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ARVO Annual Meeting Abstract June 2015

Novel CCR3 antagonists are effective mono- and combination inhibitors of CNV growth and vascular permeability

Yin Shan Eric Ng; Norihiro Nagai; Meihua Ju; Kanako Izumi-Nagai; Scott Robbie; James W B Bainbridge; Achim H Krauss; David C Gale; Peter S Adamson; David Shima

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):2290. doi:

Translational Research June 2014

Spontaneous CNV in a Novel Mutant Mouse Is Associated With Early VEGF-A–Driven Angiogenesis and Late-Stage Focal Edema, Neural Cell Loss, and Dysfunction

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Norihiro Nagai; Pete Lundh von Leithner; Kanako Izumi-Nagai; Brett Hosking; Bo Chang; Ron Hurd; Peter Adamson; Anthony P. Adamis; Richard H. Foxton; Yin Shan Ng; David T. Shima
TAGS: choroidal neovascularization, edema, mice, pathophysiology, vascular endothelial growth factor a, angiogenesis, neurons
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3709-3719. doi: https://doi.org/10.1167/iovs.14-13989

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract June 2013

Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration

Misa Suzuki; Norihiro Nagai; Kanako Izumi-Nagai; Hajime Shinoda; Takashi Koto; Atsuro Uchida; HIroshi Mochimaru; Kenya Yuki; Kazuo Tsubota; Yoko Ozawa; Laboratory of Retinal Cell Biology,Keio University Center for Integrated Medical Research

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):4093. doi:

ARVO Annual Meeting Abstract March 2012

Novel Ccr3 Antagonists Are Effective Mono- And Combination Inhibitors Of Cnv Growth And Vascular Permeability

Norihiro Nagai; Kanako Izumi-Nagai; Scott J. Robbie; James W. Bainbridge; Peter S. Adamson; Yin-shan Ng; David T. Shima

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):1670. doi:

ARVO Annual Meeting Abstract April 2011

Spontaneous Cnv In A Novel Mutant Mouse Is Associated With Early Chorio-retinal Para-inflammation And Vegf Driven Angiogenesis

Norihiro Nagai; Kanako Izumi-Nagai; Scott Robbie; James W. Bainbridge; Bo Chang; Ronald Hurd; Yin-shan Ng; David T. Shima

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1015. doi:

ARVO Annual Meeting Abstract April 2010

A Novel Murine Model for Wet AMD With Spontaneous and Multifocal Choroidal Neovascularization

N. Nagai; K. Izumi-Nagai; B. Chang; N. Hawes; Y.-S. Ng; D. T. Shima

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):6142. doi:

Retinal Cell Biology April 2009

CTGF Is Increased in Basal Deposits and Regulates Matrix Production through the ERK (p42/p44 mapk ) MAPK and the p38 MAPK Signaling Pathways

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Norihiro Nagai; Alena Klimava; Wen-Hsiang Lee; Kanako Izumi-Nagai; James T. Handa
TAGS: connective tissue growth factor, mitogen-activated protein kinase p38, mitogen-activated protein kinases, signal pathway, signal transduction pathways, gelatinase a, fibronectins
Invest. Ophthalmol. Vis. Sci.. 2009; 50(4):1903-1910. doi: https://doi.org/10.1167/iovs.08-2383

ARVO Annual Meeting Abstract May 2008

Inhibition of Choroidal Neovascularization With an Anti-Inflammatory Carotenoid Astaxanthin

K. Izumi-Nagai; N. Nagai; K. Ohgami; S. Satofuka; Y. Ozawa; K. Tsubota; S. Ohno; Y. Oike; S. Ishida

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):533. doi:

Retinal Cell Biology April 2008

Inhibition of Choroidal Neovascularization with an Anti-Inflammatory Carotenoid Astaxanthin

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Kanako Izumi-Nagai; Norihiro Nagai; Kazuhiro Ohgami; Shingo Satofuka; Yoko Ozawa; Kazuo Tsubota; Shigeaki Ohno; Yuichi Oike; Susumu Ishida
TAGS: carotenoids, choroidal neovascularization, anti-inflammatory agents, macrophages
Invest. Ophthalmol. Vis. Sci.. 2008; 49(4):1679-1685. doi: https://doi.org/10.1167/iovs.07-1426

Retinal Cell Biology September 2007

Eicosapentaenoic Acid Is Anti-Inflammatory in Preventing Choroidal Neovascularization in Mice

