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Biochemistry and Molecular Biology September 2022

RO4929097, a Selective γ-Secretase Inhibitor, Inhibits Subretinal Fibrosis Via Suppressing Notch and ERK1/2 Signaling in Laser-Induced Mouse Model

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Chaoyang Zhang; Shiyue Qin; Hai Xie; Qinghua Qiu; Haiyan Wang; Jingting Zhang; Dawei Luo; Jingfa Zhang
TAGS: choroidal neovascularization, epithelial to mesenchymal transition, fibrosis, lasers, mice, signal transduction
Invest. Ophthalmol. Vis. Sci.. 2022; 63(10):14. https://doi.org/10.1167/iovs.63.10.14

Includes: Supplemental Content

Articles May 2022

Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma

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Ke Shi; Xinxin Li; Jingfa Zhang; Xiaodong Sun
TAGS: genes, intraocular melanoma, metabolism, patient prognosis
Trans. Vis. Sci. Tech.. 2022; 11(5):9. https://doi.org/10.1167/tvst.11.5.9

Includes: Supplemental Content

Retinal Cell Biology April 2021

Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

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Yi Chen; Binxin Wu; Jian Feng He; Jingyao Chen; Zi Wei Kang; Dandan Liu; Junjie Luo; Kexin Fang; Xiaoxu Leng; Haibin Tian; Jingying Xu; Caixia Jin; Jieping Zhang; Juan Wang; Jingfa Zhang; Qingjian Ou; Lixia Lu; Furong Gao; Guo-Tong Xu
TAGS: epithelial to mesenchymal transition, retinal pigment cell, signal transduction inhibitor, primary eosinophilic endomyocardial cardiomyopathy
Invest. Ophthalmol. Vis. Sci.. 2021; 62(4):21. https://doi.org/10.1167/iovs.62.4.21

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2020

Transplantation site affects the outcome of adipose-derived stem cell-based therapy for retinal degeneration

Haibin Tian; Furong Gao; Caixia Jin; Jing-Ying Xu; Juan Wang; Jieping Zhang; Jingfa Zhang; Lixia LYU; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):803.

ARVO Annual Meeting Abstract June 2020

The proteomic profiles in aqueous humor of patients with neovascular age-related macular degeneration.

Tong Li; Jingfa Zhang; Xiaodong Sun

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5007.

Retinal Cell Biology February 2020

Protein Kinase A Inhibitor H89 Attenuates Experimental Proliferative Vitreoretinopathy

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Yali Lyu; Wei Xu; Jieping Zhang; Mengwen Li; Qingyi Xiang; Yao Li; Tianhao Tan; Qingjian Ou; Jingfa Zhang; Haibin Tian; Jing-Ying Xu; Caixia Jin; Furong Gao; Juan Wang; Weiye Li; Ao Rong; Lixia Lu; Guo-Tong Xu
TAGS: attenuation, cyclic amp-dependent protein kinases, epithelial to mesenchymal transition, gel, proteins, tissue membrane, vitreoretinopathy, proliferative, collagen, pathogenesis, rats
Invest. Ophthalmol. Vis. Sci.. 2020; 61(2):1. https://doi.org/10.1167/iovs.61.2.1

Includes: Supplemental Content

Retinal Cell Biology December 2019

The Interplay Between E-Cadherin, Connexin 43, and Zona Occludens 1 in Retinal Pigment Epithelial Cells

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Huiqian Bao; Shuai Yang; Hui Li; Haipei Yao; Yao Zhang; Jingfa Zhang; Guotong Xu; Haiying Jin; Fang Wang
TAGS: connexin 43, e-cadherin, herpes zoster disease
Invest. Ophthalmol. Vis. Sci.. 2019; 60(15):5104-5111. https://doi.org/10.1167/iovs.19-27768

ARVO Annual Meeting Abstract July 2019

Ranibizumab prevents Müller cell edema in diabetic retinopathy

Jingfa Zhang; Tianqin Wang; Chaoyang Zhang; Hai xie; Qiuxue Yi; Dandan Liu; Qing Peng; Weiye Li; Guo-Tong Xu; Lin Liu

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2653.

ARVO Annual Meeting Abstract July 2018

A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells

Haibin Tian; Jing-Ying Xu; Caixia Jin; Furong Gao; Juan Wang; Jieping Zhang; Jingfa Zhang; Weiye Li; Lixia Lu; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3093.

ARVO Annual Meeting Abstract July 2018

Erythropoietin Protects Retinal Pigment Epithelium in Experimental Diabetic Retinopathy

Chaoyang Zhang; Hai Xie; Yiting Yang; Qian Yang; Haibin Tian; Lixia Lu; Weiye Li; Jingfa Zhang; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5359.

ARVO Annual Meeting Abstract June 2017

Erythropoietin Protects Outer Blood–Retina Barrier in Experimental Diabetic Retina Through Up-regulating ZO-1 and occludin

Jingfa Zhang; Chaoyang Zhang; Qian Yang; Weiye Li; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5208.

ARVO Annual Meeting Abstract June 2017

Fucoidan Inhibits Epithelial-Mesenchymal Transition of Retinal Pigment Epithelium in Proliferative Vitreoretinopathy

Yao Zhang; Hui Li; Shuai Yang; Haipei Yao; Jingfa Zhang; Guo-Tong Xu; Fang Wang

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):5976.

ARVO Annual Meeting Abstract September 2016

EPO protects BRB through down-regulating ICAM-1 and up-regulating VE-cadherin in diabetic retinopathy

Jingfa Zhang; Qian Yang; Chaoyang Zhang; Weiye Li; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):5418.

