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ARVO Annual Meeting Abstract June 2022

Neuroprotection of retinal ganglion cells using two vector approach for expression of TrkB receptor and agonist ligand

Henry Chen; Adrianna Latuszek; Ying Hu; Brijeshkumar Patel; Gaurang Patel; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):972 – F0369. doi:

ARVO Annual Meeting Abstract June 2022

Differential expression of complement genes in mammalian eyes

Hua Yang; Ming Yuan; Patel Gaurang; Aixu Sun; Adrianna Latuszek; Ying Hu; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4594 – F0386. doi:

ARVO Annual Meeting Abstract June 2021

Intravitreal administration, but not systemic administration, of VEGF Mini-Trap effectively inhibits neovascularization in the Oxygen Induced Retinopathy (OIR) in mice

Eunice Cheung; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3293. doi:

ARVO Annual Meeting Abstract June 2021

Retinal structural and functional rescue by subretinal delivery of RS1 gene in mouse models of X-linked juvenile retinoschisis

Yang Liu; Duo Sun; Shireen Khattak; Jingtai Cao; Romano Romano

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1467. doi:

ARVO Annual Meeting Abstract June 2020

Cas9 and AAV Vector-Based Strategies for X-linked Juvenile Retinoschisis (XLRS) Therapy

Yang Liu; Charleen Hunt; Duo Sun; Shireen Khattak; Timothy Hanna; Clarissa Herman; Lynn Lee; Katie Huling; Tara Liao; Jingtai Cao; Guochun Gong; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):800. doi:

ARVO Annual Meeting Abstract June 2020

Disrupted spontaneous calcium signals in the glia and neurons in the developing retinoschisin-deficient retina

Cyril Eleftheriou; Carlo Corona; Paola Bianchimano; Elena Ivanova; Yang Lin; Duo Sun; Jingtai Cao; Carl Romano; Botir T Sagdullaev

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1060. doi:

ARVO Annual Meeting Abstract June 2020

Potassium Voltage-gated channel, Isk-related family 3 (Kcne3) is a novel tip cell marker that plays a role in normal retinal vascular development and revascularization in the Oxygen Induced Retinopathy (OIR) model in mice.

Eunice Cheung; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2231. doi:

ARVO Annual Meeting Abstract June 2020

Ocular distribution of AAV variants after intravitreal and intracameral injections in mouse

Adrianna Latuszek; Hua Yang; Ming Yuan; Henry Chen; Brijeshkumar Patel; Gaurang Patel; Ying Hu; Jingtai Cao; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2467. doi:

ARVO Annual Meeting Abstract June 2020

In situ hybridization of human trabecular meshwork tissues shows localization of cell-type specific expression of genes identified by scRNA-seq

Hua Yang; Gaurang Patel; Wen Fury; Ming Yuan; Ying Hu; Jingtai Cao; Daniel Stamer; Carl Romano

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3422. doi:

ARVO Annual Meeting Abstract June 2020

Intravitreal Half-lives of Aflibercept and Brolucizumab in Rabbit Measured Using In Vivo Fluorophotometry

Carl Romano; Tara Liao; Antonio Luz; Ashique Rafique; Krunal Patel; Duo Sun; Yang Liu; Jingtai Cao

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4926. doi:

ARVO Annual Meeting Abstract July 2019

Intravitreal injection of NPR1 antibody in humanized NPR1 mice lowers intraocular pressure

Ming Yuan; Hua Yang; Gaurang Patel; Adrianna Latuszek; Ying Hu; William Poueymirou; Jingtai Cao; William Olson; Brian Zambrowicz; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):3771. doi:

ARVO Annual Meeting Abstract July 2019

Systemic anti- IL6R antibody administration limits infiltrating leukocytes in pericyte depletion model in mice.

Eunice Cheung; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):243. doi:

ARVO Annual Meeting Abstract July 2018

Aflibercept in combination with nesvacumab (anti-Ang2) induces vascular remodeling in a rabbit model of pathological neovascularization.

