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Retina October 2018

The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

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Sabrina L. Mitchell; Karan Uppal; Samantha M. Williamson; Ken Liu; L. Goodwin Burgess; ViLinh Tran; Allison C. Umfress; Kelli L. Jarrell; Jessica N. Cooke Bailey; Anita Agarwal; Margaret Pericak-Vance; Jonathan L. Haines; William K. Scott; Dean P. Jones; Milam A. Brantley, Jr
TAGS: carnitine, plasma, exudative age-related macular degeneration, metabolites, metabolomics
Invest. Ophthalmol. Vis. Sci.. 2018; 59(12):4978-4985. doi: 10.1167/iovs.18-25137

Includes: Supplemental Content

ARVO Annual Meeting Abstract July 2018

Investigation of a rare risk variant in complement factor H for age-related macular degeneration in the Amish

Andrea R. Waksmunski; Kristy Miskimen; Yeunjoo E. Song; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Larry D. Adams; Laura Caywood; Michael Prough; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1420. doi:

ARVO Annual Meeting Abstract July 2018

Genetic, metagenomic, host response, and environmental factors influences on corneal infiltrative events in soft contact lens wearers: the MERGE pilot study

Kathryn Richdale; Cecilia Chao; Lakshmi Akileswaran; Russell Van Gelder; Jessica Cooke Bailey; Jonathan L Haines; Fiona Stapleton; Carol Lakkis; Mark D P Willcox

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1743. doi:

ARVO Annual Meeting Abstract July 2018

Glaucoma Examination in the Amish of Holmes County, Ohio

Jessica Cooke Bailey; Yeunjoo E Song; Jonathan Mikal Skarie; Renee Laux; Denise Fuzzell; Sarada Fuzzell; Louis R. Pasquale; Janey L Wiggs; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):1818. doi:

ARVO Annual Meeting Abstract July 2018

Choroidal Vascularity Index in Geographic Atrophy secondary to dry Age Related Macular Degeneration

Jyotsna Maram; Muneeswar Gupta Nittala; Siva Balasubramanian; Swetha Bindu Velaga; Jay Chhablani; Jonathan L Haines; Margaret A Pericak-Vance; Dwight Stambolian; Srinivas R. Sadda

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):3208. doi:

ARVO Annual Meeting Abstract July 2018

Ocular phenome-wide association study (PheWAS) of glaucoma-associated genes identifies significant associations with ocular quantitative traits

Baojian Fan; Vimal Konduri; P Ferdina Marie Sharmila; N. Soumittra; S. Sripriya; David S Friedman; L. Vijaya; Jonathan L Haines; Ronnie J. George; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5135. doi:

ARVO Annual Meeting Abstract July 2018

Shared genetic effects between diabetes-related traits and glaucoma-related traits

Louis R. Pasquale; Vincent Laville; Hugo Aschard; Adriana I Iglesias; Jae H Kang; David Mackey; Veronique Vitart; Cornelia van Duijn; Jonathan L Haines; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2018; 59(9):5144. doi:

Genetics May 2018

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

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Bao Jian Fan; Xueli Chen; Nisha Sondhi; P. Ferdinamarie Sharmila; Nagasamy Soumittra; Sarangapani Sripriya; Srinivasan Sacikala; Rashima Asokan; David S. Friedman; Louis R. Pasquale; X. Raymond Gao; Lingam Vijaya; Jessica Cooke Bailey; Veronique Vitart; Stuart MacGregor; Christopher J. Hammond; Chiea Chuen Khor; Jonathan L. Haines; Ronnie George; Janey L. Wiggs; for the Mexican American Glaucoma Genetic Study; International Glaucoma Genetics Consortium; and NEIGHBORHOOD Consortium
TAGS: cohort studies, family, genetic pedigree, single nucleotide polymorphism, cornea, genome-wide association study
Invest. Ophthalmol. Vis. Sci.. 2018; 59(6):2495-2502. doi: 10.1167/iovs.17-23536

