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ARVO Annual Meeting Abstract June 2020

AAV capsid variants target canine and primate bipolar cells after subretinal and intravitreal delivery

William A Beltran; Natalia Dolgova; Valerie L Dufour; Iwabe Simone; Ryan F. Boyd; Joshua T Bartoe; Gustavo D Aguirre; David L schaffer; John Gerard Flannery; Leah Byrne

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4489. doi:

ARVO Annual Meeting Abstract June 2020

scAAV.7m8 and VMD2 Promoter as Novel Gene Delivery Tools Targeting Chicken RPE

Yan Zhang; Mei Li; Alexander Ly; John Gerard Flannery; Christine Wildsoet

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):855. doi:

ARVO Annual Meeting Abstract June 2020

AAV gene therapy restores ON-bipolar cell function in a canine model of LRIT3 -congenital stationary night blindness

Keiko Miyadera; Karolina Roszak; Ana Ripolles Garcia; Evelyn Santana; Sommer M Iffrig; Meike Visel; Leah Byrne; William A Beltran; John Gerard Flannery; Gustavo D Aguirre

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2298. doi:

ARVO Annual Meeting Abstract July 2019

A modular linked-AAV building block system for gene and protein delivery

Bilge Esin Ozturk; Timothy P Day; Serhan Turunc; Sara Jabalameli; John Gerard Flannery; Jose Alain Sahel; Leah Byrne

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2901. doi:

ARVO Annual Meeting Abstract July 2019

AAV-mediated Targeting of Müller Glia in Healthy and Diseased Retina

Cecile Fortuny; Cameron Baker; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2907. doi:

ARVO Annual Meeting Abstract July 2019

Restoration of high-sensitivity and adapting vision with a cone opsin

Michael Berry; Amy Holt; Joshua Levitz; Autoosa Salari; John Gerard Flannery; Ehud Isacoff

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5198. doi:

ARVO Annual Meeting Abstract July 2018

AAV mediated delivery of NT4 specifically to Müller glial cells promotes retinal ganglion cell survival in the DBA/2J mouse model of glaucoma.

Anna M Demetriades; Chendong Pan; Leah Byrne; Jeffrey Harder; Simon W John; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):6135. doi:

ARVO Annual Meeting Abstract September 2016

ChR2 Stimulation in Müller cells Modulates the Retinal Light Response

Cameron Baker; Janette Tang; Mike Berry; Ehud Isacoff; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4194. doi:

ARVO Annual Meeting Abstract September 2016

AAV-mediated MANF (mesencephalic astrocyte-derived neurotrophic factor) expression protects retinal ganglion cells in a retinal ischemia/reperfusion mouse model

Yanming Huang; Zhenya Gao; Galina Dvoriantchikova; Dmitry V Ivanov; Yuan Kang; John Gerard Flannery; Rong Wen; Yiwen Li

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4411. doi:

ARVO Annual Meeting Abstract September 2016

Directed evolution identifies novel AAV capsid variants for targeting the canine outer retina following intravitreal delivery

Leah C Byrne; Meike Visel; Valerie Dufour; Felipe Pompeo Marinho; Gustavo D Aguirre; William A Beltran; David Schaffer; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):776. doi:

ARVO Annual Meeting Abstract September 2016

Evaluation of CRB1 gene delivery in the rd8 mouse

Timothy P Day; Cecile Fortuny; Yebon Oh; David Schaffer; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):1183. doi:

ARVO Annual Meeting Abstract September 2016

Retinal Cells Generate and Secrete Cytokines and Bioreactive Lipids that Promote Choriocapillaris Homeostasis

Peter D Westenskow; Salome Murinello; Daniel Feitelberg; Edith Aguilar; Leah C Byrne; John Gerard Flannery; Gary Siuzdak; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract September 2016

Müller glial cell-specific GDNF expression promotes retinal ganglion cell survival in DBA/2J mice

Anna M Demetriades; Chendong Pan; Leah C Byrne; Erum Ahmed; Jeffrey Harder; Simon W John; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

ARVO Annual Meeting Abstract June 2015

Characterization of CRB1 gene therapy in a retinal degeneration mouse model

Timothy P Day; Trevor Lee; Jan Wijnholds; David Schaffer; John Gerard Flannery

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3633. doi:

ARVO Annual Meeting Abstract June 2015

Neuroprotective effect of AAV-mediated cell-specific expression of GDNF in Müller glial cells versus retinal ganglion cells in a murine model of glaucoma

Chendong Pan; Noreen Shaikh; Steven Gu; Leah Byrne; Meike Visel; Thomas Walter Chalberg; David Schaffer; John Gerard Flannery; Anna M Demetriades

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2421. doi:

ARVO Annual Meeting Abstract June 2015

CRALBP is required for the function of the mammalian retina visual cycle and normal M-cone vision

Yunlu Xue; Susan Shen; Jonathan Jui; Alan C Rupp; Leah Byrne; Samer Hattar; John Gerard Flannery; Joseph C Corbo; Vladimir J Kefalov

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):1703. doi:

ARVO Annual Meeting Abstract June 2015

Gene Therapy into Photoreceptors and Müller Glial Cells Restores Retinal Structure and Function in Crb1 Retinitis Pigmentosa Mouse Models

Jan Wijnholds; C. Henrique F. Alves; Peter Quinn; Rogier Vos; Jan Klooster; John Gerard Flannery; J. Alexander Heimel; Lucie P Pellissier

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2067. doi:

ARVO Annual Meeting Abstract April 2014

AAV-mediated gene therapy in Dystrophin-Dp71 deficient mouse leads to blood-retinal barrier permeability restoration

Ophelie Vacca; Brahim El Mathari; Marie Darche; Peggy Barbe; David V Schaffer; John Gerard Flannery; Jose Alain Sahel; Ramin Tadayoni; Deniz Dalkara; Alvaro Rendon

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):833. doi:

ARVO Annual Meeting Abstract April 2014

Cone Photoreceptors Can Generate the Potent Neurotrophic and Pro-angiogenic Fatty Acid Amide Erucamide

Peter D Westenskow; Toshihide Kurihara; Yoshihiko Usui; Stephen Bravo; Junhua Wang; Leah C Byrne; Yoshihiro Wakabayashi; John Gerard Flannery; Gary Suizdak; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):5753. doi:

ARVO Annual Meeting Abstract April 2014

Angiogenin is a potent modulator of neovascularization and inflammation that is upregulated in various human retinal diseases

Carli M Wittgrove; Liliana P Paris; Yoshihiko Usui; Yoshihiro Wakabayashi; Edith Aguilar; Daniel Feitelberg; Peter D Westenskow; Leah C Byrne; John Gerard Flannery; Martin Friedlander

Invest. Ophthalmol. Vis. Sci.. 2014; 55(13):2242. doi:

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