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ARVO Annual Meeting Abstract June 2020

Retinal vascular density changes in metabolic dysregulated without diabetic retinopathy and age-matched normal non-human primates

Kai Ming Zhang; Jing Hua Zhu; Qiu-Yan Yang; Qin-Ming B Luo; wu jihong; Rosario B Perez; Shao-Dong B Li; Bob Zhang; Xing-Huai Sun

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1779. doi:

ARVO Annual Meeting Abstract June 2020

Retinal blood flow in metabolic dysregulated and age-matched normal non-human primates

Shenghai Zhang; Kai Ming Zhang; Jing Hua Zhu; wu jihong; Qiu-Yan Yang; Qin-Ming Luo; Rosario B Perez; Shao-Dong B Li; Bob Zhang; Xing-Huai Sun

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5419. doi:

ARVO Annual Meeting Abstract June 2020

Frequency and phenotypic characteristics of RPE65 mutation in Chinese population

fengjuan gao; wu jihong; Ge-Zhi Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2397. doi:

Glaucoma May 2020

Immediate Impact of Acute Elevation of Intraocular Pressure on Cortical Visual Motion Processing

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Nini Yuan; Mengwei Li; Xiaoxiao Chen; Yiliang Lu; Yuan Fang; Hongliang Gong; Liling Qian; Jihong Wu; Shenghai Zhang; Stewart Shipp; Ian Max Andolina; Xinghuai Sun; Wei Wang
TAGS: intraocular pressure, motion
Invest. Ophthalmol. Vis. Sci.. 2020; 61(5):59. doi: https://doi.org/10.1167/iovs.61.5.59

Biochemistry and Molecular Biology April 2019

PH20 Inhibits TGFβ1-Induced Differentiation of Perimysial Orbital Fibroblasts via Hyaluronan-CD44 Pathway in Thyroid-Associated Ophthalmopathy

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Ruiqi Ma; Hui Ren; Binbin Xu; Yun Cheng; Lu Gan; Rui Zhang; Jihong Wu; Jiang Qian
TAGS: cd44 antigens, fibroblasts, graves' ophthalmopathy, homing-associated cell adhesion molecule, hyaluronan, ovarian failure, premature
Invest. Ophthalmol. Vis. Sci.. 2019; 60(5):1431-1441. doi: https://doi.org/10.1167/iovs.18-26268

Includes: Supplemental Content

Glaucoma October 2018

Decreased d -Serine Levels Prevent Retinal Ganglion Cell Apoptosis in a Glaucomatous Animal Model

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Xuejin Zhang; Rong Zhang; Xujiao Zhou; Jihong Wu
TAGS: animal model, glaucoma, serine, apoptosis, d-serine, eye, retinal ganglion cells, retina
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):5045-5052. doi: https://doi.org/10.1167/iovs.18-24691

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Genetic deletion of NOS3 gene in CAV1 -/- mice decreases drug sensitivity to nitric oxide donor and nitric oxide synthase inhibitor

Yuan Lei; Maomao Song; Jihong Wu; Xing-Huai Sun

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1651. doi:

Glaucoma September 2017

Genetic Deletion of the NOS3 Gene in CAV1 −/− Mice Restores Aqueous Humor Outflow Function

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Maomao Song; Jihong Wu; Yuan Lei; Xinghuai Sun
TAGS: aqueous humor, mice, intraocular pressure, genetics, genes, eye
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):4976-4987. doi: https://doi.org/10.1167/iovs.16-21072

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

High pressure induces mtDNA damage and mutations and mitochondrial dysfunction in primary cultured retinal ganglion cells

Jihong Wu; Fengjuan Gao; Feng Gao; Yi Zhang; Xinghuai Sun

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6021. doi:

Glaucoma May 2016

eNOS Activity in CAV1 Knockout Mouse Eyes

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Yuan Lei; Maomao Song; Jihong Wu; Chao Xing; Xinghuai Sun
TAGS: eye, intraocular pressure, mice, nitric oxide synthase, mice, knockout, donors
Invest. Ophthalmol. Vis. Sci.. 2016; 57(6):2805-2813. doi: https://doi.org/10.1167/iovs.15-18841

Retinal Cell Biology February 2016

Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome

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Shujie Zhang; Ning Yu; Rong Zhang; Shenghai Zhang; Jihong Wu
TAGS: bodily secretions, inflammasomes, interleukin-17, retinal pigment cell, interleukins
Invest. Ophthalmol. Vis. Sci.. 2016; 57(2):312-319. doi: https://doi.org/10.1167/iovs.15-17578

Glaucoma July 2015

Aqueous Humor Outflow Physiology in NOS3 Knockout Mice

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Yuan Lei; Xuejin Zhang; Maomao Song; Jihong Wu; Xinghuai Sun

