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Genetics July 2020

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

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Milica A. Margeta; Sophia M. Letcher; Robert P. Igo, Jr.; Jessica N. Cooke Bailey; Louis R. Pasquale; Jonathan L. Haines; Oleg Butovsky; Janey L. Wiggs; for the NEIGHBORHOOD consortium
TAGS: apolipoprotein e, glaucoma, open-angle glaucoma, trem2 gene, alleles
Invest. Ophthalmol. Vis. Sci.. 2020; 61(8):3. doi: https://doi.org/10.1167/iovs.61.8.3

ARVO Annual Meeting Abstract June 2020

Statistical driver genes and the missing heritability of age-related macular degeneration

Andrea R Waksmunski; Michelle Grunin; Tyler G Kinzy; Robert Igo; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1895. doi:

ARVO Annual Meeting Abstract June 2020

A Genome-wide Association Study of Drusen Traits in the Amish

Michael David Osterman; Yeunjoo E Song; Muneeswar G. Nittala; Srinivas Sadda; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2440. doi:

ARVO Annual Meeting Abstract June 2020

Dense SNP IAMDGC Dataset Developed through Imputation

Michelle Grunin; Karen Y He; Robert Igo; Yeunjoo E Song; Mathias Gorski; Iris M Heid; Xiaofeng Zhu; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):3517. doi:

ARVO Annual Meeting Abstract June 2020

Analysis of ATXN2 trinucleotide repeats in primary open angle glaucoma patients

Shi Song Rong; Robert Igo; Jessica Cooke Bailey; Jonathan L Haines; Louis Pasquale; Janey Wiggs

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1247. doi:

ARVO Annual Meeting Abstract June 2020

Glaucoma Examination in the Amish of Holmes County, Ohio

Jonathan Mikal Skarie; Tyler G Kinzy; Jane Sewell; Yeunjoo E Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Sherri Hochstetler; Louis R Pasquale; Janey Wiggs; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1252. doi:

ARVO Annual Meeting Abstract June 2020

Genetic Correlation between Corneal Hysteresis and Vertical Cup-disc Ratio in South Indian Consanguineous Pedigrees

Baojian Fan; P Ferdina Marie Sharmila; N Soumittra; Sripriya Sarangapani; Xiaoyi Gao; David S Friedman; L Vijaya; Jonathan L Haines; Ronnie J George; Janey Wiggs

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1253. doi:

ARVO Annual Meeting Abstract June 2020

Retinal pigment epithelium (RPE) pigmentary changes are associated with progression from early to advanced age-related macular degeneration (AMD) independent of CFH and ARMS2 risk genotypes.

William K Scott; Susan H. Slifer; Jacob K. Welch; Stephen G Schwartz; Jaclyn L Kovach; Srinivas Sadda; Muneeswar G. Nittala; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):4189. doi:

Genetics September 2019

Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

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Andrea R. Waksmunski; Michelle Grunin; Tyler G. Kinzy; Robert P. Igo, Jr; Jonathan L. Haines; Jessica N. Cooke Bailey; for the International Age-Related Macular Degeneration Genomics Consortium
TAGS: age-related macular degeneration, candidate disease gene, genes, genome, genome-wide association study, ophthalmology, universities, schools, medical, proteins, genetics
Invest. Ophthalmol. Vis. Sci.. 2019; 60(12):4041-4051. doi: https://doi.org/10.1167/iovs.19-27827

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2019

Pathway analysis identifies PLCG2 as a candidate gene for age-related macular degeneration

Andrea R Waksmunski; Michelle Grunin; Tyler Kinzy; Robert P. Igo; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2959. doi:

ARVO Annual Meeting Abstract July 2019

Three loci associated with risk of advanced age-related macular degeneration (AMD) also influence anti-VEGF treatment response

William K Scott; Omar García Rodríguez; Patrice Whitehead-Gay; Larry D. Adams; Jacob K. Welch; Renee Laux; Milam A Brantley; Jaclyn L. Kovach; Stephen G Schwartz; Anita Agarwal; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2968. doi:

ARVO Annual Meeting Abstract July 2019

Metabolomics reveals changes in fatty acid metabolism in age-related macular degeneration patients

Milam A Brantley; Karan Uppal; Chunyu Ma; Anita Agarwal; Margaret A Pericak-Vance; William K Scott; Jonathan L Haines; Dean Jones; Sabrina L Mitchell

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1187. doi:

