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ARVO Annual Meeting Abstract June 2021

A two-step model of PVL and ROP

Weilin Song; George Hoppe; Demiana Hanna; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):3001. doi:

ARVO Annual Meeting Abstract June 2020

Foveal capillary perfusion density decreases in diabetics with DME treated on a fixed regimen of intravitreal aflibercept injections over 24 months

Brittney Statler; Thais Conti; Felipe Ferreira Conti; Fabiana Q Silva; Aleksandra Rachitskaya; Alex Yuan; Andrew Schachat; Justis P Ehlers; Jonathan E Sears; Sunil K Srivastava; Rishi P Singh; Amy Babiuch

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4360. doi:

ARVO Annual Meeting Abstract June 2020

Presentation and outcomes of patients with post-injection endophthalmitis at a large academic center

Michael Ramos; Srinidhi Singuri; Lucy Xu; Julio Castillo; Justis P Ehlers; Peter M Kaiser; Rishi P Singh; Aleksandra Rachitskaya; Sunil K Srivastava; Jonathan E Sears; Andrew Schachat; Amy Babiuch; Sumit Sharma; Daniel F Martin; Careen Y Lowder; Alex Yuan

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4410. doi:

ARVO Annual Meeting Abstract June 2020

Retinal metabolic remodeling and hepatic nitrogen imbalance in oxygen induced retinopathy (OIR)

Charandeep Singh; Andrew Benos; Vincent Tran; Leah McCollum; Youstina Bolok; Hanna Demiana; Kristin Allan; Alex Yuan; George Hoppe; Henri Brunengraber; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):5405. doi:

ARVO Annual Meeting Abstract July 2019

Novel mutation in CTNNB1 causing familial exudative vitreoretinopathy and microcephaly

Razek Georges Coussa; Yue Zhao; Meghan J DeBenedictis; Allison Babiuch; Jonathan E Sears; Elias I Traboulsi

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2947. doi:

ARVO Annual Meeting Abstract July 2019

Müller Cell HIF-2 is Not Required for Protection Against Oxygen Induced Retinopathy by Prolyl Hydroxylase Inhibition

George Hoppe; Youstina Bolok; Leah McCollum; Charandeep Singh; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1655. doi:

ARVO Annual Meeting Abstract July 2018

FEVR-like Phenotype of Zone 1 Type 1 Infants Treated with anti-VEGF Therapy

Christine Sonnie; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3769. doi:

ARVO Annual Meeting Abstract July 2018

3-Hydroxypyruvate accumulates in the retina of newborn mice exposed to hyperoxia and may contribute to angiostasis

Amit Sharma; Charandeep Singh; Weilin Song; Youstina Bolok; Jin Zhang; George Hoppe; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5462. doi:

ARVO Annual Meeting Abstract July 2018

Serine metabolism is a key pathway involved in the prevention of oxygen-induced retinopathy by Roxadustat

Charandeep Singh; Amit Sharma; George Hoppe; Henri Brunengraber; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5464. doi:

Retina July 2018

3-Hydroxypyruvate Destabilizes Hypoxia Inducible Factor and Induces Angiostasis

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Charandeep Singh; Amit Sharma; George Hoppe; Weilin Song; Youstina Bolok; Jonathan E. Sears
TAGS: hypoxia, metabolites, pyruvates
Invest. Ophthalmol. Vis. Sci.. 2018; 59(8):3440-3448. doi: https://doi.org/10.1167/iovs.18-24120

ARVO Annual Meeting Abstract June 2017

Efficacy of novel hypoxia inducible factor-prolyl hydroxylase (HIF-PH) inhibitor in the prevention of retinopathy of prematurity (ROP)

Jin Zhang; George Hoppe; John Wang; Youstina Bolok; Amit Sharma; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3465. doi:

ARVO Annual Meeting Abstract June 2017

Long-term clinical outcomes of pars plana (PP) versus anterior chamber (AC) placement of glaucoma tube implants

Vivian Qin; Mona A Kaleem; Edward J Rockwood; Annapurna Singh; Shalini Sood-Mendiratta; Jonathan E Sears; Swathi Trace; Fabiana Queiroga de Paula Araujo Silva; Jonathan Eisengart; Rishi P Singh

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):4961. doi:

ARVO Annual Meeting Abstract June 2017

Assessment of pre-trial bevacizumab response in the REACT study: A prospective comparative dosing trial of ranibizumab in eyes previously treated with bevacizumab.

sruthi arepalli; Sunil K Srivastava; Rishi P Singh; Alex Yuan; Jonathan E Sears; Jamie Reese; Stiegel Laura; Justis Ehlers

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1913. doi:

ARVO Annual Meeting Abstract June 2017

Development of geographic atrophy in age-related macular degeneration treated with long term intravitreal injections of anti-vascular endothelial growth factor.

