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Meeting Abstract (25)
Journal Articles (3)

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Investigative Ophthalmology & Visual Science (28)

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ARVO Annual Meeting Abstract (25)
Cornea (2)
Biochemistry and Molecular Biology (1)

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Cornea (3)
Eye Anatomy and Disorders (2)
Biochemistry and Molecular Biology (1)
Pharmacology (1)

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cornea (2)
corneal epithelium (2)
mice (2)
conjunctiva (1)
debridement (1)
emodin (1)
epithelium (1)
healing process (1)
impairment (1)
interleukin-6 (1)

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ARVO Annual Meeting Abstract June 2015

Impairment of cornea epithelium wound healing in a TRPA1-deficient mouse

Yuka Okada; Kumi Shirai; Peter S Reinach; Masayasu Miyajima; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2015; 56(7 ):703.

Biochemistry and Molecular Biology June 2014

Effects of the Loss of Conjunctival Muc16 on Corneal Epithelium and Stroma in Mice

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Kumi Shirai; Yuka Okada; Dong-Joo Cheon; Masayasu Miyajima; Richard R. Behringer; Osamu Yamanaka; Shizuya Saika
TAGS: conjunctiva, cornea, corneal epithelium, mice
Invest. Ophthalmol. Vis. Sci.. 2014; 55(6):3626-3637. https://doi.org/10.1167/iovs.13-12955

Cornea May 2014

Impairment of Corneal Epithelial Wound Healing in a TRPV1-Deficient Mouse

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Takayoshi Sumioka; Yuka Okada; Peter S. Reinach; Kumi Shirai; Masayasu Miyajima; Osamu Yamanaka; Shizuya Saika
TAGS: cornea, epithelium, interleukin-6, mice, substance p, trpv1 receptor, wound healing, healing process, debridement, corneal epithelium
Invest. Ophthalmol. Vis. Sci.. 2014; 55(5):3295-3302. https://doi.org/10.1167/iovs.13-13077

ARVO Annual Meeting Abstract June 2013

Impaired angiogenic response in cornea by lacking TRPV1 in mice

Katsuo Tomoyose; Yuka Okada; Takayoshi Sumioka; Kumi Shirai; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2092.

ARVO Annual Meeting Abstract June 2013

Lacking Muc16 affects intra-epithelial differentiation and wound healing in corneal epithelium in mice

Shizuya Saika; Kumi Shirai; Yuka Okada; Masayasu Miyajima; Dong-Joo Cheon; Richard Behringer

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):2577.

ARVO Annual Meeting Abstract June 2013

Favorable effects of loss of TRPM2 on the inflammation and scarring in an alkali-burned cornea in mice

Yuka Okada; Kumi Shirai; Masayasu Miyajima; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2013; 54(15):3906.

ARVO Annual Meeting Abstract March 2012

Impaired Epithelial Wound Healing In A Mouse Model Of Neurotrophic Keratopathy

Yuka Okada; Kumi Shirai; Emiko Senba; Norihito Fujita; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2012; 53(14):3564.

ARVO Annual Meeting Abstract April 2011

Characterization of Early Open Eyelid Rat (EOEL rat)

Masayasu Miyajima; Yuka Okada; Kumi Shirai; Shizuya Saika; Kazushige Sakaguchi

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):1950.

ARVO Annual Meeting Abstract April 2011

Effects Of Loss Of TRPV4 On The Inflammation And Scarring Of An Alkali-burned Cornea In Mice

Yuka Okada; Peter S. Reinach; Kumi Shirai; Ai Kitano; Masayasu Miyajima; Shizuya Saika

Invest. Ophthalmol. Vis. Sci.. 2011; 52(14):2022.

ARVO Annual Meeting Abstract April 2010

Trpa1 Gene Ablation in Mice Improves Corneal Wound Healing Response to Injury

Y. Okada; P. S. Reinach; K. Shirai; A. Kitano; M. Miyajima; S. Saika

Invest. Ophthalmol. Vis. Sci.. 2010; 51(13):2496.

ARVO Annual Meeting Abstract April 2009

Phosphorylation Status of Smad2/3 in Tissues of Human Post-Operative Capsular Opacification

S. Saika; S.-I. Tanaka; K.-I. Miyazaki; K. Shirai

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):2126.

ARVO Annual Meeting Abstract April 2009

A Histone Deacetylase Inhibitor, Trichostatin A, Suppresses TGFb/Smad Signal and Has a Therapeutic Effects on Experimental Alkali Burn in Mice

A. Kitano; O. Yamanaka; Y. Okada; K. Shirai; S. Saika

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3065.

ARVO Annual Meeting Abstract April 2009

Effects of Loss of Trpv1 on the Inflammation After an Alkali-Burned Cornea in Mice

Y. Okada; S. Saika; K. Shirai; A. Kitano; M. Miyajima; P. S. Reinach

Invest. Ophthalmol. Vis. Sci.. 2009; 50(13):3069.

ARVO Annual Meeting Abstract May 2008

Reduced Inflammation and Scarring During Corneal Wound Healing in TRPV1 Knockout Mice

Y. Okada; S. Saika; K. Shirai; M. Miyajima; W. W. Kao; P. Reinach

Invest. Ophthalmol. Vis. Sci.. 2008; 49(13):2939.

Cornea November 2007

Emodin Suppression of Ocular Surface Inflammatory Reaction

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Ai Kitano; Shizuya Saika; Osamu Yamanaka; Kazuo Ikeda; Yuka Okada; Kumi Shirai; Peter S. Reinach
TAGS: emodin, tumor necrosis factors
Invest. Ophthalmol. Vis. Sci.. 2007; 48(11):5013-5022. https://doi.org/10.1167/iovs.07-0393

ARVO Annual Meeting Abstract May 2007

Effect of Tetrandrine on Fibrogenic Behaviors of Cultured Human Subconjunctival Fibroblasts

A. Kitano; O. Yamanaka; S. Saika; K. Ikeda; Y. Okada; K. Shirai; Y. Ohnishi

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):4280.

ARVO Annual Meeting Abstract May 2007

Effects of Topical Anti-Glaucoma Medications on Ocular Surface as Evaluated by Gene Expression Pattern

Y. Okada; S. Saika; T. Ueyama; K. Shirai; O. Yamanaka; Y. Ohnishi; P. S. Reinach

Invest. Ophthalmol. Vis. Sci.. 2007; 48(13):4814.

ARVO Annual Meeting Abstract May 2006

Epidermal Growth Factor Induces C–Fos Expression and Wound Closure in Human Corneal Epithelial Cell Line

Y. Okada; S. Saika; K. Shirai; O. Yamanaka; Y. Ohnishi; P.S. Reinach

Invest. Ophthalmol. Vis. Sci.. 2006; 47(13):5044.

ARVO Annual Meeting Abstract May 2005

AP–1 and COX–2 Expression in Corneal Epithelium Following Anti–Glaucomatous Eyedrops

Y. Okada; S. Saika; K. Shirai; T. Miyamoto; O. Yamanaka; T. Ueyama; Y. Ohnishi

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):2115.

ARVO Annual Meeting Abstract May 2005

The Effects of EGF and TGFb to Corneal Endothelium Spreading

T. Sumioka; Y. Okada; T. Miyamoto; K. Shirai; S. Saika; Y. Ohnishi

Invest. Ophthalmol. Vis. Sci.. 2005; 46(13):4512.

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