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ARVO Annual Meeting Abstract June 2025

Upregulation of TGF-β1 from macrophages and canonical Wnt pathway leads to conjunctival keratinocytes loss in Sjögren's syndrome related dry eye

Lihong Liang; Bowen Wang; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2025; 66(8):1568.

Cornea May 2025

Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye

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Runze Zhang; Lihong Liang; Kai Liao; Hao Zeng; Xue Yang; Xiaoran Wang; Bowen Wang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, stress, autophagy, western blotting, impairment
Invest. Ophthalmol. Vis. Sci.. 2025; 66(5):23. https://doi.org/10.1167/iovs.66.5.23

Includes: Supplemental Content

Immunology and Microbiology April 2025

Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-β-Wnt/β-Catenin Signaling in Sjögren’s Syndrome Related Dry Eye

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Bowen Wang; Lihong Liang; Hao Zeng; Xue Yang; Runze Zhang; Wenrui Deng; Xiaoran Wang; Jin Yuan
TAGS: conjunctiva, dry eye syndromes, keratinocytes, sequence analysis, rna, signal transduction, sjogren's syndrome, rna, t-lymphocytes
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):43. https://doi.org/10.1167/iovs.66.4.43

Includes: Supplemental Content

Immunology and Microbiology January 2025

Piezo1 Enhances Macrophage Phagocytosis and Pyrin Activation to Ameliorate Fungal Keratitis

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Jiahui Yang; Jing Zhong; Zhenyuan Fu; Dalian He; Jing Zhang; Jin Yuan
TAGS: cornea, fungal keratitis, infections, macrophages, marenostrin, mice, phagocytosis, proteins, mycoses, mass or substance concentration per volume
Invest. Ophthalmol. Vis. Sci.. 2025; 66(1):33. https://doi.org/10.1167/iovs.66.1.33

Includes: Supplemental Content

Cornea December 2024

Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease

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Xin Zuo; Hao Zeng; Xue Yang; Dalian He; Bowen Wang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, loeys-dietz syndrome, proteins, stress, western blotting, autophagy, lipid peroxidation, lysosomes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(14):12. https://doi.org/10.1167/iovs.65.14.12

Includes: Supplemental Content

Cornea October 2024

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

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Liqiong Zhu; Chaoqun Chen; Siqi Wu; Huizhen Guo; Lingyu Li; Li Wang; Dongmei Liu; Yu Zhan; Xinyue Du; Jiafeng Liu; Jieying Tan; Ying Huang; Kunlun Mo; Xihong Lan; Hong Ouyang; Jin Yuan; Xiangjun Chen; Jianping Ji
TAGS: cornea, homeostasis, pax6 transcription factor, scirrhous adenocarcinoma, epithelium, chronic exertional compartment syndrome, genes
Invest. Ophthalmol. Vis. Sci.. 2024; 65(12):40. https://doi.org/10.1167/iovs.65.12.40

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Disruption of sphingolipid homeostasis promotes the progression of fungal keratitis

zhenyuan Fu; Jing Zhong; Jiahui Yang; Jing Zhang; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2907.

Public Health June 2024

The Myopia Prevalence and Association With Physical Activity Among Primary School Students Aged 6–12 Years: A Cross-Sectional Study in Tianjin, China

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Fei Ma; Jing Yang; Jing Yuan; Bei Du; Tongtong Li; Qi Wu; Jing Yan; Yun Zhu; Xiangda Meng; Yuanyuan Liu; Ruihua Wei; Guowei Huang; Hua Yan
TAGS: myopia, physical activity, prevalence, school (environment), china, student
Trans. Vis. Sci. Tech.. 2024; 13(6):4. https://doi.org/10.1167/tvst.13.6.4

Cornea January 2024

KCNK5 Regulating Potassium Efflux and Inducing Pyroptosis in Corneal Epithelial Cells Through TNFSF10-Mediated Autophagy in Dry Eye

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Kai Liao; Hao Zeng; Xue Yang; Dalian He; Bowen Wang; Jin Yuan
TAGS: autophagy, corneal epithelial cells, dry eye syndromes, potassium, pyroptosis, tnf-related apoptosis-inducing ligand, mice
Invest. Ophthalmol. Vis. Sci.. 2024; 65(1):34. https://doi.org/10.1167/iovs.65.1.34

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2023

Atg5-mediated lipophagy induces lipid droplets catabolism and promotes ferroptosis in corneal epithelial cells in dry eye disease

Xin Zuo; Bowen Wang; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2023; 64(8):678.

