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Retina June 2025

Evaluation of Anti-VEGFR2 Specific Photoimmunotherapy for Targeted Regression of Neovascularization in an AMD Model

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Hideto Osada; Takashi Nishimura; Makoto Mitsunaga; Masayuki Saruta; Kazuo Tsubota; Kazuno Negishi; Toshihide Kurihara; Norimitsu Ban
TAGS: choroidal neovascularization, lasers, neovascularization, pathologic, photoimmunotherapy, vascular endothelial growth factor receptor-2, volume
Invest. Ophthalmol. Vis. Sci.. 2025; 66(6):70. https://doi.org/10.1167/iovs.66.6.70

Immunology and Microbiology March 2025

An Approach to Predict Intraocular Diseases by Machine Learning Based on Vitreous Humor Immune Mediator Profile

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Risa Sugawara; Yoshihiko Usui; Akira Saito; Naoya Nezu; Hiroyuki Komatsu; Kinya Tsubota; Masaki Asakage; Naoyuki Yamakawa; Yoshihiro Wakabayashi; Masahiro Sugimoto; Masahiko Kuroda; Hiroshi Goto
TAGS: biological response modifiers, immune mediator, machine learning, vitreous body
Invest. Ophthalmol. Vis. Sci.. 2025; 66(3):38. https://doi.org/10.1167/iovs.66.3.38

Cornea February 2025

Disruption in Autonomic Nervous Activity Is Associated With Central and Peripheral-Level in Dry Eye With Unstable Tear Film

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Minako Kaido; Reiko Arita; Yasue Mitsukura; Brian Sumali; Kazuo Tsubota
TAGS: autonomic nervous system, dry eye syndromes, eye, heart failure, nervousness, questionnaires, signs and symptoms, tear film break-up time, tear film finding, personality
Invest. Ophthalmol. Vis. Sci.. 2025; 66(2):69. https://doi.org/10.1167/iovs.66.2.69

Includes: Supplemental Content

Cornea August 2024

The Necroptosis Pathway Is Upregulated in the Cornea in Mice With Ocular Graft-Versus-Host Disease

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Kazuki Asai; Hyung Keun Lee; Shinri Sato; Eisuke Shimizu; Jaehun Jung; Takahiro Okazaki; Mamoru Ogawa; Shigeto Shimmura; Kazuo Tsubota; Yoko Ogawa; Kazuno Negishi; Masatoshi Hirayama
TAGS: cornea, graft-versus-host disease, mice, necroptosis, proteins, up-regulation (physiology)
Invest. Ophthalmol. Vis. Sci.. 2024; 65(10):38. https://doi.org/10.1167/iovs.65.10.38

Includes: Supplemental Content

ARVO Annual Meeting Abstract June 2024

Effect of optogenetic activation of superior salivatory nucleus on the choroidal thickness

Ziyan Ma; Heonuk Jeong; Tetsu Yoshida; Kam Yan KWOK; Kazuno Negishi; Kenji F Tanaka; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):85.

ARVO Annual Meeting Abstract June 2024

Violet light reduces light-induced retinal damage in a murine model

Steve S.W. Chen; Hideto Osada; Jue Wang; Kazuno Negishi; Toshihide Kurihara; Kazuo Tsubota; Norimitsu Ban

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):711.

ARVO Annual Meeting Abstract June 2024

Establishment of an in vitro choroid complex system for vascular response screening

Toshihide Kurihara; Heonuk Jeong; Kazuno Negishi; Kazuo Tsubota

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1544.

ARVO Annual Meeting Abstract June 2024

Persistence of inhibitory effect for myopia progression by violet light irradiation

Tetsu Yoshida; Heonuk Jeong; Shin-ichi Ikeda; Kazuno Negishi; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1168.

ARVO Annual Meeting Abstract June 2024

Local Depletion of Choroidal Macrophages Can Induce Myopia in Mice

Jing Hou; Shin-ichi Ikeda; Satoshi Imanishi; Kiwako Mori; Heonuk Jeong; Kazuno Negishi; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1165.

ARVO Annual Meeting Abstract June 2024

Establishment of adult murine lens-induced myopia model through prolonged induction

Yajing Yang; Yohei Tomita; Shin-ichi Ikeda; Heonuk Jeong; Xiaoyan Jiang; Deokho Lee; Kazuno Negishi; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1163.

ARVO Annual Meeting Abstract June 2024

Choroidal mast cells contribute to myopia progression of mouse lens-induced myopia model

Jue Shi; Shin-ichi Ikeda; Jing Hou; Junhan Chen; Heonuk Jeong; Kazuno Negishi; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1162.

ARVO Annual Meeting Abstract June 2024

Feature of autonomic nerve activity during different eye conditions in dry eye with unstable tear film

Minako Kaido; Reiko Arita; Yasue Mitsukura; Brian Sumali; Kazuo Tsubota

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2955.

