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ARVO Annual Meeting Abstract June 2024

Identification of Lipocalin in Tree Shrew Tears via Top-down Proteomics

Jianzhong Chen; Mustapha El Hamdaoui; Rafael Grytz; Gordon W Laurie

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5752.

ARVO Annual Meeting Abstract June 2023

Unbiased Screening of Meibomian Lipids for Affinity to Natural C-Terminal Lacritin Proteoforms Necessary for the Prevention of Tear Film Collapse.

Jeff Romano; Georgi Georgiev; Jianzhong Chen; Marc Odrich; Gordon W Laurie

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):195.

ARVO Annual Meeting Abstract June 2022

Intact transthyretin proteoforms of intraocular origin in human subretinal fluid from rhegmatogenous retinal detachment

Jianzhong Chen; Dongfeng Cao; Seth Fortmann; Christine A Curcio; Richard Feist; Jason Crosson

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1183 – A0037.

ARVO Annual Meeting Abstract July 2019

Lipidomic Analysis of Meibomian Gland Secretions from the Tree Shrew: Identification of Candidate Tear Lipids Critical for Reducing Evaporation

Jianzhong CHEN; Shyam Panthi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4173.

ARVO Annual Meeting Abstract July 2018

Untargeted Mass Spectrometry Analysis of Lipids in Human Tears

Jianzhong CHEN; Kelly K Nichols; Jason J Nichols

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3285.

ARVO Annual Meeting Abstract July 2018

The effects of omega-6:omega-3 fatty acid ratios on the lipidome from human meibomian gland epithelial cells treated with and without 13-cis retinoic acid

Jillian F. Ziemanski; Jianzhong CHEN; Kelly K Nichols

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3810.

ARVO Annual Meeting Abstract June 2017

Chain Length and Saturation Levels of Molecular Species of Neutral Lipids in Dry Eye Patients

Jianzhong CHEN; Kelly K Nichols

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):2234.

Cornea April 2017

Expression Profiling of Nonpolar Lipids in Meibum From Patients With Dry Eye: A Pilot Study

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Jianzhong Chen; Jeremy K. Keirsey; Kari B. Green; Kelly K. Nichols
TAGS: dry eye syndromes, lipids, fasting lipid profile, pilot projects, gene expression profiling, molecular profiling
Invest. Ophthalmol. Vis. Sci.. 2017; 58(4):2266-2274. https://doi.org/10.1167/iovs.16-20902

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Evaluation of extraction and mass spectrometry methods for detection of possible lipid mediators of inflammation in tears.

Shyam Panthi; Jianzhong CHEN; Landon Wilson; Jason J Nichols

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):391.

ARVO Annual Meeting Abstract September 2016

Composition of Diesters in Human Meibum

Jianzhong CHEN; Kelly K Nichols

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4818.

ARVO Annual Meeting Abstract September 2016

Identification of lipid species produced by differentiated immortalized human meibomian gland epithelial cells

Jillian Meadows; Jianzhong CHEN; Karen Dionne; Kelly K Nichols

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5662.

ARVO Annual Meeting Abstract June 2015

Differentially Expressed Non-polar Lipids in Human Meibum of Dry Eye Disease

Jianzhong Chen; Jeremy Keirsey; Kari Basso; Kelly K Nichols

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):342.

ARVO Annual Meeting Abstract June 2015

Altered Regulation of Expressed Polar Meibum Lipids in Dry Eye Disease

Cameron K Postnikoff; Jianzhong Chen; Jeremy Keirsey; Kari Basso; Kelly K Nichols

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):343.

Biochemistry and Molecular Biology August 2013

Quantitative Profiling of Major Neutral Lipid Classes in Human Meibum by Direct Infusion Electrospray Ionization Mass Spectrometry

PDF

Jianzhong Chen; Kari B. Green; Kelly K. Nichols
TAGS: cauda equina syndrome, cesium, lipids, whole exome sequencing
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5730-5753. https://doi.org/10.1167/iovs.12-10317

Includes: Supplemental Content

ARVO Annual Meeting Abstract March 2012

Identification of Lipid Biomarkers for Dry Eye Disease In Post-Menopausal Women Using Shotgun Electrospray Mass Spectrometry

Kelly K. Nichols; Jianzhong Chen; Mark Apsega; Jason J. Nichols; Kari B. Green

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):619.