Cornea March 2023

IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye

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Xue Yang; Xin Zuo; Hao Zeng; Kai Liao; Dalian He; Bowen Wang; Jin Yuan
TAGS: cornea, corneal epithelial cells, dry eye syndromes, pyroptosis, stat1 gene, stress, mice, fluorescent antibody technique, interferon type ii
Invest. Ophthalmol. Vis. Sci.. 2023; 64(3):34. https://doi.org/10.1167/iovs.64.3.34

Includes: Supplemental Content

Cornea September 2022

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

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Xin Zuo; Hao Zeng; Bowen Wang; Xue Yang; Dalian He; Li Wang; Hong Ouyang; Jin Yuan
TAGS: corneal epithelial cells, dry eye syndromes, ferroptosis, stress
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):3. https://doi.org/10.1167/iovs.63.10.3

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2022

Hyaluronic Acid based Therapeutic Bandage Contact Lenses for Corneal Wound Healing

Jennifer Jing Yuan Tian; Lina Liu; Mitchell Ross; Heather Sheardown

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3222 – A0257.

ARVO Annual Meeting Abstract June 2022

Preclinical evaluation of RTC-1119, a surface eroding intracameral implant composed entirely of a latanoprost acid prodrug, for long-term intraocular pressure control

Ike Ahmed; Kyle Battiston; Shadi Taghavi; Hans Fischer; Emily Baldwin; Matthew Statham; Jonathan Day; Adam Daley; Ben Muirhead; Emily Anne Hicks; Jennifer Jing Yuan Tian; Heather Sheardown; Ian Parrag; Wendy Naimark

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):442.

ARVO Annual Meeting Abstract June 2020

Melatonin Ameliorates Oxidative Stress-mediated Injuries through Induction of HO-1 and Restores Autophagic Flux in Dry Eye

BOWEN WANG; LULU PENG; Xiaoran Wang; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1958.

ARVO Annual Meeting Abstract July 2019

The Visual Quality and its Related Life Quality of Pterygium

Jin Yuan; zhong jing; Zhong-Lin Lu; Fang Hou; Michael Dorr; Zhipeng Chen; Shenglan Zhang; Jinrong Li

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):4469.

ARVO Annual Meeting Abstract July 2019

In vivo Wavefront-correctionless Full-field OCT Human Retinal Imaging

Peng XIAO; Pedro Mecê; Viacheslav Mazlin; Mathias Fink; Claude Boccara; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1274.

ARVO Annual Meeting Abstract July 2019

Tear cytokines and conjunctival microvascular alterations in dry eye patients in responses to anti-inflammation treatment

YUQING DENG; Jianhua Wang; Hong Jiang; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):6735.

ARVO Annual Meeting Abstract July 2019

DDIT4 regulates impaired autophagy through oxidative stress in dry eye

BOWEN WANG; Xiaoran Wang; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2816.

ARVO Annual Meeting Abstract July 2019

Perceptual learning along the “weaker” principal meridian improves contrast sensitivity function and visual acuity in patients with astigmatism

Li Gu; Jinrong Li; zhong jing; Zhipeng Chen; Shenglan Zhang; Zhong-Lin Lu; Jin Yuan

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5900.

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Upregulation of TGF-β1 from macrophages and canonical Wnt pathway leads to conjunctival keratinocytes loss in Sjögren's syndrome related dry eye

Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye

Single-Cell RNA Sequencing Revealed Functional Conjunctival Keratinocytes Loss via TGF-β-Wnt/β-Catenin Signaling in Sjögren’s Syndrome Related Dry Eye

Piezo1 Enhances Macrophage Phagocytosis and Pyrin Activation to Ameliorate Fungal Keratitis

Atg5-Mediated Lipophagy Induces Ferroptosis in Corneal Epithelial Cells in Dry Eye Disease

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

Disruption of sphingolipid homeostasis promotes the progression of fungal keratitis

The Myopia Prevalence and Association With Physical Activity Among Primary School Students Aged 6–12 Years: A Cross-Sectional Study in Tianjin, China

KCNK5 Regulating Potassium Efflux and Inducing Pyroptosis in Corneal Epithelial Cells Through TNFSF10-Mediated Autophagy in Dry Eye

Atg5-mediated lipophagy induces lipid droplets catabolism and promotes ferroptosis in corneal epithelial cells in dry eye disease

IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye

AKR1C1 Protects Corneal Epithelial Cells Against Oxidative Stress-Mediated Ferroptosis in Dry Eye

Hyaluronic Acid based Therapeutic Bandage Contact Lenses for Corneal Wound Healing

Preclinical evaluation of RTC-1119, a surface eroding intracameral implant composed entirely of a latanoprost acid prodrug, for long-term intraocular pressure control

Melatonin Ameliorates Oxidative Stress-mediated Injuries through Induction of HO-1 and Restores Autophagic Flux in Dry Eye

The Visual Quality and its Related Life Quality of Pterygium

In vivo Wavefront-correctionless Full-field OCT Human Retinal Imaging

Tear cytokines and conjunctival microvascular alterations in dry eye patients in responses to anti-inflammation treatment

DDIT4 regulates impaired autophagy through oxidative stress in dry eye

Perceptual learning along the “weaker” principal meridian improves contrast sensitivity function and visual acuity in patients with astigmatism

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