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Meeting Abstract (54)
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Investigative Ophthalmology & Visual Science (77)
Translational Vision Science & Technology (2)

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ARVO Annual Meeting Abstract (54)
Retina (11)
Retinal Cell Biology (10)
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Retina (23)
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retina (17)
mice (13)
iron (11)
photoreceptors (5)
retinal degeneration (5)
age-related macular degeneration (4)
electroretinography (4)
in situ nick-end labeling (4)
iron chelating agents (4)
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Retina January 2025

Systemic Sodium Iodate Injection as a Model for Expanding Geographic Atrophy

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Brandon D. Anderson; Brent A. Bell; Ying Song; Timothy T. Lee; Tan Wang; Joshua L. Dunaief
TAGS: age-related macular degeneration, nonexudative, atrophy, injections, iodates, sodium, mice, diagnostic imaging, retina
Trans. Vis. Sci. Tech.. 2025; 14(1):9. https://doi.org/10.1167/tvst.14.1.9

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Shared RPE transcriptomic changes in response to two oxidants implicated in AMD pathogenesis: cigarette smoke and iron

Rohini M Nair; Elie Mer; Kevin R Zhang; John W Tobias; Venkata R M Chavali; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):741.

ARVO Annual Meeting Abstract June 2024

Tamoxifen protects photoreceptors in the sodium iodate model

Timothy Taemin Lee; Brent Bell; Ying Song; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):825.

ARVO Annual Meeting Abstract June 2024

Dose-optimized sodium iodate model recapitulates geographic atrophy

Brandon Anderson; Brent Bell; Timothy Taemin Lee; Tan Wang; Ying Song; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):4748.

ARVO Annual Meeting Abstract June 2024

RPE-specific GPx4 knockout recapitulates features of AMD, protected by oxidation-resistant deuterated DHA

Alaina Wojciechowski; Ying Song; Brent Bell; Alexa Conomikes; Cecilia Petruconis; Joseph Yano; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6121.

ARVO Annual Meeting Abstract June 2022

Minimal effect of conditional ferroportin KO in the neural retina implicates ferrous iron in retinal iron overload and degeneration

Yingrui Liu; Bailey Baumann; Ying Song; Kevin Zhang; Maura Poli; Samira Littleton; Zbynek Kozmik; Guanfang Su; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):475 – A0012.

ARVO Annual Meeting Abstract June 2022

Characterization of retinal architecture in a systemic HL/EL double knockout mouse model

Rohini M Nair; Ying Song; Brent A Bell; Kevin Zhang; Daniel J Rader; Joshua L Dunaief; Venkata R M Chavali

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):461.

ARVO Annual Meeting Abstract June 2022

Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis

Kevin R Zhang; Bailey Baumann; Ying Song; Jacob Sterling; Samyuktha Guttha; Zbynek Kozmik; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2485 – F0192.

ARVO Annual Meeting Abstract June 2022

Topical and systemic administration of FDA-approved GLP-1R Agonists rescue retinal ganglion cells in hypertensive glaucoma

Emily Lawrence; Michelle Guo; Johnathan Wong; Turner Schwartz; Jie Wu; Jingwen Lu; Jacob Sterling; Joshua L Dunaief; Qi N Cui

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2848 – A0371.

ARVO Annual Meeting Abstract June 2022

Loss of macrophage chemoattractant protein-1 reduces retinal inflammation and neuron death in hypertensive glaucoma

Michelle Guo; Turner D Schwartz; Jacob Sterling; Jie Wu; Ahab Alnemri; Modupe Adetunji; Emily Lawrence; Ahmara G Ross; Joshua L Dunaief; Qi N Cui

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3091.

ARVO Annual Meeting Abstract June 2021

Inflammatory adipose activates nutritional immunity leading to retinal dysfunction

Jacob Sterling; Bailey Baumann; Sierra Foshe; Andrew P Voigt; Samyuktha Guttha; Ahab Alnemri; Sam McCright; Venkata R M Chavali; David Hill; Deborah A Ferrington; Dwight Stambolian; Robert F Mullins; David Merrick; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):265.

ARVO Annual Meeting Abstract June 2021

Distribution and density of retinal myeloid cells following elevated intraocular pressure

Michelle Guo; Jacob Sterling; Modupe O Adetunji; Joshua L Dunaief; Qi N Cui

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2358.

ARVO Annual Meeting Abstract June 2021

Exposure to glucagon-like peptide 1 receptor (GLP1R) agonists is associated with reduced risk for glaucoma

Qi N Cui; Jacob Sterling; Peiying Hua; Joshua L Dunaief; Brian L VanderBeek

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):1013.

ARVO Annual Meeting Abstract June 2021

RPE-specific knockout of REV-ERBα induces age-dependent RPE degeneration in mice

Shuo Huang; Chi-Hsiu Liu; Zhongxiao Wang; Zhongjie Fu; William R. Britton; Alexandra K. Blomfield; Joshua L Dunaief; Jing Chen

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2955.

ARVO Annual Meeting Abstract June 2020

Mutation of the mitochondrial gene cytochrome c oxidase 1 imparts susceptibility to retinal ganglion cell loss in the setting of ocular hypertension

Qi N Cui; Modupe O Adetunji; gongyi ren; Ying Song; Joshua L Dunaief; Douglas C Wallace

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):264.

ARVO Annual Meeting Abstract June 2020

Retinal pigment epithelial cells “bulk up” when they “pump iron”: lipid and endolysosome accumulation with mechanistic connection to macular degeneration

Kevin Zhang; Bailey Baumann; Ahab Alnemri; Ying Song; Venkata R M Chavali; Claire H Mitchell; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):1422.

ARVO Annual Meeting Abstract June 2020

Ferrous but not ferric iron sulfate kills photoreceptors and induces photoreceptor-dependent RPE autofluorescence

Wanting Shu; Bailey Baumann; Ying Song; Yingrui Liu; Xingwei Wu; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):735.

Retinal Cell Biology October 2019

Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice

PDF

Wanting Shu; Bailey H. Baumann; Ying Song; Yingrui Liu; Xingwei Wu; Joshua L. Dunaief
TAGS: injections, iron, mice, retina
Invest. Ophthalmol. Vis. Sci.. 2019; 60(13):4378-4387. https://doi.org/10.1167/iovs.19-28250

ARVO Annual Meeting Abstract July 2019

Mice with RPE-specific CLIC4 deficiency exhibit AMD-like changes in the retina-RPE-choroid complex

Wataru Otsu; Kuo-Shun Hsu; Joshua L Dunaief; Yao Li; Stephen H. Tsang; Jen-Zen Chuang; Ching-Hwa Sung

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1229.

ARVO Annual Meeting Abstract July 2019

Hepatic Lipase C knockout mouse has diminished ERGs and Bruch’s lipid deposits

Venkata Ramana Murthy Chavali; Naqi Haider; Brent A. Bell; Ying Song; Joshua L Dunaief

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):1343.

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