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ARVO Annual Meeting Abstract June 2025

Implication of SerpinA3 in the Pathogenesis of Graves’ Orbitopathy

Dongheon Surl; Min Seok Kim; Soo Hyun Choi; Jaesang Ko; Sun Young Jang; Jin Sook Yoon

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):4295.

Biochemistry and Molecular Biology May 2025

Nicotinamide N-Methyltransferase in the Inflammatory Pathogenesis of Graves’ Orbitopathy

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Dayoon Cho; Soo Hyun Choi; Jin Sook Yoon; JaeSang Ko
TAGS: cytokine, fibroblasts, inflammation, methyltransferase, niacinamide, pathogenesis, body tissue, western blotting, cyclooxygenase-2
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):3. https://doi.org/10.1167/iovs.66.5.3

Includes: Supplemental Content

Immunology and Microbiology April 2025

Role of SerpinA3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

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Min Seok Kim; Soo Hyun Choi; Hyun Young Park; Sun Young Jang; JaeSang Ko; Jae-woo Kim; Jin Sook Yoon
TAGS: body tissue, fibroblasts, pathogenesis, hyaluronan
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):20. https://doi.org/10.1167/iovs.66.4.20

Includes: Supplemental Content

Biochemistry and Molecular Biology November 2024

Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

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Seung Hyun Park; Soo Hyun Choi; Hyun Young Park; JaeSang Ko; Jin Sook Yoon
TAGS: body tissue, fibroblasts, oxidase, pathogenesis, proteins
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):33. https://doi.org/10.1167/iovs.65.13.33

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Therapeutic effect of nintedanib, a triple angiokinase inhibitor in the pathogenesis of Graves’ orbitopathy

Hyun Young Park; Soo Hyun Choi; JaeSang Ko; Jin Sook Yoon

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3039.

Biochemistry and Molecular Biology August 2023

The Role of Adipsin, Complement Factor D, in the Pathogenesis of Graves’ Orbitopathy

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Hyeong Ju Byeon; Min Kyung Chae; JaeSang Ko; Eun Jig Lee; Don O. Kikkawa; Sun Young Jang; Jin Sook Yoon
TAGS: complement factor d, fibroblasts, pathogenesis
Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):13. https://doi.org/10.1167/iovs.64.11.13

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

The Effect of Rho-Kinase Inhibitors on In-Vitro Human Orbital Preadipocytes

Meredith Horacek; David Yoo; Jin Sook Yoon; Ping Bu; Min Kyung Chae; Ji Young Kim

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):4055.

Biochemistry and Molecular Biology June 2022

Potential Therapeutic Role of Bone Morphogenic Protein 7 (BMP7) in the Pathogenesis of Graves’ Orbitopathy

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Bo Yi Kim; Soo Hyun Choi; Ji-Young Kim; JaeSang Ko; Jong In Yook; Hyun Sil Kim; Eun Jig Lee; Don O. Kikkawa; Jin Sook Yoon
TAGS: body tissue, bone morphogenetic proteins, fibroblasts, molecule, pathogenesis, proteins, tumor necrosis factors, western blotting, cytokine, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2022; 63(6):7. https://doi.org/10.1167/iovs.63.6.7

Includes: Supplemental Content

Glaucoma December 2021

The Effect of CHIR 99021, a Glycogen Synthase Kinase-3β Inhibitor, on Transforming Growth Factor β-Induced Tenon Fibrosis

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Sang Yeop Lee; Min Kyoung Chae; Jin Sook Yoon; Chan Yun Kim
TAGS: fibrosis, glycogen (starch) synthase, phosphotransferases, transforming growth factors, glaucoma
Invest. Ophthalmol. Vis. Sci.. 2021; 62(15):25. https://doi.org/10.1167/iovs.62.15.25

Includes: Supplemental Content

Biochemistry and Molecular Biology July 2020

Glycogen Synthase Kinase-3β Mediates Proinflammatory Cytokine Secretion and Adipogenesis in Orbital Fibroblasts from Patients with Graves’ Orbitopathy

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Jihei Sara Lee; Min Kyoung Chae; Don O. Kikkawa; Eun Jig Lee; Jin Sook Yoon
TAGS: cytokine, fibroblasts, glycogen (starch) synthase, phosphotransferases, bodily secretions, body tissue, adipocytes
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):51. https://doi.org/10.1167/iovs.61.8.51

Includes: Supplemental Content

Biochemistry and Molecular Biology March 2020

Therapeutic Effect of Guggulsterone in Primary Cultured Orbital Fibroblasts Obtained From Patients with Graves’ Orbitopathy

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Bo Ram Kim; Jinjoo Kim; Jong Eun Lee; Eun Jig Lee; Jin Sook Yoon
TAGS: fibroblasts, hyaluronan
Invest. Ophthalmol. Vis. Sci.. 2020; 61(3):39. https://doi.org/10.1167/iovs.61.3.39

Includes: Supplemental Content

Biochemistry and Molecular Biology October 2019

Therapeutic Effect of Curcumin, a Plant Polyphenol Extracted From Curcuma longae , in Fibroblasts From Patients With Graves' Orbitopathy

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Jihei Sara Lee; Jinjoo Kim; Eun Jig Lee; Jin Sook Yoon
TAGS: curcumin, fibroblasts, polyphenols, plants
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4129-4140. https://doi.org/10.1167/iovs.19-27376

Biochemistry and Molecular Biology September 2018

Inhibitory Effect of Idelalisib, a Selective Phosphatidylinositol 3-Kinase δ Inhibitor, on Adipogenesis in an In Vitro Model of Graves' Orbitopathy

