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Retinal Cell Biology September 2017

Viral Retinopathy in Experimental Models of Zika Infection

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Zhenyang Zhao; Matthew Yang; Sasha R. Azar; Lynn Soong; Scott C. Weaver; Jiaren Sun; Yan Chen; Shannan L. Rossi; Jiyang Cai
TAGS: retinal diseases, body tissue, infection, eye, mice, retina, rna, zika virus, zika virus disease
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4355-4365. doi: 10.1167/iovs.17-22016

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Multifunctional small molecule TLR4 antagonist for treating ocular neovascularization

Suchismita Acharya; Santosh K Panda; Jiyang Cai; Dorota L Stankowska

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):201. doi:

ARVO Annual Meeting Abstract September 2016

Interleukin-17 (IL-17) in Models of Retinal and RPE Degeneration

Jiyang Cai; Jianbin Chen; Pei Xu; Zhen-Yang Zhao; Yingzi Cong; Yan Chen

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Protective Roles of γδT-Cells in Model of RPE Injury

Zhen-Yang Zhao; Pei Xu; Valentina Reffatto; Yuejin Liang; Jiaren Sun; Yan Chen; Deming Sun; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):477. doi:

Retinal Cell Biology December 2014

Subcellular Distribution and Activity of Mechanistic Target of Rapamycin in Aged Retinal Pigment Epithelium

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Bo Yu; Pei Xu; Zhenyang Zhao; Jiyang Cai; Paul Sternberg; Yan Chen
TAGS: aging, signal transduction, western blotting, amino acids, rapamycin, culture media, lysosomes, mice, proteins, mtor serine-threonine kinases, retinal pigment epithelium, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2014; 55(12):8638-8650. doi: 10.1167/iovs.14-14758

Includes: Supplemental Content

Retinal Cell Biology October 2014

γδ T Cells as a Major Source of IL-17 Production During Age-Dependent RPE Degeneration

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Zhenyang Zhao; Pei Xu; Zuliang Jie; Yiqin Zuo; Bo Yu; Lynn Soong; Jiaren Sun; Yan Chen; Jiyang Cai
TAGS: heart failure, diet, interleukin-17, lymphocyte, microglia, t-lymphocyte, eye, mice, retina, tissue degeneration
Invest. Ophthalmol. Vis. Sci.. 2014; 55(10):6580-6589. doi: 10.1167/iovs.14-15166

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

T Cells Infiltration and RPE Degeneration in NRF2-deficient Mice Fed with High Fat, Cholesterol-Rich Diet

Zhen-Yang Zhao; Pei Xu; Yiqin Zuo; Bo Yu; Bo Long; Yan Chen; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):75. doi:

ARVO Annual Meeting Abstract April 2014

Dissecting molecular pathways of mTORC1 signaling in the retinal pigment epithelium

Bo Yu; Pei Xu; Zhen-Yang Zhao; Bo Long; Jiyang Cai; Yan Chen

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3443. doi:

ARVO Annual Meeting Abstract April 2014

Age-dependent changes in clearance of phagocytosed photoreceptor outer segments in the Retinal Pigment Epithelium

Pei Xu; Zhen-Yang Zhao; Bo Yu; Bo Long; Jiyang Cai; Yan Chen

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3448. doi:

ARVO Annual Meeting Abstract June 2013

Macrophage Activation by RPE-Derived Exosomes

Yiqin Zuo; Zhen-Yang Zhao; Pei Xu; Bo Yu; Yan Chen; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):342. doi:

ARVO Annual Meeting Abstract June 2013

Functional Interactions between Autophagy and Phagocytosis Pathways in ARPE-19 cells

Pei Xu; Zhen-Yang Zhao; Bo Yu; Yiqin Zuo; Jiyang Cai; Yan Chen

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):343. doi:

ARVO Annual Meeting Abstract June 2013

Increased Fundus Autofluorescence and Retinal Cell Infiltration in Middle-Aged Mice Fed with High Fat, Cholesterol-Rich Diet

Zhen-Yang Zhao; Yiqin Zuo; Pei Xu; Bo Yu; Massoud Motamedi; Adam Boretsky; Yan Chen; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):161. doi:

ARVO Annual Meeting Abstract March 2012

Exosomal Export In RPE Cells With Lysosome Inhibition

Zhen-Yang Zhao; Yan Chen; Jian Wang; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1147. doi:

ARVO Annual Meeting Abstract April 2011

Regulation of Autophagy by Nrf2 in Retinal Pigment Epithelium

Yan Chen; Zhen-Yang Zhao; Paul Sternberg, Jr.; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2311. doi:

ARVO Annual Meeting Abstract April 2011

Biomarkers of Oxidative Stress and Genetic Variants in Age-related Macular Degeneration

Milam A. Brantley, Jr.; Jiyang Cai; Melissa P. Osborn; Barton J. Sanders; Pengcheng Lu; Chun Li; Jonathan L. Haines; Paul Sternberg, Jr.