Includes: Supplemental Content

Glaucoma February 2018

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

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Jessica N. Cooke Bailey; Puya Gharahkhani; Jae H. Kang; Mariusz Butkiewicz; David A. Sullivan; Robert N. Weinreb; Hugues Aschard; R. Rand Allingham; Allison Ashley-Koch; Richard K. Lee; Sayoko E. Moroi; Murray H. Brilliant; Gadi Wollstein; Joel S. Schuman; John H. Fingert; Donald L. Budenz; Tony Realini; Terry Gaasterland; William K. Scott; Kuldev Singh; Arthur J. Sit; Robert P. Igo, Jr; Yeunjoo E. Song; Lisa Hark; Robert Ritch; Douglas J. Rhee; Douglas Vollrath; Donald J. Zack; Felipe Medeiros; Thasarat S. Vajaranant; Daniel I. Chasman; William G. Christen; Margaret A. Pericak-Vance; Yutao Liu; Peter Kraft; Julia E. Richards; Bernard A. Rosner; Michael A. Hauser; Jamie E. Craig; Kathryn P. Burdon; Alex W. Hewitt; David A. Mackey; Jonathan L. Haines; Stuart MacGregor; Janey L. Wiggs; Louis R. Pasquale; for the Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium
TAGS: testosterone, metabolism, polymorphism, glaucoma, genes, open-angle glaucoma, datasets
Invest. Ophthalmol. Vis. Sci.. 2018; 59(2):629-636. doi: 10.1167/iovs.17-22708

Includes: Supplemental Content

Genetics August 2017

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

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Patrice J. Persad; Iris M. Heid; Daniel E. Weeks; Paul N. Baird; Eiko K. de Jong; Jonathan L. Haines; Margaret A. Pericak-Vance; William K. Scott; for the International Age-Related Macular Degeneration Genomics Consortium (IAMDGC)
TAGS: mitochondria, chromosomes, human, pair 15, genome, single nucleotide polymorphism, genetics, age-related macular degeneration, significance, datasets
Invest. Ophthalmol. Vis. Sci.. 2017; 58(10):4027-4038. doi: 10.1167/iovs.17-21734

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2017

Contribution of AMD risk variants to the genetic architecture of choroidal thickness in the Amish

Nicole Restrepo; Yeunjoo Song; Renee Laux; Larry Deon Adams; Denise Fuzzell; Laura J Caywood; Violet Horst; Tine MacKay; Debbie Dana; Muneeswar Gupta Nittala; Srinivas R Sadda; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1835. doi:

ARVO Annual Meeting Abstract June 2017

New evidence for enrichment of metabolic, signaling, and inflammatory pathways in age-related macular degeneration

Andrea R Waksmunski; Jessica Cooke Bailey; Margaret A Pericak-Vance; William K Scott; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):1851. doi:

ARVO Annual Meeting Abstract June 2017

Genetic Variation in RRAGC Affects Progression Rate from Intermediate to Advanced Age-Related Macular Degeneration

William K Scott; Patrice Persad; Rebecca J Sardell; Samuel S Pan; Patrice Whitehead Gay; Larry Deon Adams; Renee Laux; Jorge Fortun; Milam A Brantley; Jaclyn L Kovach; Stephen G Schwartz; Anita Agarwal; Jonathan L Haines; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3424. doi:

ARVO Annual Meeting Abstract June 2017

Association of ANGPT1 with Primary Open Angle Glaucoma

Jessica Cooke Bailey; Puya Gharahkhani; Stuart W Tompson; Tomokazu Souma; Owen Siggs; Terri L Young; Angelo P Tanna; Louis R Pasquale; Susan E Quaggin; Stuart MacGregor; Jamie E Craig; Jonathan L Haines; Janey L. Wiggs

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):3822. doi:

ARVO Annual Meeting Abstract June 2017

The Amish Eye Study: Baseline Quantitative Ocular Characteristics on a Unique Cohort

Jonathan L Haines; Nicole Restrepo; Yeunjoo Song; Renee Laux; Larry Deon Adams; Denise Fuzzell; Laura J Caywood; Violet Horst; Tine MacKay; Debbie Dana; Muneeswar Gupta Nittala; Srinivas R Sadda; William K Scott; Dwight Stambolian; Margaret A Pericak-Vance