ARVO Annual Meeting Abstract June 2024

Violet light affects local controls of vasodilation in mouse choroid

Heonuk Jeong; Kazuno Negishi; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):2821.

ARVO Annual Meeting Abstract June 2024

Clinical risk factors contributing to elongation of axial length in Vogt-Koyanagi-Harada disease

Sorano Tomimitsu; Kinya Tsubota; Mizuki Nakamura; Kazusa Koyama; Yoshihiko Usui; Yuto Kinoshita; Masaki Asakage; Chihiro Maehara; Ryota Nonaka; Risa Sugawara; Kei Wakatsuki; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3018.

ARVO Annual Meeting Abstract June 2024

ER stress contributes to the development of ocular graft-vs-host disease (GVHD) in eyelids and the ocular surface

Shinri Sato; Yoko Ogawa; Eisuke Shimizu; Shigeto Shimmura; Kazuno Negishi; Masatoshi Hirayama; Kazuo Tsubota

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):5777.

ARVO Annual Meeting Abstract June 2024

Dose-dependency of myopia suppression by 4-phenylbutic acid instillation

Shin-ichi Ikeda; Kazuno Negishi; Kazuo Tsubota; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6150.

ARVO Annual Meeting Abstract June 2024

Suppression of myopia by oral administration of Lacticaseibacillus paracasei

Kazuo Tsubota; Shin-ichi Ikeda; Kazuno Negishi; Toshihide Kurihara

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6061.

ARVO Annual Meeting Abstract June 2024

Assessment of Functionality of Smart Eye Camera: A Smartphone-attached Slit-Lamp Microscope and Fundus Camera.

Eisuke Shimizu; Yoko Ogawa; Shinri Sato; Ryota Yokoiwa; Shintaro Nakayama; Rohan Jeetendra Khemlani; Hiroki Nishimura; Masatoshi Hirayama; Kazuo Tsubota; Yasunori Sato; Shigeto Shimmura; Kazuno Negishi

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):3390.

ARVO Annual Meeting Abstract June 2024

MicroRNA Profiling in Extracellular Vesicles from Vitreous Humor and Serum of Patients with Ocular Sarcoidosis and Vitreoretinal Lymphoma

Hiroyuki Komatsu; Yoshihiko Usui; Yusuke Yoshioka; Masaki Asakage; Risa Sugawara; Kinya Tsubota; Ryo Wakita; Keiko Maruo; Takahiro Ochiya; Hiroshi Goto

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):1473.

ARVO Annual Meeting Abstract June 2024

To receive violet light indoors, human should look directly outdoors through an open window

Shinichiro Kondo; Hidemasa Torii; Xiaoyan Jiang; Jing Hou; Kazuno Negishi; Toshihide Kurihara; Kazuo Tsubota

Invest. Ophthalmol. Vis. Sci.. 2024; 65(7):6629.

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Evaluation of Anti-VEGFR2 Specific Photoimmunotherapy for Targeted Regression of Neovascularization in an AMD Model

An Approach to Predict Intraocular Diseases by Machine Learning Based on Vitreous Humor Immune Mediator Profile

Disruption in Autonomic Nervous Activity Is Associated With Central and Peripheral-Level in Dry Eye With Unstable Tear Film

The Necroptosis Pathway Is Upregulated in the Cornea in Mice With Ocular Graft-Versus-Host Disease

Effect of optogenetic activation of superior salivatory nucleus on the choroidal thickness

Violet light reduces light-induced retinal damage in a murine model

Establishment of an in vitro choroid complex system for vascular response screening

Persistence of inhibitory effect for myopia progression by violet light irradiation

Local Depletion of Choroidal Macrophages Can Induce Myopia in Mice

Establishment of adult murine lens-induced myopia model through prolonged induction

Choroidal mast cells contribute to myopia progression of mouse lens-induced myopia model

Feature of autonomic nerve activity during different eye conditions in dry eye with unstable tear film

Violet light affects local controls of vasodilation in mouse choroid

Clinical risk factors contributing to elongation of axial length in Vogt-Koyanagi-Harada disease

ER stress contributes to the development of ocular graft-vs-host disease (GVHD) in eyelids and the ocular surface

Dose-dependency of myopia suppression by 4-phenylbutic acid instillation

Suppression of myopia by oral administration of Lacticaseibacillus paracasei

Assessment of Functionality of Smart Eye Camera: A Smartphone-attached Slit-Lamp Microscope and Fundus Camera.

MicroRNA Profiling in Extracellular Vesicles from Vitreous Humor and Serum of Patients with Ocular Sarcoidosis and Vitreoretinal Lymphoma

To receive violet light indoors, human should look directly outdoors through an open window

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