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Biochemistry and Molecular Biology February 2019

DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B

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Guangying Luo; Xia Jing; Shuai Yang; Dewei Peng; Jing Dong; Li Li; Peter S. Reinach; Dongsheng Yan
TAGS: cdkn2b gene, cornea, dna, dna (cytosine-5-)-methyltransferase 1, dna methylation, epithelium, wound healing, wounds and injuries, hypermethylation, methylation
Invest. Ophthalmol. Vis. Sci.. 2019; 60(2):650-660. doi: https://doi.org/10.1167/iovs.18-25443

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Treatment with AICAR decreases intraocular pressure in perfused ex vivo human anterior segments

Ayan Chatterjee; Guadalupe Villarreal; Dong-Jin Oh; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3542. doi:

ARVO Annual Meeting Abstract June 2015

Overexpression of thrombospondin-1 (TSP1) in Human Trabecular Meshwork Alters Extracellular Matrix

Min Hyung Kang; Dong-Jin Oh; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3281. doi:

ARVO Annual Meeting Abstract June 2015

The outflow facility of SPARC KO and WT mice

Dong-Jin Oh; Ling Yu; Min Hyung Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2003. doi:

Glaucoma November 2014

Canonical Wnt Signaling Regulates Extracellular Matrix Expression in the Trabecular Meshwork

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Guadalupe Villarreal, Jr; Ayan Chatterjee; Sarah S. Oh; Dong-Jin Oh; Min Hyung Kang; Douglas J. Rhee
TAGS: extracellular matrix, lithium chloride, proteins, signal transduction, trabecular meshwork, dominant-negative mutation, family, intraocular pressure, micrornas, immunoblotting
Invest. Ophthalmol. Vis. Sci.. 2014; 55(11):7433-7440. doi: https://doi.org/10.1167/iovs.13-12652

Includes: Supplemental Content

Glaucoma July 2014

TGF-β2–Mediated Ocular Hypertension Is Attenuated in SPARC-Null Mice

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Swarup S. Swaminathan; Dong-Jin Oh; Min Hyung Kang; Allan R. Shepard; Iok-Hou Pang; Douglas J. Rhee
TAGS: attenuation, intraocular pressure, mice, ocular hypertension, sparc study, eye, fibronectins, proteins
Invest. Ophthalmol. Vis. Sci.. 2014; 55(7):4084-4097. doi: https://doi.org/10.1167/iovs.13-12463

Glaucoma May 2014

AMP-Activated Protein Kinase Regulates Intraocular Pressure, Extracellular Matrix, and Cytoskeleton in Trabecular Meshwork

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Ayan Chatterjee; Guadalupe Villarreal, Jr.; Dong-Jin Oh; Min Hyung Kang; Douglas J. Rhee
TAGS: aica ribonucleotide, ampk, aqueous humor, cytoskeleton, extracellular matrix, homeostasis, intraocular pressure, mice, protein kinase, proteins
Invest. Ophthalmol. Vis. Sci.. 2014; 55(5):3127-3139. doi: https://doi.org/10.1167/iovs.13-12755

ARVO Annual Meeting Abstract April 2014

Incubation with SPARC mitigates MMP-2-mediated collagen 4 degradation in vitro

Ayan Chatterjee; Min Kang; Dong-Jin Oh; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5685. doi:

ARVO Annual Meeting Abstract April 2014

Trafficking of SPARC

Dong-Jin Oh; Min Kang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5686. doi:

ARVO Annual Meeting Abstract April 2014

Functional analysis of peptides from Secreted Protein, Acidic and Rich in Cysteine (SPARC).

Min Hyung Kang; Dong-Jin Oh; Douglas J Rhee; Glaucoma

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5687. doi:

ARVO Annual Meeting Abstract April 2014

In vivo study of the role of SPARC in TGFb2-mediated ocular hypertension

Swarup Sai Swaminathan; Dong-Jin Oh; Min Kang; Allan R Shepard; Iok-Hou Pang; Douglas J Rhee

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5987. doi:

Glaucoma March 2014

Pharmacological Regulation of SPARC by Lovastatin in Human Trabecular Meshwork Cells

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Guadalupe Villarreal, Jr; Ayan Chatterjee; Sarah S. Oh; Dong-Jin Oh; Douglas J. Rhee
TAGS: lovastatin, sparc study, statins, trabecular meshwork, pharmacology
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1657-1665. doi: https://doi.org/10.1167/iovs.13-12712

Glaucoma August 2013

The Effects of Tenascin C Knockdown on Trabecular Meshwork Outflow Resistance

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Kate E. Keller; Janice A. Vranka; Ramez I. Haddadin; Min-Hyung Kang; Dong-Jin Oh; Douglas J. Rhee; Yong-feng Yang; Ying Ying Sun; Mary J. Kelley; Ted S. Acott
TAGS: tenascin, trabecular meshwork, proteins, rna, messenger, eye
Invest. Ophthalmol. Vis. Sci.. 2013; 54(8):5613-5623. doi: https://doi.org/10.1167/iovs.13-11620