Ang Li; Fabiana Queiroga de Paula Araujo Silva; Jonathan E Sears; Sunil K Srivastava; Justis Ehlers; Andrew Schachat; Peter K Kaiser; Daniel F Martin; Rishi P Singh

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):897. doi:

ARVO Annual Meeting Abstract June 2017

Comparison of efficacy and safety of intravitreal triamcinolone acetonide vs dexamethasone implant (Ozurdex) in treatment of diabetic macular edema

Rachel C Chen; Justis Ehlers; Rishi P Singh; Sunil K Srivastava; Daniel F Martin; Andrew Schachat; Jonathan E Sears; Alex Yuan; Amy Shrader Babiuch; Peter K Kaiser

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):921. doi:

ARVO Annual Meeting Abstract September 2016

Comparative Systems Pharmacology of HIF Stabilization in the Prevention of Retinopathy of Prematurity

George Hoppe; Suzy Yoon; Banu Gopalan; Rebecca Brown; Kelsey Case; Amit Vasanji; Ernest Ricky Chan; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):3631. doi:

ARVO Annual Meeting Abstract September 2016

Incidence of ROP After SUPPORT

Jonathan E Sears; Christine Sonnie; George Hoppe

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):6287. doi:

ARVO Annual Meeting Abstract June 2015

IFIT3/P60 Expression Reflects Cell Specific Response to Viral Infection

Nathaniel Sears; Steffen Christoffersen; George Hoppe; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):838. doi:

ARVO Annual Meeting Abstract June 2015

Pharmacological Stabilization of Hypoxia Inducible Factor 1 by FG 4592 Prevents Oxygen Induced Retinopathy

Jonathan E Sears; Suzy Yoon; Rebecca Brown; Kelsey Case; George Hoppe; Retina Cell Biology

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3634. doi:

ARVO Annual Meeting Abstract June 2015

HIF stabilization in the liver prevents ROP by secreting hepatokines capable of promoting metabolic switch in retinal endothelium

George Hoppe; Suzy Yoon; Banu Gopalan; Rebecca Brown; Kelsey Case; Richard E Morton; Jonathan E Sears

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):3643. doi:

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A two-step model of PVL and ROP

Foveal capillary perfusion density decreases in diabetics with DME treated on a fixed regimen of intravitreal aflibercept injections over 24 months

Presentation and outcomes of patients with post-injection endophthalmitis at a large academic center

Retinal metabolic remodeling and hepatic nitrogen imbalance in oxygen induced retinopathy (OIR)

Novel mutation in CTNNB1 causing familial exudative vitreoretinopathy and microcephaly

Müller Cell HIF-2 is Not Required for Protection Against Oxygen Induced Retinopathy by Prolyl Hydroxylase Inhibition

FEVR-like Phenotype of Zone 1 Type 1 Infants Treated with anti-VEGF Therapy

3-Hydroxypyruvate accumulates in the retina of newborn mice exposed to hyperoxia and may contribute to angiostasis

Serine metabolism is a key pathway involved in the prevention of oxygen-induced retinopathy by Roxadustat

3-Hydroxypyruvate Destabilizes Hypoxia Inducible Factor and Induces Angiostasis

Efficacy of novel hypoxia inducible factor-prolyl hydroxylase (HIF-PH) inhibitor in the prevention of retinopathy of prematurity (ROP)

Long-term clinical outcomes of pars plana (PP) versus anterior chamber (AC) placement of glaucoma tube implants

Assessment of pre-trial bevacizumab response in the REACT study: A prospective comparative dosing trial of ranibizumab in eyes previously treated with bevacizumab.

Development of geographic atrophy in age-related macular degeneration treated with long term intravitreal injections of anti-vascular endothelial growth factor.

Comparison of efficacy and safety of intravitreal triamcinolone acetonide vs dexamethasone implant (Ozurdex) in treatment of diabetic macular edema

Comparative Systems Pharmacology of HIF Stabilization in the Prevention of Retinopathy of Prematurity

Incidence of ROP After SUPPORT

IFIT3/P60 Expression Reflects Cell Specific Response to Viral Infection

Pharmacological Stabilization of Hypoxia Inducible Factor 1 by FG 4592 Prevents Oxygen Induced Retinopathy

HIF stabilization in the liver prevents ROP by secreting hepatokines capable of promoting metabolic switch in retinal endothelium

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