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JaeSang Ko; Ji-Young Kim; Eun Jig Lee; Jin Sook Yoon
TAGS: 1-phosphatidylinositol 3-kinase, fibroblasts, idelalisib
Invest. Ophthalmol. Vis. Sci.. 2018; 59(11):4477-4485. https://doi.org/10.1167/iovs.18-24509

Includes: Supplemental Content

Biochemistry and Molecular Biology May 2017

Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy

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JaeSang Ko; Min Kyoung Chae; Joon H. Lee; Eun Jig Lee; Jin Sook Yoon
TAGS: fibroblasts, fibrosis, proteins, sphingosine-1-phosphate phosphatase, western blotting
Invest. Ophthalmol. Vis. Sci.. 2017; 58(5):2544-2553. https://doi.org/10.1167/iovs.16-20684

Includes: Supplemental Content

Letters to the Editor December 2016

Author Response: Role of miR-146a in the Regulation of Inflammation in an In Vitro Model of Graves' Orbitopathy

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Sun Young Jang; Jin Sook Yoon
TAGS: inflammation, regulation
Invest. Ophthalmol. Vis. Sci.. 2016; 57(15):6796. https://doi.org/10.1167/iovs.16-20847

ARVO Annual Meeting Abstract September 2016

SURGICAL OUTCOMES OF PORCINE ACELLULAR DERMIS GRAFT IN SOCKET AND EYELID RECONSTRUCTION: A COMPARISON WITH ORAL MUCOSAL GRAFT

Livia Teo; Chang Yeom Kim; Dong Kyu Kim; Jin Sook Yoon

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):684.

ARVO Annual Meeting Abstract September 2016

Clinical Features of Graves Orbitopathy Patients with Recurred Orbital Inflammation after Decompression

Young Jun Woo; Do Wook Kim; Ji Won Kim; Jin Sook Yoon

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):701.

ARVO Annual Meeting Abstract September 2016

Association between Graves’ orbitopathy and ocular hypertension prevalence

Ji Won Kim; Young Jun Woo; Jin Sook Yoon

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4557.

Biochemistry and Molecular Biology August 2016

Role of miR-146a in the Regulation of Inflammation in an In Vitro Model of Graves' Orbitopathy

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Sun Young Jang; Min Kyung Chae; Joon H. Lee; Eun Jig Lee; Jin Sook Yoon
TAGS: fibroblasts, inflammation, interleukin-6, proteins, regulation, micrornas, intercellular adhesion molecule 1
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4027-4034. https://doi.org/10.1167/iovs.16-19213

Biochemistry and Molecular Biology August 2016

Therapeutic Effect of Protocatechuic Aldehyde in an In Vitro Model of Graves' Orbitopathy

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Jung Woo Byun; Sena Hwang; Chan Woo Kang; Jin Hee Kim; Min Kyung Chae; Jin Sook Yoon; Eun Jig Lee
TAGS: aldehydes, fibroblasts, hyaluronan, tumor necrosis factors, western blotting, proteins, enzyme-linked immunosorbent assay, antioxidants, peroxisome proliferator-activated receptors
Invest. Ophthalmol. Vis. Sci.. 2016; 57(10):4055-4062. https://doi.org/10.1167/iovs.15-19037

Includes: Supplemental Content

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Implication of SerpinA3 in the Pathogenesis of Graves’ Orbitopathy

Nicotinamide N-Methyltransferase in the Inflammatory Pathogenesis of Graves’ Orbitopathy

Role of SerpinA3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

Role of Lysyl Oxidase-Like Protein 3 in the Pathogenesis of Graves’ Orbitopathy in Orbital Fibroblasts

Therapeutic effect of nintedanib, a triple angiokinase inhibitor in the pathogenesis of Graves’ orbitopathy

The Role of Adipsin, Complement Factor D, in the Pathogenesis of Graves’ Orbitopathy

The Effect of Rho-Kinase Inhibitors on In-Vitro Human Orbital Preadipocytes

Potential Therapeutic Role of Bone Morphogenic Protein 7 (BMP7) in the Pathogenesis of Graves’ Orbitopathy

The Effect of CHIR 99021, a Glycogen Synthase Kinase-3β Inhibitor, on Transforming Growth Factor β-Induced Tenon Fibrosis

Glycogen Synthase Kinase-3β Mediates Proinflammatory Cytokine Secretion and Adipogenesis in Orbital Fibroblasts from Patients with Graves’ Orbitopathy

Therapeutic Effect of Guggulsterone in Primary Cultured Orbital Fibroblasts Obtained From Patients with Graves’ Orbitopathy

Therapeutic Effect of Curcumin, a Plant Polyphenol Extracted From Curcuma longae , in Fibroblasts From Patients With Graves' Orbitopathy

Inhibitory Effect of Idelalisib, a Selective Phosphatidylinositol 3-Kinase δ Inhibitor, on Adipogenesis in an In Vitro Model of Graves' Orbitopathy

Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy

Author Response: Role of miR-146a in the Regulation of Inflammation in an In Vitro Model of Graves' Orbitopathy

SURGICAL OUTCOMES OF PORCINE ACELLULAR DERMIS GRAFT IN SOCKET AND EYELID RECONSTRUCTION: A COMPARISON WITH ORAL MUCOSAL GRAFT

Clinical Features of Graves Orbitopathy Patients with Recurred Orbital Inflammation after Decompression

Association between Graves’ orbitopathy and ocular hypertension prevalence

Role of miR-146a in the Regulation of Inflammation in an In Vitro Model of Graves' Orbitopathy

Therapeutic Effect of Protocatechuic Aldehyde in an In Vitro Model of Graves' Orbitopathy

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