Invest. Ophthalmol. Vis. Sci.. 2015; 56(8):4891-4898. doi: https://doi.org/10.1167/iovs.15-16564

ARVO Annual Meeting Abstract June 2015

Aqueous humour outflow physiology in NOS3 knockout mice

Yuan Lei; Xuejin Zhang; Jihong Wu; Xing-Huai Sun

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):4849. doi:

Glaucoma December 2014

Endothelial Nitric Oxide Synthase–Related Mechanotransduction Changes in Aged Porcine Angular Aqueous Plexus Cells

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Yuan Lei; William Daniel Stamer; Jihong Wu; Xinghuai Sun
TAGS: mechanotransduction, cellular, nitric oxide synthase, suidae, shear stress, aging
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8402-8408. doi: https://doi.org/10.1167/iovs.14-14992

Glaucoma April 2014

Cell Senescence Reduced the Mechanotransduction Sensitivity of Porcine Angular Aqueous Plexus Cells to Elevation of Pressure

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Yuan Lei; William D. Stamer; Jihong Wu; Xinghuai Sun
TAGS: cell aging, mechanotransduction, cellular, suidae, proteins, western blotting, aging, hydrostatic pressure, cadherins, oxidative stress
Invest. Ophthalmol. Vis. Sci.. 2014; 55(4):2324-2328. doi: https://doi.org/10.1167/iovs.13-13317

Glaucoma July 2013

Oxidative Stress Impact on Barrier Function of Porcine Angular Aqueous Plexus Cell Monolayers

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Yuan Lei; William D. Stamer; Jihong Wu; Xinghuai Sun
TAGS: oxidative stress, suidae, hyperoxia, aging, galactosidase, cadherins, dna damage, endothelial cells
Invest. Ophthalmol. Vis. Sci.. 2013; 54(7):4827-4835. doi: https://doi.org/10.1167/iovs.12-11435

ARVO Annual Meeting Abstract June 2013

Somatic Epigenetic Memory in iPSC-drived from Adult RPE

Shenghai Zhang; Jihong Wu

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2224. doi:

ARVO Annual Meeting Abstract June 2013

Accumulated Increase of mtDNA Damage Contribute to Progressive Loss of RGC in a Rat Model of Glaucoma

Jihong Wu; Shenghai Zhang

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):284. doi:

ARVO Annual Meeting Abstract June 2013

Oxidative Stress Impacts On Barrier Function of Porcine Angular Aqueous Plexus Cell Monolayers

Yuan Lei; W Daniel Stamer; Jihong Wu; Xinghuai Sun

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3567. doi:

ARVO Annual Meeting Abstract June 2013

IL17A inhibits expression of POMC gene in RPE cells

Shujie Zhang; Jihong Wu; Research Center

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):143. doi:

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Retinal vascular density changes in metabolic dysregulated without diabetic retinopathy and age-matched normal non-human primates

Retinal blood flow in metabolic dysregulated and age-matched normal non-human primates

Frequency and phenotypic characteristics of RPE65 mutation in Chinese population

Immediate Impact of Acute Elevation of Intraocular Pressure on Cortical Visual Motion Processing

PH20 Inhibits TGFβ1-Induced Differentiation of Perimysial Orbital Fibroblasts via Hyaluronan-CD44 Pathway in Thyroid-Associated Ophthalmopathy

Decreased d -Serine Levels Prevent Retinal Ganglion Cell Apoptosis in a Glaucomatous Animal Model

Genetic deletion of NOS3 gene in CAV1 -/- mice decreases drug sensitivity to nitric oxide donor and nitric oxide synthase inhibitor

Genetic Deletion of the NOS3 Gene in CAV1 −/− Mice Restores Aqueous Humor Outflow Function

High pressure induces mtDNA damage and mutations and mitochondrial dysfunction in primary cultured retinal ganglion cells

eNOS Activity in CAV1 Knockout Mouse Eyes

Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome

Aqueous Humor Outflow Physiology in NOS3 Knockout Mice

Aqueous humour outflow physiology in NOS3 knockout mice

Endothelial Nitric Oxide Synthase–Related Mechanotransduction Changes in Aged Porcine Angular Aqueous Plexus Cells

Cell Senescence Reduced the Mechanotransduction Sensitivity of Porcine Angular Aqueous Plexus Cells to Elevation of Pressure

Oxidative Stress Impact on Barrier Function of Porcine Angular Aqueous Plexus Cell Monolayers

Somatic Epigenetic Memory in iPSC-drived from Adult RPE

Accumulated Increase of mtDNA Damage Contribute to Progressive Loss of RGC in a Rat Model of Glaucoma

Oxidative Stress Impacts On Barrier Function of Porcine Angular Aqueous Plexus Cell Monolayers

IL17A inhibits expression of POMC gene in RPE cells

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