Bibiana Iglesias; Thomas MacPherson; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1447. doi:

ARVO Annual Meeting Abstract July 2018

Effect of Anti-Human C5 Antibodies on Ocular Inflammation in Experimental Autoimmune Uveitis in Humanized C5 Mice Aixu Sun, Henry Chen, Hua Yang, Adrianna Latuszek, Ying Hu, Pamela Krueger, Tammy Huang, Jingtai Cao, Carmelo Romano Regeneron Pharmaceuticals, Inc. Tarrytown, NY

Aixu Sun; Henry Chen; Hua Yang; Adrianna Latuszek; Ying Hu; Pamela Krueger; Tammy Huang; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):2534. doi:

ARVO Annual Meeting Abstract July 2018

Wild Type and Mutant Retinoschisin Subunits Co-assemble When Expressed in the Same Cells

Duo Sun; Yang Liu; Nicole Zazzarino; Jifang Tao; Joel Martin; William Olson; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3050. doi:

ARVO Annual Meeting Abstract July 2018

VEGFR1 inhibition hinders developmental retinal vessel outgrowth in pups and reduces pathological neovascularization in OIR model in mice

Eunice Cheung; Jingtai Cao; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5461. doi:

ARVO Annual Meeting Abstract July 2018

Analysis of VEGF expression in a chronic model of retinal neovascularization.

Carl Romano; Bibiana Iglesias; Jingtai Cao

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5482. doi:

ARVO Annual Meeting Abstract July 2018

Neuroprotective effect of TrkB agonist antibody in humanized TrkB rat

Henry Chen; Adrianna Latuszek; Ying Hu; Jeffrey Lee; William Poueymirou; Jingtai Cao; William Olson; Brian Zambrowicz; Carmelo Romano

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6134. doi:

Retina February 2018

Aflibercept Action in a Rabbit Model of Chronic Retinal Neovascularization: Reversible Inhibition of Pathologic Leakage With Dose-Dependent Duration

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Jingtai Cao; Thomas C. MacPherson; Bibiana V. Iglesias; Yang Liu; Natasha Tirko; George D. Yancopoulos; Stanley J. Wiegand; Carmelo Romano
TAGS: aflibercept, eye, injections, oryctolagus cuniculus, retinal neovascularization, diagnostic imaging, anti-vascular endothelial growth factor therapy
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):1033-1044. doi: https://doi.org/10.1167/iovs.17-22897

ARVO Annual Meeting Abstract June 2017

Functional and Morphological Characteristics of Three Mouse Models for X-Linked Juvenile Retinoschisis

Junzo Kinoshita; Yang Liu; Jingtai Cao; Brent A Bell; Carl Romano; Neal S Peachey

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):276. doi:

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Neuroprotection of retinal ganglion cells using two vector approach for expression of TrkB receptor and agonist ligand

Differential expression of complement genes in mammalian eyes

Intravitreal administration, but not systemic administration, of VEGF Mini-Trap effectively inhibits neovascularization in the Oxygen Induced Retinopathy (OIR) in mice

Retinal structural and functional rescue by subretinal delivery of RS1 gene in mouse models of X-linked juvenile retinoschisis

Cas9 and AAV Vector-Based Strategies for X-linked Juvenile Retinoschisis (XLRS) Therapy

Disrupted spontaneous calcium signals in the glia and neurons in the developing retinoschisin-deficient retina

Potassium Voltage-gated channel, Isk-related family 3 (Kcne3) is a novel tip cell marker that plays a role in normal retinal vascular development and revascularization in the Oxygen Induced Retinopathy (OIR) model in mice.

Ocular distribution of AAV variants after intravitreal and intracameral injections in mouse

In situ hybridization of human trabecular meshwork tissues shows localization of cell-type specific expression of genes identified by scRNA-seq

Intravitreal Half-lives of Aflibercept and Brolucizumab in Rabbit Measured Using In Vivo Fluorophotometry

Intravitreal injection of NPR1 antibody in humanized NPR1 mice lowers intraocular pressure

Systemic anti- IL6R antibody administration limits infiltrating leukocytes in pericyte depletion model in mice.

Aflibercept in combination with nesvacumab (anti-Ang2) induces vascular remodeling in a rabbit model of pathological neovascularization.

Effect of Anti-Human C5 Antibodies on Ocular Inflammation in Experimental Autoimmune Uveitis in Humanized C5 Mice Aixu Sun, Henry Chen, Hua Yang, Adrianna Latuszek, Ying Hu, Pamela Krueger, Tammy Huang, Jingtai Cao, Carmelo Romano Regeneron Pharmaceuticals, Inc. Tarrytown, NY

Wild Type and Mutant Retinoschisin Subunits Co-assemble When Expressed in the Same Cells

VEGFR1 inhibition hinders developmental retinal vessel outgrowth in pups and reduces pathological neovascularization in OIR model in mice

Analysis of VEGF expression in a chronic model of retinal neovascularization.

Neuroprotective effect of TrkB agonist antibody in humanized TrkB rat

Aflibercept Action in a Rabbit Model of Chronic Retinal Neovascularization: Reversible Inhibition of Pathologic Leakage With Dose-Dependent Duration

Functional and Morphological Characteristics of Three Mouse Models for X-Linked Juvenile Retinoschisis

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