ARVO Annual Meeting Abstract July 2019

Glaucoma Examination in the Amish of Holmes County, Ohio

Jonathan Mikal Skarie; Tyler Kinzy; Jane Sewell; Yeunjoo E. Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Erika Trapl; Farren BS Briggs; Louis R Pasquale; Janey L Wiggs; Jonathan L Haines; Jessica Cooke Bailey

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1602. doi:

ARVO Annual Meeting Abstract July 2019

Family-based Genome-wide Association Study in South Indian Consanguineous Pedigrees Identifies an Association between LPHN3 and Vertical Cup-disc Ratio

Baojian Fan; P Ferdina Marie Sharmila; N Soumittra; S Sripriya; X. Raymond Gao; David S Friedman; L Vijaya; Jonathan L Haines; Ronnie J George; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1618. doi:

ARVO Annual Meeting Abstract July 2019

Association of APOE with POAG suggests a protective effect for APOE4

Sophia M Letcher; Milica Margeta; Robert P. Igo; Jessica Cooke Bailey; Jonathan L Haines; Oleg Butovsky; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1627. doi:

ARVO Annual Meeting Abstract July 2019

Genome-wide Association Study of Choroidal Thickness in the Amish

Omar García Rodríguez; Susan Hackleman Slifer; William K Scott; Yeunjoo E. Song; Kristy Miskimen; Muneeswar Gupta Nittala; Srinivas R Sadda; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):2831. doi:

Retina October 2018

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

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Sabrina L. Mitchell; Karan Uppal; Samantha M. Williamson; Ken Liu; L. Goodwin Burgess; ViLinh Tran; Allison C. Umfress; Kelli L. Jarrell; Jessica N. Cooke Bailey; Anita Agarwal; Margaret Pericak-Vance; Jonathan L. Haines; William K. Scott; Dean P. Jones; Milam A. Brantley, Jr
TAGS: carnitine, exudative age-related macular degeneration, metabolites, metabolomics, plasma
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4978-4985. doi: https://doi.org/10.1167/iovs.18-25137

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Genetic, metagenomic, host response, and environmental factors influences on corneal infiltrative events in soft contact lens wearers: the MERGE pilot study

Kathryn Richdale; Cecilia Chao; Lakshmi Akileswaran; Russell Van Gelder; Jessica Cooke Bailey; Jonathan L Haines; Fiona Stapleton; Carol Lakkis; Mark D P Willcox

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1743. doi:

ARVO Annual Meeting Abstract July 2018

Glaucoma Examination in the Amish of Holmes County, Ohio

Jessica Cooke Bailey; Yeunjoo E Song; Jonathan Mikal Skarie; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Louis R. Pasquale; Janey L Wiggs; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1818. doi:

ARVO Annual Meeting Abstract July 2018

Choroidal Vascularity Index in Geographic Atrophy secondary to dry Age Related Macular Degeneration

Jyotsna Maram; Muneeswar Gupta Nittala; Siva Balasubramanian; Swetha Bindu Velaga; Jay Chhablani; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3208. doi:

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Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4

Statistical driver genes and the missing heritability of age-related macular degeneration

A Genome-wide Association Study of Drusen Traits in the Amish

Dense SNP IAMDGC Dataset Developed through Imputation

Analysis of ATXN2 trinucleotide repeats in primary open angle glaucoma patients

Glaucoma Examination in the Amish of Holmes County, Ohio

Genetic Correlation between Corneal Hysteresis and Vertical Cup-disc Ratio in South Indian Consanguineous Pedigrees

Retinal pigment epithelium (RPE) pigmentary changes are associated with progression from early to advanced age-related macular degeneration (AMD) independent of CFH and ARMS2 risk genotypes.

Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

Pathway analysis identifies PLCG2 as a candidate gene for age-related macular degeneration

Three loci associated with risk of advanced age-related macular degeneration (AMD) also influence anti-VEGF treatment response

Metabolomics reveals changes in fatty acid metabolism in age-related macular degeneration patients

Glaucoma Examination in the Amish of Holmes County, Ohio

Family-based Genome-wide Association Study in South Indian Consanguineous Pedigrees Identifies an Association between LPHN3 and Vertical Cup-disc Ratio

Association of APOE with POAG suggests a protective effect for APOE4

Genome-wide Association Study of Choroidal Thickness in the Amish

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

Genetic, metagenomic, host response, and environmental factors influences on corneal infiltrative events in soft contact lens wearers: the MERGE pilot study

Glaucoma Examination in the Amish of Holmes County, Ohio

Choroidal Vascularity Index in Geographic Atrophy secondary to dry Age Related Macular Degeneration

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