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ARVO Annual Meeting Abstract June 2022

Isolation of trabecular meshwork (TM) RNA and analysis of gene expression following serial bevacizumab injections in rat eyes.

Eliesa Ing; William Cepurna; Diana C Lozano; Virginia O'Callahan; Yong-Feng Yang; Fountane Chan; Kate E Keller; John C Morrison

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2703 – A0067. doi:

ARVO Annual Meeting Abstract June 2022

αvβ3 Integrin Expression in the Human Trabecular Meshwork/Schlemm’s Canal Pathway (TM/SC) is Age Dependent and Segmental

Jennifer A Faralli; Mark Filla; Haania Khan; Kate E Keller; Donna M Peters

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3302 – A0402. doi:

ARVO Annual Meeting Abstract June 2022

Effects of biomechanical cues on filopodia, tunneling nanotubes, and myosin-X in trabecular meshwork cells

Kate E Keller; Ying YIng Sun; Yong-Feng Yang

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3300 – A0400. doi:

ARVO Annual Meeting Abstract June 2022

Artificial intelligence-integrated approaches in ophthalmology: A qualitative pilot study of provider understanding and adoption of AI

Erin L. Robinson; Giovanna Guidoboni; Alice Verticchio; Ryan Zukerman; James Keller; Brent A Siesky; Alon Harris

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):729 – F0457. doi:

ARVO Annual Meeting Abstract June 2022

Physiology-informed Transfer Learning reveals differences in choroidal thickness categorized by hemodynamic and intraocular pressure dynamics

Ryan Zukerman; Alon Harris; Louis Pasquale; Aaron Beckwith; Rajat Rai; James Keller; Christopher Wikle; Erin L. Robinson; Maggie Lin; Daphne Zou; Brent A Siesky; Alice Chandra Verticchio Vercellin; Janet Coleman-Belin; Roberto Nunez; Giovanna Guidoboni

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2020 – A0461. doi:

ARVO Annual Meeting Abstract June 2022

Transfer Learning reveals differences in arterio-venous oxygenation biomarkers in patients with glaucoma and healthy controls

Lucas William Rowe; Alon Harris; Giovanna Guidoboni; Alice Chandra Verticchio Vercellin; Aaron Beckwith; Rajat Rai; James Keller; Christopher Wikle; Erin L. Robinson; Maggie Lin; Daphne Zou; Amber Wolf; Roberto Nunez; Danny Kim; Brent A Siesky

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2019 – A0460. doi:

ARVO Annual Meeting Abstract June 2022

Challenges in the characterization of the ocular surface microbiome

Elio Herzog; Irene Keller; Sebastian Wolf; Martin Sebastian Zinkernagel; Denise Corinne Zysset-Burri

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):1682 – A0512. doi:

ARVO Annual Meeting Abstract June 2022

Clarifying the roles of high and low blood pressure in glaucoma via physiology-informed machine learning

Roberto Nunez; Alon Harris; Marcela Szopos; Rajat Rai; James Keller; Christopher Wikle; Erin L. Robinson; Maggie Lin; Daphne Zou; Alice Verticchio; Brent A Siesky; Giovanna Guidoboni

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):3113. doi:

ARVO Annual Meeting Abstract June 2022

Physiology-informed machine learning to enable precision medical approaches of intraocular pressure and blood pressure management in glaucoma

Giovanna Guidoboni; Daphne Zou; Maggie Lin; Roberto Nunez; Rajat Rai; James Keller; Christopher Wikle; Erin L. Robinson; Alice Verticchio; Brent A Siesky; Alon Harris

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2293. doi:

ARVO Annual Meeting Abstract June 2022

Vascular physiology-informed machine learning to identify similar subgroups of glaucoma patients across studies: Indianapolis Glaucoma Progression Study, Thessaloniki Eye Study, and Singapore Epidemiology of Eye Disease Study

Daphne Zou; Giovanna Guidoboni; James Keller; Christopher Wikle; Erin L. Robinson; Rajat Rai; Maggie Lin; Roberto Nunez; Alice Verticchio; Brent A Siesky; Fotis Topouzis; Dimitrios Giannoulis; Vassilis Kilintzis; Ching-Yu Cheng; Rachel S Chong; Alon Harris

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2023 – A0464. doi:

ARVO Annual Meeting Abstract June 2022

Physiology-informed Transfer Learning Reveals Differences in Optical Coherence Tomography Angiography Vascular Biomarkers

