptions in keratoconus

James William Foster; Vishal Shinde; Uri Soiberman; Yassine Jamil Daoud; Fares Alsaleh; Gajanan Sathe; Jun Wan; Jiang Qian; Albert S Jun; Akhilesh Pandey; Shukti Chakravarti

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3904. doi:

ARVO Annual Meeting Abstract June 2017

Single cell RNA-seq provides insights into mechanisms driving photoreceptor development and degeneration

Melissa M Liu; Ming-Wen Hu; Cynthia A Berlinicke; Jiang Qian; Loyal Goff; Donald J Zack

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4775. doi:

ARVO Annual Meeting Abstract September 2016

Pro-permeability Factors in Diabetic Macular Edema; the Diabetic Macular Edema Treated with Ozurdex (DMEO) Trial

Tahreem Aman Mir; Adrienne Scott; Lingmin He; Roomasa Channa; Catherine Mayerle; James T Handa; Saleema A. Kherani; Yong S. Han; Guohua Wang; Jiang Qian; Peter A Campochiaro

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3267. doi:

ARVO Annual Meeting Abstract September 2016

Vitreous Proteins Implicated in Idiopathic Macular Hole Formation

Sharon D Solomon; Richard Semba; Pingbo Zhang; Randi Turner; Jiang Qian; Yuming Zhao; Peter A Campochiaro; Ingrid E Zimmer-Galler; Ian Han; Yannis Mantas Paulus; Syed Mahmood Ali Shah

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4086. doi:

ARVO Annual Meeting Abstract September 2016

Glial cells of the optic nerve and Persistent Fetal Vasculature (PFV) disease

Stacey L Hose; Cheng Zhang; J Samuel Zigler; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4215. doi:

ARVO Annual Meeting Abstract September 2016

Inflammation is the Sine qua non for progression of age-related macular degeneration.

Sayan Ghosh; Peng Shang; Stacey L Hose; Jiang Qian; J Samuel Zigler; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):483. doi:

ARVO Annual Meeting Abstract June 2015

Distinct Modes of Positive and Negative Gene Expression Regulation by Tissue-specific Differential DNA Methylation

Shannath L Merbs; Jun Wan; Guohua Wang; Heng Zhu; Donald J Zack; Jiang Qian

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5504. doi:

ARVO Annual Meeting Abstract April 2014

Blood DNA Methylation Analysis Reveals Differential Methylation in AMD

Shannath L Merbs; Verity Frances Oliver; Andrew Jaffe; Anand Swaroop; Kari E Branham; Elizabeth Campochiaro; Donald J Zack; Jiang Qian

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4996. doi:

ARVO Annual Meeting Abstract April 2014

Improvement of Radiotherapy-induced lacrimal gland injury by IPS cell-derived conditioned medium via inhibition of P38/JNK pathway and cylindromatosis -dependent regulation

Yanqing Zhang; Jiang Qian; Mingui Zhang

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4614. doi:

ARVO Annual Meeting Abstract April 2014

βA3/A1-crystallin is a local mediator in astrocytes, regulating the Notch/STAT3 signaling axis

Mallika Valapala; Jian Fei Hu; J Samuel Zigler; Stacey L Hose; Eric F Wawrousek; Jiang Qian; Debasish Sinha

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2275. doi:

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PH20 Inhibits TGFβ1-Induced Differentiation of Perimysial Orbital Fibroblasts via Hyaluronan-CD44 Pathway in Thyroid-Associated Ophthalmopathy

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

Large-scale Whole-organism Phenotypic Screen Identifies Rod Cell Neuroprotectants Effective in Zebrafish and Mouse Models of Retinitis Pigmentosa

Comparative transcriptomic and epigenomic analysis identifes regulators of neurogenic competence in retinal Müller glia.

Transcriptomics analysis of Muller glia in response to different damage paradigms in the adult zebrafish retina

Single-cell transcriptomic analysis of human and murine NRL-null retinas

Müller cell transcriptional unit to regulate stress induced LIF expression

Epithelial to mesenchymal transition of human stem cell-derived retinal pigment epithelium cells modulates expression of axonal guidance molecules

Integrated Stress Response and Decreased ECM in Cultured Stromal Cells From Keratoconus Corneas

βA3/A1-Crystallin/SLC36A4/V-ATPase complex in the RPE is a novel therapeutic target for AMD

Molecular insights into ECM and collagen assembly disruptions in keratoconus

Single cell RNA-seq provides insights into mechanisms driving photoreceptor development and degeneration

Pro-permeability Factors in Diabetic Macular Edema; the Diabetic Macular Edema Treated with Ozurdex (DMEO) Trial

Vitreous Proteins Implicated in Idiopathic Macular Hole Formation

Glial cells of the optic nerve and Persistent Fetal Vasculature (PFV) disease

Inflammation is the Sine qua non for progression of age-related macular degeneration.

Distinct Modes of Positive and Negative Gene Expression Regulation by Tissue-specific Differential DNA Methylation

Blood DNA Methylation Analysis Reveals Differential Methylation in AMD

Improvement of Radiotherapy-induced lacrimal gland injury by IPS cell-derived conditioned medium via inhibition of P38/JNK pathway and cylindromatosis -dependent regulation

βA3/A1-crystallin is a local mediator in astrocytes, regulating the Notch/STAT3 signaling axis

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