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Takashi Koto; Norihiro Nagai; Hiroshi Mochimaru; Toshihide Kurihara; Kanako Izumi-Nagai; Shingo Satofuka; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Yuichi Oike; Susumu Ishida
TAGS: anti-inflammatory agents, choroidal neovascularization, mice, eicosapentaenoic acid, peroxisome proliferator-activated receptors, choroid, molecule
Invest. Ophthalmol. Vis. Sci.. 2007; 48(9):4328-4334. doi: https://doi.org/10.1167/iovs.06-1148

Retinal Cell Biology September 2007

Suppression of Diabetes-Induced Retinal Inflammation by Blocking the Angiotensin II Type 1 Receptor or Its Downstream Nuclear Factor-κB Pathway

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Norihiro Nagai; Kanako Izumi-Nagai; Yuichi Oike; Takashi Koto; Shingo Satofuka; Yoko Ozawa; Kenji Yamashiro; Makoto Inoue; Kazuo Tsubota; Kazuo Umezawa; Susumu Ishida
TAGS: diabetes mellitus, diabetes mellitus, type 2, inflammation, intercellular adhesion molecule 1, receptor, angiotensin, type 1, vascular endothelial growth factor a, leukocytes, retina
Invest. Ophthalmol. Vis. Sci.. 2007; 48(9):4342-4350. doi: https://doi.org/10.1167/iovs.06-1473

ARVO Annual Meeting Abstract May 2007

Anti-Inflammatory Effect of Eicosapentaenoic Acid on Diabetic Retina in vivo and Cytokine Expression in vitro

T. Koto; N. Nagai; H. Mochimaru; K. Izumi-Nagai; S. Satofuka; H. Shinoda; T. Kurihara; Y. Ozawa; K. Tsubota; S. Ishida

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1360. doi:

ARVO Annual Meeting Abstract May 2007

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin

N. Nagai; Y. Oike; K. Izumi-Nagai; T. Koto; S. Satofuka; H. Shinoda; Y. Ozawa; M. Inoue; K. Tsubota; S. Ishida

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):1467. doi:

Retinal Cell Biology May 2007

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin

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Norihiro Nagai; Yuichi Oike; Kanako Izumi-Nagai; Takashi Koto; Shingo Satofuka; Hajime Shinoda; Kousuke Noda; Yoko Ozawa; Makoto Inoue; Kazuo Tsubota; Susumu Ishida
TAGS: choroidal neovascularization, angiotensin-converting enzyme, bradykinin, vascular endothelial growth factor a, intercellular adhesion molecule 1, monocyte chemoattractant protein-1
Invest. Ophthalmol. Vis. Sci.. 2007; 48(5):2321-2326. doi: https://doi.org/10.1167/iovs.06-1296

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Novel CCR3 antagonists are effective mono- and combination inhibitors of CNV growth and vascular permeability

Spontaneous CNV in a Novel Mutant Mouse Is Associated With Early VEGF-A–Driven Angiogenesis and Late-Stage Focal Edema, Neural Cell Loss, and Dysfunction

Baseline characteristics and response to intravitreal ranibizumab therapy for age-related macular degeneration

Novel Ccr3 Antagonists Are Effective Mono- And Combination Inhibitors Of Cnv Growth And Vascular Permeability

Spontaneous Cnv In A Novel Mutant Mouse Is Associated With Early Chorio-retinal Para-inflammation And Vegf Driven Angiogenesis

A Novel Murine Model for Wet AMD With Spontaneous and Multifocal Choroidal Neovascularization

CTGF Is Increased in Basal Deposits and Regulates Matrix Production through the ERK (p42/p44 mapk ) MAPK and the p38 MAPK Signaling Pathways

Inhibition of Choroidal Neovascularization With an Anti-Inflammatory Carotenoid Astaxanthin

Inhibition of Choroidal Neovascularization with an Anti-Inflammatory Carotenoid Astaxanthin

Eicosapentaenoic Acid Is Anti-Inflammatory in Preventing Choroidal Neovascularization in Mice

Suppression of Diabetes-Induced Retinal Inflammation by Blocking the Angiotensin II Type 1 Receptor or Its Downstream Nuclear Factor-κB Pathway

Anti-Inflammatory Effect of Eicosapentaenoic Acid on Diabetic Retina in vivo and Cytokine Expression in vitro

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin

Suppression of Choroidal Neovascularization by Inhibiting Angiotensin-Converting Enzyme: Minimal Role of Bradykinin

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