Aaron Beckwith; Alon Harris; Roberto Nunez; Maggie Lin; Daphne Zou; Rajat Rai; James Keller; Christopher Wikle; Erin L. Robinson; Brent A Siesky; Alice Verticchio; Giovanna Guidoboni

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):2905 – F0058. doi:

ARVO Annual Meeting Abstract June 2022

Physiology-enhanced data analysis of the Thessaloniki Eye Study: relationship between intraocular pressure and venous resistance

Rajat Rai; Giovanna Guidoboni; James Keller; Daphne Zou; Christopher Wikle; Erin L. Robinson; Maggie Lin; Roberto Nunez; Brent A Siesky; Alice Verticchio; Barbara M Wirostko; Dimitrios Giannoulis; Vassilis Kilintzis; Fotis Topouzis; Alon Harris

Invest. Ophthalmol. Vis. Sci.. 2022; 63(7):4033 – A0418. doi:

Perspective February 2022

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

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Colleen M. McDowell; Krishnakumar Kizhatil; Michael H. Elliott; Darryl R. Overby; Joseph van Batenburg-Sherwood; J. Cameron Millar; Markus H. Kuehn; Gulab Zode; Ted S. Acott; Michael G. Anderson; Sanjoy K. Bhattacharya; Jacques A. Bertrand; Terete Borras; Diane E. Bovenkamp; Lin Cheng; John Danias; Michael Lucio De Ieso; Yiqin Du; Jennifer A. Faralli; Rudolf Fuchshofer; Preethi S. Ganapathy; Haiyan Gong; Samuel Herberg; Humberto Hernandez; Peter Humphries; Simon W. M. John; Paul L. Kaufman; Kate E. Keller; Mary J. Kelley; Ruth A. Kelly; David Krizaj; Ajay Kumar; Brian C. Leonard; Raquel L. Lieberman; Paloma Liton; Yutao Liu; Katy C. Liu; Navita N. Lopez; Weiming Mao; Timur Mavlyutov; Fiona McDonnell; Gillian J. McLellan; Philip Mzyk; Andrews Nartey; Louis R. Pasquale; Gaurang C. Patel; Padmanabhan P. Pattabiraman; Donna M. Peters; Vijaykrishna Raghunathan; Ponugoti Vasantha Rao; Naga Rayana; Urmimala Raychaudhuri; Ester Reina-Torres; Ruiyi Ren; Douglas Rhee; Uttio Roy Chowdhury; John R. Samples; E. Griffen Samples; Najam Sharif; Joel S. Schuman; Val C. Sheffield; Cooper H. Stevenson; Avinash Soundararajan; Preeti Subramanian; Chenna Kesavulu Sugali; Yang Sun; Carol B. Toris; Karen Y. Torrejon; Amir Vahabikashi; Janice A. Vranka; Ting Wang; Colin E. Willoughby; Chen Xin; Hongmin Yun; Hao F. Zhang; Michael P. Fautsch; Ernst R. Tamm; Abbot F. Clark; C. Ross Ethier; W. Daniel Stamer
TAGS: eye, mice, ocular hypertension, intraocular pressure, perfusion
Invest. Ophthalmol. Vis. Sci.. 2022; 63(2):12. doi: https://doi.org/10.1167/iovs.63.2.12

Immunology and Microbiology August 2021

Understanding the Interactions Between the Ocular Surface Microbiome and the Tear Proteome

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Denise C. Zysset-Burri; Irina Schlegel; Joel-Benjamin Lincke; Damian Jaggi; Irene Keller; Manfred Heller; Sophie Braga Lagache; Sebastian Wolf; Martin S. Zinkernagel
TAGS: microbiome, proteome, comprehension
Invest. Ophthalmol. Vis. Sci.. 2021; 62(10):8. doi: https://doi.org/10.1167/iovs.62.10.8

ARVO Annual Meeting Abstract June 2021

Physiology-enhanced data analytics to evaluate the role of ocular hemodynamics in glaucoma progression

Omar Ibrahim; Alon Harris; Daphne Zou; Nicholas Mattia Marazzi; James Keller; Brent A Siesky; Alice Chandra Verticchio Vercellin; Ryan Zukerman; Giovanna Guidoboni

Invest. Ophthalmol. Vis. Sci.. 2021; 62(8):2578. doi:

