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Retina April 2025

Radiomics-Based OCT Analysis of Choroid Reveals Biomarkers of Central Serous Chorioretinopathy

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Ryan Chace Williamson; Kiran Kumar Vupparaboina; Sandeep Chandra Bollepalli; Mohammed Nasar Ibrahim; Nicola Valsecchi; Arman Zarnegar; José-Alain Sahel; Jay Chhablani
TAGS: biological markers, central serous chorioretinopathy, choroid, eye, radiomics, face
Trans. Vis. Sci. Tech.. 2025; 14(4):23. https://doi.org/10.1167/tvst.14.4.23

Retina April 2025

PCARE -Associated Retinopathy – Genetics, Clinical Characteristics, and Natural History

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Lorenzo Bianco; Alessio Antropoli; Amine Benadji; Raphaël Atia; Oana Palacci; Christel Condroyer; Aline Antonio; Julien Navarro; Maurizio Battaglia Parodi; José-Alain Sahel; Christina Zeitz; Isabelle Audo
TAGS: genetics, natural history, retinal diseases, visual impairment, follow-up, eye
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):61. https://doi.org/10.1167/iovs.66.4.61

Includes: Supplemental Content

Retina April 2025

Phenotypic and Genotypic Characterization of RP1L1 -Associated Retinopathy

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Alessio Antropoli; Lorenzo Bianco; Xavier Zanlonghi; Amine Benadji; Christel Condroyer; Aline Antonio; Julien Navarro; Claire-Marie Dhaenens; José-Alain Sahel; Christina Zeitz; Isabelle Audo
TAGS: atypical, genotype, phenotype, retinal diseases, retinitis pigmentosa, macular dystrophy
Invest. Ophthalmol. Vis. Sci.. 2025; 66(4):7. https://doi.org/10.1167/iovs.66.4.7

Includes: Supplemental Content

Multidisciplinary Ophthalmic Imaging March 2025

Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy

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Elham Sadeghi; Katherine Du; Oluwaseyi Ajayi; Elli Davis; Nicola Valsecchi; Mohammed Nasar Ibrahim; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: cortical blindness, diabetic retinopathy, eye, cardiovascular imaging
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):50. https://doi.org/10.1167/iovs.66.3.50

Genetics February 2025

Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll

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Kari Branham; Lassana Samarakoon; Isabelle Audo; Allison R. Ayala; Janet K. Cheetham; Stephen P. Daiger; Patty Dhooge; Jacque L. Duncan; Todd A. Durham; Abigail T. Fahim; Rachel M. Huckfeldt; Robert B. Hufnagel; Susanne Kohl; Ramiro S. Maldonado; Michele Melia; Michel Michaelides; Mark E. Pennesi; José-Alain Sahel; Juliana M. Ferraz Sallum; Mandeep S. Singh; Dror Sharon; Kimberly Stepien; Kaylie Jones; Christina Y. Weng; for the Foundation Fighting Blindness Clinical Consortium Investigator Group
TAGS: blindness, genes, genetics, retinal diseases, social survey
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):12. https://doi.org/10.1167/iovs.66.2.12

Includes: Supplemental Content

Retina November 2024

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

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Elham Sadeghi; Nicola Valsecchi; Mohammed Nasar Ibrahim; Katherine Du; Elli Davis; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Jay Chhablani
TAGS: age-related macular degeneration, cardiovascular imaging, cortical blindness, eye
Invest. Ophthalmol. Vis. Sci.. 2024; 65(13):39. https://doi.org/10.1167/iovs.65.13.39

Retina October 2024

Endpoints and Design for Clinical Trials in USH2A -Related Retinal Degeneration: Results and Recommendations From the RUSH2A Natural History Study