Invest. Ophthalmol. Vis. Sci.. 2017; 58(8):188. doi:

Genetics November 2016

Progression Rate From Intermediate to Advanced Age-Related Macular Degeneration Is Correlated With the Number of Risk Alleles at the CFH Locus

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Rebecca J. Sardell; Patrice J. Persad; Samuel S. Pan; Patrice Whitehead; Larry D. Adams; Reneé A. Laux; Jorge A. Fortun; Milam A. Brantley, Jr; Jaclyn L. Kovach; Stephen G. Schwartz; Anita Agarwal; Jonathan L. Haines; William K. Scott; Margaret A. Pericak-Vance
TAGS: alleles, choroidal neovascularization, genotype, single nucleotide polymorphism, eye, age-related macular degeneration, genetic risk
Invest. Ophthalmol. Vis. Sci.. 2016; 57(14):6107-6115. doi: 10.1167/iovs.16-19519

Includes: Supplemental Content

ARVO Annual Meeting Abstract September 2016

Testosterone pathway polymorphisms in relation to primary open angle glaucoma: an analysis stratified by sex

Louis R Pasquale; Jessica Cooke Bailey; Jae H Kang; Hugo Aschard; Michael A Hauser; R Rand Allingham; David A Sullivan; Jonathan L Haines; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):815. doi:

ARVO Annual Meeting Abstract September 2016

The heritability of choroidal thickness in the Amish

Margaret A Pericak-Vance; Rebecca J Sardell; Muneeswar gupta Nittala; Larry Deon Adams; Renee Laux; Debra Dana; William K Scott; Srinivas R Sadda; Dwight Stambolian; Jonathan L Haines

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):2644. doi:

ARVO Annual Meeting Abstract September 2016

Phenome-wide association study (PheWAS) using glaucoma-related ocular quantitative traits supports WNT7B association with central corneal thickness

Baojian Fan; P Ferdina Marie Sharmila; N Soumittra; S Sripriya; David S Friedman; L Vijaya; Jonathan L Haines; R George; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12):4831. doi:

ARVO Annual Meeting Abstract September 2016

Association of miR-182 with High Tension Glaucoma

Yutao Liu; Jessica Cooke Bailey; Inas Helwa; W Daniel Stamer; Rachel W Kuchtey; R Rand Allingham; Michael A Hauser; Louis R Pasquale; Jonathan L Haines; Janey L Wiggs

Invest. Ophthalmol. Vis. Sci.. 2016; 57(12) doi:

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The Carnitine Shuttle Pathway is Altered in Patients With Neovascular Age-Related Macular Degeneration

Investigation of a rare risk variant in complement factor H for age-related macular degeneration in the Amish

Genetic, metagenomic, host response, and environmental factors influences on corneal infiltrative events in soft contact lens wearers: the MERGE pilot study

Glaucoma Examination in the Amish of Holmes County, Ohio

Choroidal Vascularity Index in Geographic Atrophy secondary to dry Age Related Macular Degeneration

Ocular phenome-wide association study (PheWAS) of glaucoma-associated genes identifies significant associations with ocular quantitative traits

Shared genetic effects between diabetes-related traits and glaucoma-related traits

Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

Contribution of AMD risk variants to the genetic architecture of choroidal thickness in the Amish

New evidence for enrichment of metabolic, signaling, and inflammatory pathways in age-related macular degeneration

Genetic Variation in RRAGC Affects Progression Rate from Intermediate to Advanced Age-Related Macular Degeneration

Association of ANGPT1 with Primary Open Angle Glaucoma

The Amish Eye Study: Baseline Quantitative Ocular Characteristics on a Unique Cohort

Progression Rate From Intermediate to Advanced Age-Related Macular Degeneration Is Correlated With the Number of Risk Alleles at the CFH Locus

Testosterone pathway polymorphisms in relation to primary open angle glaucoma: an analysis stratified by sex

The heritability of choroidal thickness in the Amish

Phenome-wide association study (PheWAS) using glaucoma-related ocular quantitative traits supports WNT7B association with central corneal thickness

Association of miR-182 with High Tension Glaucoma

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