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3068. doi:

ARVO Annual Meeting Abstract April 2011

Short-term Effects of Antioxidant Supplements on Oxidative Stress Biomarker Levels

Melissa P. Osborn; Milam A. Brantley, Jr.; Kasra A. Rezaei; Barton J. Sanders; Jiyang Cai; Paul Sternberg, Jr.

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):4007. doi:

ARVO Annual Meeting Abstract April 2011

Age-dependent Retinal Changes in Nrf-2 Knockout Mice Similar to Cardinal Features of Age-related Macular Degeneration

Zhen-Yang Zhao; Yan Chen; Jian Wang; Hans E. Grossniklaus; Paul Sternberg, Jr.; Jiyang Cai

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):952. doi:

Retina February 2011

Reduced Choroidal Neovascular Membrane Formation in Cyclooxygenase-2 Null Mice

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Kasra A. Rezaei; Hassanain S. Toma; Jiyang Cai; John S. Penn; Paul Sternberg; Stephen J. Kim
TAGS: tumor necrosis factors, cyclooxygenase-2, vascular endothelial growth factor a, choroidal neovascularization, lasers, light coagulation, mice, knockout, cyclooxygenase-2 inhibitors
Invest. Ophthalmol. Vis. Sci.. 2011; 52(2):701-707. doi: 10.1167/iovs.10-6319

Retinal Cell Biology October 2010

Altered mTOR Signaling in Senescent Retinal Pigment Epithelium

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Yan Chen; Jian Wang; Jiyang Cai; Paul Sternberg
TAGS: aging, signal transduction, mtor serine-threonine kinases, retinal pigment epithelium, retinal pigment cell
Invest. Ophthalmol. Vis. Sci.. 2010; 51(10):5314-5319. doi: 10.1167/iovs.10-5280

Retinal Cell Biology February 2009

Phosphatidylinositol 3 Kinase Pathway and 4-Hydroxy-2-Nonenal-Induced Oxidative Injury in the RPE

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Jianbin Chen; Ling Wang; Yan Chen; Paul Sternberg; Jiyang Cai
TAGS: 1-phosphatidylinositol 3-kinase, wounds and injuries, proteins
Invest. Ophthalmol. Vis. Sci.. 2009; 50(2):936-942. doi: 10.1167/iovs.08-2439

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Viral Retinopathy in Experimental Models of Zika Infection

Multifunctional small molecule TLR4 antagonist for treating ocular neovascularization

Interleukin-17 (IL-17) in Models of Retinal and RPE Degeneration

Protective Roles of γδT-Cells in Model of RPE Injury

Subcellular Distribution and Activity of Mechanistic Target of Rapamycin in Aged Retinal Pigment Epithelium

γδ T Cells as a Major Source of IL-17 Production During Age-Dependent RPE Degeneration

T Cells Infiltration and RPE Degeneration in NRF2-deficient Mice Fed with High Fat, Cholesterol-Rich Diet

Dissecting molecular pathways of mTORC1 signaling in the retinal pigment epithelium

Age-dependent changes in clearance of phagocytosed photoreceptor outer segments in the Retinal Pigment Epithelium

Macrophage Activation by RPE-Derived Exosomes

Functional Interactions between Autophagy and Phagocytosis Pathways in ARPE-19 cells

Increased Fundus Autofluorescence and Retinal Cell Infiltration in Middle-Aged Mice Fed with High Fat, Cholesterol-Rich Diet

Exosomal Export In RPE Cells With Lysosome Inhibition

Regulation of Autophagy by Nrf2 in Retinal Pigment Epithelium

Biomarkers of Oxidative Stress and Genetic Variants in Age-related Macular Degeneration

Short-term Effects of Antioxidant Supplements on Oxidative Stress Biomarker Levels

Age-dependent Retinal Changes in Nrf-2 Knockout Mice Similar to Cardinal Features of Age-related Macular Degeneration

Reduced Choroidal Neovascular Membrane Formation in Cyclooxygenase-2 Null Mice

Altered mTOR Signaling in Senescent Retinal Pigment Epithelium

Phosphatidylinositol 3 Kinase Pathway and 4-Hydroxy-2-Nonenal-Induced Oxidative Injury in the RPE

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