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Maureen G. Maguire; David G. Birch; Jacque L. Duncan; Allison R. Ayala; Lauren N. Ayton; Janet K. Cheetham; Peiyao Cheng; Todd A. Durham; Frederick L. Ferris, III; Carel B. Hoyng; Rachel M. Huckfeldt; Glenn J. Jaffe; Christine Kay; Eleonora M. Lad; Bart P. Leroy; Wendi Liang; Lee S. McDaniel; Michele Melia; Michel Michaelides; Mark E. Pennesi; José-Alain Sahel; Lassana Samarakoon; on behalf of the REDI Working Group and the Foundation Fighting Blindness Clinical Consortium Investigator Group
TAGS: cohort studies, eye, natural history, outcome measures, retinal degeneration, sample size, surrogate endpoints, vision, united states food and drug administration, perimetry
Trans. Vis. Sci. Tech.. 2024; 13(10):15. https://doi.org/10.1167/tvst.13.10.15

Includes: Supplemental Content

Retina September 2024

Loss of ON-Pathway Function in Mice Lacking Lrit3 Decreases Recovery From Lens-Induced Myopia

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Baptiste Wilmet; Christelle Michiels; Jingyi Zhang; Jacques Callebert; José Alain Sahel; Serge Picaud; Isabelle Audo; Christina Zeitz
TAGS: lens (device), lens, crystalline, mice, myopia, recovery of function, 3,4-dihydroxyphenylacetic acid
Invest. Ophthalmol. Vis. Sci.. 2024; 65(11):18. https://doi.org/10.1167/iovs.65.11.18

ARVO Annual Meeting Abstract June 2024

Vitreous barrier function and its influence on drug distribution

Anfisa Ayalon; Avigail Beryozkin; Katherine A Davoli; Jiantao Pu; Xiaoyan Zhao; Jose Alain Sahel; Leah Byrne

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3967.

ARVO Annual Meeting Abstract June 2024

Incidence and risk factors of fellow-eyes wet conversion in unilateral neovascular age-related macular degeneration over 15-years follow-up

Elham Sadeghi; Sharat Chandra Vupparaboina; Sandeep Chandra Bollepalli; Kiran Kumar Vupparaboina; Jose Alain Sahel; Andrew W Eller; Jay Chhablani

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2792.

ARVO Annual Meeting Abstract June 2024

Investigation of choroid vessel segmentation in OCT B-scan images using Pix2Pix generative adversarial networks

Mohammed Nasar Ibrahim; Sandeep Chandra Bollepalli; Jose Alain Sahel; Jay Chhablani; Kiran Kumar Vupparaboina

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2414.

ARVO Annual Meeting Abstract June 2024

Lenadogene Nolparvovec Gene Therapy for Leber Hereditary Optic Neuropathy in the Real-Life Setting

Jose Alain Sahel; Catherine Vignal-Clermont; Valerio Carelli; Chiara La Morgia; Mark L. Moster; Robert C Sergott; Sean P. Donahue; Helene Dollfus; Thomas Klopstock; Rabih Hage; Vasily Smirnov; Catherine Cochard; Francis Munier; Pauline Zoppe; Magali Taiel; Patrick Yu-Wai-Man

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):419.

ARVO Annual Meeting Abstract June 2024

Treatment Options For Acute/Subacute Patients With m.11778G>A MT-ND4 Leber Hereditary Optic Neuropathy: A Meta-Analysis

Patrick Yu-Wai-Man; Nancy J. Newman; Valerio Carelli; Valerie Biousse; Catherine Vignal-Clermont; François Montestruc; Magali Taiel; Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):416.

ARVO Annual Meeting Abstract June 2024

Targeting mitochondrial genetic defects by gene therapy: lessons learned from LHON trials

Jose Alain Sahel

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):11.

ARVO Annual Meeting Abstract June 2024

Radiomics features from optical coherence tomography of choroid differ in healthy and central serous chorioretinopathy patients

Ryan Williamson; Kiran Kumar Vupparaboina; Sandeep Chandra Bollepalli; Mohammed Nasar Ibrahim; Arman Zarnegar; Jose Alain Sahel; Jay Chhablani

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1377.