Immunology and Microbiology January 2021

Panton-Valentine Leucocidin of Staphylococcus aureus Induces Oxidative Stress and Neurotransmitter Imbalance in a Retinal Explant Model

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Mathieu Wurtz; Elisa Ruhland; XuanLi Liu; Izzie-Jacques Namer; Viola Mazzoleni; Dan Lipsker; Daniel Keller; Gilles Prévost; David Gaucher

Invest. Ophthalmol. Vis. Sci.. 2021; 62(1):4. doi: https://doi.org/10.1167/iovs.62.1.4

ARVO Annual Meeting Abstract June 2020

Tunneling nanotube formation by normal and glaucomatous trabecular meshwork cells in response to mechanical stretch

Kate Keller; Ying Ying Sun; Yong-feng Yang

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2331. doi:

ARVO Annual Meeting Abstract June 2020

In-vitro measurements from porcine retinal tissue stimulated by a photovoltaic implant with 3D carbon electrodes

Rasmus Schmidt Davidsen; Olga Kudryavtseva; Stephan Sylvest Keller; Ole Hansen; Toke Bek

Invest. Ophthalmol. Vis. Sci.. 2020; 61(7):2201. doi:

Glaucoma November 2019

Phenotypic and Functional Alterations in Tunneling Nanotubes Formed by Glaucomatous Trabecular Meshwork Cells

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Ying Ying Sun; John M. Bradley; Kate E. Keller
TAGS: actins, glaucoma, immunohistochemistry, phenotype, trabecular meshwork, transfer technique, vesicle, body tissue, diagnostic imaging
Invest. Ophthalmol. Vis. Sci.. 2019; 60(14):4583-4595. doi: https://doi.org/10.1167/iovs.19-28084

Includes: Multimedia, Supplemental Content

ARVO Annual Meeting Abstract July 2019

Identification of extracellular matrix gene variants in a large glaucoma family and analysis of human trabecular meshwork cells harboring one or more of these variants.

Kate E Keller; Ying Ying Sun; Yong-Feng Yang; Renee Sykes; Douglas Keene; John R Samples; Mary Wirtz

Invest. Ophthalmol. Vis. Sci.. 2019; 60(9):5145. doi:

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Isolation of trabecular meshwork (TM) RNA and analysis of gene expression following serial bevacizumab injections in rat eyes.

αvβ3 Integrin Expression in the Human Trabecular Meshwork/Schlemm’s Canal Pathway (TM/SC) is Age Dependent and Segmental

Effects of biomechanical cues on filopodia, tunneling nanotubes, and myosin-X in trabecular meshwork cells

Artificial intelligence-integrated approaches in ophthalmology: A qualitative pilot study of provider understanding and adoption of AI

Physiology-informed Transfer Learning reveals differences in choroidal thickness categorized by hemodynamic and intraocular pressure dynamics

Transfer Learning reveals differences in arterio-venous oxygenation biomarkers in patients with glaucoma and healthy controls

Challenges in the characterization of the ocular surface microbiome

Clarifying the roles of high and low blood pressure in glaucoma via physiology-informed machine learning

Physiology-informed machine learning to enable precision medical approaches of intraocular pressure and blood pressure management in glaucoma

Vascular physiology-informed machine learning to identify similar subgroups of glaucoma patients across studies: Indianapolis Glaucoma Progression Study, Thessaloniki Eye Study, and Singapore Epidemiology of Eye Disease Study

Physiology-informed Transfer Learning Reveals Differences in Optical Coherence Tomography Angiography Vascular Biomarkers

Physiology-enhanced data analysis of the Thessaloniki Eye Study: relationship between intraocular pressure and venous resistance

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

Understanding the Interactions Between the Ocular Surface Microbiome and the Tear Proteome

Physiology-enhanced data analytics to evaluate the role of ocular hemodynamics in glaucoma progression

Panton-Valentine Leucocidin of Staphylococcus aureus Induces Oxidative Stress and Neurotransmitter Imbalance in a Retinal Explant Model

Tunneling nanotube formation by normal and glaucomatous trabecular meshwork cells in response to mechanical stretch

In-vitro measurements from porcine retinal tissue stimulated by a photovoltaic implant with 3D carbon electrodes

Phenotypic and Functional Alterations in Tunneling Nanotubes Formed by Glaucomatous Trabecular Meshwork Cells

Identification of extracellular matrix gene variants in a large glaucoma family and analysis of human trabecular meshwork cells harboring one or more of these variants.

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