Biochemistry and Molecular Biology December 2015

Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression

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Guoxu Xu; Daohuan Kang; Chaoyang Zhang; Hui Lou; Chen Sun; Qian Yang; Lixia Lu; Guo-Tong Xu; Jingfa Zhang; Fang Wang
TAGS: diabetes mellitus, erythropoietin, retina, zinc, rats, proteins, digoxin
Invest. Ophthalmol. Vis. Sci.. 2015; 56(13):8166-8178. https://doi.org/10.1167/iovs.15-18093

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2015

EPO maintains zinc homeostasis by upregulation of zinc transporter 8 (ZnT8) in diabetic rats

Guo-Tong Xu; Daohuan Kang; Jingfa Zhang; Lixia Lu; Haibin Tian; Weiye Li; Guoxu Xu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5193.

ARVO Annual Meeting Abstract June 2015

E PO protects BRB via inhibition of VEGF/VEGFR2-VE-cadherin in diabetic retinopathy

Jingfa Zhang; Hua Xu; Lixia Lu; Haibin Tian; Weiye Li; Guo-Tong Xu

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):5198.

Retina December 2014

Erythropoietin Exerts a Neuroprotective Function Against Glutamate Neurotoxicity in Experimental Diabetic Retina

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Limin Gu; Hua Xu; Fang Wang; Guoxu Xu; Debasish Sinha; Juan Wang; Jing-Ying Xu; Haibin Tian; Furong Gao; Weiye Li; Lixia Lu; Jingfa Zhang; Guo-Tong Xu
TAGS: diabetes mellitus, erythropoietin, glutamate, glutamates, neurotoxicity syndromes, retina, toxic effect, proteins
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8208-8222. https://doi.org/10.1167/iovs.14-14435

Includes: Supplemental Content

Biochemistry and Molecular Biology July 2014

Fullerenol Protects Retinal Pigment Epithelial Cells From Oxidative Stress–Induced Premature Senescence via Activating SIRT1

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Chun-Chun Zhuge; Jing-Ying Xu; Jingfa Zhang; Weiye Li; Peng Li; Zongyi Li; Ling Chen; Xiaoqing Liu; Peng Shang; Hua Xu; Yanjun Lu; Fang Wang; Lixia Lu; Guo-Tong Xu
TAGS: aging, older adult, oxidative stress, retinal pigment cell, dna damage
Invest. Ophthalmol. Vis. Sci.. 2014; 55(7):4628-4638. https://doi.org/10.1167/iovs.13-13732

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Dysfunctional Microglial Cells as a Contributory Factor to Diabetic Macular Edema

Behnaz Rouhani; Mansi Patel; Jingfa Zhang; Guotong Xu; Weiye Li

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):4424.

Retina March 2014

Subretinal Delivery of AAV2-Mediated Human Erythropoietin Gene Is Protective and Safe in Experimental Diabetic Retinopathy

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Hua Xu; Limei Zhang; Limin Gu; Lixia Lu; Guangping Gao; Weiye Li; Guoxu Xu; Juan Wang; Furong Gao; Jing-Ying Xu; Jun Yao; Fang Wang; Jingfa Zhang; Guo-Tong Xu
TAGS: cytomegalovirus, cytomegalovirus infections, rats, retina, diabetic retinopathy, erythropoietin
Invest. Ophthalmol. Vis. Sci.. 2014; 55(3):1519-1530. https://doi.org/10.1167/iovs.13-13155

Includes: Supplemental Content

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RO4929097, a Selective γ-Secretase Inhibitor, Inhibits Subretinal Fibrosis Via Suppressing Notch and ERK1/2 Signaling in Laser-Induced Mouse Model

Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma

Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors

Transplantation site affects the outcome of adipose-derived stem cell-based therapy for retinal degeneration

The proteomic profiles in aqueous humor of patients with neovascular age-related macular degeneration.

Protein Kinase A Inhibitor H89 Attenuates Experimental Proliferative Vitreoretinopathy

The Interplay Between E-Cadherin, Connexin 43, and Zona Occludens 1 in Retinal Pigment Epithelial Cells

Ranibizumab prevents Müller cell edema in diabetic retinopathy

A cell culture condition that induces the mesenchymal-epithelial transition of dedifferentiated porcine retinal pigment epithelial cells

Erythropoietin Protects Retinal Pigment Epithelium in Experimental Diabetic Retinopathy

Erythropoietin Protects Outer Blood–Retina Barrier in Experimental Diabetic Retina Through Up-regulating ZO-1 and occludin

Fucoidan Inhibits Epithelial-Mesenchymal Transition of Retinal Pigment Epithelium in Proliferative Vitreoretinopathy

EPO protects BRB through down-regulating ICAM-1 and up-regulating VE-cadherin in diabetic retinopathy

Erythropoietin Protects Retinal Cells in Diabetic Rats Through Upregulating ZnT8 via Activating ERK Pathway and Inhibiting HIF-1α Expression

EPO maintains zinc homeostasis by upregulation of zinc transporter 8 (ZnT8) in diabetic rats

E PO protects BRB via inhibition of VEGF/VEGFR2-VE-cadherin in diabetic retinopathy

Erythropoietin Exerts a Neuroprotective Function Against Glutamate Neurotoxicity in Experimental Diabetic Retina

Fullerenol Protects Retinal Pigment Epithelial Cells From Oxidative Stress–Induced Premature Senescence via Activating SIRT1

Dysfunctional Microglial Cells as a Contributory Factor to Diabetic Macular Edema

Subretinal Delivery of AAV2-Mediated Human Erythropoietin Gene Is Protective and Safe in Experimental Diabetic Retinopathy

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