ARVO Annual Meeting Abstract June 2024

Vision parameters associated with worse balance in retinitis pigmentosa

Rakie Cham; Marion Losdat; Mark S Redfern; Galen Holland; Caroline de Montleau; Cécilia Coen; Isabelle S Audo; Jose Alain Sahel; Colas Nils Authié

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2574.

ARVO Annual Meeting Abstract June 2024

A potential therapeutic target for optic nerve regeneration

Mishal Rao; Ziming Luo; Chia-Chun Liu; Michael Nahmou; Bogdan Tanasa; Aman Virmani; Leah Byrne; Jeffrey Louis Goldberg; Jose Alain Sahel; Kun-Che Chang

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2471.

ARVO Annual Meeting Abstract June 2024

Assessing IRD progression over one year: performance-based testing in virtual reality with a visual search task.

Caroline Kurek; Alexis Defer; Caroline de Montleau; Cécilia Coen; Philippe Chaumet-Riffaud; Isabelle S Audo; Jose Alain Sahel; Colas Nils Authié

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3342.

ARVO Annual Meeting Abstract June 2024

Evolution of Markers of Retinal Degeneration after One Year of Prospective Follow-up in Patients with Rod-Cone Dystrophy: The Natural History Study PHENOROD2

Laure Blouin; Daniel C Chung; James A Gow; Alice Le Meur; Anne Celle; Jose Alain Sahel; Joseph N Martel; Isabelle S Audo

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3090.

ARVO Annual Meeting Abstract June 2024

Histopathologic findings after subretinal surgical implantation of the PRIMA neurostimulation system in patients with geographic atrophy

Martina C Herwig-Carl; Karin U Loeffler; Yannick Liermann; Louisa M Bulirsch; Raffael G. Liegl; Jose Alain Sahel; Thomas Ach; Ralf Hornig; Adnan Kilani; Armin Wolf; Frank G Holz

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4981.

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Radiomics-Based OCT Analysis of Choroid Reveals Biomarkers of Central Serous Chorioretinopathy

PCARE -Associated Retinopathy – Genetics, Clinical Characteristics, and Natural History

Phenotypic and Genotypic Characterization of RP1L1 -Associated Retinopathy

Three-Dimensional Choroidal Vessels Assessment in Diabetic Retinopathy

Characterizing the Genetic Basis for Inherited Retinal Disease: Lessons Learned From the Foundation Fighting Blindness Clinical Consortium's Gene Poll

Three-Dimensional Choroidal Vessels Assessment in Age-Related Macular Degeneration

Endpoints and Design for Clinical Trials in USH2A -Related Retinal Degeneration: Results and Recommendations From the RUSH2A Natural History Study

Loss of ON-Pathway Function in Mice Lacking Lrit3 Decreases Recovery From Lens-Induced Myopia

Vitreous barrier function and its influence on drug distribution

Incidence and risk factors of fellow-eyes wet conversion in unilateral neovascular age-related macular degeneration over 15-years follow-up

Investigation of choroid vessel segmentation in OCT B-scan images using Pix2Pix generative adversarial networks

Lenadogene Nolparvovec Gene Therapy for Leber Hereditary Optic Neuropathy in the Real-Life Setting

Treatment Options For Acute/Subacute Patients With m.11778G>A MT-ND4 Leber Hereditary Optic Neuropathy: A Meta-Analysis

Targeting mitochondrial genetic defects by gene therapy: lessons learned from LHON trials

Radiomics features from optical coherence tomography of choroid differ in healthy and central serous chorioretinopathy patients

Vision parameters associated with worse balance in retinitis pigmentosa

A potential therapeutic target for optic nerve regeneration

Assessing IRD progression over one year: performance-based testing in virtual reality with a visual search task.

Evolution of Markers of Retinal Degeneration after One Year of Prospective Follow-up in Patients with Rod-Cone Dystrophy: The Natural History Study PHENOROD2

Histopathologic findings after subretinal surgical implantation of the PRIMA neurostimulation system in patients with geographic atrophy

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