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ARVO Annual Meeting Abstract July 2018

Substrate stiffness triggers an extracellular matrix response in human trabecular meshwork cells and tissues

Janice A Vranka; Julia Staverosky; Ying Ying Sun; Yong-Feng Yang; John Bradley; Kate E Keller; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):4722. doi:

Glaucoma October 2017

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells

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Kate E. Keller; John M. Bradley; Ying Ying Sun; Yong-Feng Yang; Ted S. Acott
TAGS: actins, mitochondria, cd44 antigens, cellular structures, dimethyl sulfoxide, microscopy, confocal, software, body tissue, trabecular meshwork, diagnostic imaging, vesicle, homing-associated cell adhesion molecule, transfer technique
Invest. Ophthalmol. Vis. Sci.. 2017; 58(12):5298-5307. doi: 10.1167/iovs.17-22732

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

The role of Myosin-X in tunneling nanotube formation by trabecular meshwork cells

Kate E Keller; John Bradley; Ying Ying Sun; Yong-feng Yang; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4691. doi:

ARVO Annual Meeting Abstract September 2016

Novel extracellular protein kinases Fam20A and Fam20C differentially distribute with MMP14 at PILS in TM cells

Mini Aga; Samuel J Berk; John M Bradley; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4701. doi:

ARVO Annual Meeting Abstract June 2015

Unidirectional transfer of cellular cargo between trabecular meshwork cells via novel actin-based filopodia

Kate E Keller; John M Bradley; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3265. doi:

ARVO Annual Meeting Abstract June 2015

Matrix metalloproteinase-14 dimerization orchestrates matrix degradation at podosome- or invadopodia-like structures (PILS) in trabecular meshwork.

Mini Aga; John M Bradley; Ted S Acott

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3283. doi:

ARVO Annual Meeting Abstract June 2015

Conjunctival gene expression differences between aqueous-deficient and evaporative dry eye patients relative to controls

Roderick J Fullard; John L Bradley

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):347. doi:

Glaucoma September 2014

Differential Effects of Caveolin-1 and -2 Knockdown on Aqueous Outflow and Altered Extracellular Matrix Turnover in Caveolin-Silenced Trabecular Meshwork Cells

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Mini Aga; John M. Bradley; Rohan Wanchu; Yong-feng Yang; Ted S. Acott; Kate E. Keller
TAGS: extracellular matrix, fibronectins, caveolins, genes, lentivirus, matrix metalloproteinases, perfusion, trabecular meshwork, proteins, catabolism
Invest. Ophthalmol. Vis. Sci.. 2014; 55(9):5497-5509. doi: 10.1167/iovs.14-14519

Includes: Supplemental Content

ARVO Annual Meeting Abstract April 2014

Correlations between non-stimulated tear levels and conjunctival gene expression of MAPK pathway-associated biomarkers in aqueous-deficient dry eye and control patients

Roderick J Fullard; Nicole M Guyette; My-Tho K Tran; John L Bradley

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):3683. doi:

ARVO Annual Meeting Abstract June 2013

Caveolins modulate ECM turnover by Trabecular Meshwork cells

Mini Aga; Kate Keller; John Bradley; Ted Acott

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3560. doi:

ARVO Annual Meeting Abstract June 2013

Correlations between non-stimulated tear levels and conjunctival surface expression of inflammation-related biomarkers in normal and aqueous-deficient dry eye patients

Roderick Fullard; John Bradley; Larezia Williams; My-Tho Tran; Nicole Guyette; Tammy Than; Pearl Shin

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4360. doi:

Cornea May 2013

Comparison of Low-Abundance Biomarker Levels in Capillary-Collected Nonstimulated Tears and Washout Tears of Aqueous-Deficient and Normal Patients

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Nicole Guyette; Larezia Williams; My-Tho Tran; Tammy Than; John Bradley; Lucy Kehinde; Clara Edwards; Mark Beasley; Roderick Fullard
TAGS: cytokine, biological markers, dry eye syndromes, blood capillaries
Invest. Ophthalmol. Vis. Sci.. 2013; 54(5):3729-3737. doi: 10.1167/iovs.12-11431

Glaucoma July 2012

Perturbation of Hyaluronan Synthesis in the Trabecular Meshwork and the Effects on Outflow Facility

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Kate E. Keller; Ying Ying Sun; Yong-Feng Yang; John M. Bradley; Ted S. Acott
TAGS: western blotting, enzyme-linked immunosorbent assay, gene silencing, genes, lentivirus, perfusion, rna, messenger, suidae, body tissue, trabecular meshwork, eye, proteins, mass or substance concentration per volume, hyaluronan, quantitative real-time polymerase chain reaction, perturbations
Invest. Ophthalmol. Vis. Sci.. 2012; 53(8):4616-4625. doi: 10.1167/iovs.12-9500