ARVO Annual Meeting Abstract April 2011

Comparison Of Mass Spectrometry Lipid Profiles Of Meibum From Dry Eye And Normal Patients Using Electrospray Ionization And Matrix-assisted Laser Desorption Ionization

Kari B. Green-Church; Jianzhong Chen; Kelly K. Nichols

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3736.

Letters to the Editor March 2011

Author Response: On the Presence of ( O -Acyl)-Omega-Hydroxy Fatty Acids and Their Esters in Human Meibomian Gland Secretions

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Jianzhong Chen; Kari B. Green-Church; Kelly K. Nichols
TAGS: bodily secretions, esters, fatty acids, meibomian gland
Invest. Ophthalmol. Vis. Sci.. 2011; 52(3):1894-1895. https://doi.org/10.1167/iovs.11-7359

Biochemistry and Molecular Biology December 2010

Shotgun Lipidomic Analysis of Human Meibomian Gland Secretions with Electrospray Ionization Tandem Mass Spectrometry

PDF

Jianzhong Chen; Kari B. Green-Church; Kelly K. Nichols
TAGS: bodily secretions, ionization, lipids, meibomian gland, tandem mass spectrometry, fatty acids, cauda equina syndrome, cesium, whole exome sequencing
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6220-6231. https://doi.org/10.1167/iovs.10-5687

Letters to the Editor December 2010

Author Response: On the Presence and Role of Polar Lipids in Meibum

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Jianzhong Chen; Kari B. Green-Church; Kelly K. Nichols
TAGS: lipids
Invest. Ophthalmol. Vis. Sci.. 2010; 51(12):6910-6911. https://doi.org/10.1167/iovs.10-6547

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Identification of Lipocalin in Tree Shrew Tears via Top-down Proteomics

Unbiased Screening of Meibomian Lipids for Affinity to Natural C-Terminal Lacritin Proteoforms Necessary for the Prevention of Tear Film Collapse.

Intact transthyretin proteoforms of intraocular origin in human subretinal fluid from rhegmatogenous retinal detachment

Lipidomic Analysis of Meibomian Gland Secretions from the Tree Shrew: Identification of Candidate Tear Lipids Critical for Reducing Evaporation

Untargeted Mass Spectrometry Analysis of Lipids in Human Tears

The effects of omega-6:omega-3 fatty acid ratios on the lipidome from human meibomian gland epithelial cells treated with and without 13-cis retinoic acid

Chain Length and Saturation Levels of Molecular Species of Neutral Lipids in Dry Eye Patients

Expression Profiling of Nonpolar Lipids in Meibum From Patients With Dry Eye: A Pilot Study

Evaluation of extraction and mass spectrometry methods for detection of possible lipid mediators of inflammation in tears.

Composition of Diesters in Human Meibum

Identification of lipid species produced by differentiated immortalized human meibomian gland epithelial cells

Differentially Expressed Non-polar Lipids in Human Meibum of Dry Eye Disease

Altered Regulation of Expressed Polar Meibum Lipids in Dry Eye Disease

Quantitative Profiling of Major Neutral Lipid Classes in Human Meibum by Direct Infusion Electrospray Ionization Mass Spectrometry

Identification of Lipid Biomarkers for Dry Eye Disease In Post-Menopausal Women Using Shotgun Electrospray Mass Spectrometry

Comparison Of Mass Spectrometry Lipid Profiles Of Meibum From Dry Eye And Normal Patients Using Electrospray Ionization And Matrix-assisted Laser Desorption Ionization

Author Response: On the Presence of ( O -Acyl)-Omega-Hydroxy Fatty Acids and Their Esters in Human Meibomian Gland Secretions

Shotgun Lipidomic Analysis of Human Meibomian Gland Secretions with Electrospray Ionization Tandem Mass Spectrometry

Author Response: On the Presence and Role of Polar Lipids in Meibum

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