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2013

Overexpression of SPARC Upregulates Gremlin and Proteoglycans Opticin & Decorin

Swarup Swaminathan; Dong-Jin Oh; Douglas Rhee

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3549. doi:

ARVO Annual Meeting Abstract June 2013

Latanoprost Lowers Intraocular Pressure in Matrix Metalloproteinase 9-null Mice

Ramez Haddadin; Dong-Jin Oh; Douglas Rhee

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):789. doi:

Glaucoma May 2013

Overexpression of SPARC in Human Trabecular Meshwork Increases Intraocular Pressure and Alters Extracellular Matrix

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Dong-Jin Oh; Min Hyung Kang; Yen Hoong Ooi; Kyu Ryong Choi; E. Helene Sage; Douglas J. Rhee
TAGS: protein overexpression, sparc study, intraocular pressure, proteins
Invest. Ophthalmol. Vis. Sci.. 2013; 54(5):3309-3319. doi: https://doi.org/10.1167/iovs.12-11362

Biochemistry and Molecular Biology April 2013

Regulation of SPARC by Transforming Growth Factor β2 in Human Trabecular Meshwork

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Min Hyung Kang; Dong-Jin Oh; Ja-heon Kang; Douglas J. Rhee
TAGS: sparc study, trabecular meshwork, up-regulation (physiology), transforming growth factor alpha, transforming growth factors, regulation, smad3 gene, proteins
Invest. Ophthalmol. Vis. Sci.. 2013; 54(4):2523-2532. doi: https://doi.org/10.1167/iovs.12-11474

Glaucoma March 2013

Secreted Protein Acidic and Rich in Cysteine (SPARC)-Null Mice Exhibit More Uniform Outflow

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Swarup S. Swaminathan; Dong-Jin Oh; Min Hyung Kang; Ruiyi Ren; Rui Jin; Haiyan Gong; Douglas J. Rhee
TAGS: body tissue, cysteine, eye, intraocular pressure, mice, microspheres, proteins, sparc study, collagen
Invest. Ophthalmol. Vis. Sci.. 2013; 54(3):2035-2047. doi: https://doi.org/10.1167/iovs.12-10950

Glaucoma September 2012

Thrombospondin-1 (TSP1)–Null and TSP2-Null Mice Exhibit Lower Intraocular Pressures

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Ramez I. Haddadin; Dong-Jin Oh; Min Hyung Kang; Guadalupe Villarreal, Jr; Ja-Heon Kang; Rui Jin; Haiyan Gong; Douglas J. Rhee
TAGS: intraocular pressure, mice, thrombospondin 1
Invest. Ophthalmol. Vis. Sci.. 2012; 53(10):6708-6717. doi: https://doi.org/10.1167/iovs.11-9013

ARVO Annual Meeting Abstract March 2012

Effect of Excess Complement Activation on AMD-like Pathology in the APOE4/cfh Knockout Transgenic Murine Model: Does Loss-of-function Exacerbate Retinal Disease?

Joseph G. Christenbury; Jin-Dong Ding; Una Kelly; Marybeth Groelle; Catherine Bowes Rickman

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1641. doi:

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DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B

Treatment with AICAR decreases intraocular pressure in perfused ex vivo human anterior segments

Overexpression of thrombospondin-1 (TSP1) in Human Trabecular Meshwork Alters Extracellular Matrix

The outflow facility of SPARC KO and WT mice

Canonical Wnt Signaling Regulates Extracellular Matrix Expression in the Trabecular Meshwork

TGF-β2–Mediated Ocular Hypertension Is Attenuated in SPARC-Null Mice

AMP-Activated Protein Kinase Regulates Intraocular Pressure, Extracellular Matrix, and Cytoskeleton in Trabecular Meshwork

Incubation with SPARC mitigates MMP-2-mediated collagen 4 degradation in vitro

Trafficking of SPARC

Functional analysis of peptides from Secreted Protein, Acidic and Rich in Cysteine (SPARC).

In vivo study of the role of SPARC in TGFb2-mediated ocular hypertension

Pharmacological Regulation of SPARC by Lovastatin in Human Trabecular Meshwork Cells

The Effects of Tenascin C Knockdown on Trabecular Meshwork Outflow Resistance

Overexpression of SPARC Upregulates Gremlin and Proteoglycans Opticin & Decorin

Latanoprost Lowers Intraocular Pressure in Matrix Metalloproteinase 9-null Mice

Overexpression of SPARC in Human Trabecular Meshwork Increases Intraocular Pressure and Alters Extracellular Matrix

Regulation of SPARC by Transforming Growth Factor β2 in Human Trabecular Meshwork

Secreted Protein Acidic and Rich in Cysteine (SPARC)-Null Mice Exhibit More Uniform Outflow

Thrombospondin-1 (TSP1)–Null and TSP2-Null Mice Exhibit Lower Intraocular Pressures

Effect of Excess Complement Activation on AMD-like Pathology in the APOE4/cfh Knockout Transgenic Murine Model: Does Loss-of-function Exacerbate Retinal Disease?

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