ARVO Annual Meeting Abstract March 2012

Conjunctival Gene Expression Patterns in Dry Eye; Real Time PCR and Beyond

John L. Bradley; Keshia S. Elder; Tammy P. Than; Roderick J. Fullard

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):538. doi:

ARVO Annual Meeting Abstract March 2012

Non-stimulated Tear Levels and Conjunctival Expression of IL-8 and IP-10 in Normal and Dry Eye Patients

Roderick J. Fullard; My-Tho K. Tran; Larezia D. Williams; John L. Bradley; Nicole M. Guyette; Tammy P. Than; Roy Joseph; Landon S. Wilson; Stephen Barnes

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):539. doi:

ARVO Annual Meeting Abstract March 2012

Dynasore - A Dynamin Inhibitor Alters Outflow Facility and Endosomal Uptake in Trabecular Meshwork Cells

John M. Bradley; Mini Aga; Ted S. Acott

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3238. doi:

ARVO Annual Meeting Abstract March 2012

Gleevec Alters Endosomal Arrangement at PILS and Inhibits Extracellular Matrix (ECM) Degradation in Trabecular Meshwork Cells

Mini Aga; John M. Bradley; Mary J. Kelley; Ted S. Acott

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3251. doi:

Glaucoma September 2011

Molecular Chaperone Function for Myocilin

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Ann Marie Anderssohn; Kalani Cox; Kevin O'Malley; Scott Dees; Mojgan Hosseini; Lacey Boren; Anthony Wagner; John M. Bradley; Mary J. Kelley; Ted S. Acott
TAGS: citrate (si)-synthase, molecular chaperones, myoc gene
Invest. Ophthalmol. Vis. Sci.. 2011; 52(10):7548-7555. doi: 10.1167/iovs.11-7723

Glaucoma July 2011

Segmental Versican Expression in the Trabecular Meshwork and Involvement in Outflow Facility

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Kate E. Keller; John M. Bradley; Janice A. Vranka; Ted S. Acott
TAGS: immunohistochemistry, fluorescent antibody technique, glycosaminoglycans, lentivirus, microscopy, confocal, perfusion, proteoglycan, rna, messenger, suidae, trabecular meshwork, infection, aqueous humor, enzymes, eye, proteins, rna, schlemm's canal, biosynthesis, quantitative real-time polymerase chain reaction, fluid flow
Invest. Ophthalmol. Vis. Sci.. 2011; 52(8):5049-5057. doi: 10.1167/iovs.10-6948

ARVO Annual Meeting Abstract April 2011

Correlations between Tear IP-10 and other Biomarkers in Normal and Dry Eye Patients

Tammy P. Than; Nicole Guyette; Karin Tran; Keshia Elder; Janene Sims; Lucy Kehinde; Pearl Shin; Larezia Williams; John Bradley; Roderick Fullard

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):3807. doi:

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Substrate stiffness triggers an extracellular matrix response in human trabecular meshwork cells and tissues

Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells

The role of Myosin-X in tunneling nanotube formation by trabecular meshwork cells

Novel extracellular protein kinases Fam20A and Fam20C differentially distribute with MMP14 at PILS in TM cells

Unidirectional transfer of cellular cargo between trabecular meshwork cells via novel actin-based filopodia

Matrix metalloproteinase-14 dimerization orchestrates matrix degradation at podosome- or invadopodia-like structures (PILS) in trabecular meshwork.

Conjunctival gene expression differences between aqueous-deficient and evaporative dry eye patients relative to controls

Differential Effects of Caveolin-1 and -2 Knockdown on Aqueous Outflow and Altered Extracellular Matrix Turnover in Caveolin-Silenced Trabecular Meshwork Cells

Correlations between non-stimulated tear levels and conjunctival gene expression of MAPK pathway-associated biomarkers in aqueous-deficient dry eye and control patients

Caveolins modulate ECM turnover by Trabecular Meshwork cells

Correlations between non-stimulated tear levels and conjunctival surface expression of inflammation-related biomarkers in normal and aqueous-deficient dry eye patients

Comparison of Low-Abundance Biomarker Levels in Capillary-Collected Nonstimulated Tears and Washout Tears of Aqueous-Deficient and Normal Patients

Perturbation of Hyaluronan Synthesis in the Trabecular Meshwork and the Effects on Outflow Facility

Conjunctival Gene Expression Patterns in Dry Eye; Real Time PCR and Beyond

Non-stimulated Tear Levels and Conjunctival Expression of IL-8 and IP-10 in Normal and Dry Eye Patients

Dynasore - A Dynamin Inhibitor Alters Outflow Facility and Endosomal Uptake in Trabecular Meshwork Cells

Gleevec Alters Endosomal Arrangement at PILS and Inhibits Extracellular Matrix (ECM) Degradation in Trabecular Meshwork Cells

Molecular Chaperone Function for Myocilin

Segmental Versican Expression in the Trabecular Meshwork and Involvement in Outflow Facility

Correlations between Tear IP-10 and other Biomarkers in Normal and Dry Eye Patients

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